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Cited by 383

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Report of the First International Consensus on Standardized Nomenclature of Antinuclear Antibody HEp-2 Cell Patterns 2014–2015

Open access
Chan, Edward K. L., Damoiseaux, Jan, Carballo, Orlando Gabriel, Conrad, Karsten, de Melo Cruvinel, Wilson, Francescantonio, Paulo Luiz Carvalho, Fritzler, Marvin J., Garcia-De La Torre, Ignacio, Herold, Manfred, Mimori, Tsuneyo, Satoh, Minoru, von Mühlen, Carlos A., Andrade, Luis E. C.·2015·Frontiers in Immunology

Abstract

During the 12th International Workshop on Autoantibodies and Autoimmunity held in Sao Paulo, Brazil, on August 28, 2014, a full day session was devoted to establishing a consensus on the nomenclature of staining patterns observed in the antinuclear antibody (ANA) indirect immunofluorescence test on HEp-2 cells. The current report summarizes the collective agreements with input from the host Brazilian and international communities that represented research, clinical, and diagnostic service laboratories. Patterns are categorized in three major groups (nuclear, cytoplasmic, and mitotic patterns) and each pattern has been defined and described in detail. The consensus nomenclature and representative patterns are made available online at the international consensus on antinuclear antibody pattern (ICAP) website (www.ANApatterns.org). To facilitate continuous improvement and input, specific comments on ICAP are encouraged and these will be discussed in subsequent ICAP meetings. The ultimate goal with the establishment of the ICAP is to promote harmonization and understanding of autoantibody test nomenclature, as well as interpretation guidelines for ANA testing, thereby optimizing usage in patient care.

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Metadata

Authors
Chan, E. K. L., Damoiseaux, J., Carballo, O. G., Conrad, K., de Melo Cruvinel, W., Francescantonio, P. L. C., Fritzler, M. J., Garcia-De La Torre, I., Herold, M., Mimori, T., Satoh, M., von Mühlen, C. A., & Andrade, L. E. C.
Venue
Frontiers in Immunology
Published
2015-08-20
Volume
6
Pages
412-412
ISSN
1664-3224 (ISSN-L)
OpenAlex
W1530211033
Cited by
383
References
44
FWCI
18.23
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: Report of the First International Consensus on Standardized Nomenclature of Antinuclear Antibody HEp-2 Cell Patterns 2014–2015. https://app.cochat.ai/papers/10.3389/fimmu.2015.00412
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Chan, E. K. L., Damoiseaux, J., Carballo, O. G., Conrad, K., de Melo Cruvinel, W., Francescantonio, P. L. C., Fritzler, M. J., Garcia-De La Torre, I., Herold, M., Mimori, T., Satoh, M., von Mühlen, C. A., & Andrade, L. E. C. (2015). Report of the First International Consensus on Standardized Nomenclature of Antinuclear Antibody HEp-2 Cell Patterns 2014–2015. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2015.00412

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.