Cited by 199Medication Adherence and ComplianceArtificial Intelligence in Healthcare and EducationMobile Health and mHealth Applications

Artificial Intelligence Solutions to Increase Medication Adherence in Patients With Non-communicable Diseases

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Babel, Aditi, Taneja, Richi, Mondello Malvestiti, Franco, Monaco, Alessandro, Donde, Shaantanu·2021·Frontiers in Digital Health

Abstract

Artificial intelligence (AI) tools are increasingly being used within healthcare for various purposes, including helping patients to adhere to drug regimens. The aim of this narrative review was to describe: (1) studies on AI tools that can be used to measure and increase medication adherence in patients with non-communicable diseases (NCDs); (2) the benefits of using AI for these purposes; (3) challenges of the use of AI in healthcare; and (4) priorities for future research. We discuss the current AI technologies, including mobile phone applications, reminder systems, tools for patient empowerment, instruments that can be used in integrated care, and machine learning. The use of AI may be key to understanding the complex interplay of factors that underly medication non-adherence in NCD patients. AI-assisted interventions aiming to improve communication between patients and physicians, monitor drug consumption, empower patients, and ultimately, increase adherence levels may lead to better clinical outcomes and increase the quality of life of NCD patients. However, the use of AI in healthcare is challenged by numerous factors; the characteristics of users can impact the effectiveness of an AI tool, which may lead to further inequalities in healthcare, and there may be concerns that it could depersonalize medicine. The success and widespread use of AI technologies will depend on data storage capacity, processing power, and other infrastructure capacities within healthcare systems. Research is needed to evaluate the effectiveness of AI solutions in different patient groups and establish the barriers to widespread adoption, especially in light of the COVID-19 pandemic, which has led to a rapid increase in the use and development of digital health technologies.

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Crossref · 10.3389/fdgth.2021.669869

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  • AI can prevent medication nonadherence using machine learning algorithms and clinical data, such as patient characteristics, medication history, disease severity, or psychosocial factors.

    “Furthermore, AI can prevent medication nonadherence using machine learning algorithms and clinical data, such as patient characteristics, medication history, disease severity, or psychosocial factors. 69”

    From Artificial Intelligence and Decision-Making in Healthcare: A Thematic Analysis of a Systematic Review of Reviews (2024) · cites this paper as [69]

    The “Machine Learning and Big Data Analytics” section says machine learning has been used to predict nonadherence and can help optimize adherence by combining data sources. The “Patient Characteristics” section identifies psychosocial and drug-related barriers, but the paper does not establish that algorithms using all the listed clinical-data types—including disease severity—prevent nonadherence. Page numbers are unavailable in our copy. (LLM, conf=0.83)

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  • AI can help patients with chronic diseases, such as diabetes, hypertension, or cancer, adhere to their medication regimens by providing reminders, alerts, education, and coaching using mobile phone applications, chatbots, or wearable devices.

    “AI can help patients with chronic diseases, such as diabetes, hypertension, or cancer, to adhere to their medication regimens by providing reminders, alerts, education, and coaching using mobile phone applications, chatbots, or wearable devices.69,70”

    From Artificial Intelligence and Decision-Making in Healthcare: A Thematic Analysis of a Systematic Review of Reviews (2024) · cites this paper as [69]

    Split into 2 atoms — 1 confirmed, 1 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.

    Experimental — accuracy not yet measured

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Authors
Babel, A., Taneja, R., Mondello Malvestiti, F., Monaco, A., & Donde, S.
Affiliations
  • Leeds Teaching Hospitals NHS Trust (GB)
  • Pfizer (India) (IN)
  • HEC Paris (FR)
  • Viatris (US)
Corresponding author
Babel, Aditi
Venue
Frontiers in Digital Health
Published
2021-06-29
Volume
3
Pages
669869-669869
ISSN
2673-253X (ISSN-L)
OpenAlex
W3176812453
Cited by
199
References
72
Citations by year
2026: 40 · 2025: 69 · 2024: 47 · 2023: 37 · 2022: 6
FWCI
5.42
Type
journal article
Language
en
Open access
Locations
  • Frontiers in Digital Health (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, other-oa)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics
  • Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
Keywords
artificial intelligence, medication adherence, non-communicable diseases, mobile health apps, medication reminder system, patient empowerment, integrated care, machine learning, digital health technologies, patient-physician communication, health care disparities, COVID-19 pandemic

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