Cited by 1,452

The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.

Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model

Kota, Janaiah, Chivukula, Raghu R., O'Donnell, Kathryn A., Wentzel, Erik A., Montgomery, Chrystal L., Hwang, Hun-Way, Chang, Tsung-Cheng, Vivekanandan, Perumal, Torbenson, Michael, Clark, K. Reed, Mendell, Jerry R., Mendell, Joshua T.·2009·Cell

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.cell.2009.04.021

Cites

13 of 13 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Show all 13 references

Research works printed but not linked: 52

  1. Alexander, 2008, Potential of AAV vectors in the treatment of metabolic disease, Gene Ther., 15, 831, 10.1038/gt.2008.64 · DOI
  2. Beer, 2004, Developmental context determines latency of MYC-induced tumorigenesis, PLoS Biol., 2, e332, 10.1371/journal.pbio.0020332 · DOI
  3. Betel, 2008, The microRNA.org resource: targets and expression, Nucleic Acids Res., 36, D149, 10.1093/nar/gkm995 · DOI
  4. Bommer, 2007, p53-Mediated activation of miRNA34 candidate tumor-suppressor genes, Curr. Biol., 17, 1298, 10.1016/j.cub.2007.06.068 · DOI
  5. Calin, 2006, MicroRNA signatures in human cancers, Nat. Rev. Cancer, 6, 857, 10.1038/nrc1997 · DOI
  6. Calin, 2004, Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers, Proc. Natl. Acad. Sci. USA, 101, 2999, 10.1073/pnas.0307323101 · DOI
  7. Carter, 2005, Adeno-associated virus vectors in clinical trials, Hum. Gene Ther., 16, 541, 10.1089/hum.2005.16.541 · DOI
  8. Chang, 2008, Widespread microRNA repression by Myc contributes to tumorigenesis, Nat. Genet., 40, 43, 10.1038/ng.2007.30 · DOI
  9. de Fougerolles, 2007, Interfering with disease: a progress report on siRNA-based therapeutics, Nat. Rev. Drug Discov., 6, 443, 10.1038/nrd2310 · DOI
  10. Elmen, 2008, LNA-mediated microRNA silencing in non-human primates, Nature, 452, 896, 10.1038/nature06783 · DOI · Paper page
  11. Esau, 2006, miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting, Cell Metab., 3, 87, 10.1016/j.cmet.2006.01.005 · DOI · Paper page
  12. Esquela-Kerscher, 2008, The let-7 microRNA reduces tumor growth in mouse models of lung cancer, Cell Cycle, 7, 759, 10.4161/cc.7.6.5834 · DOI
  13. Felsher, 1999, Reversible tumorigenesis by MYC in hematopoietic lineages, Mol. Cell, 4, 199, 10.1016/S1097-2765(00)80367-6 · DOI
  14. Gao, 2002, Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy, Proc. Natl. Acad. Sci. USA, 99, 11854, 10.1073/pnas.182412299 · DOI · Paper page
  15. Gaur, 2007, Characterization of microRNA expression levels and their biological correlates in human cancer cell lines, Cancer Res., 67, 2456, 10.1158/0008-5472.CAN-06-2698 · DOI · Paper page
  16. Giering, 2008, Expression of shRNA from a tissue-specific pol II promoter is an effective and safe RNAi therapeutic, Mol. Ther., 16, 1630, 10.1038/mt.2008.144 · DOI
  17. Grimm, 2007, RNAi and Gene Therapy: a mutual attraction, Hematology (Am Soc Hematol Educ Program), 2007, 473, 10.1182/asheducation-2007.1.473 · DOI
  18. Grimson, 2007, MicroRNA targeting specificity in mammals: determinants beyond seed pairing, Mol. Cell, 27, 91, 10.1016/j.molcel.2007.06.017 · DOI · Paper page
  19. He, 2007, microRNAs join the p53 network–another piece in the tumour-suppression puzzle, Nat. Rev. Cancer, 7, 819, 10.1038/nrc2232 · DOI
  20. Hwang, 2007, A hexanucleotide element directs microRNA nuclear import, Science, 315, 97, 10.1126/science.1136235 · DOI
  21. Johnson, 2005, RAS is regulated by the let-7 microRNA family, Cell, 120, 635, 10.1016/j.cell.2005.01.014 · DOI
  22. Kashuba, 2004, RBSP3 (HYA22) is a tumor suppressor gene implicated in major epithelial malignancies, Proc. Natl. Acad. Sci. USA, 101, 4906, 10.1073/pnas.0401238101 · DOI
  23. Kato, 2008, microRNAs: small molecules with big roles—C. elegans to human cancer, Biol. Cell, 100, 71, 10.1042/BC20070078 · DOI
  24. Kim, 2005, MicroRNA biogenesis: coordinated cropping and dicing, Nat. Rev. Mol. Cell Biol., 6, 376, 10.1038/nrm1644 · DOI · Paper page
  25. Kloosterman, 2006, The diverse functions of microRNAs in animal development and disease, Dev. Cell, 11, 441, 10.1016/j.devcel.2006.09.009 · DOI · Paper page
  26. Kumar, 2008, Suppression of non-small cell lung tumor development by the let-7 microRNA family, Proc. Natl. Acad. Sci. USA, 105, 3903, 10.1073/pnas.0712321105 · DOI
  27. Kumar, 2007, Impaired microRNA processing enhances cellular transformation and tumorigenesis, Nat. Genet., 39, 673, 10.1038/ng2003 · DOI
  28. Love, 2008, Not miR-ly small RNAs: big potential for microRNAs in therapy, J. Allergy Clin. Immunol., 121, 309, 10.1016/j.jaci.2007.12.1167 · DOI
  29. Lu, 2005, MicroRNA expression profiles classify human cancers, Nature, 435, 834, 10.1038/nature03702 · DOI
  30. Lujambio, 2007, CpG island hypermethylation of tumor suppressor microRNAs in human cancer, Cell Cycle, 6, 1455, 10.4161/cc.6.12.4408 · DOI
  31. McBride, 2008, Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: implications for the therapeutic development of RNAi, Proc. Natl. Acad. Sci. USA, 105, 5868, 10.1073/pnas.0801775105 · DOI
  32. McCarty, 2008, Self-complementary AAV vectors; advances and applications, Mol. Ther., 16, 1648, 10.1038/mt.2008.171 · DOI · Paper page
  33. Nakai, 2005, Unrestricted hepatocyte transduction with adeno-associated virus serotype 8 vectors in mice, J. Virol., 79, 214, 10.1128/JVI.79.1.214-224.2005 · DOI
  34. O'Donnell, 2005, c-Myc-regulated microRNAs modulate E2F1 expression, Nature, 435, 839, 10.1038/nature03677 · DOI · Paper page
  35. Park, 2008, Cancer gene therapy using adeno-associated virus vectors, Front. Biosci., 13, 2653, 10.2741/2872 · DOI
  36. Pathak, 2008, Nano-vectors for efficient liver specific gene transfer, Int. J. Nanomedicine, 3, 31
  37. Peng, 2000, Transduction of hepatocellular carcinoma (HCC) using recombinant adeno-associated virus (rAAV): in vitro and in vivo effects of genotoxic agents, J. Hepatol., 32, 975, 10.1016/S0168-8278(00)80102-6 · DOI
  38. Raver-Shapira, 2007, Transcriptional activation of miR-34a contributes to p53-mediated apoptosis, Mol. Cell, 26, 731, 10.1016/j.molcel.2007.05.017 · DOI
  39. Roberts, 2008, Sorafenib in liver cancer–just the beginning, N. Engl. J. Med., 359, 420, 10.1056/NEJMe0802241 · DOI
  40. Rodino-Klapac, 2007, A translational approach for limb vascular delivery of the micro-dystrophin gene without high volume or high pressure for treatment of Duchenne muscular dystrophy, J. Transl. Med., 5, 45, 10.1186/1479-5876-5-45 · DOI
  41. Shen, 2008, A novel and effective hepatocyte growth factor kringle 1 domain and p53 cocktail viral gene therapy for the treatment of hepatocellular carcinoma, Cancer Lett., 272, 268, 10.1016/j.canlet.2008.03.064 · DOI
  42. Stenvang, 2008, The utility of LNA in microRNA-based cancer diagnostics and therapeutics, Semin. Cancer Biol., 18, 89, 10.1016/j.semcancer.2008.01.004 · DOI
  43. Tarasov, 2007, Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest, Cell Cycle, 6, 1586, 10.4161/cc.6.13.4436 · DOI
  44. Thorgeirsson, 2002, Molecular pathogenesis of human hepatocellular carcinoma, Nat. Genet., 31, 339, 10.1038/ng0802-339 · DOI
  45. Ventura, 2009, MicroRNAs and cancer: short RNAs go a long way, Cell, 136, 586, 10.1016/j.cell.2009.02.005 · DOI
  46. Vermeulen, 2003, The cell cycle: a review of regulation, deregulation and therapeutic targets in cancer, Cell Prolif., 36, 131, 10.1046/j.1365-2184.2003.00266.x · DOI
  47. Visone, 2007, Specific microRNAs are downregulated in human thyroid anaplastic carcinomas, Oncogene, 26, 7590, 10.1038/sj.onc.1210564 · DOI
  48. Wakabayashi-Ito, 1994, Characterization of the regulatory elements in the promoter of the human elongation factor-1 alpha gene, J. Biol. Chem., 269, 29831, 10.1016/S0021-9258(18)43956-7 · DOI
  49. Wang, 2003, Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo, Gene Ther., 10, 2105, 10.1038/sj.gt.3302133 · DOI · Paper page
  50. Wienholds, 2005, MicroRNA expression in zebrafish embryonic development, Science, 309, 310, 10.1126/science.1114519 · DOI · Paper page
  51. Xi, 2006, Differentially regulated micro-RNAs and actively translated messenger RNA transcripts by tumor suppressor p53 in colon cancer, Clin. Cancer Res., 12, 2014, 10.1158/1078-0432.CCR-05-1853 · DOI
  52. Zhang, 2006, microRNAs exhibit high frequency genomic alterations in human cancer, Proc. Natl. Acad. Sci. USA, 103, 9136, 10.1073/pnas.0508889103 · DOI

Cited by

Sorted by citations

See all 1,452

Metadata

Authors
Kota, J., Chivukula, R. R., O'Donnell, K. A., Wentzel, E. A., Montgomery, C. L., Hwang, H.-W., Chang, T.-C., Vivekanandan, P., Torbenson, M., Clark, K. R., Mendell, J. R., & Mendell, J. T.
Venue
Cell
Publisher
Elsevier BV
Published
2009-06
Volume
137
Issue
6
Pages
1005-1017
ISSN
0092-8674
Cited by
1,452
References
13
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review