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Cited by 337

The DOI matches its Crossref record; 91 of the 91 references it cites were found in a registry or an index.

Smoking and Rheumatoid Arthritis

Open access
Chang, Kathleen, Yang, So, Kim, Seong, Han, Kyoung, Park, Se, Shin, Jae·2014·International Journal of Molecular Sciences

Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory disease caused by both genetic and environmental factors. Smoking has been implicated as one of the most important extrinsic risk factors for its development and severity. Recent developments have shed light on the pathophysiology of RA in smokers, including oxidative stress, inflammation, autoantibody formation and epigenetic changes. The association of smoking and the development of RA have been demonstrated through epidemiologic studies, as well as through in vivo and animal models of RA. With increased use of biological agents in addition to standard disease-modifying antirheumatic drugs (DMARDs), there has been interest in how smoking affects drug response in RA treatment. Recent evidence suggests the response and drug survival in people treated with anti-tumour necrosis factor (anti-TNF) therapy is poorer in heavy smokers, and possible immunological mechanisms for this effect are presented in the current paper.

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Crossref · 10.3390/ijms151222279

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Metadata

Authors
Chang, K., Yang, S., Kim, S., Han, K., Park, S., & Shin, J.
Venue
International Journal of Molecular Sciences
Publisher
MDPI AG
Published
2014-12-03
Volume
15
Issue
12
Pages
22279-22295
ISSN
1422-0067 (ISSN-L)
OpenAlex
W1998716086
Cited by
337
References
91
FWCI
5.32
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Smoking and Rheumatoid Arthritis. https://app.cochat.ai/papers/10.3390/ijms151222279
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Chang, K., Yang, S., Kim, S., Han, K., Park, S., & Shin, J. (2014). Smoking and Rheumatoid Arthritis. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms151222279

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.