Nanotechnology, Inflammation and the Skin Barrier: Innovative Approaches for Skin Health and Cosmesis
Open accessAbstract
Dermatologic physiology and aesthetics are profoundly connected. Inflammatory stimuli abound in the environment, and have the potential to impact both the physiology and aesthetics of the integument. Inflammation results in a compromised epidermal barrier, impaired moisture retention, erythema, scale and pigment alteration. The advent of nanotechnology has introduced a variety of new approaches to preserving skin cosmesis in the face of inflammation. In this article, we review the architecture and physiology of the epidermal barrier, describe the pathological and aesthetic effects of inflammation, and report recent advances in the development of nanomaterials to offset the aesthetic impact of inflammation.
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Nanoparticulate barrier lotions are more effective than moisturizers with a high lipid content at preventing the skin from losing water, hence lowering the possibility of irritant hand eczema.
“Compared to moisturizers with a high lipid content, nanoparticulate barrier lotions are more effective at preventing the skin from losing water, hence lowering the possibility of irritant hand eczema [79].”
From AN OVERVIEW OF NEW TRENDS IN THE COSMETICS INDUSTRY (2025) · cites this paper as [79]
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- Authors
- Landriscina, A., Rosen, J., & Friedman, A.
- Affiliations
- Albert Einstein College of Medicine (US)
- Corresponding author
- Friedman, Adam
- ORCID
- Friedman, Adam
- Venue
- Cosmetics
- Publisher
- MDPI AG
- Published
- 2015-06-03
- Volume
- 2
- Issue
- 2
- Pages
- 177-186
- ISSN
- 2079-9284 (ISSN-L)
- OpenAlex
- W2170776140
- Cited by
- 20
- References
- 34
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 1 · 2022: 2 · 2021: 4 · 2020: 3 · 2019: 3 · 2018: 1 · 2017: 1 · 2016: 2
- FWCI
- 0.74
- Type
- journal article
- Language
- en
- Open access
- gold
- dx.doi.org
- Licence
- Locations
- Cosmetics (publishedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advancements in Transdermal Drug Delivery
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
- Keywords
- nanotechnology, skin inflammation, skin barrier, skin barrier function, nanomaterials, skin aesthetics, erythema, skin hydration, skin pigmentation, skin scaling
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