Cited by 41Garlic and Onion StudiesHormonal and reproductive studiesSperm and Testicular Function

Testosterone in Males as Enhanced by Onion (Allium Cepa L.)

Open access
Banihani, Saleem Ali·2019·Biomolecules

Abstract

Testosterone (17β-Hydroxyandrost-4-en-3-one) is the main sex hormone in males. Maintaining and enhancing testosterone level in men is an incessant target for many researchers. Examples of such research approaches is to utilize specific types of food or dietary supplements as a safe and easily reached means. Here, specifically, since 1967 until now, many research studies have revealed the effect of onion on testosterone; however, this link has yet to be collectively reviewed or summarized. To accomplish this contribution, we searched the Scopus, Web of Science, and PubMed databases for full articles or abstracts (published in English language) from April 1967 through December 2018 using the keywords “onion” versus “testosterone”. In addition, a number of related published articles from the same databases were included to improve the integrity of the discussion, and hence the edge of the future directions. In summary, there is an evidence that onions enhance testosterone level in males. The mechanisms by which this occurs is mainly by increasing the production of luteinizing hormone, enhancing the antioxidant defense mechanism in the tests, neutralizing the damaging effects of the generated free radicals, ameliorating insulin resistance, promoting nitric oxide production, and altering the activity of adenosine 5′-monophosphate -activated protein kinase. However, this effect requires further approval in humans, mainly by conducting clinical trials.

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Crossref · 10.3390/biom9020075

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Authors
Banihani, S. A.
Affiliations
Jordan University of Science and Technology (JO)
Corresponding author
Banihani, Saleem Ali
Venue
Biomolecules
Publisher
MDPI AG
Published
2019-02-21
Volume
9
Issue
2
Pages
75
ISSN
2218-273X (ISSN-L)
OpenAlex
W2915786647
Cited by
41
References
68
Citations by year
2026: 2 · 2025: 4 · 2024: 6 · 2023: 9 · 2022: 6 · 2021: 6 · 2020: 6 · 2019: 1 · 2018: 1
FWCI
0.43
Type
journal article
Language
en
Open access
Locations
  • Biomolecules (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Funders
Jordan University of Science and Technology
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Garlic and Onion Studies
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Hormonal and reproductive studies
  • Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
Keywords
testosterone, onion, dietary supplements, androgens, luteinizing hormone, antioxidant defense, free radicals, insulin resistance, nitric oxide, AMPK, testis
MeSH terms
Antioxidants, Humans, Male, Plant Extracts, Testosterone, Onions

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