Synthetic biology of cyanobacteria: unique challenges and opportunities

Berla, Bertram M., Saha, Rajib, Immethun, Cheryl M., Maranas, Costas D., Moon, Tae Seok, Pakrasi, Himadri B.·2013·Frontiers in Microbiology

Cited by (305)

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  2. Attachment of Ferredoxin: NADP+ Oxidoreductase to Phycobilisomes Is Required for Photoheterotrophic Growth of the Cyanobacterium Synechococcus sp. PCC 7002
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  3. Fluctuating pH for efficient photomixotrophic succinate production
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  4. Identification of Four Polyhydroxyalkanoate Structural Genes in Synechocystis cf. salina PCC6909: In silico Evidences
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  5. Optimization of Light and Nutrients Supply to Stabilize Long-Term Industrial Cultivation of Metabolically Engineered Cyanobacteria: A Model-Based Analysis
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  6. Separation of Bioproducts through the Integration of Cyanobacterial Metabolism and Membrane Filtration: Facilitating Cyanobacteria’s Industrial Application
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  7. Optimization of a T7-RNA polymerase system in Synechococcus sp. PCC 7002 mirrors the protein overproduction phenotype from E. coli BL21(DE3)
    Christopher M. Jones, Travis C. Korosh, David R. Nielsen, Brian F. Pfleger · 2021 · Applied Microbiology and Biotechnology
  8. Scalable computation of intracellular metabolite concentrations
    Amir Akbari, Bernhard Ørn Palsson · 2020 · Computers & Chemical Engineering
  9. Construction of Fully Segregated Genomic Libraries in Polyploid Organisms Such as Synechocystis sp. PCC 6803
    Patricia Caicedo-Burbano, Tycho Smit, Hugo Pineda Hernández, Wei Du, Filipe Branco dos Santos · 2020 · ACS Synthetic Biology
  10. Transcriptional terminators allow leak-free chromosomal integration of genetic constructs in cyanobacteria
    Kelly, Ciarán L., Taylor, George M., Satkute, Aiste, Dekker, Linda, Heap, John T. · 2019
  11. Trends in Synthetic Biology in the Bioeconomy of Non-Food-Competing Biofuels
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  12. Earth: Extinguishing anthropogenic risks through harmonization
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  13. Advances in Artificially Designed Antibacterial Active Antimicrobial Peptides
    Ying Guo, Muhammad Haris Raza Farhan, Fei Gan, Xiaohan Yang, Yuxin Li, Lingli Huang, Xu Wang, Guyue Cheng · 2024 · Biotechnology and Bioengineering
  14. Draft Genome Sequence of the Picocyanobacterium Synechococcus sp. Strain GFB01, Isolated from a Freshwater Lagoon in the Brazilian Amazon
    Pedro Ivo Guimarães, Tiago Leão, Aline Grasielle Costa de Melo, Rommel Thiago Jucá Ramos, Artur Silva, Marli Fátima Fiore, Maria Paula Cruz Schneider · 2015 · Genome Announcements
  15. Optimizing cyanobacterial product synthesis: Meeting the challenges
    Tomáš Zavřel, Jan Červený, Henning Knoop, Ralf Steuer · 2016 · Bioengineered
  16. Effects of Activation Energy Diffusion Thermo and Nonlinear Thermal Radiation on Mixed Convection Casson Fluid Flow Through a Vertical Cone with Porous Media in the Presence of Brownian Motion and Thermophoresis
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  17. The Molecular Toolset and Techniques Required to Build Cyanobacterial Cell Factories
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  18. The Sustainable Production of Terpenoids in Cyanobacterial Chassis
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  19. Seven governing principles in biology
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  20. Analysis of the leakage of gene repression by an artificial TetR-regulated promoter in cyanobacteria
    Hsin-Ho Huang, Christian Seeger, U. Helena Danielson, Peter C. Lindblad · 2015 · BMC Research Notes
  21. Engineering Photosynthetic Microbes for Sustainable Bioenergy Production
    Amit Srivastava, Marta Barceló Villalobos, Rakesh Kumar Singh · 2019 · Springer eBooks
  22. Metabolic engineering of cyanobacteria for production of platform chemicals: A synthetic biology approach
    Neha Arora, Damini Jaiswal, Shinjinee Sengupta, Pramod P. Wangikar · 2020 · Elsevier eBooks
  23. Techno-economic and environmental impact analysis of biofuels produced from microalgal biomass
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  24. Protein Phosphorylation Nexus of Cyanobacterial Adaptation and Metabolism
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  25. Designing and Constructing Artificial Small RNAs for Gene Regulation and Carbon Flux Redirection in Photosynthetic Cyanobacteria
    Shubin Li, Tao Sun, Lei Chen, Weiwen Zhang · 2021 · Methods in molecular biology
  26. Utilizing Cyanobacteria in Biophotovoltaics: An Emerging Field in Bioelectrochemistry
    Hans Schneider, Bin Lai, Jens Olaf Krömer · 2022 · Advances in biochemical engineering, biotechnology
  27. Engineering Fibroblast Growth Factor-2 (FGF2) Production in Cyanobacteria
    Bharat Kumar Majhi, Anastasios Melis · 2025 · ACS Synthetic Biology
  28. Activation of the Oxidative Pentose Phosphate Pathway is Critical for Photomixotrophic Growth of a hik33 ‐Deletion Mutant of Synechocystis sp. PCC 6803
    Haitao Ge, Longfa Fang, Xiahe Huang, Jinlong Wang, Weiyang Chen, Yuanya Zhang, Xiaorong Wang, Na Sui, Wu Xu, Qingfang He et al. · 2018 · PROTEOMICS
  29. From the Ocean to the Lab—Assessing Iron Limitation in Cyanobacteria: An Interface Paper
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  30. An approach to nearest neighbor analysis of pigment-protein complexes using chemical cross-linking in combination with mass spectrometry
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  31. Metabolic Rewiring and Cultivation Optimization for Photosynthetic Biofuel Production in Cyanobacteria
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  32. Characterizing Photosynthetic Biofuel Production: Isotopically Non-Stationary 13C Metabolic Flux Analysis on Limonene Producing Synechococcus sp. PCC 7002
    Darrian M. Newman, Cara L. Sake, Alexander J. Metcalf, Fiona K. Davies, Mélissa Cano, Anagha Krishnan, Nanette R. Boyle · 2022 · Frontiers in Energy Research
  33. An overview of electrochemical carbon dioxide conversion strategy
    Svetlana Posokhova, Nikita O. Akhmetov, Anton M. Manakhov, Vikrant B. Wagle · 2026 · Next Energy
  34. Metabolism of microalgae and metabolic engineering for biomaterial applications
    Michele Greque de Morais, Ana Paula Aguiar Cassuriaga, Camila Gonzales Cruz, Luiza Moraes, Jorge Alberto Vieira Costa · 2022 · Elsevier eBooks
  35. Far-red light photoacclimation in a desert Chroococcidiopsis strain with a reduced FaRLiP gene cluster and expression of its chlorophyll f synthase in space-resistant isolates
    Giorgia Di Stefano, Mariano Battistuzzi, Nicoletta La Rocca, Vera M. Selinger, Dennis J. Nürnberg, Daniela Billi · 2024 · Frontiers in Microbiology
  36. Cyanobacterial genome editing toolboxes: recent advancement and future projections for basic and synthetic biology researches
    Sandeep Kumar Singh, Alok Kumar Shrivastava, Ajay Kumar, Vipin Kumar Singh, Deepanker Yadav, Arpan R. Modi, Wenjing Wang, Avinash Kumar Singh, Toolika Singh, Viji Sitther et al. · 2020 · Elsevier eBooks
  37. Advances and Challenges in Sugarcane Biofuel Development
    Abhay Kumar, Vivekanand Tiwari, Pratibha Singh, Sujit Kumar Bishi, Chandan Kumar Gupta, GYAN PRAKASH MISHRA · 2020 · Springer eBooks
  38. Advancements in Biofuel Production
    Javaria Bakhtawar, Hira Arshad, Sobia Faiz, Muhammad Imran Irfan, Hafiz Abdullah Shakir, Muhammad Naeem Khan, Shaukat Ali, Shagufta Saeed, Tahir Mehmood, Marcelo Franco · 2021 · Clean Energy Production Technologies
  39. CyAn: A MATLAB toolbox for image and data analysis of cyanobacteria
    Jian Wei Tay, Jeffrey C. Cameron · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  40. Next‐Generation Cyanobacterial Biocontrol Agents for Crop Fungal Diseases: Molecular Mechanisms, Omics Insights, Applications, and Biosafety Considerations
    Shehzad Ali, Mohammad Shahid, Zaryab Shafi, Mohammed A. Almalki · 2026 · Journal of Basic Microbiology
  41. Cyanobacterial availability for CRISPR-based genome editing: Current and future challenges
    Sandeep Kumar Singh, Ajay Kumar, Mukesh Kumar Yadav, Garima Singh, Punuri Jayasekhar Babu, Zothanpuia Zothanpuia, Liansangmawii Chhakchhuak, Naveen Chandra Joshi, Avinash Chandra Rai, Avinash Kumar Singh et al. · 2021 · Elsevier eBooks
  42. Challenges and Opportunities in Bioprospecting for Sustainable Biofuel Production: Current Status and Future Perspectives
    Sumit Kumar, Dushyant Kumar, Prashant Sharma, Anita Punia · 2022 · International Journal of Current Microbiology and Applied Sciences
  43. “Recent Advances in Algal Biotechnology: Toward the Development of a Sustainable, Algae-Based Bioeconomy”
    Rajkumar Yadav, Avshesh Kumar, Renu Singh · 2022 · REST Journal on Emerging trends in Modelling and Manufacturing
  44. The Role of Modern Biotechnology in the Fight against the Current and the Future Climate Change
    Adugnaw Mekonene Admas, Tileye Feyissa · 2024 · Journal of Advances in Biology & Biotechnology
  45. An automated high-throughput lighting system for screening photosynthetic microorganisms in plate-based formats
    Avery J. C. Noonan, Paula M. N. Cameron, Kalen Dofher, Nannaphat Sukkasam, Tony X. Liu, Lucas Rönn, Tanakarn Monshupanee, Steven Hallam · 2025 · Communications Biology
  46. Impact of dietary supplementation with Synechococcus elongatus PCC 7942 expressing a β-glucosidase from Amazonian soil on the physiology of zebrafish (Danio rerio) fed a soybean meal-rich diet
    Idelette Hernández-López, Raiza dos Santos Azevedo, Mirna Enríquez Reyes, Beatriz Xavier Figueiredo, Isaac dos Santos Flores, Luri Salim Abou Anni, Tony Leandro Rezende da Silveira, Marcelo Borges Tesser, Rodrigo Desessards Jardim, Antônio Sérgio Varela et al. · 2025 · Journal of Applied Phycology
  47. Draft Genome Sequence of Marine Cyanobacterium Synechococcus sp. Strain NKBG042902, Which Harbors a Homogeneous Plasmid Available for Metabolic Engineering
    Toru Honda, Yue Liang, Daichi Arai, Yasuhito Ito, Tomoko Yoshino, Tsuyoshi Tanaka · 2014 · Genome Announcements
  48. Cyanobacteria as a renewable resource for biofuel production
    Deepti Sahasrabuddhe, Annesha Sengupta, Shinjinee Sengupta, Vivek Mishra, Pramod P. Wangikar · 2022 · Elsevier eBooks
  49. Metagenome-Assembled Genomes for “ Candidatus Phormidium sp. Strain AB48” and Co-occurring Microorganisms from an Industrial Photobioreactor Environment
    Avery J. C. Noonan, Yilin Qiu, Brandon Kieft, Sean Formby, Tony Liu, Kalen Dofher, Moritz Koch, Steven Hallam · 2022 · Microbiology Resource Announcements
  50. Sustaining a Mars Colony through Integration of Single-Cell Oil in Biological Life Support Systems
    Krišs Spalviņš, Zane Kušnere, Svetlana Raita · 2023 · Environmental and Climate Technologies
  51. Cyanobacteria as a Photosynthetic Chassis for Metabolic Pathway Engineering with Heterologous Gene Expression
    Walshe, Jessica, Saha, Sushanta Kumar · 2026 · Current Issues in Molecular Biology
  52. Exploring genetic tools for cyanobacteria and their application for biofuels production
    Galyna I. Kufryk · 2022 · Elsevier eBooks
  53. Organic waste types, characteristics, quantities, and potential resource components
    Seema Hodkashia, V. Mubashir Sadiq, Sumit Shekhar · 2025 · Elsevier eBooks
  54. Trends in cyanobacterial Phycobiliproteins - structure, function, and applications: A review
    Indira Mikkili, Sudarsini Borugadda, Ajay Kanaparthy · 2025 · International Journal of Biological Macromolecules
  55. Genetic Modifications in Cyanobacteria: Current Status and Future Prospects
    Kritika Tripathi, Yogesh Mishra · 2026 · IntechOpen eBooks
  56. Active Learning on Protein Language Model Embeddings Accelerates Rubisco Variant Discovery for Desired Traits
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  57. Making-of Synthetic Biology: The European CyanoFactory Research Consortium
    Röbbe Wünschiers · 2015 · Ethics of science and technology assessment/Wissenschaftsethik und Technikfolgenbeurteilung
  58. Biofuels: Present Scenario, Challenges and Future Prospects in India
    Ankit Kushwaha · 2019 · International Journal for Research in Applied Science and Engineering Technology
  59. Synthetic Biology and the Possibilities in Achieving a Plant Demand and Soil Buffer Capacity Adapted Nitrogen (N) Recycling
    Lena Schorr, Janina Schoen, G. Benckiser · 2021 · Environmental science and engineering
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  61. Cyanobacteria as a photosynthetic factory for the production of natural and synthetic compounds
    Yong Xue, Rebekah White, Qingfang He · 2023 · Elsevier eBooks
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    Varsha K. Singh, Niharika Sahu, Sapana Jha, Amit Gupta, Ashish P. Singh, Palak Rana, Jyoti Jaiswal, Neha Kumari, Rajeshwar Prasad Sinha · 2024 · Elsevier eBooks
  64. Fermi calculations enable quick downselection of target genes and process optimization in photosynthetic systems
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  65. Photosynthetic Platform Strain Selection
    Whitney E. Sinclair, Nanette R. Boyle · 2016 · Elsevier eBooks
  66. Introductory Chapter: Preface to Plasmids
    Munazza Gull, Sondos El-Baz · 2019 · IntechOpen eBooks
  67. What We Can Learn from Measuring Metabolic Fluxes in Cyanobacteria
    Xiang Gao, Chao Wu, Michael Cantrell, Mélissa Cano, Jianping Yu, Wei Xiong · 2021
  68. Characterizing Photosynthetic Biofuel Production: Isotopically non-stationary 13 C metabolic flux analysis (INST- 13 CMFA) on limonene producing Synechococcus sp. PCC 7002
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  69. Evaluation and improvement of Synechocystis sp. PCC 6803 tolerance to temperature and development of Synthetic Biology tools
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  70. Development of genetic engineering tools for the cyanobacterium Synechocystis PCC 6803 for advanced biofuel production
    LA Al-Haj · 2014 · UCL Discovery (University College London)
  71. New Energy Crops for Biofuel Production
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  72. A protocell design for bioaccumulation applications
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  73. Tuning for light and more : engineering phototrophy and membrane proteins in Escherichia coli
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  74. Temperature-regulated control of toxic genes in the methylerythritol phosphate pathway of synechococcus sp. PCC 7002 cyanobacteria
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  75. Navigating the fitness landscape using multiallele genome editing
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  76. Synechococcus PCC 7002 growth in anaerobic digestion effluent and off-gas
    Talíta Beyl · 2018 · SUNScholar (Stellenbosch University)
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  78. Biochemical and Structural Studies of Microbial Enzymes for the Biosynthesis of 1,3-butanediol
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  79. Metabolic Network Analysis of Filamentous Cyanobacteria
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  86. Design of an effective sgRNA for CRISPR/Cas9 knock-ins in polyploid Synechocystis sp . PCC 6803
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  87. Current Status of Enzymatic Hydrolysis of Cellulosic Biomass
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  89. Design of an Effective sgRNA for CRISPR/Cas9 Knock-Ins and Full Mutant Segregation in Polyploid Synechocystis sp. PCC 6803
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  95. Additional file 1 of Comparison of alternative integration sites in the chromosome and the native plasmids of the cyanobacterium Synechocystis sp. PCC 6803 in respect to expression efficiency and copy number
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  98. Ingénierie de cyanobactéries pour la photoproduction de terpènes (biocarburants)
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