Ionizing Radiation as a Source of Oxidative Stress—The Protective Role of Melatonin and Vitamin D

Oxidative stress: a concept in redox biology and medicine

Sies, H. (2015) · Redox Biology · doi:10.1016/j.redox.2015.01.002 · Cited by 3,208

The role of antioxidants in the chemistry of oxidative stress: A review

Pisoschi, A. M., & Pop, A. (2015) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2015.04.040 · Cited by 2,963

Oxidative stress and the amyloid beta peptide in Alzheimer’s disease

Cheignon, C., Tomas, M., Bonnefont-Rousselot, D., Faller, P., Hureau, C., & Collin, F. (2018) · Redox Biology · doi:10.1016/j.redox.2017.10.014 · Cited by 2,185

Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects

Christakos, S., Dhawan, P., Verstuyf, A., Verlinden, L., & Carmeliet, G. (2015) · Physiological Reviews · doi:10.1152/physrev.00014.2015 · Cited by 2,105

Reactive Oxygen Species in Metabolic and Inflammatory Signaling

Forrester, S. J., Kikuchi, D. S., Hernandes, M. S., Xu, Q., & Griendling, K. K. (2018) · Circulation Research · doi:10.1161/circresaha.117.311401 · Cited by 2,081

Melatonin as an antioxidant: under promises but over delivers

Reiter, R. J., Mayo, J. C., Tan, D. X., Sainz, R. M., Alatorre-Jiménez, M. A., & Qin, L. (2016) · Journal of Pineal Research · doi:10.1111/jpi.12360 · Cited by 1,777

ISOLATION OF MELATONIN, THE PINEAL GLAND FACTOR THAT LIGHTENS MELANOCYTES 1

Lerner, A. B., Case, J. D., TAKAHASHI, Y., Lee, T. H., & Mori, W. (1958) · Journal of the American Chemical Society · doi:10.1021/ja01543a060 · Cited by 1,759

Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury

Azzam, E. I., Jay‐Gerin, J., & Pain, D. (2011) · Cancer Letters · doi:10.1016/j.canlet.2011.12.012 · Cited by 1,688

The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention

Holick, M. F. (2017) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-017-9424-1 · Cited by 1,641

Reactive Oxygen Species, Toxicity, Oxidative Stress, and Antioxidants: Chronic Diseases and Aging

Jomova, K., Raptova, R., Alomar, S. Y., Alwasel, S. H., Nepovimova, E., Kuca, K., & Valko, M. (2023) · Archives of Toxicology · doi:10.1007/s00204-023-03562-9 · Cited by 2,638

Molecular pathways associated with oxidative stress and their potential applications in radiotherapy (Review)

Liu, R., Bian, Y., Liu, L., Liu, L., Liu, X., & Ma, S. (2022) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2022.5121 · Cited by 125

The Effect of β-Carotene, Tocopherols and Ascorbic Acid as Anti-Oxidant Molecules on Human and Animal In Vitro/In Vivo Studies: A Review of Research Design and Analytical Techniques Used

Miazek, K., Beton-Mysur, K., Śliwińska, A., & Brożek-Płuska, B. (2022) · Biomolecules · doi:10.3390/biom12081087 · Cited by 117

Dual sources of melatonin and evidence for different primary functions

Reiter, R. J., Sharma, R., Tan, D. X., Chuffa, L. G. D. A., da Silva, D. G. H., Slominski, A. T., Steinbrink, K., & Kleszczyński, K. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1414463 · Cited by 83

Nuclear and Radiological Emergencies: Biological Effects, Countermeasures and Biodosimetry

Obrador, E., Palmer, R. S., Villaescusa, J. I., Gallego, E., Pellicer, B., Estrela, J. M., & Montoro, A. (2022) · Antioxidants · doi:10.3390/antiox11061098 · Cited by 80

Oxidative Stress-Driven Cellular Senescence: Mechanistic Crosstalk and Therapeutic Horizons

Stojanović, B., Jovanovic, I., Stojanovic, M. D., Stojanović, B., Kovačević, V., Radosavljević, I., Jovanović, D., Kovačević, M. M., Zornić, N., Arsić, A. A., et al. (2025) · Antioxidants · doi:10.3390/antiox14080987 · Cited by 89

A comprehensive review of sensors of radiation‐induced damage, radiation‐induced proximal events, and cell death

Saini, S., & Gurung, P. (2024) · Immunological Reviews · doi:10.1111/imr.13409 · Cited by 84

The Role of Oxidative Stress Enhanced by Adiposity in Cardiometabolic Diseases

Świątkiewicz, I., Wróblewski, M., Nuszkiewicz, J., Sutkowy, P., Wróblewska, J., & Woźniak, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076382 · Cited by 81

Exploring Natural Products as Radioprotective Agents for Cancer Therapy: Mechanisms, Challenges, and Opportunities

Zhang, Y., Huang, Y., Li, Z., Wu, H., Zou, B., & Xu, Y. H. (2023) · Cancers · doi:10.3390/cancers15143585 · Cited by 70

Evolutionary formation of melatonin and vitamin D in early life forms: insects take centre stage

Kim, T., Slominski, R. M., Pyza, E., Kleszczyński, K., Tuckey, R. C., Reiter, R. J., Holick, M. F., & Slominski, A. T. (2024) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.13091 · Cited by 68

The Intertwined Roles of Oxidative Stress and Endoplasmic Reticulum Stress in Glaucoma

Hurley, D. J., Normile, C., Irnaten, M., & O'Brien, C. J. (2022) · Antioxidants · doi:10.3390/antiox11050886 · Cited by 64

Molecular Hydrogen as a Potential Clinically Applicable Radioprotective Agent

Hirano, S., Ichikawa, Y., Sato, B., Yamamoto, H., Takefuji, Y., & Satoh, F. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22094566 · Cited by 51

Radiation-induced liver disease: beyond DNA damage

Zhou, Y. J., Tang, Y., Liu, S. J., Zeng, P. H., Qu, L., Jing, Q., & Yin, W. J. (2022) · Cell Cycle · doi:10.1080/15384101.2022.2131163 · Cited by 50

Melatonin and the Skin: Current Progress and Perspectives for Human Health

Slominski, A. T., Kim, T., Janjetović, Z., Slominski, R. M., Ganguli‐Indra, G., Athar, M., Indra, A. K., Reiter, R. J., & Kleszczyński, K. (2025) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2024.11.012 · Cited by 46

Oxidative stress and radioiodine treatment of differentiated thyroid cancer

Buczyńska, A., Sidorkiewicz, I., Rogucki, M., Siewko, K., Adamska, A., Kościuszko, M., Maliszewska, K., Kozłowska, G., Szumowski, P., Myśliwiec, J., et al. (2021) · Scientific Reports · doi:10.1038/s41598-021-96637-5 · Cited by 37

Biomimetic Prussian blue nanozymes with enhanced bone marrow-targeting for treatment of radiation-induced hematopoietic injury

Zhang, B., Chen, G., Wu, X., Li, Y., Xiao, Y., Li, J., He, L., Li, Y., Wang, S., Zhao, J., et al. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2022.121980 · Cited by 38

Crosstalk between Oxidative Stress and Inflammation Induced by Ionizing Radiation in Healthy and Cancerous Cells

Mohammadgholi, M., & Hosseinimehr, S. J. (2023) · Current Medicinal Chemistry · doi:10.2174/0929867330666230407104208 · Cited by 42

Sustained oxidative stress instigates differentiation of cancer stem cells into tumor endothelial cells: Pentose phosphate pathway, reactive oxygen species and autophagy crosstalk

Movahed, Z. G., Yarani, R., Mohammadi, P., & Mansouri, K. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111643 · Cited by 33

Natural Guardians: Natural Compounds as Radioprotectors in Cancer Therapy

Stasiłowicz-Krzemień, A., Gościniak, A., Formanowicz, D., & Cielecka‐Piontek, J. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25136937 · Cited by 37

Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Perspectives

Anwar, S., Alharbi, H. O. A., Babiker, A. Y., & Rahmani, A. H. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27062681 · Cited by 40

Radioprotectors, Radiomitigators, and Radiosensitizers

Montoro, A., Obrador, E., Mistry, D., Forte, G. I., Bravatà, V., Minafra, L., Calvaruso, M., Cammarata, F. P., Falk, M., Schettino, G., et al. (2023) · Springer eBooks · doi:10.1007/978-3-031-18810-7_11 · Cited by 29

The hydrogen storage nanomaterial MgH 2 improves irradiation-induced male fertility impairment by suppressing oxidative stress

Ma, J., Dong, S., Lu, H., Chen, Z., Yu, H., Sun, X., Peng, R., Li, W., Wang, S., Jiang, Q., et al. (2022) · Biomaterials Research · doi:10.1186/s40824-022-00266-6 · Cited by 27

Impact of radiation therapy on healthy tissues

Chargari, C., Rassy, E., Hélissey, C., Achkar, S., François, S., & Deutsch, É. (2022) · International review of cytology · doi:10.1016/bs.ircmb.2022.11.006 · Cited by 26

Suppression of inflammatory cascades via novel cinnamic acid nanoparticles in acute hepatitis rat model

Ibrahim, E. A., Moawed, F. S., & Moustafa, E. M. (2020) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2020.108658 · Cited by 25

Vitamin D Receptor Protects against Radiation-Induced Intestinal Injury in Mice via Inhibition of Intestinal Crypt Stem/Progenitor Cell Apoptosis

Li, W., Lin, Y., Luo, Y., Wang, Y., Lu, Y., Li, Y., & Guo, H. (2021) · Nutrients · doi:10.3390/nu13092910 · Cited by 27

8-OxodG: A Potential Biomarker for Chronic Oxidative Stress Induced by High-LET Radiation

Kumar, K., Fornace, A. J., & Suman, S. (2024) · DNA · doi:10.3390/dna4030015 · Cited by 24

Comparison of the Effects of Resveratrol and Its Derivatives on the Radiation Response of MCF-7 Breast Cancer Cells

Komorowska, D., Gajewska, A., Hikisz, P., Bartosz, G., & Rodacka, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22179511 · Cited by 23

Association between Vitamin D Supplements, Oxidative Stress Biomarkers, and Hyperbaric Therapy in Patients with Sudden Sensorineural Hearing Loss

Paprocki, J., Sutkowy, P., Piechocki, J., & Woźniak, A. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/8895323 · Cited by 22

Assessment of thyroid gland hormones and ultrasonographic abnormalities in medical staff occupationally exposed to ionizing radiation

El-Benhawy, S. A., Fahmy, E. I., Mahdy, S. M., Khedr, G. H., Sarhan, A. S., Nafady, M. H., Selim, Y. A. Y., Salem, T. M., Abu‐Samra, N., & Khadry, H. A. E. (2022) · BMC Endocrine Disorders · doi:10.1186/s12902-022-01196-z · Cited by 20

Ionizing Radiation, Antioxidant Response and Oxidative Damage: Radiomodulators

Obrador, E., & Montoro, A. (2023) · Antioxidants · doi:10.3390/antiox12061219 · Cited by 20

Fullerenol C60(OH)36 Protects the Antioxidant Enzymes in Human Erythrocytes against Oxidative Damage Induced by High-Energy Electrons

Grębowski, J., Kaźmierska, P., Cichoń, N., Konarska, A., Wolszczak, M., & Litwinienko, G. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231810939 · Cited by 21

Utility of melatonin in mitigating ionizing radiation-induced testis injury through synergistic interdependence of its biological properties

Amer, M. E., Othman, A. I., Abozaid, H. M., & El-Missiry, M. A. (2022) · Biological Research · doi:10.1186/s40659-022-00401-6 · Cited by 19

Promising Functions of Novel Vitamin D Derivatives as Cosmetics: A New Fountain of Youth in Skin Aging and Skin Protection

Janjetović, Z., & Slominski, A. T. (2024) · Cosmetics · doi:10.3390/cosmetics11020037 · Cited by 23

Reactive oxygen species in cell signaling and cell death: A redox perspective on metabolic and inflammatory disorders

Deepak, K., Shee, M., Roy, P., & Mandal, M. (2026) · Cell Death · doi:10.1016/j.celld.2026.100009 · Cited by 19

Nrf2-regulated antioxidant response ameliorating ionizing radiation-induced damages explored throughin vitroand molecular dynamics simulations

Gnanasekaran, T. S., Ashok, A. K., Rao, S. J. A., Gollapalli, P., Vishakh, R., Kumari, S., & Chaudhury, N. K. (2022) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2022.2137245 · Cited by 18

Recent Advances in Plasma-Based Cancer Treatments: Approaching Clinical Translation through an Intracellular View

Alizadeh, E., & Ptasińska, S. (2021) · Biophysica · doi:10.3390/biophysica1010005 · Cited by 18

Perspectives and Advances of Nonthermal Plasma Technology in Cancers

Trimukhe, A. M., Pandiyaraj, K. N., Patekar, M., Miller, V., & Deshmukh, R. R. (2022) · IEEE Transactions on Plasma Science · doi:10.1109/tps.2022.3182717 · Cited by 17

Prenatal Screening of Trisomy 21: Could Oxidative Stress Markers Play a Role?

Buczyńska, A., Sidorkiewicz, I., Ławicki, S., Kretowski, A. J., & Zbucka-Krętowska, M. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10112382 · Cited by 16

Ataxia-telangiectasia mutated plays an important role in cerebellar integrity and functionality

Mitiagin, Y., & Barzilai, A. (2022) · Neural Regeneration Research · doi:10.4103/1673-5374.350194 · Cited by 16

Carrier‐based delivery system of phytohormones in plants: stepping outside of the ordinary

Tiwari, K., Tripathi, S., Mahra, S., Mathew, S., Rana, S., Tripathi, D. K., & Sharma, S. (2024) · Physiologia Plantarum · doi:10.1111/ppl.14387 · Cited by 15

Cosmic Ionizing Radiation: A DNA Damaging Agent That May Underly Excess Cancer in Flight Crews

Toprani, S. M., Scheibler, C., Mordukhovich, I., McNeely, E., & Nagel, Z. D. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25147670 · Cited by 19

Modulation of autophagy by melatonin via sirtuins in stroke: From mechanisms to therapies

Azedi, F., Tavakol, S., Ketabforoush, A. H. M. E., Khazaei, G., Bakhtazad, A., Mousavizadeh‬, K., & Joghataei, M. T. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120870 · Cited by 16

The levels of oxidative stress in a combination of stress factors

Ilderbayev, O. Z., Okassova, A. K., Rakhyzhanova, S., Ilderbayeva, G. O., & Zhazykbayeva, L. (2022) · Journal of Medicine and Life · doi:10.25122/jml-2021-0060 · Cited by 14

Protective role of melatonin against radiation-induced disruptions in behavior rhythm of zebrafish (danio rerio)

Zhao, W., Yao, J., Liu, Y., Mao, L., He, C., & Long, D. (2024) · Aquatic Toxicology · doi:10.1016/j.aquatox.2024.107106 · Cited by 13

Melatonin and vitamin D as potential synergistic adjuvants for cancer therapy (Review)

Reiter, R. J., Chuffa, L. G. D. A., Simão, V. A., Giménez, V. M. M., Heras, N. D. L., Spandidos, D. A., & Manucha, W. A. (2024) · International Journal of Oncology · doi:10.3892/ijo.2024.5702 · Cited by 15

Effect of Oral Vitamin D3 on Dental Caries: An In-Vivo and In-Vitro Study

Al-Jubori, S. H., Al-Murad, M., & Al-Mashhadane, F. (2022) · Cureus · doi:10.7759/cureus.25360 · Cited by 13

Mitochondrial-targeting fluorescent small molecule IR-780 alleviates radiation-induced brain injury

Zhang, C., Zheng, J., Chen, W., Yang, W., Tan, X., Fan, X., Shen, G., Qu, L., Chen, Z., & Shi, C. (2023) · Brain Research · doi:10.1016/j.brainres.2023.148285 · Cited by 11

Receptor-Mediated and Receptor-Independent Actions of Melatonin in Vertebrates

Hattori, A., & Suzuki, N. (2024) · ZOOLOGICAL SCIENCE · doi:10.2108/zs230057 · Cited by 13

Connection between Radiation-Regulating Functions of Natural Products and miRNAs Targeting Radiomodulation and Exosome Biogenesis

Tang, J.-Y., Chuang, Y.-T., Shiau, J., Yen, C., Chang, F., Tsai, Y., Farooqı, A. A., & Chang, H. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241512449 · Cited by 11

Advances in cheese safety and quality: harnessing irradiation technologies for enhanced preservation

Akacha, B. B., Madureira, J., Verde, S. C., Mekinić, I. G., Kačániová, M., Čmiková, N., Kukula-Koch, W. A., Koch, W., Orhan, İ. E., Saad, R. B., et al. (2025) · Journal of Food Science and Technology · doi:10.1007/s13197-024-06190-y · Cited by 10

Glycyrrhizin ameliorating sterile inflammation induced by low-dose radiation exposure

Kim, H. C., Oh, H.-W., You, J. S., & Chung, Y. E. (2021) · Scientific Reports · doi:10.1038/s41598-021-97800-8 · Cited by 11

Diesel exhaust particulate matter induces GC-1 spg cells oxidative stress by KEAP1-NRF2 pathway and inhibition of ATP5α1 S-sulfhydration

Shi, J., Tian, F., Ren, J., Li, R., Yang, M., & Li, W. (2024) · Food and Chemical Toxicology · doi:10.1016/j.fct.2024.114746 · Cited by 9

Hesperidin attenuates radiation-induced ovarian failure in rats: Emphasis on TLR-4/NF-ĸB signaling pathway

Mohamed, D. H., Said, R. S., Kassem, D. H., Gad, A. M., El‐Demerdash, E., & Mantawy, E. M. (2024) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2024.117111 · Cited by 9

Demystifying the management of cancer through smart nano-biomedicine via regulation of reactive oxygen species

Mishra, A. P., Kumar, R., Harilal, S., Nigam, M., Datta, D., Singh, S. K., Waranuch, N., & Chittasupho, C. (2024) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-024-03469-x · Cited by 9

Engineering cuttlefish melanin nanoparticles: A dual-action therapy for acute radiation syndrome and combined radiation-wound injuries via regulating Bcl-2 family proteins and caspases in the apoptotic process

Zhao, Z., Hu, B., Zhang, D., Cui, X., Ding, W., Wang, T., Wang, J., Guo, Z., Zhou, Y., Wang, S., et al. (2025) · Chemical Engineering Journal · doi:10.1016/j.cej.2025.162108 · Cited by 9

Pharmacological and therapeutic innovation to mitigate radiation-induced cognitive decline (RICD) in brain tumor patients

Raj, J. A. T., Shah, J., Ghanekar, S., John, G., Goda, J. S., & Chatterjee, A. (2025) · Cancer Letters · doi:10.1016/j.canlet.2025.217700 · Cited by 9

Insights Into Antioxidant Strategies to Counteract Radiation-Induced Male Infertility

Spadella, M. A., Silva, E. J. R., Chies, A. B., & de Almeida, L. A. (2023) · Antioxidants and Redox Signaling · doi:10.1089/ars.2023.0282 · Cited by 9

Mitochondrial dysfunction as a key player in aggravating periodontitis among diabetic patients: review of the current scope of knowledge

Wadan, A. S., Moshref, A. S., Emam, A. M., Bakry, Y. G., Khalil, B. O., Chaurasia, A., Ibrahim, R. A. H., Badawy, T., & Mehanny, S. (2025) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-025-04025-x · Cited by 8

The Role of Vitamins in Pediatric Urinary Tract Infection: Mechanisms and Integrative Strategies

Wróblewska, J., Złocińska, H., Wróblewski, M., Nuszkiewicz, J., & Woźniak, A. (2025) · Biomolecules · doi:10.3390/biom15040566 · Cited by 8

The Alleviating Effect of Herniarin Against Ionizing Radiation-Induced Genotoxicity and Cytotoxicity in Human Peripheral Blood Lymphocytes

Molazadeh, M., Fares, E. A., Sanikidze, T. V., Kalmakhelidze, S., TOPURIA, D., Mansi, L., & Kitson, S. L. (2021) · Current Radiopharmaceuticals · doi:10.2174/1874471014666211012104808 · Cited by 8

Antioxidants Hydroxytyrosol and Thioredoxin-Mimetic Peptide CB3 Protect Irradiated Normal Tissue Cells

Borrmann, K., Troschel, F. M., Brücksken, K. A., Espinoza‐Sánchez, N. A., Rezaei, M., Eder, K., Kemper, B., Eich, H. T., & Greve, B. (2024) · Antioxidants · doi:10.3390/antiox13080961 · Cited by 6

Neuroprotective effects of saxagliptin against radiation-induced cognitive impairment: Insights on Akt/CREB/SIRT1/BDNF signaling pathway

Abdelhamid, A. H., Mantawy, E. M., Said, R. S., & El‐Demerdash, E. (2024) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2024.116994 · Cited by 6

Radiation Damage in Biomolecules and Cells

Carante, M. P., & Ballarini, F. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21218188 · Cited by 6

The effects of sustained and diel-cycling hypoxia on high-latitude fish Phoxinus lagowskii

Wang, S., Sun, M., Ning, Z., Chen, Y., Zhou, H., & Mu, W. (2023) · Comparative Biochemistry and Physiology Part D Genomics and Proteomics · doi:10.1016/j.cbd.2023.101059 · Cited by 6

Melatonin ameliorates high glucose-induced autophagy in Schwann cells.

Salem, H. M. A., Chok, K. C., Koh, R. Y., Ng, P. Y., Tiong, Y. L., & Chye, S. M. (2023) · PubMed Central · Cited by 6

Chronic Radium-226 toxicity to and oxidative stress in the aquatic invertebrate Chironomus dilutus

Lacroix-Durand, C., Janz, D. M., & Liber, K. (2024) · Toxicology Research · doi:10.1093/toxres/tfaf001 · Cited by 5

Melatonin As An Antioxidant Agent In Disease Prevention: A Biochemical Focus

Akhzari, M., Barazesh, M., & Jalili, S. (2022) · Letters in Organic Chemistry · doi:10.2174/1570178619666220325124451 · Cited by 6

Synthetic and Natural Radioprotective Agents: Recent Status and their Underlying Mechanism of Action

Mishra, J., Poonia, N., Lather, V., Nishad, D. K., & Pandita, D. (2024) · Current Pharmaceutical Biotechnology · doi:10.2174/0113892010293722240522071042 · Cited by 5

Advancements in radiobiology techniques and applications for personalized radiation therapy in nuclear medicine

He, Y., Rusho, M. A., Menon, S. V., Kaur, M., Jabir, M. S., Jawad, S. F., Hasan, T. F., Najm, M. A. A., Jawad, M. A., & Khelief, A. J. (2024) · Journal of Radioanalytical and Nuclear Chemistry · doi:10.1007/s10967-024-09804-z · Cited by 5

Assessing the Antimicrobial, Antioxidant and Anti-inflammatory Potential of Ethanolic Extract of Irradiated Rosa canina L. Fruits

Moustafa, E. M., Araby, E., & Elbahkery, A. L. (2021) · Egyptian Journal of Radiation Sciences and Applications · doi:10.21608/ejrsa.2021.105897.1124 · Cited by 5

Radioprotective Mechanisms of Arbutin: A Systematic Review

Sadeghinezhad, S., Khodamoradi, E., Diojan, L., Taeb, S., & Najafi, M. (2022) · Current Drug Research Reviews · doi:10.2174/2589977514666220321114415 · Cited by 5

Neuroprotective effects of alpha-lipoic acid on radiation-induced brainstem injury in rats

Motallebzadeh, E., Aghighi, F., Vakili, Z., Talaei, S. A., & Mohseni, M. (2023) · Research in Pharmaceutical Sciences · doi:10.4103/1735-5362.367798 · Cited by 6

In Vitro Evaluation of the Antioxidant Capacity of 3,3-Disubstituted-3H-benzofuran-2-one Derivatives in a Cellular Model of Neurodegeneration

Scibetta, S., Miceli, M., Iuliano, M., Stefanuto, L., Carbone, E., Piscopo, P., Petrozza, V., Romeo, G., Mangino, G., Calogero, A., et al. (2024) · Life · doi:10.3390/life14040422 · Cited by 5

Valorization of Human Hair and Its Derivatives in Tissue Engineering: A Review

Vitus, V., Ibrahim, F., & Zaman, W. S. W. K. (2022) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2021.022333 · Cited by 5

Effect of simultaneous exposure to inhalational anesthetics and radiation on the adaptive response in operating room personnel

Kargar-Shouroki, F., Halvani, G., & Sharmandehmola, F. A. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-022-22873-5 · Cited by 5

Study of Immune Response and Malondialdehyde Levels in Irradiated Rats Supplemented with Curcuma xanthorriza Roxb Extract

Surniyantoro, H. N. E., Kisnanto, T., Tetriana, D., Yusuf, D., Kurnia, I., & Lusiyanti, Y. (2023) · Asian Pacific Journal of Cancer Prevention · doi:10.31557/apjcp.2023.24.5.1717 · Cited by 5

The effect of ionizing radiation on the fetal bone development in pregnant rats: Role of melatonin

Tokpınar, A., Nisari, M., Yılmaz, S., Arzu Hanım, Y. A. Y., Yıldız, O. G., Balcıoğlu, E., Suna, P. A., Bilgici, P., Uçar, S., Ateş, Ş., et al. (2023) · Microscopy Research and Technique · doi:10.1002/jemt.24414 · Cited by 5

The prophylactic roles of dietary antioxidants for medical radiology workers: A mini-review

Khattab, M., Sayed, Z. S., Altaf, R. A., Yasen, N. S., Aiashy, A. A., Alfeqy, H., Khedr, G. H., Atef, S., Ezzat, D., & Nafady, M. H. (2022) · Natural Resources for Human Health · doi:10.53365/nrfhh/146248 · Cited by 5

Oxidative stress and pancreatic cancer: a dual role in tumorigenesis and drug toxicity

Limbu, K. R., Chhetri, R. B., Oh, Y. S., Oak, M., Beak, D. J., & Park, E. (2025) · Toxicological Research · doi:10.1007/s43188-025-00301-3 · Cited by 6

Effects of low-dose ionizing radiation on the molecular pathways linking neurogenesis and autism spectrum disorders in zebrafish embryos

Kollayan, B. Y., Cansız, D., Beler, M., Ünal, İ., Emekli‐Alturfan, E., & Yalçınkaya, ̧. E. (2024) · Drug and Chemical Toxicology · doi:10.1080/01480545.2024.2318444 · Cited by 4

The Mitigating Effect of Melatonin Against Radiation-Induced Inflammation and Disturbance of Reproductive Hormones in Female Albino Rats

Shedid, S. M., Abdel-Aziz, N., Algeda, F. R., & Saada, H. N. (2025) · Dose-Response · doi:10.1177/15593258251323796 · Cited by 4

An Update on Role of Ionizing Radiation to Enhance Proliferation and Differentiation of Normal Stem Cells via Activation of NRF2 Pathway: Review

Moloudi, K., & Haghdoost, S. (2025) · Antioxidants · doi:10.3390/antiox14080986 · Cited by 4

Assessing radiation-induced enzyme activation in Aedes aegypti: Potential challenges for SIT-based vector management

da Silva, E. B., Florêncio, S. G. L., Amaral, A., & de Melo-Santos, M. A. V. (2024) · Acta Tropica · doi:10.1016/j.actatropica.2024.107518 · Cited by 4

0.5 Gy confers resistance to a subsequent high dose of γ-rays by modulating HO-1/Nrf2 and apoptosis pathways

Ali, Y. F., Hassan, I. M., Abdelhafez, H. M., & Desouky, O. S. (2025) · Scientific Reports · doi:10.1038/s41598-025-91667-9 · Cited by 4

Future Perspectives in Oxidative Stress in Trisomy 13 and 18 Evaluation

Buczyńska, A., Sidorkiewicz, I., Hameed, A., Kretowski, A. J., & Zbucka-Krętowska, M. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11071787 · Cited by 5

Radioprotective effects of gliclazide against irradiation-induced cardiotoxicity and lung injury through inhibiting oxidative stress

Amiri, F. T., Arzani, S., Farzipour, S., & Hosseinimehr, S. J. (2022) · Medical Oncology · doi:10.1007/s12032-022-01803-y · Cited by 4

Fat-Soluble Vitamin Deficiencies and Disruption of the Immune System in Pancreatic Cancer

Aziz, M. H., van der Meulen, J., Mustafa, D. A. M., & van Eijck, C. H. J. (2022) · Pancreas · doi:10.1097/mpa.0000000000002128 · Cited by 5

Radioprotective Effect of Piperine, as a Major Component of Black Pepper, Against Radiation-induced Colon Injury: Biochemical and Histological Studies

Safarbalou, A., Ebrahimi, F., Amiri, F. T., & Hosseinimehr, S. J. (2023) · Current Radiopharmaceuticals · doi:10.2174/1874471016666230725112319 · Cited by 4

Melatonin and its derivatives

Adedokun, K. A., Bhat, A., Imodoye, S. O., Anifowose, S. O., Fayemo, H. T., Adekola, S. A., Adedeji, A., Bello, I. O., Shittu, M. O., Ralph-Uyalor, I.-A., et al. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13814-0.00013-2 · Cited by 3

Zeolitic Imidazolate Framework-8 (ZIF-8) as a Carrier for Kaempferol Delivery to Protect Against Gamma Radiation-Induced Mortality and Damage

Yang, G., Wang, J., Wang, R., Han, L., Gong, C., Chen, J., Chen, M., & Yuan, Y. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17111489 · Cited by 3

Exploring Microbial Antioxidant Metabolism: Mechanisms, Recent Advances, and Biotechnological Applications

Murugan, D., Singh, S. V. V., Lavanya, M., Marieswaran, K. S., Chithamparam, P., & Muthukumaran, A. (2026) · Springer eBooks · doi:10.1007/978-981-95-3758-7_10 · Cited by 4

Effects of dietary 25-hydroxycholecalciferol supplementation on growth performance, blood vitamin D and antioxidant status in nursery pigs

Kwon, C. H., Safaie, E. S., Locke, S., Torres, J. A., Yang, Z., Chen, X., & Jang, Y. D. (2025) · Animal Bioscience · doi:10.5713/ab.25.0029 · Cited by 3

Syringic acid as a pivotal component in reducing oxidative stress parameters in the civilization diseases - a review

Bartel, I., Mandryk, I., & Koszarska, M. (2024) · Animal Science Papers and Reports · doi:10.2478/aspr-2023-0043 · Cited by 4

Metformin ameliorates vanadium pentoxide or gamma irradiation-stimulated hepatotoxicity in male rats via targeting endoplasmic reticulum stress-induced apoptosis

Gerges, M. N., Abdou, F. Y., Gamal, D. M. E., & Habieb, M. E. (2024) · Human & Experimental Toxicology · doi:10.1177/09603271241307859 · Cited by 2

Synthesis and Characterization of Pyrogallol Silver Nanoparticles and Pyrogallol Nanocomposites and Their Effects on Radiation-Induced Toxicity in HEK239 Cells

Abirami, R., Ramamurthy, R., Parvathikandhan, S., Anbarasu, S. V., Swaminathan, H., Velu, S., Nagaraja, S. S., Nagarajan, D., Kondapavuluri, B. K., & Thiruvengadam, M. (2025) · BioNanoScience · doi:10.1007/s12668-025-01919-1 · Cited by 2

Cardiotoxicity prevention in thoracic radiotherapy: The effect of different melatonin doses on the level of oxidation markers -in vivo animal study

Demir, E., Yanar, K., Atukeren, P., Özkan, S., Şentürk, G. E., Ülker, M., Ergen, Ş. A., Karaçam, S. Ç., & Dinçbaş, F. Ö. (2025) · Toxicology Reports · doi:10.1016/j.toxrep.2025.102030 · Cited by 2

Comparative analysis of melatonin’s protective role against flattening filter and flattening filter-free X-ray induced nephropathy: focus on apoptosis and SIRT1 modulation

Şevgin, K., Sapmaz, T., Erdem, E., Topkaraoğlu, S., Baki, K. B., & Aras, S. (2025) · BMC Nephrology · doi:10.1186/s12882-025-04372-0 · Cited by 2

A multi-tiered workflow for constructing a quantitative adverse outcome pathway network for gamma radiation-induced reproductive inhibition in Lemna minor

Xie, L., & Tollefsen, K. E. (2025) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2025.119129 · Cited by 2

Oxidative stress as a key factor in the pathophysiology of neurodegenerative diseases: molecular mechanisms and protection pathways – Review

Karatchobanov, V., Mateev, E., Mateeva, A., Kondeva-Burdina, M., & Georgieva, M. (2025) · Pharmacia · doi:10.3897/pharmacia.72.e167365 · Cited by 3

The impact of vitamin D supplementation on sudden sensorineural hearing loss in vitamin D deficient patients: A double-blind, placebo-controlled trial: A pilot study

Tavakoli, B., & Rabiei, S. (2026) · American Journal of Otolaryngology · doi:10.1016/j.amjoto.2026.104793 · Cited by 2

Melatonin as Protection Against Radiation Injury: A Systematic Review

Zetner, D. B., Andersen, L. J., & Rosenberg, J. (2016) · Drug Research · doi:10.1055/s-0035-1569358 · Cited by 38

Antioxidative Effects of Melatonin in Protection Against Cellular Damage Caused by Ionizing Radiation

Karbownik‐Lewińska, M., & Reiter, R. J. (2000) · Proceedings of The Society for Experimental Biology and Medicine · doi:10.1111/j.1525-1373.2000.22502.x · Cited by 313

Melatonin as an adjuvant in radiotherapy for radioprotection and radiosensitization

Farhood, B., Goradel, N. H., Mortezaee, K., Khanlarkhani, N., Salehi, E., Nashtaei, M. S., Mirtavoos‐Mahyari, H., Motevaseli, E., Shabeeb, D., Musa, A. E., et al. (2018) · Clinical & Translational Oncology · doi:10.1007/s12094-018-1934-0 · Cited by 144

PROSPECTS OF THE USE OF MELATONIN IN RADIATION THERAPY

Mаkovetska, L. I., & Domina, E. A. (2024) · Oncology · doi:10.15407/oncology.2024.01.005 · Cited by 2

Radio-protective effects of melatonin against irradiation-induced oxidative damage in rat peripheral blood

Shirazi, A., Mihandoost, E., Mohseni, M., Ghazi‐Khansari, M., & Mahdavi, S. R. (2011) · Physica Medica · doi:10.1016/j.ejmp.2011.11.007 · Cited by 45