The DOI matches its Crossref record; 274 of the 274 references it cites were found in a registry or an index.
Beyond Hemostasis: Platelet Innate Immune Interactions and Thromboinflammation
Open accessAbstract
There is accumulating evidence that platelets play roles beyond their traditional functions in thrombosis and hemostasis, e.g., in inflammatory processes, infection and cancer, and that they interact, stimulate and regulate cells of the innate immune system such as neutrophils, monocytes and macrophages. In this review, we will focus on platelet activation in hemostatic and inflammatory processes, as well as platelet interactions with neutrophils and monocytes/macrophages. We take a closer look at the contributions of major platelet receptors GPIb, αIIbβ3, TLT-1, CLEC-2 and Toll-like receptors (TLRs) as well as secretions from platelet granules on platelet–neutrophil aggregate and neutrophil extracellular trap (NET) formation in atherosclerosis, transfusion-related acute lung injury (TRALI) and COVID-19. Further, we will address platelet–monocyte and macrophage interactions during cancer metastasis, infection, sepsis and platelet clearance.
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Cited by
Understanding COVID-19-associated coagulopathy
Conway, E. M., Mackman, N., Warren, R. Q., Wolberg, A. S., Mosnier, L. O., Campbell, R. A., Gralinski, L. E., Rondina, M. T., van de Veerdonk, F. L., Hoffmeister, K. M., et al. (2022) · Nature Reviews Immunology · doi:10.1038/s41577-022-00762-9 · Cited by 359
Viral sepsis: diagnosis, clinical features, pathogenesis, and clinical considerations
Xu, J.-Q., Zhang, W.-Y., Fu, J.-J., Fang, X.-Z., Gao, C.-G., Li, C., Yao, L., Li, Q.-L., Yang, X.-B., Ren, L.-H., et al. (2024) · Military Medical Research · doi:10.1186/s40779-024-00581-0 · Cited by 37
Metadata
- Authors
- Mandel, J., Casari, M., Stepanyan, M., Martyanov, A., & Deppermann, C.
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2022-03-31
- Volume
- 23
- Issue
- 7
- Pages
- 3868
- ISSN
- 1422-0067 (ISSN-L)
- OpenAlex
- W4220815932
- Cited by
- 253
- References
- 274
- FWCI
- 30.75
- Type
- journal article
- Language
- en
- Open access
- gold
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- Mandel, J., Casari, M., Stepanyan, M., Martyanov, A., & Deppermann, C. (2022). Beyond Hemostasis: Platelet Innate Immune Interactions and Thromboinflammation. International Journal of Molecular Sciences. https://doi.org/10.3390/ijms23073868
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.