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Cited by 403

The DOI matches its Crossref record; 214 of the 214 references it cites were found in a registry or an index.

Role of the Encapsulation in Bioavailability of Phenolic Compounds

Open access
Grgić, Josipa, Šelo, Gordana, Planinić, Mirela, Tišma, Marina, Bucić-Kojić, Ana·2020·Antioxidants

Abstract

Plant-derived phenolic compounds have multiple positive health effects for humans attributed to their antioxidative, anti-inflammatory, and antitumor properties, etc. These effects strongly depend on their bioavailability in the organism. Bioaccessibility, and consequently bioavailability of phenolic compounds significantly depend on the structure and form in which they are introduced into the organism, e.g., through a complex food matrix or as purified isolates. Furthermore, phenolic compounds interact with other macromolecules (proteins, lipids, dietary fibers, polysaccharides) in food or during digestion, which significantly influences their bioaccessibility in the organism, but due to the complexity of the mechanisms through which phenolic compounds act in the organism this area has still not been examined sufficiently. Simulated gastrointestinal digestion is one of the commonly used in vitro test for the assessment of phenolic compounds bioaccessibility. Encapsulation is a method that can positively affect bioaccessibility and bioavailability as it ensures the coating of the active component and its targeted delivery to a specific part of the digestive tract and controlled release. This comprehensive review aims to present the role of encapsulation in bioavailability of phenolic compounds as well as recent advances in coating materials used in encapsulation processes. The review is based on 258 recent literature references.

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Crossref · 10.3390/antiox9100923

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Metadata

Authors
Grgić, J., Šelo, G., Planinić, M., Tišma, M., & Bucić-Kojić, A.
Venue
Antioxidants
Publisher
MDPI AG
Published
2020-09-26
Volume
9
Issue
10
Pages
923
ISSN
2076-3921 (ISSN-L)
OpenAlex
W3088637818
Cited by
403
References
214
FWCI
22.47
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Role of the Encapsulation in Bioavailability of Phenolic Compounds. https://app.cochat.ai/papers/10.3390/antiox9100923
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Grgić, J., Šelo, G., Planinić, M., Tišma, M., & Bucić-Kojić, A. (2020). Role of the Encapsulation in Bioavailability of Phenolic Compounds. Antioxidants. https://doi.org/10.3390/antiox9100923

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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