The DOI matches its Crossref record; 148 of the 148 references it cites were found in a registry or an index.
Cancer Immunotherapy Based on Natural Killer Cells: Current Progress and New Opportunities
Open accessAbstract
Cancer immunotherapy has been firmly established as a new milestone for cancer therapy, with the development of multiple immune cells as therapeutic tools. Natural killer (NK) cells are innate immune cells endowed with potent cytolytic activity against tumors, and meanwhile act as regulatory cells for the immune system. The effecacy of NK cell-mediated immunotherapy can be enhanced by immune stimulants such as cytokines and antibodies, and adoptive transfer of activated NK cells expanded ex vivo. In addition, NK cells can arm themselves with chimeric antigen receptors (CARs), which may greatly enhance their anti-tumor activity. Most recently, extracellular vesicles (EVs) derived from NK cells show promising anti-tumor effects in preclinical studies. Herein, we carefully review the current progress in these NK cell-based immunotherapeutic strategies (NK cells combined with stimulants, adoptive transfer of NK cells, CAR-NK cells and NK EVs) for the treatment of cancers, and discussed the challenges and opportunities for opening a new horizon for cancer immunotherapy.
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1 retracted
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Oroojalian, F., Beygi, M., Baradaran, B., Mokhtarzadeh, A., & Shahbazi, M. (2021) · Small · doi:10.1002/smll.202006484 · Cited by 528
Ultrasound-Responsive Cavitation Nuclei for Therapy and Drug Delivery
Kooiman, K., Roovers, S., Langeveld, S. A. G., Kleven, R. T., Dewitte, H., O'Reilly, M. A., Escoffre, J.-M., Bouakaz, A., Verweij, M. D., Hynynen, K., et al. (2020) · Ultrasound in Medicine & Biology · doi:10.1016/j.ultrasmedbio.2020.01.002 · Cited by 359
CAR-NK for tumor immunotherapy: Clinical transformation and future prospects
Wang, W., Jiang, J., & Wu, C. (2020) · Cancer Letters · doi:10.1016/j.canlet.2019.11.033 · Cited by 221
Blocking TGF-β Signaling To Enhance The Efficacy Of Immune Checkpoint Inhibitor
Bai, X., Yi, M., Jiao, Y., Chu, Q., & Wu, K. (2019) · OncoTargets and Therapy · doi:10.2147/ott.s224013 · Cited by 153
T-cell agonists in cancer immunotherapy
Choi, Y., Shi, Y., Haymaker, C. L., Naing, A., Ciliberto, G., & Hajjar, J. (2020) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2020-000966 · Cited by 119
Metadata
- Authors
- Hu, W., Wang, G., Huang, D., Sui, M., & Xu, Y.
- Venue
- Frontiers in Immunology
- Publisher
- Frontiers Media SA
- Published
- 2019-05-31
- Volume
- 10
- Pages
- 1205-1205
- ISSN
- 1664-3224 (ISSN-L)
- OpenAlex
- W2946995077
- Cited by
- 398
- References
- 148
- FWCI
- 19.87
- Type
- journal article
- Language
- en
- Open access
- gold
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- Hu, W., Wang, G., Huang, D., Sui, M., & Xu, Y. (2019). Cancer Immunotherapy Based on Natural Killer Cells: Current Progress and New Opportunities. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2019.01205
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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