The DOI matches its Crossref record; 83 of the 83 references it cites were found in a registry or an index.
The Need for Multi-Omics Biomarker Signatures in Precision Medicine
Open accessAbstract
Recent advances in omics technologies have led to unprecedented efforts characterizing the molecular changes that underlie the development and progression of a wide array of complex human diseases, including cancer. As a result, multi-omics analyses—which take advantage of these technologies in genomics, transcriptomics, epigenomics, proteomics, metabolomics, and other omics areas—have been proposed and heralded as the key to advancing precision medicine in the clinic. In the field of precision oncology, genomics approaches, and, more recently, other omics analyses have helped reveal several key mechanisms in cancer development, treatment resistance, and recurrence risk, and several of these findings have been implemented in clinical oncology to help guide treatment decisions. However, truly integrated multi-omics analyses have not been applied widely, preventing further advances in precision medicine. Additional efforts are needed to develop the analytical infrastructure necessary to generate, analyze, and annotate multi-omics data effectively to inform precision medicine-based decision-making.
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Cited by
Applications of multi‐omics analysis in human diseases
Chen, C., Wang, J., Pan, D., Wang, X., Xu, Y., Yan, J., Wang, L., Yang, X., Yang, M., & Liu, G. (2023) · MedComm · doi:10.1002/mco2.315 · Cited by 545
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Long-term cancer survival prediction using multimodal deep learning
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Integrated multi-omics analysis of ovarian cancer using variational autoencoders
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Phenomic studies on diseases: potential and challenges
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Metadata
- Authors
- Olivier, M., Asmis, R., Hawkins, G. A., Howard, T. D., & Cox, L. A.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2019-09-26
- Volume
- 20
- Issue
- 19
- Pages
- 4781
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W2976952765
- Cited by
- 499
- References
- 83
- FWCI
- 14.61
- Type
- journal article
- Language
- en
- Open access
- gold
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