The DOI matches its Crossref record; 118 of the 118 references it cites were found in a registry or an index.
Fabrication and Applications of Microfluidic Devices: A Review
Open accessAbstract
Microfluidics is a relatively newly emerged field based on the combined principles of physics, chemistry, biology, fluid dynamics, microelectronics, and material science. Various materials can be processed into miniaturized chips containing channels and chambers in the microscale range. A diverse repertoire of methods can be chosen to manufacture such platforms of desired size, shape, and geometry. Whether they are used alone or in combination with other devices, microfluidic chips can be employed in nanoparticle preparation, drug encapsulation, delivery, and targeting, cell analysis, diagnosis, and cell culture. This paper presents microfluidic technology in terms of the available platform materials and fabrication techniques, also focusing on the biomedical applications of these remarkable devices.
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Citations
Cites
The origins and the future of microfluidics
Whitesides, G. M. (2006) · Nature · doi:10.1038/nature05058 · Cited by 9,687
Immunological properties of engineered nanomaterials
Dobrovolskaia, M. A., & McNeil, S. E. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.223 · Cited by 1,823
Evaluation of 3D Printing and Its Potential Impact on Biotechnology and the Chemical Sciences
Gross, B. C., Erkal, J. L., Lockwood, S. Y., Chen, C., & Spence, D. M. (2014) · Analytical Chemistry · doi:10.1021/ac403397r · Cited by 1,746
Becker, H. (2002) · Talanta · doi:10.1016/s0039-9140(01)00594-x · Cited by 1,187
Materials for Microfluidic Chip Fabrication
Ren, K., Zhou, J., & Wu, H. (2013) · Accounts of Chemical Research · doi:10.1021/ar300314s · Cited by 974
Minireview: Nanoparticles and the Immune System
Zolnik, B. S., González-Fernández, A., Sadrieh, N., & Dobrovolskaia, M. A. (2010) · Endocrinology · doi:10.1210/en.2009-1082 · Cited by 914
Microfluidic technologies for accelerating the clinical translation of nanoparticles
Valencia, P. M., Farokhzad, O. C., Karnik, R., & Langer, R. (2012) · Nature Nanotechnology · doi:10.1038/nnano.2012.168 · Cited by 698
Wongkaew, N., Simsek, M., Griesche, C., & Baeumner, A. J. (2019) · Chemical Reviews · doi:10.1021/acs.chemrev.8b00172 · Cited by 657
Convery, N., & Gadegaard, N. (2019) · Micro and Nano Engineering · doi:10.1016/j.mne.2019.01.003 · Cited by 602
Micromilling: a method for ultra-rapid prototyping of plastic microfluidic devices
Guckenberger, D. J., de Groot, T. E., Wan, A. M. D., Beebe, D. J., & Young, E. W. K. (2015) · Lab on a Chip · doi:10.1039/c5lc00234f · Cited by 513
Cited by
Sensors-integrated organ-on-a-chip for biomedical applications
Chen, H., Luo, Z., Lin, X., Zhu, Y., & Zhao, Y. (2023) · Nano Research · doi:10.1007/s12274-023-5651-9 · Cited by 47
Cell Migration Assays and Their Application to Wound Healing Assays—A Critical Review
Yang, C., Yin, D., Zhang, H., Badea, I., Yang, S.-M., & Zhang, W. (2024) · Micromachines · doi:10.3390/mi15060720 · Cited by 22
Metadata
- Authors
- Niculescu, A.-G., Chircov, C., Bîrcă, A. C., & Grumezescu, A. M.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2021-02-18
- Volume
- 22
- Issue
- 4
- Pages
- 2011
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W3129470634
- Cited by
- 678
- References
- 118
- FWCI
- 28.14
- Type
- journal article
- Language
- en
- Open access
- gold
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- Niculescu, A.-G., Chircov, C., Bîrcă, A. C., & Grumezescu, A. M. (2021). Fabrication and Applications of Microfluidic Devices: A Review. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms22042011
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
