The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Mediators of Physical Activity on Neurocognitive Function: A Review at Multiple Levels of Analysis
Open accessAbstract
Physical activity (PA) is known to maintain and improve neurocognitive health. However, there is still a poor understanding of the mechanisms by which PA exerts its effects on the brain and cognition in humans. Many of the most widely discussed mechanisms of PA are molecular and cellular and arise from animal models. While information about basic cellular and molecular mechanisms is an important foundation from which to build our understanding of how PA promotes cognitive health in humans, there are other pathways that could play a role in this relationship. For example, PA-induced changes to cellular and molecular pathways likely initiate changes to macroscopic properties of the brain and/or to behavior that in turn influence cognition. The present review uses a more macroscopic lens to identify potential brain and behavioral/socioemotional mediators of the association between PA and cognitive function. We first summarize what is known regarding cellular and molecular mechanisms, and then devote the remainder of the review to discussing evidence for brain systems and behavioral/socioemotional pathways by which PA influences cognition. It is our hope that discussing mechanisms at multiple levels of analysis will stimulate the field to examine both brain and behavioral mediators. Doing so is important, as it could lead to a more complete characterization of the processes by which PA influences neurocognitive function, as well as a greater variety of targets for modifying neurocognitive function in clinical contexts.
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ERICKSON, K. I., HILLMAN, C., STILLMAN, C. M., BALLARD, R. M., BLOODGOOD, B., CONROY, D. E., MACKO, R., MARQUEZ, D. X., PETRUZZELLO, S. J., & POWELL, K. E. (2019) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000001936 · Cited by 1,214
Self-citationIntermittent metabolic switching, neuroplasticity and brain health
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Lactate and BDNF: Key Mediators of Exercise Induced Neuroplasticity?
Müller, P., Duderstadt, Y., Lessmann, V., & Müller, N. G. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9041136 · Cited by 241
Dose-Response Matters! - A Perspective on the Exercise Prescription in Exercise-Cognition Research
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Metadata
- Authors
- Stillman, C. M., Cohen, J., Lehman, M. E., & Erickson, K. I.
- Venue
- Frontiers in Human Neuroscience
- Publisher
- Frontiers Media SA
- Published
- 2016-12-08
- Volume
- 10
- Pages
- 626-626
- ISSN
- 1662-5161 (ISSN-L)
- OpenAlex
- W2555331836
- Cited by
- 380
- References
- 30
- FWCI
- 14.60
- Type
- journal article
- Language
- en
- Open access
- gold
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