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Cited by 128Plant Stress Responses and ToleranceRedox biology and oxidative stressNitric Oxide and Endothelin Effects

Protein tyrosine nitration in higher plants grown under natural and stress conditions

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Corpas, Francisco J., Palma, José M., del Río, Luis A., Barroso, Juan B.·2013·Frontiers in Plant Science
DOI 10.3389/fpls.2013.00029PMC PMC3580390
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Abstract

Protein tyrosine nitration is a post-translational modification (PTM) mediated by reactive nitrogen species (RNS) that is linked to nitro-oxidative damages in plant cells. During the last decade, the identification of proteins undergoing this PTM under adverse environmental conditions has increased. However, there is also a basal endogenous nitration which seems to have a regulatory function. The technological advances in proteome analysis have allowed identifying these modified proteins and have shown that the number and identity of the nitrated proteins change among plant species, analysed organs and growing/culture conditions. In this work, the current knowledge of protein tyrosine nitration in higher plants under different situations is reviewed.

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  • 3-NT has been primarily used for determination of protein nitration and nitrosative stress in clinical settings.

    “3-NT, the stable endproduct of peroxynitrite-mediated oxidation formed via nitration of free or protein-bound tyrosine, has been primarily used for the determination of protein nitration and nitrosative stress in clinical settings [186,187].”

    From Protein oxidation - Formation mechanisms, detection and relevance as biomarkers in human diseases (2021) · cites this paper as [186]

    The section on in vivo detection reports using antibodies against 3-nitrotyrosine to detect protein nitration in plants. The Introduction also describes nitrotyrosine as a footprint of peroxynitrite. The paper does not establish that 3-NT has been used primarily in clinical settings; its examples concern plants. (LLM, conf=0.82)

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  1. Abello N. Kerstjens H. A. Postma D. S. Bischoff R. (2009). Protein tyrosine nitration: selectivity, physicochemical and biological consequences, denitration, and proteomics methods for the identification of tyrosine-nitrated proteins. J. Proteome Res. 8, 3222– 3238 10.1021/pr900039c 19415921 · DOI · Paper page
  2. Airaki M. Leterrier M. Mateos R. M. Valderrama R. Chaki M. Barroso J. B. (2012). Metabolism of reactive oxygen species and reactive nitrogen species in pepper (Capsicum annuum L.) plants under low temperature stress. Plant Cell Environ. 35, 281– 295 10.1111/j.1365-3040.2011.02310.x 21414013 · DOI
  3. Álvarez C. Lozano-Juste J. Romero L. C. García I. Gotor C. León J. (2011). Inhibition of Arabidopsis O-acetylserine(thiol)lyase A1 by tyrosine nitration. J. Biol. Chem. 86, 578– 586 10.1074/jbc.M110.147678 21047785 PMC3013017 · DOI
  4. Arasimowicz-Jelonek M. Floryszak-Wieczorek J. (2011). Understanding the fate of peroxynitrite in plant cells–from physiology to pathophysiology. Phytochemistry 72, 681– 688 10.1016/j.phytochem.2011.02.025 21429536 · DOI
  5. Begara-Morales J. C. Chaki M. Sánchez-Calvo B. Mata-Pérez C. Leterrier M. Valderrama R. (2013). Protein tyrosine nitration in pea roots during development and senescence. J. Exp. Bot. 64, [Epub ahead of print]. 10.1093/jxb/ert006 23362300 PMC3580824 · DOI
  6. Cecconi D. Orzetti S. Vandelle E. Rinalducci S. Zolla L. Delledonne M. (2009). Protein nitration during defense response in Arabidopsis thaliana. Electrophoresis 30, 2460– 2468 10.1002/elps.200800826 19598157 · DOI
  7. Cellini A. Corpas F. J. Barroso J. B. Masia A. (2011). Nitric oxide content is associated with tolerance to bicarbonate-induced chlorosis in micropropagated Prunus explants. J. Plant Physiol. 168, 1543– 1549 10.1016/j.jplph.2011.02.008 21507506 · DOI
  8. Chaki M. Carreras A. López-Jaramillo J. Begara-Morales J. C. Sánchez-Calvo B. Valderrama R. (2013). Tyrosine nitration provokes inhibition of carbonic anhydrase (β-CA) activity under high temperature stress. Nitric Oxide 29C, 30– 33 10.1016/j.niox.2012.12.003 23266784 · DOI
  9. Chaki M. Valderrama R. Fernández-Ocaña A. M. Carreras A. Gómez-Rodríguez M. V. López-Jaramillo J. (2011). High temperature triggers the metabolism of S-nitrosothiols in sunflower mediating a process of nitrosative stress which provokes the inhibition of ferredoxin-NADP reductase by tyrosine nitration. Plant Cell Environ. 34, 1803– 1818 10.1111/j.1365-3040.2011.02376.x 21676000 · DOI
  10. Chaki M. Valderrama R. Fernández-Ocaña A. M. Carreras A. López-Jaramillo J. Luque F. (2009a). Protein targets of tyrosine nitration in sunflower (Helianthus annuus L.) hypocotyls. J. Exp. Bot. 60, 4221– 4234 10.1093/jxb/erp263 19717529 · DOI
  11. Chaki M. Fernández-Ocaña A. M. Valderrama R. Carreras A. Esteban F. J. Luque F. (2009b). Involvement of reactive nitrogen and oxygen species (RNS and ROS) in sunflower-mildew interaction. Plant Cell Physiol. 50, 265– 279 10.1093/pcp/pcn196 19112080 · DOI
  12. Clark D. Durner J. Navarre D. A. Klessig D. F. (2000). Nitric oxide inhibition of tobacco catalase and ascorbate peroxidase. Mol. Plant Microbe Interact. 13, 1380– 1384 10.1094/MPMI.2000.13.12.1380 11106031 · DOI
  13. Corpas F. J. Chaki M. Fernández-Ocaña A. Valderrama R. Palma J. M. Begara-Morales J. C. (2008). Metabolism of reactive nitrogen species in pea plants under abiotic stress conditions. Plant Cell Physiol. 49, 1711– 1722 10.1093/pcp/pcn144 18801763 · DOI
  14. Corpas F. J. Chaki M. Leterrier M. Barroso J. B. (2009). Protein tyrosine nitration: a new challenge in plants. Plant Signal. Behav. 4, 1– 4 10.4161/psb.4.10.9466 19826215 PMC2801353 · DOI
  15. Corpas F. J. del Río L. A. Barroso J. B. (2007). Need of biomarkers of nitrosative stress in plants. Trends Plant Sci. 12, 436– 438 10.1016/j.tplants.2007.08.013 17826297 · DOI
  16. Dekker F. Abello N. Wisastra R. Bischoff R. (2012). Enrichment and detection of tyrosine-nitrated proteins. Curr. Protoc. Protein Sci. 69, 14.13.1– 14.13.19 10.1002/0471140864.ps1413s69 22851496 · DOI
  17. Galetskiy D. Lohscheider J. N. Kononikhin A. S. Popov I. A. Nikolaev E. N. Adamska I. (2011). Phosphorylation and nitration levels of photosynthetic proteins are conversely regulated by light stress. Plant Mol. Biol. 77, 461– 473 10.1007/s11103-011-9824-7 21901528 · DOI
  18. Gow A. J. Farkouh C. R. Munson D. A. Posencheg M. A. Ischiropoulos H. (2004). Biological significance of nitric oxide-mediated protein modifications. Am. J. Physiol. Lung Cell Mol. Physiol. 287, L262– L268 10.1152/ajplung.00295.2003 15246980 · DOI
  19. Greenacre S. A. Ischiropoulos H. (2001). Tyrosine nitration: localisation, quantification, consequences for protein function and signal transduction. Free Radic. Res. 34, 541– 581 11697033
  20. Ischiropoulos H. (2003). Biological selectivity and functional aspects of protein tyrosine nitration. Biochem. Biophys. Res. Commun. 305, 776– 783 10.1016/S0006-291X(03)00814-3 12763060 · DOI · Paper page
  21. Jovanović A. M. Durst S. Nick P. (2010). Plant cell division is specifically affected by nitrotyrosine. J. Exp. Bot. 61, 901– 909 10.1093/jxb/erp369 20018903 PMC2814120 · DOI
  22. Leterrier M. Airaki M. Palma J. M. Chaki M. Barroso J. B. Corpas F. J. (2012). Arsenic triggers the nitric oxide (NO) and S-nitrosoglutathione (GSNO) metabolism in Arabidopsis. Environ. Pollut. 166, 136– 143 10.1016/j.envpol.2012.03.012 22504427 · DOI
  23. Lozano-Juste J. Colom-Moreno R. León J. (2011). In vivo protein tyrosine nitration in Arabidopsis thaliana. J. Exp. Bot. 62, 3501– 3517 10.1093/jxb/err042 21378116 PMC3130175 · DOI
  24. Melo P. M. Silva L. S. Ribeiro I. Seabra A. R. Carvalho H. G. (2011). Glutamine synthetase is a molecular target of nitric oxide in root nodules of Medicago truncatula and is regulated by tyrosine nitration. Plant Physiol. 157, 1505– 1517 10.1104/pp.111.186056 21914816 PMC3252174 · DOI
  25. Morot-Gaudry-Talarmain Y. Rockel P. Moureaux T. Quilleré I. Leydecker M. T. Kaiser W. M. (2002). Nitrite accumulation and nitric oxide emission in relation to cellular signaling in nitrite reductase antisense tobacco. Planta 215, 708– 715 10.1007/s00425-002-0816-3 12244435 · DOI
  26. Radi R. (2004). Nitric oxide, oxidants, and protein tyrosine nitration. Proc. Natl. Acad. Sci. U.S.A. 101, 4003– 4008 10.1073/pnas.0307446101 15020765 PMC384685 · DOI
  27. Saito S. Yamamoto-Katou A. Yoshioka H. Doke N. Kawakita K. (2006). Peroxynitrite generation and tyrosine nitration in defense responses in tobacco BY-2 cells. Plant Cell Physiol. 47, 689– 697 10.1093/pcp/pcj038 16556649 · DOI
  28. Signorelli S. Corpas F. J. Omar Borsani O. Barroso J. B. Monza J. (2013). Water stress induces a differential and spatially distributed nitro-oxidative stress response in roots and leaves of Lotus japonicus. Plant Sci. 201–202, 137– 146 10.1016/j.plantsci.2012.12.004 23352412 · DOI
  29. Sokolovsky M. Riordan J. F. Vallee B. L. (1967). Conversion of 3-nitrotyrosine to 3-aminotyrosine in peptides and proteins. Biochem. Biophys. Res. Commun. 27, 20– 25 10.1016/S0006-291X(67)80033-0 6048236 · DOI
  30. Souza J. M. Peluffo G. Radi R. (2008). Protein tyrosine nitration -functional alteration or just a biomarker? Free Radic. Biol. Med. 45, 357– 366 10.1016/j.freeradbiomed.2008.04.010 18460345 · DOI
  31. Tanou G. Filippou P. Belghazi M. Job D. Diamantidis G. Fotopoulos V. (2012). Oxidative and nitrosative-based signaling and associated post-translational modifications orchestrate the acclimation of citrus plants to salinity stress. Plant J. 72, 585– 599 10.1111/j.1365-313X.2012.05100.x 22780834 · DOI
  32. Valderrama R. Corpas F. J. Carreras A. Fernández-Ocaña A. Chaki M. Luque F. (2007). Nitrosative stress in plants. FEBS Lett. 581, 453– 461 10.1016/j.febslet.2007.01.006 17240373 · DOI
  33. van der Vliet A. Eiserich J. P. Shigenaga M. K. Cross C. E. (1999). Reactive nitrogen species and tyrosine nitration in the respiratory tract: epiphenomena or a pathobiologic mechanism of disease? Am. J. Respir. Crit. Care Med. 160, 1– 9 10390372
  34. Ytterberg A. J. Jensen O. N. (2010). Modification-specific proteomics in plant biology. J. Proteomics 73, 2249– 2266 10.1016/j.jprot.2010.06.002 20541636 · DOI

Cited by

Sorted by citations

Authors
Corpas, F. J., Palma, J. M., del Río, L. A., & Barroso, J. B.
Affiliations
  • Consejo Superior de Investigaciones Científicas (ES)
  • Universidad de Jaén (ES)
Corresponding author
Corpas, Francisco J.
ORCID
Venue
Frontiers in Plant Science
Publisher
Frontiers Media SA
Published
2013
Volume
4
Pages
29-29
ISSN
1664-462X (ISSN-L)
DOI
10.3389/fpls.2013.00029
PMC
PMC3580390
OpenAlex
W2007821357
Cited by
128
References
0
Citations by year
2026: 6 · 2025: 2 · 2024: 1 · 2023: 6 · 2022: 10 · 2021: 12 · 2020: 10 · 2019: 14 · 2018: 8 · 2017: 14 · 2016: 12 · 2015: 14 · 2014: 10 · 2013: 8
FWCI
17.71
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • Frontiers in Plant Science (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • Ministerio de Ciencia e Innovación (ACI2009-0860, BIO2009-12003-C02-01, BIO2009-12003-C02-02, AGL2011-26044, BIO192)
  • Junta de Andalucía (BIO 192, BIO-286)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Stress Responses and Tolerance
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
  • Health Sciences › Medicine › Physiology › Nitric Oxide and Endothelin Effects
Keywords
tyrosine nitration, higher plants, reactive nitrogen species, post-translational modification, abiotic stress, nitrated proteins, plant proteome

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