Cited by 13Substance Abuse Treatment and OutcomesCannabis and Cannabinoid ResearchForensic Toxicology and Drug Analysis

Time trends in the co-use of cannabis and the misuse of tranquilizers, sedatives and sleeping pills among young adults in Spain between 2009 and 2015

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Palacios-Ceña, Domingo, Jiménez-Trujillo, Isabel, Hernández-Barrera, Valentín, Lima Florencio, Lidiane, Carrasco-Garrido, Pilar·2019·International Journal of Environmental Research and Public Health

Abstract

The aims of this study were: (a) to estimate time trends in the prevalence of the co-use of cannabis and other cannabis-based products (CBP) with the misuse of tranquilizers, sedatives, and sleeping pills (TSSp) between 2009 and 2015; and (b) to identify the factors associated with the probability of the co-use of CBP with TSSp misuse during this period among Spanish younger adults (15-34 years old). We analyzed data collected from the Spanish National Surveys on Alcohol and Other Drugs (EDADES) in 2009, 2011, 2013, and 2015. CBP co-use with TSSp misuse were the dependent variables. We also analyzed sociodemographic features, self-perceived health status, lifestyle habits, perceived health risk of consumption, and perceived availability of substance using logistic regression models. The prevalence of CBP co-use with TSSp misuse has decreased in Spain. The factors associated with co-use were a lack of education (OR 2.34), alcohol (OR 7.2), tobacco (OR 6.3) and other illicit psychoactive drug (OR 6.5) consumption, perceived non-health risk for the consumption of CBP and TSSp (OR 3.27), and perceived availability of CBP (OR 2.96). Our study identified several factors that appear to affect CBP and TSSp co-use in younger adults, with potential implications for healthcare providers.

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  • In young adults, low level of schooling and use of alcohol, tobacco, and illicit drugs correlate with the inappropriate use of sedatives and hypnotics.

    “In young adults, low level of schooling and use of alcohol, tobacco, and illicit drugs correlate with the inappropriate use of sedatives and hypnotics.”

    From Z-drug abuse and dependence: Clinical guideline of the Brazilian Academy of Neurology for diagnosis and management (2025) · cites this paper as [43]

    The Conclusions (page not provided) associate lack of education and use of alcohol, tobacco, and other illicit drugs with greater consumption among young adults. However, the study’s outcome is specifically the co-use of cannabis with misuse of tranquilizers, sedatives, and sleeping pills, not inappropriate use of sedatives and hypnotics on its own. (LLM, conf=0.87)

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Research works printed but not linked: 4

  1. [7]Patel J. Marwaha R. Cannabis Use Disorder StatPearls [Internet] StatPearls Publishing Treasure Island, FL, USA 2019 Available online: https://www.ncbi.nlm.nih.gov/books/NBK538131/ (accessed on 11 July 2019)
  2. [10]National Academies of Sciences, Engineering, and Medicine The Health Effects of Cannabis and Cannabinoids: Current State of Evidence and Recommendations for Research The National Academies Press Washington, DC, USA 2017 Available online: https://www.nap.edu/read/24625/chapter/1 (accessed on 11 July 2019) 28182367
  3. [16]Lipari R.N. Trends in Adolescent Substance Use and Perception of Risk from Substance Use The CBHSQ Report Substance Abuse and Mental Health Services Administration Rockville, MD, USA 2013 Available online: https://www.ncbi.nlm.nih.gov/books/NBK385059/ (accessed on 11 July 2019) 27656743
  4. [49]Preuss C.V. Kalava A. King K.C. Prescription of Controlled Substances: Benefits and Risks StatPearls [Internet] StatPearls Publishing Treasure Island, FL, USA 2019 Available online: https://www.ncbi.nlm.nih.gov/books/NBK537318/ (accessed on 11 July 2019) 30726003

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Authors
Palacios-Ceña, D., Jiménez-Trujillo, I., Hernández-Barrera, V., Lima Florencio, L., & Carrasco-Garrido, P.
Affiliations
  • Department of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Research Group of Humanities and Qualitative Research in Health Science of Universidad Rey Juan Carlos (Hum&QRinHS), Universidad Rey Juan Carlos, Alcorcón, 28922 Madrid, Spain
  • Preventive Medicine and Public Health Teaching and Research Unit, Health Sciences Faculty Universidad Rey Juan Carlos, Alcorcon, 28922 Madrid, Spain
  • Department of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Universidad Rey Juan Carlos, Alcorcón, 28922 Madrid, Spain
Venue
International Journal of Environmental Research and Public Health
Publisher
MDPI AG
Published
2019-09-15
Volume
16
Issue
18
Pages
3423
ISSN
1660-4601 (ISSN-L)
OpenAlex
W2973105575
Cited by
13
References
37
Citations by year
2026: 1 · 2025: 5 · 2024: 2 · 2023: 2 · 2021: 1 · 2020: 2
FWCI
0.57
Type
journal article
Language
en
Open access
Locations
  • International Journal of Environmental Research and Public Health (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • RePEc: Research Papers in Economics (submittedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
Funders
Instituto de Salud Carlos III (No. PI16/00691)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Pharmacology › Cannabis and Cannabinoid Research
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Forensic Toxicology and Drug Analysis
Keywords
cannabis co-use, cannabis-based products, polydrug use, young adults, temporal trends, substance use prevalence, alcohol consumption, tobacco use, health risk perception, sociodemographic factors, Spain
MeSH terms
Sleep Aids, Pharmaceutical, Adolescent, Adult, Female, Humans, Male, Marijuana Smoking, Self Concept, Spain, Tranquilizing Agents, Prevalence, Substance-Related Disorders, History, 21st Century, Young Adult

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