The DOI matches its Crossref record; 155 of the 155 references it cites were found in a registry or an index.
Interleukins and Ischemic Stroke
Open accessAbstract
Ischemic stroke after cerebral artery occlusion is one of the major causes of chronic disability worldwide. Interleukins (ILs) play a bidirectional role in ischemic stroke through information transmission, activation and regulation of immune cells, mediating the activation, multiplication and differentiation of T and B cells and in the inflammatory reaction. Crosstalk between different ILs in different immune cells also impact the outcome of ischemic stroke. This overview is aimed to roughly discuss the multiple roles of ILs after ischemic stroke. The roles of IL-1, IL-2, IL-4, IL-5, IL-6, IL-8, IL-9, IL-10, IL-12, IL-13, IL-15, IL-16, IL-17, IL-18, IL-19, IL-21, IL-22, IL-23, IL-32, IL-33, IL-34, IL-37, and IL-38 in ischemic stroke were discussed in this review.
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Cites
2 retracted
Armstead, W. M., Hekierski, H., Pastor, P., Yarovoi, S. V., Higazi, A. A., & Cines, D. B. (2018) · Translational Stroke Research · doi:10.1007/s12975-018-0617-z · Cited by 62
RetractedWei, H., Zhen, L., Wang, S., Zhang, Y., Wang, K., Jia, P., Zhang, Y., Wu, Z., Yang, Q., Hou, W., et al. (2021) · Neuroscience · doi:10.1016/j.neuroscience.2021.11.026 · Cited by 19
RetractedImmunological and inflammatory functions of the interleukin-1 family
Dinarello, C. A. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132612 · Cited by 3,466
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
Collison, L. W., Workman, C. J., Kuo, T. T., Boyd, K., Wang, Y., Vignali, K. M., Cross, R., Sehy, D., Blumberg, R. S., & Vignali, D. A. A. (2007) · Nature · doi:10.1038/nature06306 · Cited by 2,066
Interleukin-6 in Biology and Medicine
Akira, S., Taga, T., & Kishimoto, T. (1993) · Advances in Immunology · doi:10.1016/s0065-2776(08)60532-5 · Cited by 1,389
IL-12 family cytokines: immunological playmakers
Vignali, D. A. A., & Kuchroo, V. K. (2012) · Nature Immunology · doi:10.1038/ni.2366 · Cited by 1,297
Campbell, B. C. V., & Khatri, P. (2020) · The Lancet · doi:10.1016/s0140-6736(20)31179-x · Cited by 1,116
Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells
Benakis, C., Brea, D., Caballero, S., Faraco, G., Moore, J., Murphy, M., Sita, G., Racchumi, G., Ling, L., Pamer, E. G., et al. (2016) · Nature Medicine · doi:10.1038/nm.4068 · Cited by 1,114
Interleukin-6, a Major Cytokine in the Central Nervous System
Erta, M., Quintana, A., & Hidalgo, J. (2012) · International Journal of Biological Sciences · doi:10.7150/ijbs.4679 · Cited by 1,087
The IL-23/IL-17 axis in inflammation
Iwakura, Y. (2006) · Journal of Clinical Investigation · doi:10.1172/jci28508 · Cited by 1,046
Cited by
Role of hydrogen sulfide in health and disease
Jin, Y., Yuan, H., Liu, Y., Zhu, Y., Wang, Y., Liang, X., Gao, W., Ren, Z., Ji, X., & Wu, D. (2024) · MedComm · doi:10.1002/mco2.661 · Cited by 54
Wang, N., Xue, Y., Wang, T., Qiu, F., Li, C., Wang, Z., Jiang, J., Lu, Y., Shao, Y., Bai, Z., et al. (2025) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/s12984-025-01679-9 · Cited by 4
Metadata
- Authors
- Zhu, H., Hu, S., Li, Y., Sun, Y., Xiong, X., Hu, X., Chen, J., & Qiu, S.
- Venue
- Frontiers in Immunology
- Publisher
- Frontiers Media SA
- Published
- 2022-01-31
- Volume
- 13
- Pages
- 828447-828447
- ISSN
- 1664-3224 (ISSN-L)
- OpenAlex
- W4213228732
- Cited by
- 363
- References
- 155
- FWCI
- 22.42
- Type
- journal article
- Language
- en
- Open access
- gold
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- Zhu, H., Hu, S., Li, Y., Sun, Y., Xiong, X., Hu, X., Chen, J., & Qiu, S. (2022). Interleukins and Ischemic Stroke. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2022.828447
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.