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Cited by 29Bone Tissue Engineering MaterialsNanocomposite Films for Food PackagingSurface Treatment and Coatings

Impact of Gamma Irradiation on the Properties of Magnesium-Doped Hydroxyapatite in Chitosan Matrix

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Predoi, Daniela, Ciobanu, Carmen Steluta, Iconaru, Simona Liliana, Predoi, Silviu Adrian, Chifiriuc, Mariana Carmen, Raaen, Steinar, Badea, Monica Luminita, Rokosz, Krzysztof·2022·Materials
DOI 10.3390/ma15155372PMC PMC9369862
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Abstract

This is the first report regarding the effect of gamma irradiation on chitosan-coated magnesium-doped hydroxyapatite (xMg = 0.1; 10 MgHApCh) layers prepared by the spin-coating process. The stability of the resulting 10 MgHApCh gel suspension used to obtain the layers has been shown by ultrasound measurements. The presence of magnesium and the effect of the irradiation process on the studied samples were shown by X-ray photoelectron spectroscopy (XPS). The XPS results obtained for irradiated 10 MgHApCh layers suggested that the magnesium and calcium contained in the surface layer are from tricalcium phosphate (TCP; Ca3(PO4)2) and hydroxyapatite (HAp). The XPS analysis has also highlighted that the amount of TCP in the surface layer increased with the irradiation dose. The energy-dispersive X-ray spectroscopy (EDX) evaluation showed that the calcium decreases with the increase in the irradiation dose. In addition, a decrease in crystallinity and crystallite size was highlighted after irradiation. By atomic force microscopy (AFM) we have obtained images suggesting a good homogeneity of the surface of the non-irradiated and irradiated layers. The AFM results were also sustained by the scanning electron microscopy (SEM) images obtained for the studied samples. The effect of gamma-ray doses on the Fourier transform infrared spectroscopy (ATR-FTIR) spectra of 10 MgHApCh composite layers was also evaluated. The in vitro antifungal assays proved that 10 MgHApCh composite layers presented a strong antifungal effect, correlated with the irradiation dose and incubation time. The study of the stability of the 10 MgHApCh gel allowed us to achieve uniform and homogeneous layers that could be used in different biomedical applications.

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  • The position of the peak corresponding to the P−O bond remains unchanged, and the P 2p peaks appear at 130.6 and 129.8 eV.

    “The position of the peak (Figure 2) corresponding to the P−O bond remains unchanged,34,35 and the P 2p peaks appear at 130.6 and 129.8 eV.”

    From Silver Nanowire Aerogel Support Promotes Stable Hydrogen Evolution Reaction at High Current Density (2024) · cites this paper as [34]

    The citation is attached to the assertion that the P–O peak position remains unchanged. In Results (Figure 13), the paper instead says that the ATR-FTIR peaks’ positions are slightly displaced as irradiation dose increases. The P 2p values appear after the citation and are not treated as attributed to this source. (LLM, conf=0.86)

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Authors
Predoi, D., Ciobanu, C. S., Iconaru, S. L., Predoi, S. A., Chifiriuc, M. C., Raaen, S., Badea, M. L., & Rokosz, K.
Affiliations
  • National Institute of Materials Physics (RO)
  • National Institute of Materials Physics, Atomistilor Street, No. 405A, 77125 Magurele, Romania
  • École Normale Supérieure Paris-Saclay (FR)
  • University of Bucharest (RO)
  • Norwegian University of Science and Technology (NO)
  • Koszalin University of Technology (PL)
Corresponding author
  • Predoi, Daniela
  • Rokosz, Krzysztof
ORCID
Venue
Materials
Publisher
MDPI AG
Published
2022-08-04
Volume
15
Issue
15
Pages
5372
ISSN
1996-1944 (ISSN-L)
DOI
10.3390/ma15155372
PMC
PMC9369862
OpenAlex
W4289942375
Cited by
29
References
2
Citations by year
2026: 3 · 2025: 5 · 2024: 8 · 2023: 11 · 2022: 2
FWCI
1.89
Type
journal article
Language
en
Open access
Licence
Locations
  • Materials (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • NORA - Norwegian Open Research Archives (submittedVersion, cc-by)
Funders
  • Romanian Ministry of Research (331PED/2020, 41PFE/30.12.2021)
  • PN-III-P2-2.1-PED-2019-1375 (331PED/2020, 41PFE/30.12.2021)
  • 35PFE/2021 (331PED/2020, 41PFE/30.12.2021)
  • PNIII-1.2PDI-PFE-C1-2021 (331PED/2020, 41PFE/30.12.2021)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
  • Physical Sciences › Materials Science › Biomaterials › Nanocomposite Films for Food Packaging
  • Physical Sciences › Engineering › Mechanical Engineering › Surface Treatment and Coatings
Keywords
gamma irradiation, magnesium-doped hydroxyapatite, chitosan matrix, tricalcium phosphate, antifungal activity, composite coatings, crystallinity, radiation dose, dental biomaterials

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