Diagnostic methods for evaluation of gastric motility-A mini review
Open accessAbstract
Gastric motility abnormalities are common in patients with disorders of gut-brain interaction, such as functional dyspepsia and gastroparesis. Accurate assessment of the gastric motility in these common disorders can help understand the underlying pathophysiology and guide effective treatment. A variety of clinically applicable diagnostic methods have been developed to objectively evaluate the presence of gastric dysmotility, including tests of gastric accommodation, antroduodenal motility, gastric emptying, and gastric myoelectrical activity. The aim of this mini review is to summarize the advances in clinically available diagnostic methods for evaluation of gastric motility and describe the advantages and disadvantages of each test.
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Since gastric myoelectrical abnormalities are not associated with the delay in gastric emptying, the delay may be a result of dysfunction in smooth muscle in coordination with the duodenum and antrum, or pylorospasm.
“Since gastric myoelectrical abnormalities are not associated with the delay in gastric emptying, it may be a result of dysfunction in smooth muscle in coordination with the duodenum and antrum, or pylorospasm (Wang et al., 2023).”
From Thyroid disorders and gastrointestinal dysmotility: an old association (2024) · cites this paper as Wang et al., 2023
Section 5.1 states that abnormal gastric slow waves are associated with delayed gastric emptying, directly contrary to the claim that myoelectrical abnormalities are not associated with it. The Introduction does identify gastric motor, pyloric, and duodenal dysfunction as possible contributors to delayed emptying, but it does not present them as alternatives established by an absence of electrical association. (LLM, conf=0.91)
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Pasricha, P. J., Grover, M., Yates, K. P., Abell, T. L., Bernard, C. E., Koch, K. L., McCallum, R. W., Sarosiek, I., Kuo, B., Bulat, R., et al. (2021) · Gastroenterology · doi:10.1053/j.gastro.2021.01.230 · Cited by 268 · see citing works
Self-citationSmall intestinal bacterial overgrowth in gastroparesis
George, N. S., Sankineni, A., & Parkman, H. P. (2014) · Digestive Diseases and Sciences · doi:10.1007/s10620-012-2426-7 · Cited by 61 · see citing works
Technique of Functional and Motility Test: How to Perform Antroduodenal Manometry
Patcharatrakul, T., & Gonlachanvit, S. (2013) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm.2013.19.3.395 · Cited by 58 · cited 1× · see citing works
“Antroduodenal manometry (ADM) allows simultaneous assessment of gastric and duodenal motility by measuring the frequency and characteristics of contraction patterns [50].”
BackgroundCarbone, F., De Buysscher, R., Van den Houte, K., Schol, J., Goelen, N., & Tack, J. (2022) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2021.03.023 · Cited by 55 · see citing works
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Cited by
Sorted by citations
Thyroid disorders and gastrointestinal dysmotility: an old association
Xu, G.-M., Hu, M.-X., Li, S.-Y., Ran, X., Zhang, H., & Ding, X.-F. (2024) · Frontiers in Physiology · doi:10.3389/fphys.2024.1389113 · Cited by 43 · see citing works
- Authors
- Wang, Y., Chen, J. D. Z., & Nojkov, B.
- Affiliations
- University of Michigan (US)
- Corresponding author
- Nojkov, Borko
- Venue
- Diagnostics
- Publisher
- MDPI AG
- Published
- 2023-02-20
- Volume
- 13
- Issue
- 4
- Pages
- 803
- ISSN
- 2075-4418 (ISSN-L)
- PMC
- PMC9955554
- OpenAlex
- W4321459629
- Cited by
- 31
- References
- 4
- Citations by year
- 2026: 11 · 2025: 13 · 2024: 6 · 2023: 1
- FWCI
- 1.82
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Diagnostics (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- NIH (R01DK131524, AT011380, UG3NS115108)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Gastroenterology › Gastroesophageal reflux and treatments
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal Bleeding Diagnosis and Treatment
- Keywords
- gastric motility, gastric dysmotility, functional dyspepsia, gastroparesis, gastric accommodation, antroduodenal motility, gastric emptying, gastric myoelectrical activity, gut-brain axis, diagnostic testing
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