The DOI matches its Crossref record; 151 of the 152 references it cites were found in a registry or an index.
Terpenoids and Their Biosynthesis in Cyanobacteria
Open accessAbstract
Terpenoids, or isoprenoids, are a family of compounds with great structural diversity which are essential for all living organisms. In cyanobacteria, they are synthesized from the methylerythritol-phosphate (MEP) pathway, using glyceraldehyde 3-phosphate and pyruvate produced by photosynthesis as substrates. The products of the MEP pathway are the isomeric five-carbon compounds isopentenyl diphosphate and dimethylallyl diphosphate, which in turn form the basic building blocks for formation of all terpenoids. Many terpenoid compounds have useful properties and are of interest in the fields of pharmaceuticals and nutrition, and even potentially as future biofuels. The MEP pathway, its function and regulation, and the subsequent formation of terpenoids have not been fully elucidated in cyanobacteria, despite its relevance for biotechnological applications. In this review, we summarize the present knowledge about cyanobacterial terpenoid biosynthesis, both regarding the native metabolism and regarding metabolic engineering of cyanobacteria for heterologous production of non-native terpenoids.
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“terpenoids from the MEP pathway, which uses pyruvate and glyceraldehyde-3-phosphate as precursors [29]”
From Cyanobacteria as a Photosynthetic Chassis for Metabolic Pathway Engineering with Heterologous Gene Expression (2026) · cites this paper as [29]
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Metadata
- Authors
- Pattanaik, B., & Lindberg, P.
- Affiliations
- Uppsala University (SE)
- Corresponding author
- Lindberg, Pia
- ORCID
- Lindberg, Pia
- Venue
- Life
- Publisher
- MDPI AG
- Published
- 2015-01-21
- Volume
- 5
- Issue
- 1
- Pages
- 269-293
- ISSN
- 2075-1729 (ISSN-L)
- PMC
- PMC4390852
- OpenAlex
- W2058582378
- Cited by
- 173
- References
- 152
- Citations by year
- 2026: 10 · 2025: 9 · 2024: 25 · 2023: 19 · 2022: 15 · 2021: 19 · 2020: 29 · 2019: 13 · 2018: 12 · 2017: 10 · 2016: 8 · 2015: 4
- FWCI
- 1.10
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Life (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- Carl Tryggers Stiftelse för Vetenskaplig Forskning
- Knut och Alice Wallenbergs Stiftelse
- Energimyndigheten
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
- Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Microbial Natural Products and Biosynthesis
- Keywords
- terpenoids, cyanobacteria, methylerythritol phosphate pathway, isopentenyl pyrophosphate, dimethylallyl diphosphate, terpenoid biosynthesis, metabolic engineering, heterologous production, biofuels
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