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Cited by 140Heart Rate Variability and Autonomic ControlAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMind wandering and attention

The DOI matches its Crossref record; 99 of the 99 references it cites were found in a registry or an index.

Cognitive, behavioral, and autonomic correlates of mind wandering and perseverative cognition in major depression

Open access
Ottaviani, Cristina, Shahabi, Leila, Tarvainen, Mika, Cook, Ian, Abrams, Michelle, Shapiro, David·2015·Frontiers in Neuroscience
DOI 10.3389/fnins.2014.00433PMC PMC4283544
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Abstract

Autonomic dysregulation has been hypothesized to play a role in the relationships between psychopathology and cardiovascular risk. An important transdiagnostic factor that has been associated with autonomic dysfunction is perseverative cognition (PC), mainly present in Major Depressive Disorder (MDD) in the form of rumination. As the ability to adaptively let our mind wander without ruminating is critical to mental health, this study aimed to examine the autonomic concomitants of functional vs. dysfunctional intrusive thoughts in MDD. Ambulatory heart rate (HR) and variability (HRV) of 18 MDD subjects and 18 healthy controls were recorded for 24 h. Approximately every 30 min during waking hours subjects reported their ongoing thoughts and moods using electronic diaries. Random regression models were performed. Compared to controls, MDD subjects were more often caught during episodes of PC. In both groups, PC required more effort to be inhibited and interfered more with ongoing activities compared to mind wandering (MW) (ps < 0.0001). This cognitive rigidity was mirrored by autonomic inflexibility, as PC was characterized by lower HRV (p < 0.0001) compared to MW. A worse mood was reported by MDD patients compared to controls, independently of their ongoing cognitive process. Controls, however, showed the highest mood worsening during PC compared to being on task and MW. HRV during rumination correlated with self-reported somatic symptoms on the same day and several dispositional traits. MDD subjects showed lower HRV during sleep, which correlated with hopelessness rumination. Results show that PC is associated with autonomic dysfunctions in both healthy and MDD subjects. Understanding when spontaneous thought is adaptive and when it is not may clarify its role in the etiology of mood disorders, shedding light on the still unexplained association between psychopathology, chronic stress, and risk for health.

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Crossref · 10.3389/fnins.2014.00433

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Figures

Figure 1 Answers to the diary questions “Was the thought interfering with what you were doing?” (interference) and “How much were you trying to suppress the thought?” (suppress) for the periods during which participants (MDD and HC) were engaged in MW or PC.
Figure 1 Answers to the diary questions “Was the thought interfering with what you were doing?” (interference) and “How much were you trying to suppress the thought?” (suppress) for the periods during which participants (MDD and HC) were engaged in MW or PC.CC BY · PubMed Central
Figure 2 Mean ambulatory HRV for the periods during which participants (MDD and HC) were engaged in MW, PC or were focused on task (T), adjusted for age and caffeine consumption.
Figure 2 Mean ambulatory HRV for the periods during which participants (MDD and HC) were engaged in MW, PC or were focused on task (T), adjusted for age and caffeine consumption.CC BY · PubMed Central
Figure 3 Mean mood rating for the periods during which participants (MDD and HC) were engaged in MW, PC or were focused on task (T).
Figure 3 Mean mood rating for the periods during which participants (MDD and HC) were engaged in MW, PC or were focused on task (T).CC BY · PubMed Central

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Cites

Show all 99 references

Research works printed but not linked: 3

  1. Beck, 1996, Manual for the Beck Depression Inventory-II
  2. Hall, 1997, Intrusive thoughts and avoidance behaviors are associated with sleep disturbances in bereavement-related depression, Depress. Anxiety, 6, 106, 10.1002/(SICI)1520-6394(1997)6:3106::AID-DA33.0.CO;2-B · DOI
  3. Spielberger, 1970, STAI Manual

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Metadata

Authors
Ottaviani, C., Shahabi, L., Tarvainen, M., Cook, I., Abrams, M., & Shapiro, D.
Affiliations
  • Fondazione Santa Lucia (IT)
  • University of California, Los Angeles (US)
  • University of Eastern Finland (FI)
Corresponding author
Ottaviani, Cristina
ORCID
Venue
Frontiers in Neuroscience
Publisher
Frontiers Media SA
Published
2015-01-05
Volume
8
Pages
433-433
ISSN
1662-453X (ISSN-L)
DOI
10.3389/fnins.2014.00433
PMC
PMC4283544
OpenAlex
W1993785993
Cited by
140
References
99
Citations by year
2026: 9 · 2025: 13 · 2024: 9 · 2023: 14 · 2022: 15 · 2021: 14 · 2020: 16 · 2019: 12 · 2018: 12 · 2017: 16 · 2016: 8 · 2015: 2
FWCI
9.21
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Frontiers in Neuroscience (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • IRIS Research product catalog (Sapienza University of Rome) (submittedVersion, cc-by-nc-nd)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • eScholarship (California Digital Library) (submittedVersion)
  • eScholarship (California Digital Library) (submittedVersion, cc-by)
Funders
Ministero della Salute (GR2010-2312442, GR-2010)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Mind wandering and attention
Keywords
major depressive disorder, mind wandering, perseverative cognition, rumination, autonomic dysfunction, heart rate variability, heart rate, intrusive thoughts, cognitive effort, mood, somatic symptoms, hopelessness, sleep, chronic stress, cardiovascular risk

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