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Cognitive functioning in major depression – a summary
Open accessAbstract
The aim of the present paper is to summarize the research during the past decade regarding cognitive functioning in Major Depressive Disorder (MDD). Cognitive impairment in the acute phase of illness has been frequently reported. The findings are shown in different cognitive domains, such as executive functions, attention, memory and psychomotor speed. Fewer reports have investigated cognitive functioning in MDD in longitudinal studies. Some longitudinal reports show that the impairment observed in the acute phase of illness may be long lasting despite symptom reduction and recovery. However, findings regarding cognitive functioning in depression are divergent. Factors that might contribute to the divergent findings, such as depression subtype, severity and comorbidity are discussed. Clinical implications and focus of future research directions is highlighted.In conclusion, depression is associated with cognitive impairment in the acute phase of illness, and some reports indicate that this impairment might be long lasting despite symptom reduction and recovery.
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“Cognitive symptoms of MDD include deficits in several domains, including processing speed, attention, executive function, learning, and memory [5-7].”
From Wearable technology for high-frequency cognitive and mood assessment in major depressive disorder: longitudinal observational study (2019) · cites this paper as [5]
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Metadata
- Authors
- Hammar, Å.
- Affiliations
- Haukeland University Hospital (NO)
- Corresponding author
- Hammar, Åsa
- ORCID
- Hammar, Åsa
- Venue
- Frontiers in Human Neuroscience
- Publisher
- Frontiers Media SA
- Published
- 2009
- Volume
- 3
- Pages
- 26-26
- ISSN
- 1662-5161 (ISSN-L)
- PMC
- PMC2759342
- OpenAlex
- W2091523152
- Cited by
- 491
- References
- 81
- Citations by year
- 2026: 16 · 2025: 19 · 2024: 25 · 2023: 31 · 2022: 40 · 2021: 35 · 2020: 31 · 2019: 53 · 2018: 43 · 2017: 46 · 2016: 36 · 2015: 26 · 2014: 23 · 2013: 19 · 2012: 17
- FWCI
- 11.26
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Frontiers in Human Neuroscience (publishedVersion, cc-by)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- major depressive disorder, cognitive impairment, executive function, attention, memory, psychomotor speed, depression subtypes, depression severity, comorbidities, recovery from depression
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