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Cited by 20Osteoarthritis Treatment and MechanismsMusculoskeletal pain and rehabilitationLower Extremity Biomechanics and Pathologies

Effectiveness of Exercise in Patients with Overweight or Obesity Suffering from Knee Osteoarthritis: A Systematic Review and Meta-Analysis

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Jurado-Castro, Jose Manuel, Muñoz-López, Mariano, Ledesma, Agustín Sánchez-Toledo, Ranchal-Sanchez, Antonio·2022·International Journal of Environmental Research and Public Health
DOI 10.3390/ijerph191710510PMC PMC9518463
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Abstract

Objectives: The main purpose of this study was to review the evidence about the effectiveness of exercise in patients with overweight or obesity suffering from knee osteoarthritis. Methods: Randomized clinical trials (RCTs) published between January 2002 and May 2022 were included. Results: A total of 64 articles were identified, of which six met the criteria for meta-analysis. The pain scale score was higher in the control group (mean difference 0.95; confidence interval 0.42–1.47; p < 0.001; I2 = 44%). The physical function scale (lower scores indicate lower levels of symptoms or physical disability) presented a higher score in the control group (mean difference 3.74; confidence interval 0.85–6.53; p < 0.05; I2 = 56%). Moreover, the intervention group achieved a greater distance (meters) walking in a 6 min interval (mean difference 38.18; confidence interval 20.01–56.35; p < 0.001; I2 = 0%). Conclusions: Exercise interventions seem effective in improving quality of life in people with overweight or obesity suffering from knee osteoarthritis, reducing pain and improving physical function.

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    Tamin, T. Z., & Clements, C. (2025) · Acta Medica Indonesiana

Authors
Jurado-Castro, J. M., Muñoz-López, M., Ledesma, A. S.-T., & Ranchal-Sanchez, A.
Affiliations
  • Metabolism and Investigation Unit, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Reina Sofia University Hospital, University of Cordoba, 14004 Cordoba, Spain
  • Universidad de Sevilla (ES)
  • Universidad Internacional de La Rioja (ES)
  • Department of Nursing, Pharmacology and Physiotherapy, Faculty of Medicine and Nursing, University of Cordoba, 14071 Cordoba, Spain
ORCID
Venue
International Journal of Environmental Research and Public Health
Publisher
MDPI AG
Published
2022-08-24
Volume
19
Issue
17
Pages
10510
ISSN
1660-4601 (ISSN-L)
DOI
10.3390/ijerph191710510
PMC
PMC9518463
OpenAlex
W4292869244
Cited by
20
References
3
Citations by year
2026: 6 · 2025: 6 · 2024: 5 · 2023: 3
FWCI
0.58
Type
journal article
Language
en
Open access
Licence
Locations
  • International Journal of Environmental Research and Public Health (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • RISalud Institutional Health Repository of Andalucía (submittedVersion, cc-by)
  • RePEc: Research Papers in Economics (submittedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
  • Universidad de Córdoba Insitutional Repository (Universidad de Córdoba) (submittedVersion, cc-by)
  • Re-Unir (International University of La Rioja) (submittedVersion, other-oa)
Funders
“Instituto de Seguridad y Bienestar Laboral”, Cordoba, Spain
Topics
  • Health Sciences › Medicine › Rheumatology › Osteoarthritis Treatment and Mechanisms
  • Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
  • Physical Sciences › Engineering › Biomedical Engineering › Lower Extremity Biomechanics and Pathologies
Keywords
knee osteoarthritis, obesity, overweight, exercise therapy, analgesia, physical function, walking distance, quality of life
MeSH terms
Humans, Obesity, Pain, Exercise, Osteoarthritis, Knee, Overweight

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