The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Toll-like Receptors and Inflammatory Bowel Disease
Open accessAbstract
Inflammatory bowel disease (IBD) is one relapsing and lifelong disease that affects millions of patients worldwide. Increasing evidence has recently highlighted immune-system dysfunction, especially toll-like receptors (TLRs)-mediated innate immune dysfunction, as central players in the pathogenesis of IBD. TLRs and TLR-activated signaling pathways are involved not only in the pathogenesis but also in the efficacy of treatment of IBD. By understanding these molecular mechanisms, we might develop a strategy for relieving the experience of long-lasting suffering of those patients and improving their quality of life. The purpose of this review article is to summarize the potential mechanisms of TLR signaling pathways in IBD and the novel potential therapeutic strategies against IBD.
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Cites
A Toll-like receptor recognizes bacterial DNA
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“TLR9 TLR9 lying on intracellular endosomes recognizes bacterial CpG DNA (57).”
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The Human Intestinal Microbiome in Health and Disease
Lynch, S. V., & Pedersen, O. (2016) · New England Journal of Medicine · doi:10.1056/nejmra1600266 · Cited by 3,637
Symbiotic bacteria direct expression of an intestinal bactericidal lectin
Cash, H. L., Whitham, C. V., Behrendt, C. L., & Hooper, L. V. (2006) · Science · doi:10.1126/science.1127119 · Cited by 1,432
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Therapeutic Potential of Fecal Microbiota Transplantation
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An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells
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The Commensal Microbiota and Enteropathogens in the Pathogenesis of Inflammatory Bowel Diseases
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“org January 2018 | Volume 9 | Article 72 from those of healthy controls (89).”
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Cited by
Ostrowski, J., Goryca, K., Lazowska, I., Rogowska, A., Paziewska, A., Dabrowska, M., Ambrozkiewicz, F., Karczmarski, J., Balabas, A., Kluska, A., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-43699-1 · Cited by 36
Metadata
- Authors
- Lu, Y., Li, X., Liu, S., Zhang, Y., & Zhang, D.
- Venue
- Frontiers in Immunology
- Publisher
- Frontiers Media SA
- Published
- 2018-01-30
- Volume
- 9
- Pages
- 72-72
- ISSN
- 1664-3224 (ISSN-L)
- OpenAlex
- W2793557865
- Cited by
- 341
- References
- 14
- FWCI
- 13.46
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
