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Cited by 377

The DOI matches its Crossref record; 382 of the 382 references it cites were found in a registry or an index.

Galectin-3: One Molecule for an Alphabet of Diseases, from A to Z

Open access
Sciacchitano, Salvatore, Lavra, Luca, Morgante, Alessandra, Ulivieri, Alessandra, Magi, Fiorenza, De Francesco, Gian, Bellotti, Carlo, Salehi, Leila, Ricci, Alberto·2018·International Journal of Molecular Sciences
DOI 10.3390/ijms19020379
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Abstract

Galectin-3 (Gal-3) regulates basic cellular functions such as cell–cell and cell–matrix interactions, growth, proliferation, differentiation, and inflammation. It is not surprising, therefore, that this protein is involved in the pathogenesis of many relevant human diseases, including cancer, fibrosis, chronic inflammation and scarring affecting many different tissues. The papers published in the literature have progressively increased in number during the last decades, testifying the great interest given to this protein by numerous researchers involved in many different clinical contexts. Considering the crucial role exerted by Gal-3 in many different clinical conditions, Gal-3 is emerging as a new diagnostic, prognostic biomarker and as a new promising therapeutic target. The current review aims to extensively examine the studies published so far on the role of Gal-3 in all the clinical conditions and diseases, listed in alphabetical order, where it was analyzed.

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Metadata

Authors
Sciacchitano, S., Lavra, L., Morgante, A., Ulivieri, A., Magi, F., De Francesco, G., Bellotti, C., Salehi, L., & Ricci, A.
Venue
International Journal of Molecular Sciences
Publisher
MDPI AG
Published
2018-01-26
Volume
19
Issue
2
Pages
379
ISSN
1422-0067 (ISSN-L)
DOI
10.3390/ijms19020379
OpenAlex
W2789752648
Cited by
377
References
382
FWCI
11.51
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Galectin-3: One Molecule for an Alphabet of Diseases, from A to Z. https://app.cochat.ai/papers/10.3390/ijms19020379
The paper
Sciacchitano, S., Lavra, L., Morgante, A., Ulivieri, A., Magi, F., De Francesco, G., Bellotti, C., Salehi, L., & Ricci, A. (2018). Galectin-3: One Molecule for an Alphabet of Diseases, from A to Z. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms19020379

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.