The DOI matches its Crossref record; 122 of the 122 references it cites were found in a registry or an index.
Airway Mucus and Asthma: The Role of MUC5AC and MUC5B
Open accessAbstract
Asthma is characterized by mucus abnormalities. Airway epithelial hyperplasia and metaplasia result in changes in stored and secreted mucin and the production of a pathologic mucus gel. Mucus transport is impaired, culminating in mucus plugging and airway obstruction—a major cause of morbidity in asthma. The polymeric mucins MUC5AC and MUC5B are integral components of airway mucus. MUC5AC and MUC5B gene expression is altered in asthma, and recent work sheds light on their contribution to asthma pathogenesis. Herein, we review our current understanding of the role of MUC5AC and MUC5B in mucus dysfunction in asthma.
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Cites
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T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma
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Airway Mucus Function and Dysfunction
Fahy, J. V., & Dickey, B. F. (2010) · New England Journal of Medicine · doi:10.1056/nejmra0910061 · Cited by 1,722
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Lebrikizumab Treatment in Adults with Asthma
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Dupilumab in Persistent Asthma with Elevated Eosinophil Levels
Wenzel, S., Ford, L., Pearlman, D., Spector, S., Sher, L., Skobieranda, F., Wang, L., Kirkesseli, S., Rocklin, R., Bock, B., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1304048 · Cited by 1,320
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A Common MUC5B Promoter Polymorphism and Pulmonary Fibrosis
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Respiratory Tract Mucin Genes and Mucin Glycoproteins in Health and Disease
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THE PATHOLOGY OF ASTHMA, WITH SPECIAL REFERENCE TO CHANGES IN THE BRONCHIAL MUCOSA
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Cited by
Airway Epithelial Differentiation and Mucociliary Clearance
Whitsett, J. A. (2018) · Annals of the American Thoracic Society · doi:10.1513/annalsats.201802-128aw · Cited by 328
Morphologically intact airways in lung fibrosis have an abnormal proteome
Herrera, J. A., Dingle, L. A., Monetero, M. A., Venkateswaran, R. V., Blaikley, J. F., Granato, F., Pearson, S., Lawless, C., & Thornton, D. J. (2023) · Respiratory Research · doi:10.1186/s12931-023-02400-x · Cited by 12
Metadata
- Authors
- Bonser, L., & Erle, D.
- Venue
- Journal of Clinical Medicine
- Publisher
- MDPI AG
- Published
- 2017-11-29
- Volume
- 6
- Issue
- 12
- Pages
- 112
- ISSN
- 2077-0383 (ISSN-L)
- OpenAlex
- W2765851819
- Cited by
- 359
- References
- 122
- FWCI
- 14.59
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
