The DOI matches its Crossref record; 117 of the 117 references it cites were found in a registry or an index.
Biological Detoxification of Mycotoxins: Current Status and Future Advances
Open accessAbstract
Mycotoxins are highly toxic metabolites produced by fungi that pose a huge threat to human and animal health. Contamination of food and feed with mycotoxins is a worldwide issue, which leads to huge financial losses, annually. Decades of research have developed various approaches to degrade mycotoxins, among which the biological methods have been proved to have great potential and advantages. This review provides an overview on the important advances in the biological removal of mycotoxins over the last decade. Here, we provided further insight into the chemical structures and the toxicity of the main mycotoxins. The innovative strategies including mycotoxin degradation by novel probiotics are summarized in an in-depth discussion on potentialities and limitations. We prospected the promising future for the development of multifunctional approaches using recombinant enzymes and microbial consortia for the simultaneous removal of multiple mycotoxins.
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“In addition, the ability of lactic acid bacteria to remove mycotoxins has been studied by other authors [58,59], including the mycotoxins analyzed in our work Aflatoxin B1 [60] and Ochratoxin [61].”
From Probiotic and Antifungal Attributes of Lactic Acid Bacteria Isolates from Naturally Fermented Brazilian Table Olives (2022) · cites this paper as [59]
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Cites
Mycotoxins: Occurrence, toxicology, and exposure assessment
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Probiotics and their fermented food products are beneficial for health
Parvez, S., Malik, K. A., Ah Kang, S., & Kim, H.-Y. (2006) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2006.02963.x · Cited by 1,435
Probiotics and prebiotics in animal feeding for safe food production
Gaggìa, F., Mattarelli, P., & Biavati, B. (2010) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2010.02.031 · Cited by 1,027
Probiotics in aquaculture: The need, principles and mechanisms of action and screening processes
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Lactic acid bacteria–Potential for control of mould growth and mycotoxins: A review
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Effects of trichothecene mycotoxins on eukaryotic cells: A review
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Trichothecenes: From Simple to Complex Mycotoxins
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Saccharomyces cerevisiae and lactic acid bacteria as potential mycotoxin decontaminating agents
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Fumonisins: Toxicokinetics, mechanism of action and toxicity
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Cell Wall Structure and Function in Lactic Acid Bacteria
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Research works printed but not linked: 1
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Sorted by citations
Godana, E. A., Yang, Q., Zhang, X., Zhao, L., Wang, K., Dhanasekaran, S., Mehari, T. G., & Zhang, H. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c06448 · Cited by 96
A comprehensive review of mycotoxins, their toxicity, and innovative detoxification methods
Shekhar, R., Raghavendra, V. B., & Rachitha, P. (2025) · Toxicology Reports · doi:10.1016/j.toxrep.2025.101952 · Cited by 103
Recent Research on Fusarium Mycotoxins in Maize—A Review
Bryła, M., Pierzgalski, A., Zapaśnik, A., Uwineza, P. A., Ksieniewicz-Woźniak, E., Modrzewska, M., & Waśkiewicz, A. (2022) · Foods · doi:10.3390/foods11213465 · Cited by 84
Mycotoxins in food: Occurrence, health implications, and control strategies-A comprehensive review
Khan, R. (2024) · Toxicon · doi:10.1016/j.toxicon.2024.108038 · Cited by 83
Öztekin, S., Dikmetaş, D. N., Devecioğlu, D., Acar, E. G., & Karbancıoğlu‐Güler, F. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c00315 · Cited by 79
Metadata
- Authors
- Liu, L., Xie, M., & Wei, D.
- Affiliations
- Guangdong Academy of Sciences (CN)
- Beijing Normal-Hong Kong Baptist University (CN)
- Guangdong Province Key Laboratory for Green Processing of Natural Products and Product Safety (CN)
- Corresponding author
- Wei, Dong
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2022-01-19
- Volume
- 23
- Issue
- 3
- Pages
- 1064
- ISSN
- 1422-0067 (ISSN-L)
- PMC
- PMC8835436
- OpenAlex
- W4205944514
- Cited by
- 162
- References
- 117
- Citations by year
- 2026: 29 · 2025: 56 · 2024: 34 · 2023: 32 · 2022: 11
- FWCI
- 3.05
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Journal of Molecular Sciences (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- GDAS' Project of Science and Technology Development (2020GDASYL-20200103026)
- National Natural Science Foundation of China (32001812)
- Guangdong Basic and Applied Basic Research Foundation (2019B1515120002)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Mycotoxins in Agriculture and Food
- Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Microbial Natural Products and Biosynthesis
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytase and its Applications
- Keywords
- mycotoxins, detoxification, mycotoxin degradation, probiotics, recombinant enzyme, microbial consortia, food and feed contamination, mycotoxin toxicity
- MeSH terms
- Animals, Food, Food Contamination, Fungi, Inactivation, Metabolic, Mycotoxins
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