Cited by 491Treatment of Major DepressionNeural and Behavioral Psychology StudiesAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

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Cognitive functioning in major depression – a summary

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Hammar, Åsa·2009·Frontiers in Human Neuroscience

DOI 10.3389/neuro.09.026.2009PMC PMC2759342

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Abstract

The aim of the present paper is to summarize the research during the past decade regarding cognitive functioning in Major Depressive Disorder (MDD). Cognitive impairment in the acute phase of illness has been frequently reported. The findings are shown in different cognitive domains, such as executive functions, attention, memory and psychomotor speed. Fewer reports have investigated cognitive functioning in MDD in longitudinal studies. Some longitudinal reports show that the impairment observed in the acute phase of illness may be long lasting despite symptom reduction and recovery. However, findings regarding cognitive functioning in depression are divergent. Factors that might contribute to the divergent findings, such as depression subtype, severity and comorbidity are discussed. Clinical implications and focus of future research directions is highlighted.In conclusion, depression is associated with cognitive impairment in the acute phase of illness, and some reports indicate that this impairment might be long lasting despite symptom reduction and recovery.

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Authors: Hammar, Å.
Affiliations: Haukeland University Hospital (NO)
Corresponding author: Hammar, Åsa
ORCID: Hammar, Åsa
Venue: Frontiers in Human Neuroscience
Publisher: Frontiers Media SA
Published: 2009
Volume: 3
Pages: 26-26
ISSN: 1662-5161 (ISSN-L)
DOI: 10.3389/neuro.09.026.2009
PMC: PMC2759342
OpenAlex: W2091523152
Cited by: 491
References: 81
Citations by year: 2026: 16 · 2025: 19 · 2024: 25 · 2023: 31 · 2022: 40 · 2021: 35 · 2020: 31 · 2019: 53 · 2018: 43 · 2017: 46 · 2016: 36 · 2015: 26 · 2014: 23 · 2013: 19 · 2012: 17
FWCI: 11.26
Type: journal article
Language: en
Open access: gold
doi.org
Licence: cc-by
Locations: Frontiers in Human Neuroscience (publishedVersion, cc-by)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Topics: Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords: major depressive disorder, cognitive impairment, executive function, attention, memory, psychomotor speed, depression subtypes, depression severity, comorbidities, recovery from depression

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