The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Recent progress in the biology and physiology of sirtuins
Open accessAbstract
The sirtuins are a highly conserved family of NAD+-dependent enzymes that regulate lifespan in lower organisms. Recently, the mammalian sirtuins have been connected to an ever widening circle of activities that encompass cellular stress resistance, genomic stability, tumorigenesis and energy metabolism. Here we review the recent progress in sirtuin biology, the role these proteins have in various age-related diseases and the tantalizing notion that the activity of this family of enzymes somehow regulates how long we live.
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Cites
Resveratrol improves health and survival of mice on a high-calorie diet
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Cited by
HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression
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The growing landscape of lysine acetylation links metabolism and cell signalling
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Muscle wasting in disease: molecular mechanisms and promising therapies
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The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α
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Self-citation
Metadata
- Authors
- Finkel, T., Deng, C.-X., & Mostoslavsky, R.
- Venue
- Nature
- Published
- 2009-07
- Volume
- 460
- Issue
- 7255
- Pages
- 587-591
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- OpenAlex
- W1996395636
- Cited by
- 1,484
- References
- 29
- FWCI
- 71.35
- Type
- journal article
- Language
- en
- Open access
- green
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