Understanding the Physiopathology Behind Axial and Radial Diffusivity Changes—What Do We Know?

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Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water

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Toward a quantitative assessment of diffusion anisotropy

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Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia

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Demyelination increases radial diffusivity in corpus callosum of mouse brain

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Hippocampal subfield-specific connectivity findings in major depressive disorder: A 7 Tesla diffusion MRI study

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Plasma lipids are associated with white matter microstructural changes and axonal degeneration

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White matter abnormalities in a patient with visual snow syndrome: New evidence from a diffusion tensor imaging study

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Association of longitudinal cognitive decline with diffusion MRI in gray matter, amyloid, and tau deposition

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The brains of elite soccer players are subject to experience-dependent alterations in white matter connectivity

Yao, Z., Sligte, I. G., Moreau, D., Hsieh, S., Yang, C.-T., Ridderinkhof, K. R., Muggleton, N. G., & Wang, C. (2020) · Cortex · doi:10.1016/j.cortex.2020.07.016 · Cited by 21

A review of multi-modal magnetic resonance imaging studies on perimenopausal brain: a hint towards neural heterogeneity

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Physical activity and the brain myelin content in humans

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First application of 7-T ultra–high field diffusion tensor imaging to detect altered microstructure of thalamic-somatosensory anatomy in trigeminal neuralgia

Rutland, J. W., Huang, K.-H., Gill, C. M., Villavisanis, D. F., Alper, J., Verma, G., Bederson, J. B., Delman, B. N., Shrivastava, R. K., & Balchandani, P. (2019) · Journal of neurosurgery · doi:10.3171/2019.6.jns19541 · Cited by 20

White matter structure in schizophrenia and autism: Abnormal diffusion across the brain in schizophrenia

Haigh, S. M., Eack, S. M., Keller, T. A., Minshew, N. J., & Behrmann, M. (2019) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2019.107233 · Cited by 19

Association Between Proteomic Blood Biomarkers and DTI/NODDI Metrics in Adolescent Football Players: A Pilot Study

Kawata, K., Steinfeldt, J. A., Huibregtse, M. E., Nowak, M. K., Macy, J. T., Kercher, K. A., Rettke, D. J., Shin, A., Chen, Z., Ejima, K., et al. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.581781 · Cited by 19

Altered Structural Brain Networks in Refractory and Nonrefractory Idiopathic Generalized Epilepsy

McKavanagh, A., Kreilkamp, B. A. K., Chen, Y., Denby, C. E., Bracewell, R. M., Das, K., de Bézenac, C. E., Marson, A. G., Taylor, P. N., & Keller, S. S. (2021) · Brain Connectivity · doi:10.1089/brain.2021.0035 · Cited by 19

White matter microstructure and the clinical risk for psychosis: A diffusion tensor imaging study of individuals with basic symptoms and at ultra-high risk

Smigielski, L., Stämpfli, P., Wotruba, D., Buechler, R., Sommer, S., Gerstenberg, M., Theodoridou, A., Walitza, S., Wulf Rössler, A., & Heekeren, K. (2022) · NeuroImage Clinical · doi:10.1016/j.nicl.2022.103067 · Cited by 19

Persistent myelin abnormalities in a third trimester‐equivalent mouse model of fetal alcohol spectrum disorder

Newville, J., Howard, T. A., Chavez, G. J., Valenzuela, C. F., & Cunningham, L. A. (2021) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.14752 · Cited by 18

White matter alterations associated with lifetime and current depression in adolescents: Evidence for cingulum disruptions

Barch, D. M., Hua, X., Kandala, S., Harms, M. P., Sanders, A. F. P., Brady, R. G., Tillman, R., & Luby, J. L. (2022) · Depression and Anxiety · doi:10.1002/da.23294 · Cited by 18

Size at birth predicts later brain volumes

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Multicenter Tract-Based Analysis of Microstructural Lesions within the Alzheimer’s Disease Spectrum: Association with Amyloid Pathology and Diagnostic Usefulness

Teipel, S. J., the DELCODE study group, Kuper-Smith, J. O., Bartels, C., Brosseron, F., Buchmann, M., Büerger, K., Catak, C., Janowitz, D., Dechent, P., et al. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-190446 · Cited by 18

A general role for ventral white matter pathways in morphological processing: Going beyond reading

Yablonski, M., Menashe, B. A., & Ben‐Shachar, M. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.117577 · Cited by 16

Brain white matter microstructure in obese women with binge eating disorder

Estella, N. M., Sanches, L. G., Maranhão, M. F., Hoexter, M. Q., Schmidt, U. H., Campbell, I. C., Amaro, E., & Claudino, A. M. (2020) · European Eating Disorders Review · doi:10.1002/erv.2758 · Cited by 18

Neuroimaging in Leber Hereditary Optic Neuropathy: State-of-the-art and future prospects

Chow-Wing-Bom, H. T., Callaghan, M. F., Wang, J., Wei, S., Dick, F., Yu‐Wai‐Man, P., & Dekker, T. M. (2022) · NeuroImage Clinical · doi:10.1016/j.nicl.2022.103240 · Cited by 18

Comparative overview of multi-shell diffusion MRI models to characterize the microstructure of multiple sclerosis lesions and periplaques

Bulcke, C. V., Stölting, A., Maric, D., Macq, B. M. M., Absinta, M., & Maggi, P. (2024) · NeuroImage Clinical · doi:10.1016/j.nicl.2024.103593 · Cited by 17

Investigating White Matter Tract Microstructural Changes at Six–Twelve Weeks following Mild Traumatic Brain Injury: A Combined Diffusion Tensor Imaging and Neurite Orientation Dispersion and Density Imaging Study

Oehr, L. E., Yang, J. Y., Chen, J., Maller, J. J., Seal, M. L., & Anderson, J. F. I. (2020) · Journal of Neurotrauma · doi:10.1089/neu.2020.7310 · Cited by 18

Effects of simvastatin on white matter integrity in healthy middle‐aged adults

Vogt, N. M., Hunt, J. F. V., Ma, Y., Hulle, C. A. V., Adluru, N., Chappell, R. J., Lazar, K. K., Jacobson, L. E., Austin, B. P., Asthana, S., et al. (2021) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.51421 · Cited by 17

Association between diffusivity measures and language and cognitive-control abilities from early toddler’s age to childhood

Farah, R., Tzafrir, H., & Horowitz‐Kraus, T. (2020) · Brain Structure and Function · doi:10.1007/s00429-020-02062-1 · Cited by 20

Diffusion Tensor Imaging Detects Acute and Subacute Changes in Corpus Callosum in Blast-Induced Traumatic Brain Injury

Venkatasubramanian, P. N., Keni, P., Gastfield, R. D., Li, L., Aksenov, D. P., Sherman, S. A., Bailes, J. E., Sindelar, B., Finan, J. D., Lee, J., et al. (2020) · ASN NEURO · doi:10.1177/1759091420922929 · Cited by 17

Fiber-tract localized diffusion coefficients highlight patterns of white matter disruption induced by proximity to glioma

D’Souza, S., Ormond, D. R., Costabile, J. D., & Thompson, J. A. (2019) · PLoS ONE · doi:10.1371/journal.pone.0225323 · Cited by 16

Ultrahigh field imaging of myelin disease models: Toward specific markers of myelin integrity?

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Cerebrospinal Fluid 7-Ketocholesterol Level is Associated with Amyloid-β42 and White Matter Microstructure in Cognitively Healthy Adults

Iriondo, A., García-Sebastian, M., Arrospide, A., Arriba, M., Aurtenetxe, S., Barandiaran, M., Clerigue, M., Ecay-Torres, M., Estanga, A., Gabilondo, A., et al. (2020) · Journal of Alzheimer's Disease · doi:10.3233/jad-200105 · Cited by 16

Diffusion Tensor Imaging Reveals White Matter Differences in Military Personnel Exposed to Trauma with and without Post-traumatic Stress Disorder

McCunn, P., Richardson, J. A., Jetly, R., & Dunkley, B. T. (2021) · Psychiatry Research · doi:10.1016/j.psychres.2021.113797 · Cited by 16

Longitudinal diffusion tensor magnetic resonance imaging analysis at the cohort level reveals disturbed cortical and callosal microstructure with spared corticospinal tract in the TDP-43G298S ALS mouse model

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Alternative Microstructural Measures to Complement Diffusion Tensor Imaging in Migraine Studies with Standard MRI Acquisition

Planchuelo‐Gómez, Á., García‐Azorín, D., Peral, Á. L. G., de Luis-Garcı́a, R., Rodríguez, M., & Aja‐Fernández, S. (2020) · Brain Sciences · doi:10.3390/brainsci10100711 · Cited by 15

Reduced white matter microstructure in bipolar disorder with and without psychosis

Brown, J. A., Jackson, B. S., Burton, C. R., Hoy, J. E., Sweeney, J. A., Pearlson, G. D., Keshavan, M. S., Keedy, S., Gershon, E. S., Tamminga, C. A., et al. (2021) · Bipolar Disorders · doi:10.1111/bdi.13055 · Cited by 17

Structural connectivity in ventral language pathways characterizes non-verbal autism

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Autologous cellular therapy for cerebral palsy: a randomized, crossover trial

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White matter microstructure predicts individual differences in infant fear (But not anger and sadness)

Planalp, E. M., Dowe, K. N., Alexander, A. L., Goldsmith, H. H., Davidson, R. J., & Dean, D. (2022) · Developmental Science · doi:10.1111/desc.13340 · Cited by 16

White matter microstructure and executive functions in congenital heart disease from childhood to adulthood: A pooled case–control study

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Cerebellar structural, astrocytic, and neuronal abnormalities in the SMNΔ7 mouse model of spinal muscular atrophy

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Improved prediction of glioma‐related aphasia by diffusion MRI metrics, machine learning, and automated fiber bundle segmentation

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Neurophysiological and imaging biomarkers of lower motor neuron dysfunction in motor neuron diseases/amyotrophic lateral sclerosis: IFCN handbook chapter

Lin, C. S.-Y., Howells, J., Rutkove, S. B., Nandedkar, S. D., Neuwirth, C., Noto, Y., Shahrizaila, N., Whittaker, R. G., Bostock, H., Burke, D. J., et al. (2024) · Clinical Neurophysiology · doi:10.1016/j.clinph.2024.03.015 · Cited by 17

A systematic review of MRI studies on the effects of maternal obesity on offspring brain structure and function

Parsaei, M., Hashemi, S. M., Moghaddam, H. S., & Peterson, B. S. (2024) · Journal of Neuroscience Research · doi:10.1002/jnr.25368 · Cited by 15

Exploring white matter microstructure and the impact of antipsychotics in adolescent-onset psychosis

Barth, C., Lonning, V., Gurholt, T. P., Andreassen, O. A., Myhre, A. M., & Agartz, I. (2020) · PLoS ONE · doi:10.1371/journal.pone.0233684 · Cited by 14

Microstructural Predictors of Cognitive Impairment in Cerebral Small Vessel Disease and the Conditions of Their Formation

Добрынина, Л. А., Gadzhieva, Z. S., Витальевна, Ш. К., Kremneva, E. I., Akhmetzyanov, B. M., Kalashnikova, L. А., & Кротенкова, М. В. (2020) · Diagnostics · doi:10.3390/diagnostics10090720 · Cited by 15

Changes in Cerebral Volume and White Matter Integrity in Adults on Hemodialysis and Relationship to Cognitive Function

Richerson, W. T., Umfleet, L. G., Schmit, B. D., & Wolfgram, D. F. (2020) · The Nephron journals/Nephron journals · doi:10.1159/000510614 · Cited by 15

White Matter Microstructural Differences in Youth With Classical Congenital Adrenal Hyperplasia

Cotter, D. L., Azad, A., Cabeen, R. P., Kim, M. S., Geffner, M. E., Sepehrband, F., & Herting, M. M. (2021) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgab520 · Cited by 14

Development of the corpus callosum and cognition after neonatal encephalopathy

Byrne, H. R., Spencer, A. P. C., Geary, G., Jary, S., Thoresen, M., Cowan, F. M., Brooks, J. C. W., & Chakkarapani, E. (2022) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.51696 · Cited by 15

Long-term ovarian hormone deprivation alters functional connectivity, brain neurochemical profile and white matter integrity in the Tg2576 amyloid mouse model of Alzheimer's disease

Kara, F., Belloy, M. E., Voncken, R., Sarwari, Z., Garima, Y., Anckaerts, C., Langbeen, A., Leysen, V., Shah, D., Jacobs, J., et al. (2021) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2021.02.011 · Cited by 15

Progress in Brain Magnetic Resonance Imaging of Individuals with Prader–Willi Syndrome

Huang, Z., & Cai, J. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12031054 · Cited by 14

Characterizing the penumbras of white matter hyperintensities in patients with cerebral small vessel disease

Wang, X., Wang, Y., Gao, D., Zhao, Z., Wang, H., Wang, S., & Liu, S. (2023) · Japanese Journal of Radiology · doi:10.1007/s11604-023-01419-w · Cited by 14

The role of neuronal plasticity in cervical spondylotic myelopathy surgery: functional assessment and prognostic implication

Bonosi, L., Musso, S., Cusimano, L. M., Porzio, M., Giovannini, E. A., Benigno, U. E., Giammalva, G. R., Gerardi, R. M., Brunasso, L., Costanzo, R., et al. (2023) · Neurosurgical Review · doi:10.1007/s10143-023-02062-9 · Cited by 14

White matter microstructural plasticity associated with educational intervention in reading disability

Meisler, S. L., Gabrieli, J. D. E., & Christodoulou, J. A. (2024) · Imaging Neuroscience · doi:10.1162/imag_a_00108 · Cited by 13

Advancements in sarcopenia diagnosis: from imaging techniques to non-radiation assessments

Lavalle, S., Scapaticci, R., Masiello, E., Messina, C., Aliprandi, A., Salerno, V. M., Russo, A., & Pegreffi, F. (2024) · Frontiers in Medical Technology · doi:10.3389/fmedt.2024.1467155 · Cited by 17

Identifying Biomarkers for Remyelination and Recovery in Multiple Sclerosis: A Measure of Progress

Ricigliano, V. A. G., Marenna, S., Borrelli, S., Camera, V., Contentti, E. C., Szejko, N., Bakirtzis, C., Gluščević, S. V., Samadzadeh, S., Hartung, H.-P., et al. (2025) · Biomedicines · doi:10.3390/biomedicines13020357 · Cited by 15

Assessing therapeutic response non-invasively in a neonatal rat model of acute inflammatory white matter injury using high-field MRI

Pierre, W. C., Akakpo, L., Londoño, I., Pouliot, P., Chemtob, S., Lesage, F., & Lodygensky, G. A. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.06.032 · Cited by 14

Structural and Functional Default Mode Network Connectivity and Antipsychotic Treatment Response in Medication-Naïve First Episode Psychosis Patients

Maximo, J. O., Kraguljac, N. V., Rountree, B. G., & Lahti, A. C. (2021) · Schizophrenia Bulletin Open · doi:10.1093/schizbullopen/sgab032 · Cited by 15

A multiparametric MRI study of structural brain damage in dementia with lewy bodies: A comparison with Alzheimer's disease.

Caso, F., Agosta, F., Scamarcia, P. G., Basaia, S., Canu, E., Magnani, G., Volontè, M., & Filippi, M. (2021) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2021.09.025 · Cited by 14

A window into eye movement dysfunction following mTBI: A scoping review of magnetic resonance imaging and eye tracking findings

McDonald, M. A., Tayebi, M., McGeown, J., Kwon, E. E., Holdsworth, S., & Danesh-Meyer, H. (2022) · Brain and Behavior · doi:10.1002/brb3.2714 · Cited by 12

Analysis of white matter tract integrity using diffusion kurtosis imaging reveals the correlation of white matter microstructural abnormalities with cognitive impairment in type 2 diabetes mellitus

Gao, J., Pan, P., Li, J., Tang, M., Yan, X., Zhang, X., Wang, M., Ai, K., Lei, X., Zhang, X., et al. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1327339 · Cited by 13

Age dictates brain functional connectivity and axonal integrity following repetitive mild traumatic brain injuries in mice

Criado‐Marrero, M., Ravi, S., Bhaskar, E., Barroso, D., Pizzi, M. A., Williams, L. N., Wellington, C. L., Febo, M., & Abisambra, J. F. (2024) · NeuroImage · doi:10.1016/j.neuroimage.2024.120764 · Cited by 13

Association between prenatal maternal sleep quality, neonatal uncinate fasciculus white matter, and infant negative emotionality

Nevarez-Brewster, M., Demers, C. H., Deer, L. K., Aran, Ö., Gallop, R., Haase, M. H., Al‐Ali, K., Bagonis, M., Gilmore, J. H., Hoffman, M. C., et al. (2024) · EBioMedicine · doi:10.1016/j.ebiom.2024.105384 · Cited by 14

Resistance training protects the hippocampus and precuneus against atrophy and benefits white matter integrity in older adults with mild cognitive impairment

Ribeiro, I. C., Teixeira, C. V. L., de Rezende, T. J. R., de Campos, B. M., Silva, G. B., Uchida, M. C., Magalhães, T. N. C., Pimentel‐Silva, L. R., Aventurato, Í. K., Gonçalves, B. M. V., et al. (2025) · GeroScience · doi:10.1007/s11357-024-01483-8 · Cited by 16

Autonomic modulation networks in schizophrenia: The relationship between heart rate variability and functional and structural connectivity in the brain

Bengtsson, J., Bodén, R., Olsson, E. M. G., Mårtensson, J., Gingnell, M., & Persson, J. (2020) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2020.111079 · Cited by 13

Uncinate fasciculus and word selection processing in Parkinson's disease

Tella, S. D., Baglio, F., Pelizzari, L., Cabinio, M., Nemni, R., Traficante, D., & Silveri, M. C. (2020) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2020.107504 · Cited by 13

Selective Motor Control is a Clinical Correlate of Brain Motor Tract Impairment in Children with Spastic Bilateral Cerebral Palsy

Vuong, A., Fowler, E., Matsumoto, J. H., Staudt, L. A., Yokota, H., & Joshi, S. H. (2021) · American Journal of Neuroradiology · doi:10.3174/ajnr.a7272 · Cited by 14

Impairment and Plasticity of Language-Related White Matter in Patients With Brain Arteriovenous Malformations

Deng, X., Hu, Y., Zhang, Y., Zhang, D., Wang, S., Cao, Y. B., Li, M., Wang, B., Zong, F., & Zhao, J. (2021) · Stroke · doi:10.1161/strokeaha.121.035506 · Cited by 13

Diffuse white matter abnormality in very preterm infants at term reflects reduced brain network efficiency

Kline, J. E., Illapani, V. S. P., Li, H., He, L., Yuan, W., & Parikh, N. A. (2021) · NeuroImage Clinical · doi:10.1016/j.nicl.2021.102739 · Cited by 15

Gray and White Matter Correlates of Dysphagia in Progressive Supranuclear Palsy

Clark, H. M., Tosakulwong, N., Weigand, S. D., Ali, F., Botha, H., Pham, N. T. T., Schwarz, C. G., Reid, R. I., Senjem, M. L., Jack, C. R., et al. (2021) · Movement Disorders · doi:10.1002/mds.28731 · Cited by 13

Diffusion tensor imaging of white matter microstructure in chronic pain: a tract-based spatial statistics study and a systematic reviewPreprint

Gronemann, D. C., Koch, K., Bantel, C., & Sörös, P. (2020) · medRxiv · doi:10.1101/2020.04.16.20068197 · Cited by 13

Reduced myelin contributes to cognitive impairment in patients with monogenic small vessel disease

Denecke, J., Dewenter, A., Lee, J., Franzmeier, N., Valentim, C., Kopczak, A., Dichgans, M., Pirpamer, L., Gesierich, B. G., Duering, M., et al. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.70127 · Cited by 13

Multimodal Imaging Analysis Reveals Frontal-Associated Networks in Relation to Individual Resilience Strength

Hsieh, S., Yao, Z., & Yang, M. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18031123 · Cited by 13

Topology of diffusion changes in corpus callosum in Alzheimer's disease: An exploratory case-control study

Kumar, S., Luca, A. D., Leemans, A., Saffari, S. E., Hartono, S., Zailan, F. Z., Ng, K. P., & Kandiah, N. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.1005406 · Cited by 12

Corpus callosum organization and its implication to core and co-occurring symptoms of Autism Spectrum Disorder

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