Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer’s disease

The Amyloid Hypothesis of Alzheimer’s Disease: Progress and Problems on the Road to Therapeutics

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Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy

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Glutamate neurotoxicity and diseases of the nervous system

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Alzheimer's disease: the amyloid cascade hypothesis

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Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

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2016 Alzheimer's disease facts and figures

Alzheimer's Association (2016) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2016.03.001 · Cited by 5,069

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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Alzheimer's Disease Is a Synaptic Failure

Selkoe, D. J. (2002) · Science · doi:10.1126/science.1074069 · Cited by 4,420

Memory decline correlates with increased plasma cytokines in amyloid-beta (1–42) rat model of Alzheimer’s disease

Shallie, O. F., Dallé, E., & Mabandla, M. V. (2020) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2020.107187 · Cited by 20

Effects of N-Terminal Residues on the Assembly of Constrained β-Hairpin Peptides Derived from Aβ

Samdin, T. D., Wierzbicki, M., Kreutzer, A. G., Howitz, W. J., Valenzuela, M., Smith, A., Sahrai, V., Truex, N. L., Klun, M., & Nowick, J. S. (2020) · Journal of the American Chemical Society · doi:10.1021/jacs.0c05186 · Cited by 17

HSF-1 mediated combined ginsenosides ameliorating Alzheimer’s disease like symptoms in Caernorhabditis elegans

Zhi, D., Yang, W., Yue, J., Xu, S., Ma, W., Zhao, C., Wang, X., & Wang, D. (2021) · Nutritional Neuroscience · doi:10.1080/1028415x.2021.1949791 · Cited by 17

Deceleration of the neurodegenerative phenotype in pyroglutamate-Aβ accumulating transgenic mice by oral treatment with the Aβ oligomer eliminating compound RD2

Schemmert, S., Schartmann, E., Honold, D., Zafiu, C., Ziehm, T., Langen, K., Shah, N. J., Kutzsche, J., Willuweit, A., & Willbold, D. (2018) · Neurobiology of Disease · doi:10.1016/j.nbd.2018.10.021 · Cited by 16

The aroylhydrazone INHHQ prevents memory impairment induced by Alzheimer’s-linked amyloid-β oligomers in mice

Falco, A. D., Kincheski, G. C., Atrián‐Blasco, E., Hureau, C., Ferreira, S. T., & Rey, N. A. (2020) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000578 · Cited by 17

Guanosine Neuroprotection of Presynaptic Mitochondrial Calcium Homeostasis in a Mouse Study with Amyloid-β Oligomers

da Silva, J. S., Nonose, Y., Rohden, F., Ferreira, P. C. L., Fontella, F. U., da Rocha, A. S., Brochier, A. W., Apel, R. V., de Lima, T. M., Seminotti, B., et al. (2020) · Molecular Neurobiology · doi:10.1007/s12035-020-02064-4 · Cited by 17

From Hybrids to New Scaffolds: The Latest Medicinal Chemistry Goals in Multi-target Directed Ligands for Alzheimers Disease

Alarcón‐Espósito, J., Mallea, M., & Rodríguez-Lavado, J. (2020) · Current Neuropharmacology · doi:10.2174/1570159x18666200914155951 · Cited by 19

Reduced mitochondria membrane potential and lysosomal acidification are associated with decreased oligomeric Aβ degradation induced by hyperglycemia: A study of mixed glia cultures

Huang, Y., Hsu, S.-M., Shie, F., Shiao, Y., Chao, L.-J., Chen, H., Yao, H.-H., Chien, M. A., Lin, C., & Tsay, H.-J. (2022) · PLoS ONE · doi:10.1371/journal.pone.0260966 · Cited by 17

Amyloid-β Impairs Vesicular Secretion in Neuronal and Astrocyte Peptidergic Transmission

Plá, V., Barranco, N., Pozas, E., & Aguado, F. (2017) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2017.00202 · Cited by 13

CARD9 attenuates Aβ pathology and modifies microglial responses in an Alzheimer’s disease mouse model

Ennerfelt, H. E., Holliday, C., Shapiro, D. A., Zengeler, K. E., Bolte, A. C., Ulland, T. K., & Lukens, J. R. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2303760120 · Cited by 16

A novel apoE-mimetic increases brain apoE levels, reduces Aβ pathology and improves memory when treated before onset of pathology in male mice that express APOE3

Valencia‐Olvera, A. C., Balu, D., Bellur, S., McNally, T. P., Saleh, Y., Pham, D., Ghura, S., York, J. M., Johansson, J. O., LaDu, M. J., et al. (2023) · Alzheimer s Research & Therapy · doi:10.1186/s13195-023-01353-z · Cited by 18

Pharmacological Characterizations of anti-Dementia Memantine Nitrate via Neuroprotection and Vasodilation in Vitro and in Vivo

Mak, S., Liu, Z., Wu, L., Guo, B., Luo, F., Liu, Z., Hu, S., Wang, J., Cui, G., Sun, Y., et al. (2020) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.9b00242 · Cited by 16

Ameliorating amyloid aggregation through osmolytes as a probable therapeutic molecule against Alzheimer's disease and type 2 diabetes

Kumari, A., Somvanshi, P., & Grover, A. (2020) · RSC Advances · doi:10.1039/d0ra00429d · Cited by 16

Move Your Body toward Healthy Aging: Potential Neuroprotective Mechanisms of Irisin in Alzheimer’s Disease

Bellettini‐Santos, T., Batista-Silva, H., Pereira, C. M., Castro, F. C. D. A. Q., Barcelos, R. M., Chiepe, K. C. M. B., Rossoni, J. V., Ambrósio, R. P., da Silva, B. S., Chiarelli-Neto, O., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241512440 · Cited by 16

Amyloid-beta Targeted Therapeutic Approaches for Alzheimer’s Disease: Long Road Ahead

Dai, Y., Lei, C., Zhang, Z., Qi, Y., Lao, K., & Gou, X. (2022) · Current Drug Targets · doi:10.2174/1389450123666220421124030 · Cited by 15

Model scenarios for cell cycle re-entry in Alzheimer's disease

Pandey, N., & Vinod, P. K. U. (2022) · iScience · doi:10.1016/j.isci.2022.104543 · Cited by 15

APC/C-Cdh1-targeted substrates as potential therapies for Alzheimer’s disease

Lapresa, R., Agulla, J., Bolaños, J., & Almeida, Á. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1086540 · Cited by 10

Differential effects of chronic immunosuppression on behavioral, epigenetic, and Alzheimer’s disease-associated markers in 3xTg-AD mice

Kapadia, M., Mian, M. F., Ma, D., Hutton, C. P., Azam, A., Narkaj, K., Cao, C., Brown, B., Michalski, B., Morgan, D., et al. (2021) · Alzheimer's Research & Therapy · doi:10.1186/s13195-020-00745-9 · Cited by 14

Aberrant Synaptic Pruning in CNS Diseases: A Critical Player in HIV-Associated Neurological Dysfunction?

Watson, Z., & Tang, S. (2022) · Cells · doi:10.3390/cells11121943 · Cited by 13

An Essential Role for Alzheimer’s-Linked Amyloid Beta Oligomers in Neurodevelopment: Transient Expression of Multiple Proteoforms during Retina Histogenesis

Bartley, S. C., Proctor, M. T., Xia, H., Ho, E., Kang, D. S., Schuster, K. H., Bicca, M. A., Seckler, H. S., Viola, K. L., Patrie, S. M., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23042208 · Cited by 14

PPAR Gamma Coactivator 1 Beta (PGC-1β) Reduces Mammalian Target of Rapamycin (mTOR) Expression via a SIRT1-Dependent Mechanism in Neurons

Liu, Y., Gao, X., Zhang, Z., Lin, Z., & Zou, Q. (2016) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-016-0425-5 · Cited by 13

Astrocytic Hevin/ SPARCL ‐1 Regulates Cognitive Decline in Pathological and Normal Brain Aging

Cabral‐Miranda, F., Araújo, A. P. B., Medinas, D. B., & Gomes, F. C. A. (2025) · Aging Cell · doi:10.1111/acel.14493 · Cited by 12

A conformation-specific antibody against oligomeric β-amyloid restores neuronal integrity in a mouse model of Alzheimer's disease

He, P., Schulz, P., & Sierks, M. R. (2020) · Journal of Biological Chemistry · doi:10.1074/jbc.ra120.015327 · Cited by 11

Early Effects of the Soluble Amyloid β25-35 Peptide in Rat Cortical Neurons: Modulation of Signal Transduction Mediated by Adenosine and Group I Metabotropic Glutamate Receptors

Castillo, C. A., Ballesteros‐Yáñez, I., León, D., Albasanz, J. L., & Martı́n, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126577 · Cited by 12

Oat Extract Avenanthramide-C Reverses Hippocampal Long-Term Potentiation Decline in Tg2576 Mice

Lee, Y., Wang, M., Son, Y., Yang, E. J., Kang, M.-S., Kim, H., Kim, H., & Jo, J. (2021) · Molecules · doi:10.3390/molecules26206105 · Cited by 12

A Disulfide-Stabilized Aβ that Forms Dimers but Does Not Form Fibrils

Zhang, S., Yoo, S., Snyder, D. T., Katz, B. B., Henrickson, A., Demeler, B., Wysocki, V. H., Kreutzer, A. G., & Nowick, J. S. (2022) · Biochemistry · doi:10.1021/acs.biochem.1c00739 · Cited by 12

Calprotectin influences the aggregation of metal-free and metal-bound amyloid-β by direct interaction

Lee, H. J., Savelieff, M. G., Kang, J., Brophy, M. B., Nakashige, T. G., Lee, S. J. C., Nolan, E. M., & Lim, M. H. (2018) · Metallomics · doi:10.1039/c8mt00091c · Cited by 12

Effect of Global Brain Ischemia on Amyloid Precursor Protein Metabolism and Expression of Amyloid-Degrading Enzymes in Rat Cortex: Role in Pathogenesis of Alzheimer’s Disease

Babušíková, E., Dobrota, D., Turner, A., & Nalivaeva, N. (2021) · Biochemistry (Moscow) · doi:10.1134/s0006297921060067 · Cited by 14

Correction: Plasma microRNAs biomarkers in mild cognitive impairment among patients with type 2 diabetes mellitus

Salama, I. I., Sami, S. M., Elshaarawy, G. A., Mohsen, A., Rasmy, H., Kamel, S. A., Ibrahim, M. H., Ganem, M. M. F., Fouad, W. A., & Raslan, H. M. (2020) · PLoS ONE · doi:10.1371/journal.pone.0243177 · Cited by 11

Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity and memory in mouse models of Alzheimer’s diseasePreprint

Oliveira, M. M., Lourenco, M. V., Longo, F., Kasica, N. P., Yang, W., Ureta, G., Ferreira, D. D. P., Mendonça, P. H. J., Bernales, S., Ma, T., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.10.19.344564 · Cited by 12

Neuronal and Glial α7 Nicotinic Acetylcholine Receptors: Role in Alzheimer’s Disease Pathophysiology

Rennie, K. (2025) · Life · doi:10.3390/life15071032 · Cited by 11

The Therapeutic Potential of Flavonols in Alzheimer's Disease: Inhibiting Amyloid‐β, Oxidative Stress, and Neuroinflammation

Zamanian, M. Y., Khachatryan, L., Heidari, M., Darabi, R., Golmohammadi, M., Al-Aouadi, R. F. A., & Akkol, E. K. (2025) · BioFactors · doi:10.1002/biof.70047 · Cited by 14

Computational modelling of TNFα related pathways regulated by neuroinflammation, oxidative stress and insulin resistance in neurodegeneration

Sasidharakurup, H., & Diwakar, S. (2020) · Applied Network Science · doi:10.1007/s41109-020-00307-w · Cited by 12

Influence of amyloid beta on impulse spiking of isolated hippocampal neurons

Yavorsky, V. A., Rozumna, N. M., & Lukyanetz, E. A. (2023) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2023.1132092 · Cited by 11

Transient sleep apnea results in long-lasting increase in β-amyloid generation and tau hyperphosphorylation

Nagayama, T., Yagishita, S., Shibata, M., Furuno, A., Saito, T., Saido, T. C., Wakatsuki, S., & Araki, T. (2024) · Neuroscience Research · doi:10.1016/j.neures.2024.03.003 · Cited by 10

Effects of amyloid-β on protein SUMOylation and levels of mitochondrial proteins in primary cortical neurons

Soares, E. S., Souza, A. C. G., Zanella, C. A., Carmichael, R. E., Henley, J. M., Wilkinson, K. A., & Cimarosti, H. (2022) · IBRO Neuroscience Reports · doi:10.1016/j.ibneur.2022.01.003 · Cited by 10

Protective Potential of β-Hydroxybutyrate against Glucose-Deprivation-Induced Neurotoxicity Involving the Modulation of Autophagic Flux and the Monomeric Aβ Level in Neuro-2a Cells

Chiang, Y., Nguyen, N. T. K., Hsia, S., Chen, H.-Y., Lin, S., & Lin, C.-I. (2023) · Biomedicines · doi:10.3390/biomedicines11030698 · Cited by 10

7-Pyrrolidinethoxy-4′-Methoxyisoflavone Prevents Amyloid β–Induced Injury by Regulating Histamine H3 Receptor-Mediated cAMP/CREB and AKT/GSK3β Pathways

Wang, L., Fang, J., Jiang, H., Wang, Q., Xue, S.-T., Li, Z., & Liu, R. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00334 · Cited by 10

Identifying N-linked glycan moiety and motifs in the cysteine-rich domain critical for N-glycosylation and intracellular trafficking of SR-AI and MARCO

Tsay, H.-J., Huang, Y., Chen, Y., Lee, Y.-H., Hsu, S.-M., Tsai, K., Yang, C.-N., Huang, F.-L., Shie, F., Lee, L.-C., et al. (2016) · Journal of Biomedical Science · doi:10.1186/s12929-016-0244-5 · Cited by 10

Significant combination of Aβ aggregation inhibitory and neuroprotective properties in silico, in vitro and in vivo by bis(propyl)-cognitin, a multifunctional anti-Alzheimer’s agent

Hu, S., Xian, Y., Fan, Y., Mak, S., Wang, J., Tang, J., Pang, Y., Pi, R., Tsim, K. W. K., Liu, F., et al. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173065 · Cited by 10

Amyloid β-Oligomers Inhibit the Nuclear Ca2+ Signals and the Neuroprotective Gene Expression Induced by Gabazine in Hippocampal Neurons

Lobos, P., Vega-Vásquez, I., Bruna, B., Gleitze, S., Toledo, J. A., Härtel, S., Hidalgo, C., & Paula-Lima, A. C. (2023) · Antioxidants · doi:10.3390/antiox12111972 · Cited by 9

Advances in Gold Nanoparticles for the Diagnosis and Management of Alzheimer’s Disease

Sivamaruthi, B. S., Kesika, P., Sisubalan, N., & Chaiyasut, C. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17091158 · Cited by 9

Therapeutic roles of plants for 15 hypothesised causal bases of Alzheimer’s disease

Tyler, S. E. B., & Tyler, L. D. K. (2022) · Natural Products and Bioprospecting · doi:10.1007/s13659-022-00354-z · Cited by 10

Early Chronic Stress Induced Changes within the Locus Coeruleus in Sporadic Alzheimer’s Disease

Minné, D., Marnewick, J. L., & Engel-Hills, P. C. (2023) · Current Alzheimer Research · doi:10.2174/1567205020666230811092956 · Cited by 10

Kinesin‐1 inhibits the aggregation of amyloid‐β peptide as detected by fluorescence cross‐correlation spectroscopy

Zheng, Y.-P., Tian, S., Peng, X.-L., Yang, J., Fu, Y.-H., Jiao, Y.-Y., Zhao, J., He, J., & Hong, T. (2016) · FEBS Letters · doi:10.1002/1873-3468.12137 · Cited by 9

Vaccines targeting the primary amino acid sequence and conformational epitope of amyloid‐β had distinct effects on neuropathology and cognitive deficits in EAE/AD mice

Yu, X., Zhu, J., Liu, X., Xu, P., Zhang, Y., & Liu, R. (2020) · British Journal of Pharmacology · doi:10.1111/bph.15015 · Cited by 9

Amyloid binding and beyond: a new approach for Alzheimer's disease drug discovery targeting Aβo–PrP C binding and downstream pathways

Grayson, J. D., Baumgartner, M. P., Souza, C. D. S., Dawes, S. J., Idrissi, I. G. E., Louth, J. C., Stimpson, S., Mead, E., Dunbar, C., Wolak, J., et al. (2021) · Chemical Science · doi:10.1039/d0sc04769d · Cited by 10

Specific keratinase derived designer peptides potently inhibit Aβ aggregation resulting in reduced neuronal toxicity and apoptosis

Rajput, R., Linga, B. G., Srivastava, A., Wahi, D., Shrivastava, N., Kundu, B., & Grover, A. (2019) · Biochemical Journal · doi:10.1042/bcj20190183 · Cited by 9

The Aβ aggregation modulator MRZ-99030 prevents and even reverses synaptotoxic effects of Aβ1-42 on LTP even following serial dilution to a 500:1 stoichiometric excess of Aβ1-42, suggesting a beneficial prion-like seeding mechanism

Rammes, G., & Parsons, C. G. (2020) · Neuropharmacology · doi:10.1016/j.neuropharm.2020.108267 · Cited by 10

Regulation of Lipid Dysmetabolism and Neuroinflammation Progression Linked With Alzheimer's Disease Through Modulation of Dgat2

Yadav, A., Ouyang, X., Barkley, M., Watson, J. C., Madhamanchi, K., Kramer, J., Zhang, J., & Melkani, G. C. (2026) · Aging Cell · doi:10.1111/acel.70439 · Cited by 9

Genetic Reduction of the Translational Repressors FMRP and 4E ‐ BP2 Preserves Memory in Mouse Models of Alzheimer's Disease

Ribeiro, F. C., Cozachenco, D., Parkhill, M., Rodrigue, B., Borges, C., Lacaille, J., Nader, K., Felice, F. G. D., Lourenco, M. V., Aguilar‐Valles, A., et al. (2025) · Aging Cell · doi:10.1111/acel.70315 · Cited by 8

Oligomeric and Fibrillar Species of Aβ42 Diversely Affect Human Neural Stem Cells

Bernabeu-Zornoza, A., Coronel, R., Palmer, C., López-Alonso, V., & Liste, I. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22179537 · Cited by 10

Aβ 42 oligomers can seed the fibrillization of Aβ 40 peptides

Wu, Y., Huang, S., Wu, M., Tu, L., Lee, M., & Chan, J. C. C. (2022) · Journal of the Chinese Chemical Society · doi:10.1002/jccs.202200136 · Cited by 7

Quo vadis PGRMC? Grand-Scale Biology in Human Health and Disease

Cahill, M. A. (2022) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2711318 · Cited by 8

Aberrant Expression of GABA-Related Genes in the Hippocampus of 3xTg-AD Model Mice from the Early to End Stages of Alzheimer’s Disease

Mori, H., Yoshino, Y., Iga, J., Ochi, S., Funahashi, Y., Yamazaki, K., Kumon, H., Ozaki, Y., & Ueno, S. (2023) · Journal of Alzheimer s Disease · doi:10.3233/jad-230078 · Cited by 8

A novel peptide derived from vascular endothelial growth factor prevents amyloid beta aggregation and toxicity

Bouvet, P., Gea, P. D., Aimard, M., Chounlamountri, N., Honnorat, J., Delcros, J., Salin, P. A., & Meissirel, C. (2023) · Aging Cell · doi:10.1111/acel.13907 · Cited by 9

Sigma receptors and mitochondria-associated ER membranes are converging therapeutic targets for Alzheimer’s disease

Lotlikar, M. S., Zellmer, J. C., & Bhattacharyya, R. (2025) · Frontiers in Neuroscience · doi:10.3389/fnins.2025.1733659 · Cited by 7

Inhalational Anesthetics Do Not Deteriorate Amyloid-β-Derived Pathophysiology in Alzheimer’s Disease: Investigations on the Molecular, Neuronal, and Behavioral Level

Hofmann, C., Sander, A., Wang, X. X., Buerge, M., Jungwirth, B., Borgstedt, L., Kreuzer, M., Kopp, C., Schorpp, K., Hadian, K., et al. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-201185 · Cited by 7

The AHA/ASA and DSM-V diagnostic criteria for vascular cognitive impairment identify cases with predominant vascular pathology

Folloso, M. C., Villaraza, S. G., Yi-Wen, L., Khong, P., Tanaka, T., Hilal, S., Venketasubramanian, N., & Chen, C. (2024) · International Journal of Stroke · doi:10.1177/17474930241252556 · Cited by 7

Challenges in understanding the structure/activity relationship of Aβ oligomers

Pilkington, A. W., & Legleiter, J. A. (2019) · AIMS Biophysics · doi:10.3934/biophy.2019.1.1 · Cited by 7

Neurodegeneration & imperfect ageing: Technological limitations and challenges?

Sundaria, N., Upadhyay, A., Prasad, A., Prajapati, V. K., Poluri, K. M., & Mishra, A. (2021) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2021.111574 · Cited by 7

Emerging concepts towards a translational framework in Alzheimer’s disease

Cozachenco, D., Zimmer, E. R., & Lourenco, M. V. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105246 · Cited by 7

Research and progress of focused ultrasound in the treatment of Alzheimer’s disease

Ma, X., Li, T., Du, L., & Han, T. (2023) · Frontiers in Neurology · doi:10.3389/fneur.2023.1323386 · Cited by 7

Surface Assay for Specific Detection of Soluble Amyloid Oligomers Utilizing Pronucleon Peptides Instead of Antibodies

Matveeva, E. G., Moll, J. R., Khan, M. M., Thompson, R. B., & Cliff, R. O. (2017) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.6b00381 · Cited by 7

Relationship between efficacy and preferential targeting of soluble Aβ aggregates

Kaplan, J. M., Gibbs, E., Coutts, J. A., Zhao, B., Mackenzie, I. R., Plotkin, S. S., & Cashman, N. R. (2025) · Alzheimer s & Dementia Translational Research & Clinical Interventions · doi:10.1002/trc2.70184 · Cited by 6

Amyloid β Proteoforms Elucidated by Quantitative LC/MS in the 5xFAD Mouse Model of Alzheimer’s Disease

Kandi, S., Cline, E. N., Rivera, B. M., Viola, K. L., Zhu, J., Condello, C., LeDuc, R. D., Klein, W. L., Kelleher, N. L., & Patrie, S. M. (2023) · Journal of Proteome Research · doi:10.1021/acs.jproteome.3c00353 · Cited by 6

Aβ-Targeting Bifunctional Chelators (BFCs) for Potential Therapeutic and PET Imaging Applications

Krasnovskaya, O. O., Kononova, A. О., Erofeev, A. S., Gorelkin, P. V., Majouga, A. G., & Beloglazkina, E. K. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms24010236 · Cited by 6

Distinguishing IDH mutation status in gliomas using FTIR-ATR spectra of peripheral blood plasma indicating clear traces of protein amyloid aggregation

Kino, S., Kanamori, M., Shimoda, Y., Niizuma, K., Endo, H., & Matsuura, Y. (2024) · BMC Cancer · doi:10.1186/s12885-024-11970-y · Cited by 7

Excitation-Energy-Dependent Molecular Beacon Detects Early Stage Neurotoxic Aβ Aggregates in the Presence of Cortical Neurons

Gulácsy, C. E., Meade, R. M., Catici, D. A. M., Soeller, C., Pantoş, G. D., Jones, D. D., Alibhai, D., Jepson, M. A., Valev, V. K., Mason, J. M., et al. (2018) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.8b00322 · Cited by 6

Inhibition of FAM19A5 restores synaptic loss and improves cognitive function in mouse models of Alzheimer’s diseasePreprint

Kim, H., Yoo, S., Kwak, H., Ma, S., Kim, R., Lee, M., Ha, N., Pyo, S., Kwon, S.-G., Cho, E.-H., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.11.22.568357 · Cited by 6

Ultrasensitive Assays Detect Different Conformations of Plasma β Amyloids

Li, C.-Y., Fan, L., Lin, C., Hu, C., & Chiu, M. (2025) · ACS Omega · doi:10.1021/acsomega.4c10879 · Cited by 5

Impaired hippocampal circuit function underlying memory encoding and consolidation precede robust Aβ deposition in a mouse model of alzheimer’s disease

Li, H., Zhao, Z., Fassini, A., Lee, H. K., Green, R. J., & Gomperts, S. N. (2025) · Scientific Reports · doi:10.1038/s41598-025-05653-2 · Cited by 5

Inhibition of amyloid beta oligomer accumulation by NU-9: A unifying mechanism for the treatment of neurodegenerative diseases

Johnson, E. A., Nowar, R., Viola, K. L., Huang, W., Zhou, S., Bicca, M. A., Zhu, W., Kranz, D. L., Klein, W. L., & Silverman, R. B. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2402117122 · Cited by 5

Real-Time Analysis of the Biomolecular Interaction between C1q and Amyloid-β Protein by Dual Polarization Interferometry

Zheng, Y., Ma, L., Wang, Y., Huang, J., Ye, J., & Yang, X. (2025) · Analytical Chemistry · doi:10.1021/acs.analchem.5c02188 · Cited by 5

Recent Advances in Alzheimer’s Disease in Relation to Cholinesterase Inhibitors and NMDA Receptor Antagonists

Nazam, N., Farhana, A., & Shaikh, S. (2021) · Springer eBooks · doi:10.1007/978-981-16-4558-7_8 · Cited by 5

Recent Advancements in the Early Diagnosis and Treatment of Alzheimer's Disease

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Innate Immune Tolerance Regulates Microglia Response to Aβ Oligomers

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Clusterin inhibits Aβ42 aggregation through a “strawberry model” as detected by FRET‐FCS

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The intracerebral injection of Aβ1-42 oligomers does not invariably alter seizure susceptibility in mice

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Beta-Site Amyloid Precursor Protein-Cleaving Enzyme Inhibition Partly Restores Sevoflurane-Induced Deficits on Synaptic Plasticity and Spine Loss

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Destabilization of β‐amyloid aggregates by thrombin derived peptide: plausible role of thrombin in neuroprotection

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Urolithin A reduces amyloid-beta load and improves cognitive deficits uncorrelated with plaque burden in a mouse model of Alzheimer’s diseasePreprint

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Structural Model for Self-Limiting β-strand Arrangement Within an Alzheimer’s Amyloid-β OligomerPreprint

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Natural C20 carotenoids protect dPC12 cells from Aβ-induced cell cycle re-entry, Tau phosphorylation, and Nrf2 activation via the Akt/GSK-3β pathway

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Cognitive dysfunction in type 1 diabetes: role of TREM2 in microglial activation and Aβ pathology

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Rationally Designed Peptoid Inhibitors of Amyloid‐β Oligomerization

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Ruthenium(II)–Arene Complexes with a 2,2′-Bipyridine Ligand as Anti-Aβ Agents

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Oxytocin attenuates microglial activation and restores social and non-social memory in the APP/PS1 mouse model of Alzheimer’s diseasePreprint

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The Design of Metal Complexes to Target the Amyloid‐β Peptide in Alzheimer's Disease

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Multielement concentration analysis of Swiss mice brains on experimental model of Alzheimer's disease induced by β ‐amyloid oligomers

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Promising Prospects for Human Cerebral Organoids to Advance Alzheimer's Disease Research

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Synaptic changes in Alzheimer’s disease and its models

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Reviewed by:

Ferreira, S. T., Lourenco, M. V., Oliveira, M. M., Felice, F. G. D., Kayed, R., Arancio, O., Klein, W. L., & Ferreira, S. T. (2015)