Integrative Clinical Genomics of Advanced Prostate Cancer

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data

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Integrative genomics viewer

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Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

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Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

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Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

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Mutational heterogeneity in cancer and the search for new cancer-associated genes

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Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

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Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy

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Abiraterone and Increased Survival in Metastatic Prostate Cancer

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Recurrent Fusion of <i>TMPRSS2</i> and ETS Transcription Factor Genes in Prostate Cancer

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Integrative Genomic Profiling of Human Prostate Cancer

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Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from <i>BRCA</i> Mutation Carriers

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A census of human cancer genes

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Discovery and saturation analysis of cancer genes across 21 tumour types

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The Molecular Taxonomy of Primary Prostate Cancer

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Enzalutamide in Metastatic Prostate Cancer before Chemotherapy

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Abiraterone in Metastatic Prostate Cancer without Previous Chemotherapy

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AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer

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The mutational landscape of lethal castration-resistant prostate cancer

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Circular binary segmentation for the analysis of array-based DNA copy number data

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The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study

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Olaparib Monotherapy in Patients With Advanced Cancer and a Germline BRCA1/2 Mutation

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Organoid Cultures Derived from Patients with Advanced Prostate Cancer

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Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

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The evolutionary history of lethal metastatic prostate cancer

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Punctuated Evolution of Prostate Cancer Genomes

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Mutation of the Androgen-Receptor Gene in Metastatic Androgen-Independent Prostate Cancer

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The genomic complexity of primary human prostate cancer

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Recurrent R-spondin fusions in colon cancer

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Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer

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Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

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Germline BRCA Mutations Are Associated With Higher Risk of Nodal Involvement, Distant Metastasis, and Poor Survival Outcomes in Prostate Cancer

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Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974

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TopHat-Fusion: an algorithm for discovery of novel fusion transcripts

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Integrated genomic characterization of adrenocortical carcinoma

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Personalized Oncology Through Integrative High-Throughput Sequencing: A Pilot Study

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Somatic ERCC2 Mutations Correlate with Cisplatin Sensitivity in Muscle-Invasive Urothelial Carcinoma

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Proposed Morphologic Classification of Prostate Cancer With Neuroendocrine Differentiation

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PTEN-deficient cancers depend on PIK3CB

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Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine

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RNF43 is frequently mutated in colorectal and endometrial cancers

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Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

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Targeted Next-generation Sequencing of Advanced Prostate Cancer Identifies Potential Therapeutic Targets and Disease Heterogeneity

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Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

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Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer

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Beta-catenin mutations in human prostate cancer.

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Copy number alteration burden predicts prostate cancer relapse

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Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study

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Tumor clone dynamics in lethal prostate cancer

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The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo

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Complex MSH2 and MSH6 mutations in hypermutated microsatellite unstable advanced prostate cancer

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Feedback Suppression of PI3Kα Signaling in PTEN-Mutated Tumors Is Relieved by Selective Inhibition of PI3Kβ

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Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover

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Discovery of non-ETS gene fusions in human prostate cancer using next-generation RNA sequencingPreprint

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Targeting cell cycle and hormone receptor pathways in cancer

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Characterization of KRAS Rearrangements in Metastatic Prostate Cancer

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Detection of Somatic Copy Number Alterations in Cancer Using Targeted Exome Capture Sequencing

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Characterization of Bone Metastases from Rapid Autopsies of Prostate Cancer Patients

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PLZF, a Tumor Suppressor Genetically Lost in Metastatic Castration-Resistant Prostate Cancer, Is a Mediator of Resistance to Androgen Deprivation Therapy

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PLZF regulates Pbx1 transcription and Pbx1–HoxC8 complex leads to androgen-independent prostate cancer proliferation

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PLZF Mediates the PTEN/AKT/FOXO3a Signaling in Suppression of Prostate Tumorigenesis

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Successful whole-exome sequencing from a prostate cancer bone metastasis biopsy

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Antitumour Activity of the Parp Inhibitor Olaparib in Unselected Sporadic Castration-Resistant Prostate Cancer (Crpc) in the Toparp Trial

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The Molecular Taxonomy of Primary Prostate Cancer

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Olaparib for Metastatic Castration-Resistant Prostate Cancer

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DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer

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Metastatic colonization by circulating tumour cells

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The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs—Part B: Prostate and Bladder Tumours

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Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer

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The Landscape of Circular RNA in Cancer

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