Understanding and Modeling Metastasis Biology to Improve Therapeutic Strategies for Combating Osteosarcoma Progression

Cites (283)

Items 201–283 of 283

1. Uncovering a key to the process of metastasis in human cancers: a review of critical regulators of anoikis
   Kevin Tan, David Goldstein, Philip John Crowe, Jia‐Lin Yang · 2013 · Journal of Cancer Research and Clinical Oncology
2. Of dogs and men: Comparative biology as a tool for the discovery of novel biomarkers and drug development targets in osteosarcoma
   Kenneth Samora Rankin, Mike Starkey, John Lunec, Craig Gerrand, Sue Murphy, Swethajit Biswas · 2011 · Pediatric Blood & Cancer
3. In vitro and in vivo antitumor effects of the VO-chrysin complex on a new three-dimensional osteosarcoma spheroids model and a xenograft tumor in mice
   Ignácio E. León, Juan F. Cadavid-Vargas, Agustina Resasco, Fabricio Maschi, Miguel Ángel Ayala, Cecilia Carbone, Susana B. Etcheverry · 2016 · JBIC Journal of Biological Inorganic Chemistry
4. NF-kappaB activation within macrophages leads to an anti-tumor phenotype in a mammary tumor lung metastasis model
   Linda Connelly, Whitney Jo Barham, Halina M. Onishko, Lianyi Chen, Taylor P. Sherrill, Tahera Zabuawala, Michael C. Ostrowski, Timothy S. Blackwell, Fiona E. Yull · 2011 · Breast Cancer Research
5. High‐dose ifosfamide in relapsed pediatric osteosarcoma: Therapeutic effects and renal toxicity
   Su Gülsün Berrak, Margaret G. Pearson, Semha Berberoĝlu, İnci Ergürhan İlhan, Norman Jaffe · 2004 · Pediatric Blood & Cancer
6. Targeting Glycoprotein NMB With Antibody‐Drug Conjugate, Glembatumumab Vedotin, for the Treatment of Osteosarcoma
   Michael E. Roth, David M. Barris, Sajida Piperdi, Vicky Fu-Hsuan Kuo, Stephanie Everts, David Geller, Peter J. Houghton, Edward Anders Kolb, Thomas R. Hawthorne, Jonathan Benjamin Gill et al. · 2015 · Pediatric Blood & Cancer
7. ΔNp63 Promotes Pediatric Neuroblastoma and Osteosarcoma by Regulating Tumor Angiogenesis
   Hemant Kumar Bid, Ryan David Roberts, Maren Cam, Anthony N. Audino, Raushan T. Kurmasheva, Jiayuh Lin, Peter J. Houghton, Hakan Çam · 2013 · Cancer Research
8. miR‐134 inhibits osteosarcoma cell invasion and metastasis through targeting MMP 1 and MMP 3 in vitro and in vivo
   Chenglong Chen, Long Zhang, Yurui Jiao, Yi Zhou, Qiaofeng Ge, Pengcui Li, Xiaojuan Sun, Zhi Lv · 2019 · FEBS Letters
9. Extracellular vesicles secreted by highly metastatic clonal variants of osteosarcoma preferentially localize to the lungs and induce metastatic behaviour in poorly metastatic clones
   Rebecca Macklin, Haolu Wang, Dorothy Loo, Sally Martin, Andrew Cumming, Na Cai, Rebecca E. Lane, Natalia Saenz-Ponce, Eleni Topkas, Kerry L. Inder et al. · 2016 · Oncotarget
10. Tim3/Gal9 interactions between T cells and monocytes result in an immunosuppressive feedback loop that inhibits Th1 responses in osteosarcoma patients
    Xiuzhong Li, Yanqing Chen, Xu Liu, Jin Chi Zhang, He Xu, Guodong Teng, Dazhi Yu · 2017 · International Immunopharmacology
11. Global analysis of osteosarcoma lipidomes reveal altered lipid profiles in metastatic versus nonmetastatic cells
    Jahnabi Roy, Payam Dibaeinia, Timothy M. Fan, Saurabh Sinha, Aditi Das · 2018 · Journal of Lipid Research
12. Global Gene Expression Analysis of Canine Osteosarcoma Stem Cells Reveals a Novel Role for COX-2 in Tumour Initiation
    Lisa Y. Pang, Emma L. Gatenby, Ayako Kamida · 2014 · PLoS ONE
13. Modelling the metastatic cascade by in vitro microfluidic platforms
    Timur R. Samatov, M. Yu. Shkurnikov, Svetlana A. Tonevitskaya, Alexander Tonevitsky · 2015 · Progress in Histochemistry and Cytochemistry
14. Chronic bacterial osteomyelitis suppression of tumor growth requires innate immune responses
    Joseph L. Sottnik, Lance U’Ren, Douglas H. Thamm, Stephen J. Withrow, STEVEN W. DOW · 2009 · Cancer Immunology Immunotherapy
15. Upregulation of Glucose-Regulated Protein 78 in Metastatic Cancer Cells Is Necessary for Lung Metastasis Progression
    Lizardo, Michael M., Morrow, James J., Miller, Tyler E., Hong, Ellen S., Ren, Ling, Mendoza, Arnulfo, Halsey, Charles H., Scacheri, Peter C., Helman, Lee J., Khanna, Chand · 2016 · Neoplasia
16. Association of macrophage and lymphocyte infiltration with outcome in canine osteosarcoma
    Sita S. Withers, Katherine A. Skorupski, Daniel S. York, Jin Wook Choi, Kevin Woolard, Renée Laufer Amorim, Ellen E. Sparger, Carlos O. Rodriguez, Stephen J. McSorley, Arta Monir Monjazeb et al. · 2018 · Veterinary and Comparative Oncology
17. The cancer‐related transcription factor RUNX2 modulates expression and secretion of the matricellular protein osteopontin in osteosarcoma cells to promote adhesion to endothelial pulmonary cells and lung metastasis
    Francisco Villanueva, Hector Araya, Pedro Briceño, Nelson Varela, Andres Stevenson, Sofía Jerez, Fabián Tempio, Jonás Chnaiderman, Carola Perez, Milena Villarroel C. et al. · 2019 · Journal of Cellular Physiology
18. Aerosol Gemcitabine: Preclinical Safety and In Vivo Antitumor Activity in Osteosarcoma-Bearing Dogs
    Carlos O. Rodriguez, Torrie A. Crabbs, Dennis W. Wilson · 2009 · Journal of Aerosol Medicine and Pulmonary Drug Delivery
19. Primary metastatic osteosarcoma: results of a prospective study in children given chemotherapy and interleukin-2
    Cristina Meazza, Graziella Cefalo, Maura Massimino, Primo Andrea Daolio, Ugo Pastorino, Paolo Scanagatta, Carlo Morosi, Marta Giorgia Podda, Andrea Ferrari, Monica Terenziani et al. · 2017 · Medical Oncology
20. Metabolomics uncovers a link between inositol metabolism and osteosarcoma metastasis
    Ling Ren, Ellen S. Hong, Arnulfo Mendoza, Sameer H. Issaq, Christine Tran Hoang, Michael M. Lizardo, Amy Kathleen LeBlanc, Chand Khanna · 2017 · Oncotarget
21. Ex vivo screen identifies CDK12 as a metastatic vulnerability in osteosarcoma
    Bayles, Ian, Krajewska, Malgorzata, Pontius, W. Dean, Saiakhova, Alina, Morrow, James J., Bartels, Cynthia, Lu, Jim, Faber, Zachary J., Fedorov, Yuriy, Hong, Ellen S. et al. · 2019 · Journal of Clinical Investigation
22. An orthotopic xenograft model with survival hindlimb amputation allows investigation of the effect of tumor microenvironment on sarcoma metastasis
    Seth D. Goldstein, Masanori Hayashi, Catherine Michelle Albert, Kyle W. Jackson, David Mark Loeb · 2015 · Clinical & Experimental Metastasis
23. Association of α v β 3 integrin expression with the metastatic potential and migratory and chemotactic ability of human osteosarcoma cells
    Xiaoping Duan, Shu-Fang Jia, Zhichao Zhou · 2005 · Clinical & Experimental Metastasis
24. Real-time monitoring of cisplatin cytotoxicity on three-dimensional spheroid tumor cells
    Seong Soo A. An, Ok Won Seo, Jae-Hwa Lee, John Hulme, NamHuk Baek · 2016 · Drug Design Development and Therapy
25. Combining 2D angiogenesis and 3D osteosarcoma microtissues to improve vascularization
    Hassan Chaddad, Sabine Kuchler‐Bopp, Guy Fuhrmann · 2017 · Experimental Cell Research
26. Emerging Technologies for Cancer Research: Towards Personalized Medicine with Microfluidic Platforms and 3D Tumor Models
    Matteo Turetta, Fabio Del Ben, Giulia Brisotto, Eva Biscontin, Michela Bulfoni, Daniela Cesselli, Alfonso Colombatti, G. Scoles, Giuseppe Gigli, Loretta L. del Mercato · 2018 · Current Medicinal Chemistry
27. Improved microfluidic platform for simultaneous multiple drug screening towards personalized treatment
    Oihane Mitxelena‐Iribarren, Jon Zabalo, Sergio Arana, Maite Mujika · 2018 · Biosensors and Bioelectronics
28. Adjuvant chemotherapy in osteosarcoma ? Effects of cisplatinum, BCD, and fibroblast interferon in sequential combination with HD-MTX and adriamycin
    K. Winkler, Gerhard Beron, Rainer Ingo Kotz et al. · 1983 · Journal of Cancer Research and Clinical Oncology
29. Chicken chorioallantoic membrane as a reliable model to evaluate osteosarcoma—an experimental approach using SaOS2 cell line
    Reji Manjunathan, Malathi Ragunathan · 2015 · Biological Procedures Online
30. An Oct4-pRb Axis, Controlled by MiR-335, Integrates Stem Cell Self-Renewal and Cell Cycle Control
    Stefan Schoeftner, Michele Scarola, Elisa Comisso, Claudio Schneider, Roberta Benetti · 2013 · Stem Cells
31. A fluid mechanical analysis of the velocity, adhesion, and destruction of cancer cells in capillaries during metastasis
    Leonard Weiss, Dimeter S. Dimitrov · 1984 · Cell Biophysics
32. The Histone Deacetylase Inhibitor, MS-275 (Entinostat), Downregulates c-FLIP, Sensitizes Osteosarcoma Cells to FasL, and Induces the Regression of Osteosarcoma Lung Metastases
    Krithi Rao‐Bindal, Nadezhda V. Koshkina, John Stewart, Eugenie S. Kleinerman · 2013 · Current Cancer Drug Targets
33. Dynamic analysis of lung metastasis by mouse osteosarcoma LM8: VEGF is a candidate for anti-metastasis therapy
    Takaaki Tanaka, Yoshihiro Yui, Norifumi Naka, Toru Wakamatsu, Kiyoko Yoshioka, Nobuhito Araki, Hideki Yoshikawa, Kazuyuki Itoh · 2012 · Clinical & Experimental Metastasis
34. Osteosarcomagenesis: Modeling Cancer Initiation in the Mouse
    Jones, Kevin B. · 2011 · Sarcoma
35. Dynamic Metabolic Transformation in Tumor Invasion and Metastasis in Mice with LM-8 Osteosarcoma Cell Transplantation
    Yingqi Hua, Yunping Qiu, Aihua Zhao, Xiaoyan Wang, Tianlu Chen, Zhiyu Zhang, Yi Chi, Quan Li, Wei Sun, Guodong Li et al. · 2011 · Journal of Proteome Research
36. Dendritic cells combined with anti-GITR antibody produce antitumor effects in osteosarcoma
    KAWANO, MASANORI, TANAKA, KAZUHIRO, ITONAGA, ICHIRO, IWASAKI, TATSUYA, MIYAZAKI, MASASHI, IKEDA, SHINICHI, TSUMURA, HIROSHI · 2015 · Oncology Reports
37. miR-335 negatively regulates osteosarcoma stem cell-like properties by targeting POU5F1
    Xiaodong Guo, Ling Yu, Zhengpei Zhang · 2017 · Cancer Cell International
38. Exploring the Limits of Cell Adhesion under Shear Stress within Physiological Conditions and beyond on a Chip
    Melanie E. M. Stamp, Anna Martina Jötten, Patrick W. Kudella · 2016 · Diagnostics
39. Activation of unfolded protein response protects osteosarcoma cells from cisplatin-induced apoptosis through NF-κB pathway.
    Mingming Yan, Jiangdong Ni, Deye Song, Muliang Ding, Jun Xing Huang · 2015 · PubMed Central
40. Small-Molecule Procaspase-3 Activation Sensitizes Cancer to Treatment with Diverse Chemotherapeutics
    Rachel C. Botham, Howard S. Roth, Alison P. Book, Patrick J. Roady, Timothy M. Fan, Paul J. Hergenrother · 2016 · ACS Central Science
41. Impact of Hydrogel Elasticity and Adherence on Osteosarcoma Cells and Osteoblasts
    Tongmeng Jiang, Guojie Xu, Xiaoming Chen, Xianyuan Huang, Jinmin Zhao, Li Xiao Zheng · 2019 · Advanced Healthcare Materials
42. Transfection of NF-κB decoy oligodeoxynucleotide suppresses pulmonary metastasis by murine osteosarcoma
    Akinobu Nishimura, Koji Akeda, Takehiro Matsubara · 2010 · Cancer Gene Therapy
43. Targeting p21-activated kinase 1 inhibits growth and metastasis via Raf1/MEK1/ERK signaling in esophageal squamous cell carcinoma cells
    Liang Chen, Shuning Bi, Jiuzhou Hou · 2019 · Cell Communication and Signaling
44. Zoledronic acid inhibits vasculogenic mimicry in murine osteosarcoma cell line in vitro
    Dehao Fu, HE Xian-feng, Shuhua Yang, Weihua Xu, Tao Lin, Xiaobo Feng · 2011 · BMC Musculoskeletal Disorders
45. Outcomes for pediatric patients with osteosarcoma treated with palliative radiotherapy
    Emily Chen, Christopher H. Yoo, Paulina M. Gutkin, David J. Merriott, Raffi S. Avedian, Robert J. Steffner, Sheri L. Spunt, Allison K. Pribnow, Lynn Million, Sarah S. Donaldson et al. · 2019 · Pediatric Blood & Cancer
46. Targeted delivery of CCR2 antagonist to activated pulmonary endothelium prevents metastasis
    Marko Roblek, Manuela Călin, Martin Schlesinger, Daniela L Stan, Reiner Zeisig, Maya Simionescu, Gerd Bendas, Lubor Borsig · 2015 · Journal of Controlled Release
47. TIMP3 regulates osteosarcoma cell migration, invasion, and chemotherapeutic resistances
    Xiuguo Han, Yan Li, Huimin Mo, Kang Li, Du Lin, Changqing Zhao, Jie Zhao, Tingting Tang · 2016 · Tumor Biology
48. Tissue factor associates with survival and regulates tumour progression in osteosarcoma
    Chris Tieken, Michiel C. Verboom, Wolfram Ruf · 2016 · Thrombosis and Haemostasis
49. The downregulation of miR-125a-5p functions as a tumor suppressor by directly targeting MMP-11 in osteosarcoma
    Waresijiang Niyazi, Jungang Sun, Rewuti Abuduaini · 2016 · Molecular Medicine Reports
50. Apoptosis Resistance and PKC Signaling: Distinguishing Features of High and Low Metastatic Cells
    Sung-Hyeok Hong, Ling Ren, Arnulfo Mendoza, Ananth S. Eleswarapu, Chand Khanna · 2012 · Neoplasia
51. The Role of VE-cadherin in Osteosarcoma Cells
    Lizhi Zhang, Jiong Mei, Zhikang Qian · 2009 · Pathology & Oncology Research
52. Therapeutic inhibition of breast cancer bone metastasis progression and lung colonization: breaking the vicious cycle by targeting α5β1 integrin
    Hongren Yao, Donna M. Veine, Donna L. Livant · 2016 · Breast Cancer Research and Treatment
53. ATF6α Activation Enhances Survival against Chemotherapy and Serves as a Prognostic Indicator in Osteosarcoma
    Suma Yarapureddy, Jazmine Abril, Janet A. Foote, Saravana Kumar, Omar Asad, Veena Sharath, Janine Faraj, Dustin Daniel, Paul S. Dickman, Andrea White‐Collins et al. · 2019 · Neoplasia
54. The Dominant Role of IL-8 as an Angiogenic Driver in a Three-Dimensional Physiological Tumor Construct for Drug Testing
    Pamela H.S. Tan, Su Shin Chia, Siew Lok Toh · 2013 · Tissue Engineering Part A
55. mTOR Inhibition Mitigates Enhanced mRNA Translation Associated with the Metastatic Phenotype of Osteosarcoma Cells <i>In Vivo</i>
    Morrow, James J., Mendoza, Arnulfo, Koyen, Allyson, Lizardo, Michael M., Ren, Ling, Waybright, Timothy J., Hansen, Ryan J., Gustafson, Daniel L., Zhou, Ming, Fan, Timothy M. et al. · 2016 · Clinical Cancer Research
56. An Improved In Vivo Methodology to Visualise Tumour Induced Changes in Vasculature Using the Chick Chorionic Allantoic Membrane Assay
    Naşide Mangır, Ahtasham Raza, John W. Haycock, Christopher Reginald Chapple, Sheila MacNeil · 2018 · In Vivo
57. Collagen I regulates matrix metalloproteinase‐2 activation in osteosarcoma cells independent of S100A4
    Renate Elenjord, Jasmine B. Allen, Harald Thidemann Johansen, Hanne Kildalsen, Gunbjørg Svineng, Gunhild Mari Mælandsmo, Thrina Loennechen, Jan‐Olof Winberg · 2009 · FEBS Journal
58. Mapping of the functional microcirculation in vital organs using contrast-enhanced in vivo video microscopy
    Hemanth J. Varghese, Lisa T. MacKenzie, Alan C. Groom · 2004 · American Journal of Physiology-Heart and Circulatory Physiology
59. Targeting HSP70 and GRP78 in canine osteosarcoma cells in combination with doxorubicin chemotherapy
    Jonathan Asling, Jodi A. Morrison, Anthony J. Mutsaers · 2016 · Cell Stress and Chaperones
60. ΔNp63 mediates cellular survival and metastasis in canine osteosarcoma
    Maren Cam, Heather L. Gardner, Ryan David Roberts, Joelle M. Fenger, Denis C. Guttridge D, Cheryl A. London, Hakan Çam · 2016 · Oncotarget
61. mTORC1 Maintains the Tumorigenicity of SSEA-4+ High-Grade Osteosarcoma
    Wu Zhang, Menglei Ding, Jia-Nian Zhang, Jian-Ru Qiu, Yuhui Shen, Xiao-Yi Ding, Lianfu Deng, Weibin Zhang, Jiang Zhu · 2015 · Scientific Reports
62. The effect of Zhangfei/CREBZF on cell growth, differentiation, apoptosis, migration, and the unfolded protein response in several canine osteosarcoma cell lines
    Rui Zhang, Douglas H. Thamm, Vikram Misra · 2015 · BMC Veterinary Research
63. Prostaglandin E2 receptor 4 mediates renal cell carcinoma intravasation and metastasis
    Yushan Zhang, Hamsa Thayele Purayil, Joseph B. Black, Francis Fetto, Lauren D. Lynch, Jude Masannat, Yehia Daaka · 2017 · Cancer Letters
64. Protein profiling of osteosarcoma tissue and soft callus unveils activation of the unfolded protein response pathway
    Parunya Chaiyawat, Patsadakorn Sungngam, Pimpisa Teeyakasem et al. · 2019 · International Journal of Oncology
65. Methods for co-culturing tumour and endothelial cells: systems and their applications
    Mallory van Moorst, Crispin R. Dass · 2011 · Journal of Pharmacy and Pharmacology
66. Chorioallantoic Membrane Microtumor Model to Study the Mechanisms of Tumor Angiogenesis, Vascular Permeability, and Tumor Cell Intravasation
    Elena I. Deryugina · 2016 · Methods in molecular biology
67. Fibroblast activation protein in osteosarcoma cells promotes angiogenesis via AKT and ERK signaling pathways
    Chao Zeng, Ming Wen, Xiaomei Liu · 2018 · Oncology Letters
68. Practical Considerations in Studying Metastatic Lung Colonization in Osteosarcoma Using the Pulmonary Metastasis Assay
    Lizardo, Michael M., Sorensen, Poul H. · 2018 · Journal of Visualized Experiments
69. THE TREATMENT OF SARCOMA OF THE LONG BONES*
    WILLIAM B. COLBY · 1933 · Annals of Surgery
70. The urokinase receptor-derived cyclic peptide [SRSRY] suppresses neovascularization and intravasation of osteosarcoma and chondrosarcoma cells
    Vincenzo Ingangi, Katia Bifulco, Ali Munaim Yousif et al. · 2016 · Oncotarget
71. Pericellular Matrix Formation Alters the Efficiency of Intracellular Uptake of Oligonucleotides in Osteosarcoma Cells
    Yoshitaka Suzuki, Yoshihiro Nishida, Takahiro Naruse · 2008 · Journal of Surgical Research
72. Anoikis induction and metastasis suppression by a new integrin αvβ3 inhibitor in human melanoma cell line M21
    Yongci Zhang, Ming Yang, Qing Ji · 2010 · Investigational New Drugs
73. Activation of unfolded protein response protects osteosarcoma cells from cisplatin-induced apoptosis through NF-kappaB pathway.
    Deye, Huang, Jun · 2015
74. Development of a shear stress-free microfluidic gradient generator capable of quantitatively analyzing single-cell morphology
    David Baião Barata, Giulia Spennati, Cristina O. Correia, Nelson Ribeiro, Björn Harink, Clemens van Blitterswijk, Pamela Habibović, Sabine van Rijt · 2017 · Biomedical Microdevices
75. High expression of ID1 facilitates metastasis in human osteosarcoma by regulating the sensitivity of anoikis via PI3K/AKT depended suppression of the intrinsic apoptotic signaling pathway.
    Guosheng Zhao, Qiao Zhang, Ya Cao, Yang Wang, Yangfan Lv, Zhaosi Zhang, Yuan Zhang, Qiu‐Lin Tan, Yu Chang, Zhengxue Quan et al. · 2019 · PubMed Central
76. Combinatorial Discovery of Defined Substrates That Promote a Stem Cell State in Malignant Melanoma
    Douglas Zhang, Junmin Lee, Michael B. Sun, Yi Pei, James L. Chu, Martha Ulbrick Gillette, Timothy M. Fan, Kristopher Alan Kilian · 2017 · ACS Central Science
77. Systematic Evaluation of Drug-Loaded Hydrogels for Application in Osteosarcoma Treatment
    Seyit Ali Gümüştaş, Mehmet İşyar, Savaş Topuk · 2016 · Current Pharmaceutical Biotechnology
78. Thrombin is Present in the Lungs of Patients with Primary Extremity Osteosarcoma and Pulmonary Metastases
    Norma A. Hernández-Rodríguez, E Correa, Rene Javier Sotelo · 2002 · The International Journal of Biological Markers
79. Growth of osteosarcoma cells in a three-dimensional bone-like matrix alters their susceptibility to adeno-associated virus
    Sangeeta Dey, Leila N. Laredj, Katarina Damjanovic · 2014 · Journal of General Virology
80. RANKL inhibitors for osteosarcoma treatment: hope and caution
    Eva María Trinidad, Eva González‐Suárez · 2016 · Annals of Translational Medicine
81. Chemotherapy Regimens for Patients with Newly Diagnosed Malignant Bone Tumors
    Ryan David Roberts, Mary Frances Wedekind, Bhuvana A. Setty · 2015 · Pediatric oncology
82. Automated quantitative image analysis for ex vivo metastasis assays reveals differing lung composition requirements for metastasis suppression by KISS1
    Eric D. Young, Kyle B. Strom, Ashley F. Tsue, Joseph L. Usset, Seth MacPherson, John T. McGuire, Danny R. Welch · 2018 · Clinical & Experimental Metastasis
83. Author response: Flura-seq identifies organ-specific metabolic adaptations during early metastatic colonization
    Harihar Basnet, Lin Hai Tian, Karuna Ganesh · 2019