The DOI matches its Crossref record; 284 of the 284 references it cites were found in a registry or an index.
The Gut Microbiota (Microbiome) in Cardiovascular Disease and Its Therapeutic Regulation
Open accessAbstract
In the last two decades, considerable interest has been shown in understanding the development of the gut microbiota and its internal and external effects on the intestine, as well as the risk factors for cardiovascular diseases (CVDs) such as metabolic syndrome. The intestinal microbiota plays a pivotal role in human health and disease. Recent studies revealed that the gut microbiota can affect the host body. CVDs are a leading cause of morbidity and mortality, and patients favor death over chronic kidney disease. For the function of gut microbiota in the host, molecules have to penetrate the intestinal epithelium or the surface cells of the host. Gut microbiota can utilize trimethylamine, N-oxide, short-chain fatty acids, and primary and secondary bile acid pathways. By affecting these living cells, the gut microbiota can cause heart failure, atherosclerosis, hypertension, myocardial fibrosis, myocardial infarction, and coronary artery disease. Previous studies of the gut microbiota and its relation to stroke pathogenesis and its consequences can provide new therapeutic prospects. This review highlights the interplay between the microbiota and its metabolites and addresses related interventions for the treatment of CVDs.
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2 retracted
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Cited by
Lagoumintzis, G., & Patrinos, G. P. (2023) · Human Genomics · doi:10.1186/s40246-023-00561-w · Cited by 132
The Gut–Brain–Microbiota Connection and Its Role in Autism Spectrum Disorders
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Inflammation: Is It a Healer, Confounder, or a Promoter of Cardiometabolic Risks?
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“For instance, dysbiosis can lead to increased intestinal permeability, allowing endotoxins such as lipo-polysaccharides to enter the bloodstream and trigger inflammatory responses that exacerbate hepatic steatosis and fibrosis [36].”
Metadata
- Authors
- Rahman, M. M., Islam, F., -Or-Rashid, M. H., Mamun, A. A., Rahaman, M. S., Islam, M. M., Meem, A. F. K., Sutradhar, P. R., Mitra, S., Mimi, A. A., Emran, T. B., Fatimawali, Idroes, R., Tallei, T. E., Ahmed, M., & Cavalu, S.
- Venue
- Frontiers in Cellular and Infection Microbiology
- Publisher
- Frontiers Media SA
- Published
- 2022-06-20
- Volume
- 12
- Pages
- 903570-903570
- ISSN
- 2235-2988 (ISSN-L)
- OpenAlex
- W4283170263
- Cited by
- 253
- References
- 284
- FWCI
- 15.26
- Type
- journal article
- Language
- en
- Open access
- gold
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- Rahman, M. M., Islam, F., -Or-Rashid, M. H., Mamun, A. A., Rahaman, M. S., Islam, M. M., Meem, A. F. K., Sutradhar, P. R., Mitra, S., Mimi, A. A., Emran, T. B., Fatimawali, Idroes, R., Tallei, T. E., Ahmed, M., & Cavalu, S. (2022). The Gut Microbiota (Microbiome) in Cardiovascular Disease and Its Therapeutic Regulation. Frontiers in Cellular and Infection Microbiology. https://doi.org/10.3389/fcimb.2022.903570
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
