The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Pseudomonas aeruginosa adapts its iron uptake strategies in function of the type of infections
Open accessAbstract
Pseudomonas aeruginosa is a Gram-negative γ-Proteobacterium which is known for its capacity to colonize various niches, including some invertebrate and vertebrate hosts, making it one of the most frequent bacteria causing opportunistic infections. P. aeruginosa is able to cause acute as well as chronic infections and it uses different colonization and virulence factors to do so. Infections range from septicemia, urinary infections, burn wound colonization, and chronic colonization of the lungs of cystic fibrosis patients. Like the vast majority of organisms, P. aeruginosa needs iron to sustain growth. P. aeruginosa utilizes different strategies to take up iron, depending on the type of infection it causes. Two siderophores are produced by this bacterium, pyoverdine and pyochelin, characterized by high and low affinities for iron respectively. P. aeruginosa is also able to utilize different siderophores from other microorganisms (siderophore piracy). It can also take up heme from hemoproteins via two different systems. Under microaerobic or anaerobic conditions, P. aeruginosa is also able to take up ferrous iron via its Feo system using redox-cycling phenazines. Depending on the type of infection, P. aeruginosa can therefore adapt by switching from one iron uptake system to another as we will describe in this short review.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Many pathogens, such as P. aeruginosa, are able to intercept siderophores from neighboring bacteria when Fe starved.21”
From Bacterial Responses to Iron Withholding by Calprotectin (2021) · cites this paper as [21]
In the citing paper
“it has been observed that P. aeruginosa adapts its Fe acquisition strategies to prioritize Fe(III) or Fe(II) uptake in aerobic or anaerobic settings, respectively.21”
From Bacterial Responses to Iron Withholding by Calprotectin (2021) · cites this paper as [21]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Andrews, S. C., Robinson, A. K., & Rodríguez-Quiñones, F. (2003) · FEMS Microbiology Reviews · doi:10.1016/s0168-6445(03)00055-x · Cited by 2,702 · cited 4×
“Iron is the fourth most abundant element on earth and it is widely used by organisms because it can exist in two oxidation states, Fe2+ and Fe3+, which is why it is involved in numerous oxido-reduction reactions (Andrews et al., 2003).”
BackgroundInfluentialChemistry and biology of siderophores
Hider, R. C., & Kong, X. (2010) · Natural Product Reports · doi:10.1039/b906679a · Cited by 1,722
Chemical aspects of siderophore mediated iron transport
Boukhalfa, H., & Crumbliss, A. L. (2002) · Biometals · doi:10.1023/a:1020218608266 · Cited by 547
Ochsner, U. A., Johnson, Z., & Vasil, M. L. (2000) · Microbiology · doi:10.1099/00221287-146-1-185 · Cited by 310
Pukatzki, S., Kessin, R. H., & Mekalanos, J. J. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.052704399 · Cited by 289
Phenazine-1-carboxylic acid promotes bacterial biofilm development via ferrous iron acquisition
Wang, Y., Wilks, J. C., Danhorn, T., Ramos, I., Croal, L., & Newman, D. K. (2011) · Journal of Bacteriology · doi:10.1128/jb.00396-11 · Cited by 239
Wyckoff, E. E., Lopreato, G. F., Tipton, K. A., & Payne, S. M. (2005) · Journal of Bacteriology · doi:10.1128/jb.187.16.5658-5664.2005 · Cited by 69
Cited by
Bacterial siderophores in community and host interactions
Kramer, J., Özkaya, Ö., & Kümmerli, R. (2020) · Nature Reviews Microbiology · doi:10.1038/s41579-019-0284-4 · Cited by 998
Oleńska, E., Małek, W., Wójcik, M., Swiecicka, I., Thijs, S., & Vangronsveld, J. (2020) · Science of The Total Environment · doi:10.1016/j.scitotenv.2020.140682 · Cited by 555
Role of Iron Uptake Systems in Pseudomonas aeruginosa Virulence and Airway Infection
Minandri, F., Imperi, F., Frangipani, E., Bonchi, C., Visaggio, D., Facchini, M., Pasquali, P., Bragonzi, A., & Visca, P. (2016) · Infection and Immunity · doi:10.1128/iai.00098-16 · Cited by 228
Klebba, P. E., Newton, S. M. C., Six, D. A., Kumar, A., Yang, T., Nairn, B. L., Munger, C., & Chakravorty, S. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c01005 · Cited by 150
Sass, G., Nazik, H., Penner, J., Shah, H., Ansari, S. R., Clemons, K. V., Groleau, M.-C., Dietl, A.-M., Visca, P., Haas, H., et al. (2018) · Journal of Bacteriology · doi:10.1128/jb.00345-17 · Cited by 128
Metadata
- Authors
- Cornelis, P., & Dingemans, J.
- Venue
- Frontiers in Cellular and Infection Microbiology
- Publisher
- Frontiers Media SA
- Published
- 2013
- Volume
- 3
- Pages
- 75-75
- ISSN
- 2235-2988 (ISSN-L)
- OpenAlex
- W1964092670
- Cited by
- 382
- References
- 7
- FWCI
- 6.86
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Pseudomonas aeruginosa adapts its iron uptake strategies in function of the type of infections. https://app.cochat.ai/papers/10.3389/fcimb.2013.00075
- The paper
- Cornelis, P., & Dingemans, J. (2013). Pseudomonas aeruginosa adapts its iron uptake strategies in function of the type of infections. Frontiers in Cellular and Infection Microbiology. https://doi.org/10.3389/fcimb.2013.00075
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
