Innate Immune Tolerance in Microglia Does Not Impact on Central Nervous System Prion Disease

Neurotoxic reactive astrocytes are induced by activated microglia

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Microglia Biology: One Century of Evolving Concepts

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Systemic inflammation and disease progression in Alzheimer disease

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Synthetic Mammalian Prions

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Central and Systemic Endotoxin Challenges Exacerbate the Local Inflammatory Response and Increase Neuronal Death during Chronic Neurodegeneration

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Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease.

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Prevalence of lymphoreticular prion protein accumulation in UK tissue samples

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The impact of systemic infection on the progression of neurodegenerative disease

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The Impact of Systemic Inflammation on Alzheimer’s Disease Pathology

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Prevalent abnormal prion protein in human appendixes after bovine spongiform encephalopathy epizootic: large scale survey

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Replicative senescence dictates the emergence of disease-associated microglia and contributes to Aβ pathology

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PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology.

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The lung microbiome regulates brain autoimmunity

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Estimation of Epidemic Size and Incubation Time Based on Age Characteristics of vCJD in the United Kingdom

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Peripheral infection evokes exaggerated sickness behaviour in pre-clinical murine prion disease

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Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration

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Follicular Dendritic Cell Dedifferentiation by Treatment with an Inhibitor of the Lymphotoxin Pathway Dramatically Reduces Scrapie Susceptibility

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Complement 3(+)-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia

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Systemic Inflammation Modulates Fc Receptor Expression on Microglia during Chronic Neurodegeneration

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A neuroprotective role for microglia in prion diseases

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Chronic Systemic Infection Exacerbates Ischemic Brain Damage via a CCL5 (Regulated on Activation, Normal T-Cell Expressed and Secreted)-Mediated Proinflammatory Response in Mice

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Distribution of Experimentally Induced Scrapie Lesions in the Brain

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Microglia Are Critical in Host Defense against Prion Disease

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Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages

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Distribution of Misfolded Prion Protein Seeding Activity Alone Does Not Predict Regions of Neurodegeneration

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GI infections are associated with an increased risk of Parkinson’s disease

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Triggering receptor expressed on myeloid cells-2 is involved in prion-induced microglial activation but does not contribute to prion pathogenesis in mouse brains

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Microglia deficiency accelerates prion disease but does not enhance prion accumulation in the brain

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Memory-Like Responses of Brain Microglia Are Controlled by Developmental State and Pathogen Dose

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Innate immune memory mediates increased susceptibility to Alzheimer’s disease-like pathology in sepsis surviving mice

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Oral Prion Disease Pathogenesis Is Impeded in the Specific Absence of CXCR5-Expressing Dendritic Cells

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Discrimination of Prion Strain Targeting in the Central Nervous System via Reactive Astrocyte Heterogeneity in CD44 Expression

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Systemic Inflammation Accelerates Changes in Microglial and Synaptic Markers in an Experimental Model of Chronic Neurodegeneration

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Prion Protein-Specific Antibodies that Detect Multiple TSE Agents with High Sensitivity

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The Effects of Immune System Modulation on Prion Disease Susceptibility and Pathogenesis

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Trained Innate Immunity by Repeated Low-Dose Lipopolysaccharide Injections Displays Long-Term Neuroprotective Effects

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Prion disease pathogenesis in the absence of the commensal microbiota

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BSE: Epidemiological approaches, trials and tribulations

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Accelerated onset of CNS prion disease in mice co-infected with a gastrointestinal helminth pathogen during the preclinical phase

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Early‐life thermal stress mediates long‐term alterations in hypothalamic microglia

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Postnatal exposure to lipopolysaccharide combined with high-fat diet consumption induces immune tolerance without prevention in spatial working memory impairment

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Microglia deficiency accelerates prion disease but does not enhance prion accumulation in the brainPreprint

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Loss of Homeostatic Microglia Signature in Prion Diseases

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Contributions of Microglia in the Healthy and Injured Brain

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Microglia derived from the axotomized adult rat facial nucleus uptake glutamate and metabolize it to glutamine in vitro

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Naturally-aged microglia exhibit phagocytic dysfunction accompanied by gene expression changes reflective of underlying neurologic disease

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Efficient Strategies for Microglia Replacement in the Central Nervous System

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Microglial Kv1.3 Channels as a Potential Target for Alzheimer's Disease

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