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Cited by 231

The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.

Fungal Biofilms and Polymicrobial Diseases

Open access
Costa-Orlandi, Caroline, Sardi, Janaina, Pitangui, Nayla, De Oliveira, Haroldo, Scorzoni, Liliana, Galeane, Mariana, Medina-Alarcón, Kaila, Melo, Wanessa, Marcelino, Mônica, Braz, Jaqueline, Fusco-Almeida, Ana, Mendes-Giannini, Maria·2017·Journal of Fungi
DOI 10.3390/jof3020022
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Abstract

Biofilm formation is an important virulence factor for pathogenic fungi. Both yeasts and filamentous fungi can adhere to biotic and abiotic surfaces, developing into highly organized communities that are resistant to antimicrobials and environmental conditions. In recent years, new genera of fungi have been correlated with biofilm formation. However, Candida biofilms remain the most widely studied from the morphological and molecular perspectives. Biofilms formed by yeast and filamentous fungi present differences, and studies of polymicrobial communities have become increasingly important. A key feature of resistance is the extracellular matrix, which covers and protects biofilm cells from the surrounding environment. Furthermore, to achieve cell–cell communication, microorganisms secrete quorum-sensing molecules that control their biological activities and behaviors and play a role in fungal resistance and pathogenicity. Several in vitro techniques have been developed to study fungal biofilms, from colorimetric methods to omics approaches that aim to identify new therapeutic strategies by developing new compounds to combat these microbial communities as well as new diagnostic tools to identify these complex formations in vivo. In this review, recent advances related to pathogenic fungal biofilms are addressed.

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Metadata

Authors
Costa-Orlandi, C., Sardi, J., Pitangui, N., De Oliveira, H., Scorzoni, L., Galeane, M., Medina-Alarcón, K., Melo, W., Marcelino, M., Braz, J., Fusco-Almeida, A., & Mendes-Giannini, M.
Venue
Journal of Fungi
Publisher
MDPI AG
Published
2017-05-10
Volume
3
Issue
2
Pages
22
ISSN
2309-608X (ISSN-L)
DOI
10.3390/jof3020022
OpenAlex
W2614095332
Cited by
231
References
42
FWCI
10.61
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Fungal Biofilms and Polymicrobial Diseases. https://app.cochat.ai/papers/10.3390/jof3020022
The paper
Costa-Orlandi, C., Sardi, J., Pitangui, N., De Oliveira, H., Scorzoni, L., Galeane, M., Medina-Alarcón, K., Melo, W., Marcelino, M., Braz, J., Fusco-Almeida, A., & Mendes-Giannini, M. (2017). Fungal Biofilms and Polymicrobial Diseases. Journal of Fungi. https://doi.org/10.3390/jof3020022

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.