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Cited by 44Antibiotic Use and ResistancePharmacy and Medical PracticesPharmaceutical Practices and Patient Outcomes

Mapping the implementation of a clinical pharmacist-driven antimicrobial stewardship programme at a tertiary care centre in South India

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Nampoothiri, Vrinda, Sudhir, Akkulath Sangita, Joseph, Mariam Varsha, Mohamed, Zubair, Menon, Vidya, Charani, Esmita, Singh, Sanjeev·2021·Antibiotics
DOI 10.3390/antibiotics10020220PMC PMC7926893
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Abstract

In many parts of the world, including in India, pharmacist roles in antimicrobial stewardship (AMS) programmes remain unexplored. We describe the evolution and effect of the role of adding clinical pharmacists to a multidisciplinary AMS at a tertiary care teaching hospital in Kerala, India. Through effective leadership, multidisciplinary AMS (February 2016) and antitubercular therapy (ATT) stewardship programmes (June 2017) were established. Clinical pharmacists were introduced as core members of the programmes, responsible for the operational delivery of key stewardship interventions. Pharmacy-led audit and feedback monitored the appropriateness of antimicrobial prescriptions and compliance to AMS/ATT recommendations. Between February 2016 and January 2017, 56% (742/1326) of antimicrobial prescriptions were appropriate, and 54% (318/584) of recommendations showed compliance. By the third year of the AMS, appropriateness increased to 80% (1752/2190), and compliance to the AMS recommendations to 70% (227/325). The appropriateness of ATT prescriptions increased from a baseline of 61% (95/157) in the first year, to 72% (62/86, June 2018-February 2019). The compliance to ATT recommendations increased from 42% (25/60) to 58% (14/24). Such a model can be effective in implementing sustainable change in low- and middle-income countries (LMICs) such as India, where the shortage of infectious disease physicians is a major impediment to the implementation and sustainability of AMS programmes.

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  • The paediatric surgical departments functioned in a hospital with established IPC and AMS programmes.

    “The paediatric surgical departments functioned in a hospital with established IPC and AMS programmes.22,25”

    From Rationalizing irrational prescribing—infection-related attitudes and practices across paediatric surgery specialties in a hospital in South India (2024) · cites this paper as [22]

    Section 2.3 (page not provided) states that the hospital initiated an AMS programme in February 2016 and describes its established activities. The passages do not establish that the hospital had an IPC programme or identify paediatric surgical departments, so those parts of the claim are unsupported by this source. (LLM, conf=0.86)

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Authors
Nampoothiri, V., Sudhir, A. S., Joseph, M. V., Mohamed, Z., Menon, V., Charani, E., & Singh, S.
Affiliations
  • Amrita Vishwa Vidyapeetham (IN)
  • Imperial College London (GB)
Corresponding author
Singh, Sanjeev
ORCID
Venue
Antibiotics
Publisher
MDPI AG
Published
2021-02-23
Volume
10
Issue
2
Pages
220
ISSN
2079-6382 (ISSN-L)
DOI
10.3390/antibiotics10020220
PMC
PMC7926893
OpenAlex
W3132537326
Cited by
44
References
28
Citations by year
2026: 3 · 2025: 6 · 2024: 13 · 2023: 10 · 2022: 8 · 2021: 4
FWCI
5.07
Type
journal article
Language
en
Open access
Licence
Locations
  • Antibiotics (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • Global Challenges Research Fund
  • Economic and Social Research Council (ES/P008313/1)
Topics
  • Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Antibiotic Use and Resistance
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacy and Medical Practices
  • Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
Keywords
antimicrobial stewardship, clinical pharmacists, tertiary care hospital, low- and middle-income countries, pharmacist role

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