The DOI matches its Crossref record; 87 of the 87 references it cites were found in a registry or an index.
Silk Fibroin-Based Nanoparticles for Drug Delivery
Open accessAbstract
Silk fibroin (SF) is a protein-based biomacromolecule with excellent biocompatibility, biodegradability and low immunogenicity. The development of SF-based nanoparticles for drug delivery have received considerable attention due to high binding capacity for various drugs, controlled drug release properties and mild preparation conditions. By adjusting the particle size, the chemical structure and properties, the modified or recombinant SF-based nanoparticles can be designed to improve the therapeutic efficiency of drugs encapsulated into these nanoparticles. Therefore, they can be used to deliver small molecule drugs (e.g., anti-cancer drugs), protein and growth factor drugs, gene drugs, etc. This paper reviews recent progress on SF-based nanoparticles, including chemical structure, properties, and preparation methods. In addition, the applications of SF-based nanoparticles as carriers for therapeutic drugs are also reviewed.
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Cites
Biodegradable polymeric nanoparticles based drug delivery systems
Kumari, A., Yadav, S. K., & Yadav, S. C. (2010) · Colloids and Surfaces B: Biointerfaces · doi:10.1016/j.colsurfb.2009.09.001 · Cited by 3,724
Factors affecting the clearance and biodistribution of polymeric nanoparticles
Alexis, F., Pridgen, E., Molnar, L. K., & Farokhzad, O. C. (2008) · Molecular Pharmaceutics · doi:10.1021/mp800051m · Cited by 3,699
Therapeutic Nanoparticles for Drug Delivery in Cancer
Cho, K., Wang, X., Nie, S., Chen, Z. (., & Shin, D. M. (2008) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-07-1441 · Cited by 2,920
Vepari, C., & Kaplan, D. L. (2007) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2007.05.013 · Cited by 2,561
Albumin-based nanoparticles as potential controlled release drug delivery systems
Elzoghby, A. O., Samy, W. M., & Elgindy, N. A. (2012) · Journal of Controlled Release · doi:10.1016/j.jconrel.2011.07.031 · Cited by 1,520
New Opportunities for an Ancient Material
Omenetto, F. G., & Kaplan, D. L. (2010) · Science · doi:10.1126/science.1188936 · Cited by 1,457
Nanoparticles as drug delivery systems
Wilczewska, A. Z., Niemirowicz, K., Markiewicz, K. H., & Car, H. (2012) · Pharmacological Reports · doi:10.1016/s1734-1140(12)70901-5 · Cited by 1,445
Silk fibroin biomaterials for tissue regenerations
Kundu, B., Rajkhowa, R., Kundu, S. C., & Wang, X. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.09.043 · Cited by 1,391
Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles
Pinto Reis, C., Neufeld, R. J., Ribeiro, & Veiga, F. (2006) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2005.12.003 · Cited by 1,354
Electrospraying route to nanotechnology: An overview
Jaworek, A., & Sobczyk, A. T. (2008) · Journal of Electrostatics · doi:10.1016/j.elstat.2007.10.001 · Cited by 963
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Li, M., You, J., Qin, Q., Liu, M., Yang, Y., Jia, K., Zhang, Y., & Zhou, Y. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032660 · Cited by 64
Gulati, S., Ansari, N., Moriya, Y., Joshi, K., Prasad, D., Sajwan, G., Shukla, S., Kumar, S., & Varma, R. S. (2024) · Journal of Materials Chemistry B · doi:10.1039/d4tb00599f · Cited by 52
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Zheng, W., & Xu, C.-H. (2023) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.3c00028 · Cited by 32
Metadata
- Authors
- Zhao, Z., Li, Y., & Xie, M.-B.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2015-03-04
- Volume
- 16
- Issue
- 3
- Pages
- 4880-4903
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W1977256998
- Cited by
- 332
- References
- 87
- FWCI
- 7.54
- Type
- journal article
- Language
- en
- Open access
- gold
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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