The DOI matches its Crossref record; 349 of the 349 references it cites were found in a registry or an index.
Various AAV Serotypes and Their Applications in Gene Therapy: An Overview
Open accessAbstract
Despite scientific discoveries in the field of gene and cell therapy, some diseases still have no effective treatment. Advances in genetic engineering methods have enabled the development of effective gene therapy methods for various diseases based on adeno-associated viruses (AAVs). Today, many AAV-based gene therapy medications are being investigated in preclinical and clinical trials, and new ones are appearing on the market. In this article, we present a review of AAV discovery, properties, different serotypes, and tropism, and a following detailed explanation of their uses in gene therapy for disease of different organs and systems.
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Citations
Cites
Adeno-associated virus vector as a platform for gene therapy delivery
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Clades of Adeno-Associated Viruses Are Widely Disseminated in Human Tissues
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Cited by
Adeno-associated virus as a delivery vector for gene therapy of human diseases
Wang, J.-H., Gessler, D. J., Zhan, W., Gallagher, T. L., & Gao, G. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01780-w · Cited by 904
Innate immune sensing of adeno-associated virus vectors
Cao, D., Byrne, B. J., de Jong, Y. P., Terhorst, C., Duan, D., Herzog, R. W., & Kumar, S. R. P. (2024) · Human Gene Therapy · doi:10.1089/hum.2024.040 · Cited by 50
Kitaeva, K. V., Solovyeva, V. V., Blatt, N. L., & Rizvanov, A. A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25010643 · Cited by 7
Self-citation
Metadata
- Authors
- Issa, S. S., Shaimardanova, A. A., Solovyeva, V. V., & Rizvanov, A. A.
- Venue
- Cells
- Publisher
- MDPI AG
- Published
- 2023-03-01
- Volume
- 12
- Issue
- 5
- Pages
- 785
- ISSN
- 2073-4409 (ISSN-L)
- OpenAlex
- W4322770338
- Cited by
- 313
- References
- 349
- FWCI
- 45.85
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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