Developmental and reproductive toxic effects of exposure to microplastics: A review of associated signaling pathways

Plasticenta: First evidence of microplastics in human placenta

Ragusa, A., Svelato, A., Santacroce, C., Catalano, P., Notarstefano, V., Carnevali, O., Papa, F., Rongioletti, M. C. A., Baiocco, F., Draghi, S., et al. (2021) · Environment International · doi:10.1016/j.envint.2020.106274 · Cited by 3,474

Oyster reproduction is affected by exposure to polystyrene microplastics

Sussarellu, R., Suquet, M., Thomas, Y., Christophe Lambert, B., Fabioux, C., Arsenault-Pernet, E.-J., Goïc, N. L., Quillien, V., Mingant, C., Epelboin, Y., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1519019113 · Cited by 1,896

Detection of microplastics in human lung tissue using μFTIR spectroscopy

Jenner, L. C., Rotchell, J. M., Bennett, R. T., Cowen, M., Tentzeris, V., & Sadofsky, L. R. (2022) · Science of The Total Environment · doi:10.1016/j.scitotenv.2022.154907 · Cited by 1,536

Effect of Oxidative Stress on Male Reproduction

Agarwal, A. K., Virk, G., Ong, C. S. H., & du Plessis, S. S. (2014) · The World Journal of Men s Health · doi:10.5534/wjmh.2014.32.1.1 · Cited by 1,335

Presence of airborne microplastics in human lung tissue

Amato-Lourenço, L. F., Carvalho-Oliveira, R., Júnior, G. R., dos Santos Galvão, L., Ando, R. A., & Mauad, T. (2021) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2021.126124 · Cited by 1,329

The Impact of Polystyrene Microplastics on Feeding, Function and Fecundity in the Marine Copepod Calanus helgolandicus

Cole, M., Lindeque, P., Fileman, E., Halsband, C., & Galloway, T. S. (2015) · Environmental Science & Technology · doi:10.1021/es504525u · Cited by 1,308

Plastics and microplastics in the oceans: From emerging pollutants to emerged threat

Avio, C. G., Gorbi, S., & Regoli, F. (2017) · Marine Environmental Research · doi:10.1016/j.marenvres.2016.05.012 · Cited by 1,248

Characterisation, quantity and sorptive properties of microplastics extracted from cosmetics

Napper, I. E., Bakir, A., Rowland, S. J., & Thompson, R. C. (2015) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2015.07.029 · Cited by 1,026

Effect of microplastics in water and aquatic systems

Issac, M. N., & Kandasubramanian, B. (2021) · Environmental Science and Pollution Research · doi:10.1007/s11356-021-13184-2 · Cited by 919

Polyester textiles as a source of microplastics from households: A mechanistic study to understand microfiber release during washing

Hernandez, E., Nowack, B., & Mitrano, D. M. (2017) · Environmental Science & Technology · doi:10.1021/acs.est.7b01750 · Cited by 779

Polystyrene microplastics induced male reproductive toxicity in mice

Jin, H., Ma, T., Sha, X., Liu, Z., Zhou, Y., Meng, X., Chen, Y., Han, X., & Ding, J. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.123430 · Cited by 686

Fast identification of microplastics in complex environmental samples by a thermal degradation method

Dümichen, E., Eisentraut, P., Bannick, C. G., Barthel, A.-K., Senz, R., & Braun, U. (2017) · Chemosphere · doi:10.1016/j.chemosphere.2017.02.010 · Cited by 641

Exposure to polystyrene microplastics causes reproductive toxicity through oxidative stress and activation of the p38 MAPK signaling pathway

Xie, X., Deng, T., Duan, J., Xie, J., Yuan, J., & Chen, M. (2019) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2019.110133 · Cited by 635

Nrf2 regulates ROS production by mitochondria and NADPH oxidase

Kovac, S., Angelova, P. R., Holmström, K. M., Zhang, Y., Dinkova‐Kostova, A. T., & Abramov, A. Y. (2014) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2014.11.021 · Cited by 621

Accumulation of polystyrene microplastics in juvenile Eriocheir sinensis and oxidative stress effects in the liver

Yu, P., Liu, Z., Wu, D., Chen, M., Lv, W., & Zhao, Y. (2018) · Aquatic Toxicology · doi:10.1016/j.aquatox.2018.04.015 · Cited by 620

Polystyrene microplastics cause tissue damages, sex-specific reproductive disruption and transgenerational effects in marine medaka (Oryzias melastigma)

Wang, J., Li, Y., Lü, L., Zheng, M., Zhang, X., Tian, H., Wang, W., & Ru, S. (2019) · Environmental Pollution · doi:10.1016/j.envpol.2019.113024 · Cited by 573

Detection of Microplastic in Human Placenta and Meconium in a Clinical Setting

Braun, T., Ehrlich, L., Henrich, W., Koeppel, S., Lomako, I., Schwabl, P., & Liebmann, B. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13070921 · Cited by 546

Toxic effects on bioaccumulation, hematological parameters, oxidative stress, immune responses and neurotoxicity in fish exposed to microplastics: A review

Kim, J., Yu, Y.-B., & Choi, J.-H. (2021) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2021.125423 · Cited by 512

Reproductive toxicity of polystyrene microplastics: In vivo experimental study on testicular toxicity in mice

Hou, B., Wang, F., Liu, T., & Wang, Z. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.124028 · Cited by 497

First evidence of microplastics in Antarctic snow

Aves, A. R., Revell, L. E., Gaw, S., Ruffell, H., Schuddeboom, A. J., Wotherspoon, N. E., Larue, M. A., & McDonald, A. (2022) · The Cryosphere · doi:10.5194/tc-16-2127-2022 · Cited by 463

Polystyrene microplastics cause granulosa cells apoptosis and fibrosis in ovary through oxidative stress in rats

An, R., Wang, X., Yang, L., Zhang, J., Wang, N., Xu, F., Hou, Y., Zhang, H., & Zhang, L. (2020) · Toxicology · doi:10.1016/j.tox.2020.152665 · Cited by 462

A comparative review of microplastics and nanoplastics: Toxicity hazards on digestive, reproductive and nervous system

Yin, K., Wang, Y., Zhao, H., Wang, D., Guo, M., Mu, M., Liu, Y., Nie, X., Li, B., Li, J., et al. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.145758 · Cited by 447

Polystyrene microplastics induced female reproductive toxicity in mice

Liu, Z., Zhuan, Q., Zhang, L., Meng, L., Fu, X., & Hou, Y. (2022) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2021.127629 · Cited by 444

Occurrence and identification of microplastics in tap water from China

Tong, H., Jiang, Q., Hu, X., & Zhong, X. (2020) · Chemosphere · doi:10.1016/j.chemosphere.2020.126493 · Cited by 442

Endocrine control of spermatogenesis: Role of FSH and LH/ testosterone

Ramaswamy, S., & Weinbauer, G. F. (2014) · Spermatogenesis · doi:10.1080/21565562.2014.996025 · Cited by 411

Polystyrene microplastics lead to pyroptosis and apoptosis of ovarian granulosa cells via NLRP3/Caspase-1 signaling pathway in rats

Hou, J., Lei, Z., Cui, L., Hou, Y., Long, Y., An, R., Wang, Q., Li, S., Zhang, H., & Zhang, L. (2021) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2021.112012 · Cited by 398

Regulation of Autophagy by mTOR Signaling Pathway

Wang, Y., & Zhang, H. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-981-15-0602-4_3 · Cited by 363

Microplastics in house dust from 12 countries and associated human exposure

Zhang, J., Wang, L., & Kannan, K. (2019) · Environment International · doi:10.1016/j.envint.2019.105314 · Cited by 361

Microplastic digestion generates fragmented nanoplastics in soils and damages earthworm spermatogenesis and coelomocyte viability

Kwak, J. I., & An, Y. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.124034 · Cited by 360

Comparing the effects of polystyrene microplastics exposure on reproduction and fertility in male and female mice

Wei, Z., Wang, Y., Wang, S., Xie, J., Han, Q., & Chen, M. (2021) · Toxicology · doi:10.1016/j.tox.2021.153059 · Cited by 337

Individual and combined toxicogenetic effects of microplastics and heavy metals (Cd, Pb, and Zn) perturb gut microbiota homeostasis and gonadal development in marine medaka (Oryzias melastigma)

Wang, Y., Hamid, N., Deng, S., Jia, P., & Pei, D. (2020) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2020.122795 · Cited by 325

Maternal exposure to different sizes of polystyrene microplastics during gestation causes metabolic disorders in their offspring

Luo, T., Zhang, Y., Wang, C., Wang, X., Zhou, J., Shen, M., Zhao, Y., Fu, Z., & Jin, Y. (2019) · Environmental Pollution · doi:10.1016/j.envpol.2019.113122 · Cited by 321

Chronic exposure to polystyrene microplastics induced male reproductive toxicity and decreased testosterone levels via the LH-mediated LHR/cAMP/PKA/StAR pathway

Jin, H., Yan, M., Pan, C., Liu, Z., Sha, X., Jiang, C., Li, L., Pan, M., Li, D., Han, X., et al. (2022) · Particle and Fibre Toxicology · doi:10.1186/s12989-022-00453-2 · Cited by 314

Repeated-oral dose toxicity of polyethylene microplastics and the possible implications on reproduction and development of the next generation

Park, E., Han, J.-S., Park, E.-J., Seong, E., Lee, G., Kim, D., Son, H., Han, H., & Lee, B. (2020) · Toxicology Letters · doi:10.1016/j.toxlet.2020.01.008 · Cited by 305

Ovarian stiffness increases with age in the mammalian ovary and depends on collagen and hyaluronan matrices

Amargant, F., Manuel, S. L., Tu, Q., Parkes, W. S., Rivas, F., Zhou, L. T., Rowley, J. E., Villanueva, C. E., Hornick, J. E., Shekhawat, G. S., et al. (2020) · Aging Cell · doi:10.1111/acel.13259 · Cited by 280

Exposure to polystyrene microplastics impairs gonads of zebrafish (Danio rerio)

Qiang, L., & Cheng, J. (2020) · Chemosphere · doi:10.1016/j.chemosphere.2020.128161 · Cited by 265

Genotoxic and cytotoxic effects of polyethylene microplastics on human peripheral blood lymphocytes

Çobanoğlu, H., Belivermiş, M., Sıkdokur, E., Kılıç, Ö., & Çayır, A. (2021) · Chemosphere · doi:10.1016/j.chemosphere.2021.129805 · Cited by 244

Transgenerational effects and recovery of microplastics exposure in model populations of the freshwater cladoceran Daphnia magna Straus

Martins, A., & Guilhermino, L. M. (2018) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2018.03.054 · Cited by 243

Reproductive toxicity of primary and secondary microplastics to three cladocerans during chronic exposure

Jaikumar, G., Brun, N. R., Vijver, M. G., & Bosker, T. (2019) · Environmental Pollution · doi:10.1016/j.envpol.2019.03.085 · Cited by 238

Polystyrene microplastics disturb maternal-fetal immune balance and cause reproductive toxicity in pregnant mice

Hu, J., Qin, X., Zhang, J., Zhu, Y., Zeng, W., Lin, Y., & Liu, X. (2021) · Reproductive Toxicology · doi:10.1016/j.reprotox.2021.10.002 · Cited by 237

Microplastics enhance the developmental toxicity of synthetic phenolic antioxidants by disturbing the thyroid function and metabolism in developing zebrafish

Zhao, H., Xu, J., Yan, Z., Ren, H., & Zhang, Y. (2020) · Environment International · doi:10.1016/j.envint.2020.105750 · Cited by 221

Maternal exposure to polystyrene nanoplastics during gestation and lactation induces hepatic and testicular toxicity in male mouse offspring

Huang, T., Zhang, W., Lin, T., Liu, S., Sun, Z., Liu, F., Yuan, Y., Xiang, X., Kuang, H., Yang, B., et al. (2022) · Food and Chemical Toxicology · doi:10.1016/j.fct.2021.112803 · Cited by 220

The effects of microplastic on freshwater Hydra attenuata feeding, morphology & reproduction

Murphy, F., & Quinn, B. (2017) · Environmental Pollution · doi:10.1016/j.envpol.2017.11.029 · Cited by 217

Polystyrene microplastics induce blood–testis barrier disruption regulated by the MAPK-Nrf2 signaling pathway in rats

Li, S., Wang, Q., Yu, H., Long, Y., Sun, Y., Xu, N., Wang, N., Lei, Z., Hou, J., Jin, Y., et al. (2021) · Environmental Science and Pollution Research · doi:10.1007/s11356-021-13911-9 · Cited by 205

Polystyrene microplastics disrupt the blood-testis barrier integrity through ROS-Mediated imbalance of mTORC1 and mTORC2

Wei, Y., Zhou, Y., Long, C., Wu, H., Hong, Y., Fu, Y., Wang, J., Wu, Y., Shen, L., & Wei, G. (2021) · Environmental Pollution · doi:10.1016/j.envpol.2021.117904 · Cited by 203

Molecular regulation of steroidogenesis in endocrine Leydig cells

Tremblay, J. (2015) · Steroids · doi:10.1016/j.steroids.2015.08.001 · Cited by 198

Microplastics: A Threat for Male Fertility

D’Angelo, S., & Meccariello, R. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18052392 · Cited by 193

Microplastics in wastewater: microfiber emissions from common household laundry

Galvão, A. F., Aleixo, M., de Pablo, H., Lopes, C., & Raimundo, J. (2020) · Environmental Science and Pollution Research · doi:10.1007/s11356-020-08765-6 · Cited by 187

Oxidative stress mediated by the TLR4/NOX2 signalling axis is involved in polystyrene microplastic-induced uterine fibrosis in mice

Wu, H., Xu, T., Chen, T., Liu, J., & Xu, S. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.155825 · Cited by 181

Low level of polystyrene microplastics decreases early developmental toxicity of phenanthrene on marine medaka (Oryzias melastigma)

Li, Y., Wang, J., Yang, G., Lü, L., Zheng, Y., Zhang, Q., Zhang, X., Tian, H., Wang, W., & Ru, S. (2019) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2019.121586 · Cited by 151

Embryotoxicity of polystyrene microplastics in zebrafish Danio rerio

Marco, G. D., Conti, G. O., Giannetto, A., Cappello, T., Galati, M., Iaria, C., Pulvirenti, E., Capparucci, F., Mauceri, A., Ferrante, M., et al. (2021) · Environmental Research · doi:10.1016/j.envres.2021.112552 · Cited by 148

Photo-Oxidative Degradation Mitigated the Developmental Toxicity of Polyamide Microplastics to Zebrafish Larvae by Modulating Macrophage-Triggered Proinflammatory Responses and Apoptosis

Zou, W., Xia, M., Jiang, K., Cao, Z., Zhang, X., & Hu, X. (2020) · Environmental Science & Technology · doi:10.1021/acs.est.0c05399 · Cited by 129

Exposure to microplastics leads to a defective ovarian function and change in cytoskeleton protein expression in rat

Haddadi, A., Kessabi, K., Boughammoura, S., Rhouma, M. B., Mlouka, R., Bannı, M., & Messaoudi, I. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-021-18218-3 · Cited by 126

Tight junctions in the testis: new perspectives

Mruk, D. D., & Cheng, C. Y. (2010) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2010.0010 · Cited by 117

Dose-Dependent Effect of Polystyrene Microplastics on the Testicular Tissues of the Male Sprague Dawley Rats

Ijaz, M. U., Shahzadi, S., Samad, A. R., Ehsan, N., Ahmed, H., Tahir, A., Rehman, H., & Anwar, H. (2021) · Dose-Response · doi:10.1177/15593258211019882 · Cited by 108

How microplastic components influence the immune system and impact on children health: Focus on cancer

Mendoza, M. S., Castro, K. E. N., Arreola, M. I. P., Garay-Canales, C. A., & Morales‐Montor, J. (2020) · Birth Defects Research · doi:10.1002/bdr2.1779 · Cited by 105

Insights of Crosstalk between p53 Protein and the MKK3/MKK6/p38 MAPK Signaling Pathway in Cancer

Stramucci, L., Pranteda, A., & Bossi, G. (2018) · Cancers · doi:10.3390/cancers10050131 · Cited by 104

Investigation on sodium valproate induced germ cell damage, oxidative stress and genotoxicity in male Swiss mice

Khan, S., Ahmad, T., Parekh, C. V., Trivedi, P. P., Kushwaha, S., & Jena, G. (2011) · Reproductive Toxicology · doi:10.1016/j.reprotox.2011.09.007 · Cited by 97

Polystyrene microplastics induced male reproductive toxicity and transgenerational effects in freshwater prawn

Sun, S., Jin, Y., Luo, P., & Shi, X. (2022) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2022.156820 · Cited by 94

Microplastics increase the accumulation of phenanthrene in the ovaries of marine medaka (Oryzias melastigma) and its transgenerational toxicity

Li, Y., Yang, G., Wang, J., Lü, L., Li, X., Zheng, Y., Zhang, Z., & Ru, S. (2021) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2021.127754 · Cited by 93

Environmental microplastics disrupt swimming activity in acute exposure in Danio rerio larvae and reduce growth and reproduction success in chronic exposure in D. rerio and Oryzias melastigma

Cormier, B., Cachot, J., Blanc, M., Cabar, M., Clérandeau, C., Dubocq, F., Bihanic, F. L., Morin, B., Zapata, S., Bégout, M., et al. (2022) · Environmental Pollution · doi:10.1016/j.envpol.2022.119721 · Cited by 92

Rictor/mTORC2 regulates blood‐testis barrier dynamics via its effects on gap junction communications and actin filament network

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Effects of polyvinyl chloride microplastics on reproduction, oxidative stress and reproduction and detoxification-related genes in Daphnia magna

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Signalling pathways regulating the blood–testis barrier

Lie, P. P. Y., Cheng, C. Y., & Mruk, D. D. (2012) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2012.12.009 · Cited by 85

Reproductive toxicity of UV-photodegraded polystyrene microplastics induced by DNA damage-dependent cell apoptosis in Caenorhabditis elegans

Chen, H., Yang, Y., Wang, C., Hua, X., Li, H., Xie, D., Xiang, M., & Yu, Y. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.152350 · Cited by 85

Improved Raman spectroscopy-based approach to assess microplastics in seafood

Leung, M. M.-L., Ho, Y., Lee, C. H., Wang, Y., Hu, M., Kwok, K. W. H., Chua, S. L., & Fang, J. K. (2021) · Environmental Pollution · doi:10.1016/j.envpol.2021.117648 · Cited by 80

Effects of pristine or contaminated polyethylene microplastics on zebrafish development

Tarasco, M., Gavaia, P. J., Bensimon‐Brito, A., Cordelières, F. P., Santos, T., Martins, G., de Castro, D. T., Silva, N., Cabrita, E., Bebianno, M. J., et al. (2022) · Chemosphere · doi:10.1016/j.chemosphere.2022.135198 · Cited by 78

rpS6 Regulates Blood-Testis Barrier Dynamics Through Arp3-Mediated Actin Microfilament Organization in Rat Sertoli Cells. An In Vitro Study

Mok, K., Chen, H., Lee, W. M., & Cheng, C. Y. (2015) · Endocrinology · doi:10.1210/en.2014-1791 · Cited by 75

rpS6 regulates blood-testis barrier dynamics via its effects on MMP-9 mediated by Akt signaling

Mok, K., Mruk, D. D., & Cheng, C. Y. (2014) · Journal of Cell Science · doi:10.1242/jcs.152231 · Cited by 75

Chronic toxic effects of polystyrene microplastics on reproductive parameters of male rats

Ilechukwu, I., Ehigiator, B. E., Ben, I. O., Okonkwo, C. J., Olorunfemi, O. S., Modo, E. U., Ilechukwu, C. E., & Ohagwa, N. J. (2022) · Environmental Analysis Health and Toxicology · doi:10.5620/eaht.2022015 · Cited by 69

Semen quality in workers producing reinforced plastic

Jelnes, J. E. (1988) · Reproductive Toxicology · doi:10.1016/0890-6238(88)90024-x · Cited by 60

Icariin protects mouse Leydig cell testosterone synthesis from the adverse effects of di(2-ethylhexyl) phthalate

Sun, J., Wang, D., Lin, J., Liu, Y., Xu, L., Lv, R., Mo, K., Lian, X., Xie, M., Xu, S., et al. (2019) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2019.114612 · Cited by 58

Mechanisms of NLRP3 inflammasome-mediated hepatic stellate cell activation: Therapeutic potential for liver fibrosis

Charan, H. V., Dwivedi, D. K., Khan, S., & Jena, G. (2022) · Genes & Diseases · doi:10.1016/j.gendis.2021.12.006 · Cited by 58

Mammalian target of rapamycin (mTOR): a central regulator of male fertility?

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The Inflammasome in Reproductive Biology: A Promising Target for Novel Therapies

Vaccari, J. P. D. R. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00008 · Cited by 35

NLRP3 inflammasome is involved in testicular inflammation induced by lipopolysaccharide in mice

Sano, M., Komiyama, H., Shinoda, R., Ozawa, R., Watanabe, H., Karasawa, T., Takahashi, M., Torii, Y., Iwata, H., Kuwayama, T., et al. (2022) · American Journal of Reproductive Immunology · doi:10.1111/aji.13527 · Cited by 34

Overview and Sources of Reactive Oxygen Species (ROS) in the Reproductive System

Ahmad, G., Almasry, M., Dhillon, A. S., Abuayyash, M. M., Kothandaraman, N., & Cakar, Z. (2017) · Springer eBooks · doi:10.1007/978-3-319-48427-3_1 · Cited by 33

Next Generation Reproductive and Developmental Toxicology: Crosstalk Into the Future

­Hougaard, K. S. (2021) · Frontiers in Toxicology · doi:10.3389/ftox.2021.652571 · Cited by 27

Increased incidence of infertility treatment among women working in the plastics industry

­Hougaard, K. S., Hannerz, H., Feveile, H., & Bonde, J. P. (2009) · Reproductive Toxicology · doi:10.1016/j.reprotox.2009.01.003 · Cited by 26

Microplastics as an Emerging Threat to the Global Environment and Human Health

Ghosh, S., Sinha, J. K., Ghosh, S. K., Vashisth, K., Han, S. S., & Bhaskar, R. (2023) · Sustainability · doi:10.3390/su151410821 · Cited by 493

The emerging role of microplastics in systemic toxicity: Involvement of reactive oxygen species (ROS)

Das, A. K. (2023) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2023.165076 · Cited by 404

Tissue accumulation of microplastics and potential health risks in human

Zhu, L., Kang, Y., Ma, M., Wu, Z., Zhang, L., Hu, R., Xu, Q., Zhu, J., Gu, X., & An, L. (2024) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2024.170004 · Cited by 317

Raman Microspectroscopy evidence of microplastics in human semen

Montano, L., Giorgini, E., Notarstefano, V., Notari, T., Ricciardi, M., Piscopo, M., & Motta, O. (2023) · Science of The Total Environment · doi:10.1016/j.scitotenv.2023.165922 · Cited by 243

The invisible Threat: Assessing the reproductive and transgenerational impacts of micro- and nanoplastics on fish

Yi, J., Ma, Y., Ruan, J., You, S., Ma, J., Yu, H., Zhao, J., Zhang, K., Yang, Q., Jin, L., et al. (2024) · Environment International · doi:10.1016/j.envint.2024.108432 · Cited by 80

A critical review on male-female reproductive and developmental toxicity induced by micro-plastics and nano-plastics through different signaling pathways

Ali, W., Buriro, R. S., Gandahi, J. A., Chen, Y., Aabdin, Z. U., Bhutto, S., Sun, J. G., Zhu, J., Liu, Z., & Zou, H. (2024) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2024.110976 · Cited by 47

The Reproductive Toxicity of Microplastics: From Environmental Contamination to Organ Distribution and Reproductive Hazards

Chakraborty, S., Ganguly, A., Adhikary, S., Bhattacharya, S., & Rajak, P. (2026) · Environmental Toxicology · doi:10.1002/tox.70171

Microplastics and reproductive health: implications for human health and areas for future research

Hyman, S., Kahn, L. G., & Cowell, W. (2026) · Human Reproduction · doi:10.1093/humrep/deag069 · Cited by 5

Microplastics: unraveling the signaling pathways involved in reproductive health

Tanveer, M., Mansha, N., Afzal, N., Khawar, M. B., Afzal, A., Afzal, H., Farooq, M., Ehsan, S., Rana, R., & Shahzaman, S. (2023) · Environmental Science and Pollution Research · doi:10.1007/s11356-023-29273-3 · Cited by 16

Mechanistic insights into microplastic-induced reproductive toxicity in aquatic organisms: A comprehensive review

Hasan, A., Hossain, M. F., Uddin, M., Khan, M. T., Saif, U. M., Hamed, M., Martyniuk, C. J., & Chivers, D. P. (2025) · Aquatic Toxicology · doi:10.1016/j.aquatox.2025.107478 · Cited by 22