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Huang, S., Patkar, O. L., Schulze, S., Carter‐Cusack, D., Millard, S. M., Ranpura, G. N., Green, E. K., Maxwell, E. L., Kanesarajah, J., Cowin, G., et al. (2025) · Life Science Alliance · doi:10.26508/lsa.202503264 · Cited by 5 · see citing works

Interactions between Cytokines and the Pathogenesis of Prion Diseases: Insights and Implications

Lemos, G. G. M., Moura-do-Nascimento, R., Amaral-do-Nascimento, M., Miceli, A. C., & Vieira, T. C. R. G. (2024) · Brain Sciences · doi:10.3390/brainsci14050413 · Cited by 6 · see citing works

The Role of Glial Cells in Neurobiology and Prion Neuropathology

Hay, A. J. D., Popichak, K. A., Moreno, J. A., & Zabel, M. D. (2024) · Cells · doi:10.3390/cells13100832 · Cited by 5 · see citing works

Downregulation of STAT3 transcription factor reverses synaptotoxic phenotype of reactive astrocytes associated with prion diseases

Kushwaha, R., Molesworth, K., Makarava, N., & Baskakov, I. V. (2025) · Acta Neuropathologica Communications · doi:10.1186/s40478-025-02028-6 · Cited by 5 · see citing works

Interaction between neurons and microglia in healthy and disease states

Nakamura, A., & Shichita, T. (2025) · International Immunology · doi:10.1093/intimm/dxaf057 · Cited by 3 · see citing works

NG2 glia protect against prion neurotoxicity by inhibiting prostaglandin E2 signalingPreprint

Liu, Y.-J., Guo, J.-J., Matoga, M., Korotkova, M., Jakobsson, P.-J., & Aguzzi, A. (2023) · bioRxiv · doi:10.1101/2023.04.04.535590 · Cited by 1 · see citing works

CD11c is not required by microglia to convey neuroprotection after prion infection

Carroll, J. A., Striebel, J. F., Baune, C., Chesebro, B. W., & Race, B. (2023) · PLoS ONE · doi:10.1371/journal.pone.0293301 · Cited by 2 · see citing works

TREM2 supports neuronal protection and microglial reactivity without an effect on misfolded protein deposition in chronic neurodegenerative prion disease

Carpanini, S. M., Bradford, B. M., Alfieri, A., Piccardo, P., Monzón‐Sandoval, J., Brown, D., Boyle, A., Pokrovskaya, A., Mabbott, N. A., Manson, J. C., et al. (2025) · Frontiers in Neuroscience · doi:10.3389/fnins.2025.1525017 · Cited by 1 · see citing works

Adipose-Derived Mesenchymal Stromal Cells Co-Cultured with Primary Mixed Glia to Reduce Prion-Induced Inflammation

Hay, A. J. D., Popichak, K. A., Zabel, M. D., & Moreno, J. A. (2023) · Journal of Visualized Experiments · doi:10.3791/65565 · Cited by 1 · see citing works

Mutation in the rat interleukin 34 gene impacts macrophage development, homeostasis and inflammation in the brain and peripheryPreprint

Huang, S., Patkar, O. L., Schulze, S., Carter‐Cusack, D., Millard, S. M., Ranpura, G. N., Green, E. K., Maxwell, E. L., Kanesarajah, J., Cowin, G., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.30.635395 · Cited by 1 · see citing works

Microglia are not required for normal postnatal brain development and cognitive function in the ratPreprint

Green, E. K., Li, X., Guo, Y., Carter‐Cusack, D., Rojo, R., Lyall, M., Bell, A., Zheng, H., Teenan, O., Till, S. M., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.22.694658 · Cited by 1 · see citing works

Editorial: Prion and prion-like proteins in neurodegenerative diseases

Toni, M., & Eleuteri, S. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.1073218

Single-Cell Transcriptomics Analysis Reveals the Promotion of Mitochondrial Hyperactive Microglial Subpopulations by CSF1R following StrokePreprint

Zou, Q., Wu, H., Zhou, J., Tian, G., Fu, W., Zhao, X., Ward, N., Wang, R., Zhao, R. C., & Wang, J. (2023) · Research Square · doi:10.21203/rs.3.rs-3184652/v1

Friend or Foe: How glial cells interfere with prion-like spreading

Iycattil, A. (2023) · Journal of High School Science · doi:10.64336/001c.84219

APOE genotype differentially modulates prion pathology in a mouse model

Lizińczyk, A. M., Pankiewicz, J. E., Cullina, W. L., Franco, L. A., Sullivan, P. M., & Sadowski, M. J. (2026) · Acta Neuropathologica Communications · doi:10.1186/s40478-025-02207-5

How Glial Cell Dysfunction Fuels Neurodegeneration in Alzheimer’s and Prion Diseases? Emerging Targets for Therapy

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Polymeric lysosome-targeting chimeras for extracellular α-synuclein degradation in Parkinson’s disease

Bhattacharya, A., Almohaimeed, H. M., Aggad, W. S., Almars, ‏. I., Altowaijri, O. M. A., Waggas, H. A., Bauthman, N. M., Mohammedsaleh, Z. M., ALMatrafi, T. A., Saleh, F. M., et al. (2026) · Acta Neuropathologica Communications · doi:10.1186/s40478-026-02335-6

CSF1R-related leukoencephalopathy: experimental models and potential for treatment

Hume, D. A., & Irvine, K. M. (2026) · Disease Models & Mechanisms · doi:10.1242/dmm.052957

Therapeutic strategies in prion disease: current evidence, translational challenges, and emerging directions

Zhu, Y.-X., Bradford, B. M., & Mabbott, N. (2026) · Frontiers in Neuroscience · doi:10.3389/fnins.2026.1924347

Microglia and neuroinflammation: An in‐depth analysis from functional diversity to disease mechanisms

Chen, J., Zhang, W., Song, L., Liao, Y., Zhang, H., Xia, Y., & Cui, D. (2026) · Clinical and Translational Medicine · doi:10.1002/ctm2.70839

Protective role of Galectin‐3 in prion disease through regulation of microglial PrPSc uptake

Makarava, N., Safadi, T., Pandit, N. P., Mychko, O., Bocharova, O., Shevelkin, A., Molesworth, K., Lipinski, M. M., & Baskakov, I. (2026) · bioRxiv · doi:10.1111/bpa.70161 · Cited by 1 · see citing works

Complete Microglia Deficiency Accelerates Prion Disease Without Enhancing CNS Prion AccumulationPreprint

Bradford, B. M., McGuire, L. I., Hume, D. A., Pridans, C., & Mabbott, N. A. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3761455 · Cited by 5 · see citing works

Microglia Are Critical in Host Defense against Prion Disease

Carroll, J. A., Race, B., Williams, K., Striebel, J., & Chesebro, B. (2018) · Journal of Virology · doi:10.1128/jvi.00549-18 · Cited by 94 · see citing works

Neuroinflammation, Microglia, and Cell-Association during Prion Disease

Carroll, J. A., & Chesebro, B. W. (2019) · Viruses · doi:10.3390/v11010065 · Cited by 82 · see citing works

Microglia in Prion Diseases: Angels or Demons?

Peggion, C., Stella, R., Lorenzon, P., Spisni, E., Bertoli, A., & Massimino, M. L. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21207765 · Cited by 18 · see citing works

A neuroprotective role for microglia in prion diseases

Zhu, C., Herrmann, U. S., Falsig, J., Abakumova, I., Nuvolone, M., Schwarz, P., Frauenknecht, K., Rushing, E. J., & Aguzzi, A. (2016) · Journal of Experimental Medicine · doi:10.1084/jem.20151000 · Cited by 134 · see citing works