Candida Biofilms: an Update

Ramage, Gordon; Saville, Stephen P.; Thomas, Derek P.; López-Ribot, José L.

doi:10.1128/ec.4.4.633-638.2005

Cited by 678Antifungal resistance and susceptibilityBacterial biofilms and quorum sensingFungal and yeast genetics research

Candida Biofilms: an Update

Open access

Ramage, Gordon, Saville, Stephen P., Thomas, Derek P., López-Ribot, José L.·2005·Eukaryotic Cell

DOI 10.1128/ec.4.4.633-638.2005PMC PMC1087806

Open this paper in CoChat — free account

Abstract

Our classical perception of microorganisms as unicellular life forms is almost entirely based on the pure-culture mode of growth; since microbial suspensions can be diluted to a single cell and studied in liquid culture, this mode of growth has traditionally predominated in the study of microbial physiology and pathogenesis in the research laboratory. However, many microbes in their natural habitats are found in biofilm ecosystems attached to surfaces and not as free-floating (planktonic) organisms (20, 21, 27). Thus, biofilms are defined as structured microbial communities that are attached to a surface and encased in a matrix of exopolymeric material. This is of particular significance since it is now estimated that a significant proportion of all human microbial infections involve biofilm formation (20, 22, 25, 26, 29, 48).

Integrity signals

Registry

Crossref · 10.1128/ec.4.4.633-638.2005

Cites

89 of 89 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Biofilm formation on medical devices can negatively impact the host by causing device failure and serving as a reservoir for future infections.
“Biofilm formation on medical devices can negatively impact the host by causing the failure of the device and by serving as a reservoir or source for future continuing infections [25].”
From In vitro antifungal activity of hydroxychavicol isolated from Piper betle L (2010) · cites this paper as [25]
The formation of Candida biofilms raises important clinical issues because of a significant further increase in antifungal drug resistance as well as evasion of host immune defenses.
“The formation of Candida biofilms raises important clinical issues because of a significant further increase in antifungal drug resistance as well as evasion of host immune defenses.”
From Candida glabrata susceptibility to antifungals and phagocytosis is modulated by acetate (2015) · cites this paper as Ramage et al., 2005
Candida albicans forms biofilms on catheters and medical devices, which may be impossible to cure unless the device is removed.
“Candida albicans also forms biofilms on catheters and medical devices, which may be impossible to cure unless the device is removed [1,2].”
From In vitro analysis of flufenamic acid activity against Candida albicans biofilms (2014) · cites this paper as [1]
Candida albicans forms biofilms, a characteristic that enhances resistance to antifungal agents and permits colonisation of mucosal surfaces with potential for subsequent dissemination.
“The opportunistic fungal pathogen Candida albicans has the ability to form biofilms, a characteristic that enhances resistance to antifungal agents and permits colonisation of mucosal surfaces with the potential for subsequent dissemination [1].”
From In vitro analysis of flufenamic acid activity against Candida albicans biofilms (2014) · cites this paper as [1]

National Committee for Clinical Laboratory Standards
Bruck, E. (1980) · PEDIATRICS · doi:10.1542/peds.65.1.187 · Cited by 14,736 · see citing works
Bacterial Biofilms: A Common Cause of Persistent Infections
Costerton, J. W., Stewart, P. S., & Greenberg, E. P. (1999) · Science · doi:10.1126/science.284.5418.1318 · Cited by 12,167 · see citing works
Quorum Sensing in Bacteria
Miller, M. B., & Bassler, B. L. (2001) · Annual Review of Microbiology · doi:10.1146/annurev.micro.55.1.165 · Cited by 5,127 · see citing works
Biofilms: Microbial Life on Surfaces
Donlan, R. M. (2002) · Emerging infectious diseases · doi:10.3201/eid0809.020063 · Cited by 4,894 · see citing works
MICROBIAL BIOFILMS
Costerton, J. W., Lewandowski, Z., Caldwell, D. E., Korber, D. R., & Lappin-Scott, H. M. (1995) · Annual Review of Microbiology · doi:10.1146/annurev.mi.49.100195.003431 · Cited by 4,718 · see citing works
Biofilm formation as microbial development
O'Toole, G., Kaplan, H. B., & Kolter, R. (2000) · Annual Review of Microbiology · doi:10.1146/annurev.micro.54.1.49 · Cited by 3,571 · see citing works
Bacterial Biofilms in Nature and Disease
Costerton, J. W., Cheng, K. J., Geesey, G. G., Ladd, T. I., Nickel, J. C., Dasgupta, M., & Marrie, T. J. (1987) · Annual Review of Microbiology · doi:10.1146/annurev.mi.41.100187.002251 · Cited by 3,145 · see citing works
Riddle of Biofilm Resistance
Lewis, K. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.4.999-1007.2001 · Cited by 1,988 · see citing works
Biofilm Formation by the Fungal Pathogen Candida albicans : Development, Architecture, and Drug Resistance
Chandra, J., Kuhn, D. M., Mukherjee, P. K., Hoyer, L. L., McCormick, T., & Ghannoum, M. A. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.18.5385-5394.2001 · Cited by 1,578 · see citing works
Biofilms and Device-Associated Infections
Donlan, R. M. (2001) · Emerging infectious diseases · doi:10.3201/eid0702.010226 · Cited by 1,425 · see citing works
Clinical, Cellular, and Molecular Factors That Contribute to Antifungal Drug Resistance
White, T. C., Marr, K. A., & Bowden, R. A. (1998) · Clinical Microbiology Reviews · doi:10.1128/cmr.11.2.382 · Cited by 1,353 · see citing works
Biofilm Formation: A Clinically Relevant Microbiological Process
Donlan, R. M. (2001) · Clinical Infectious Diseases · doi:10.1086/322972 · Cited by 1,343 · see citing works
Candida biofilms and their role in infection
Douglas, L. J. (2003) · Trends in Microbiology · doi:10.1016/s0966-842x(02)00002-1 · Cited by 1,150 · see citing works
Secular Trends in the Epidemiology of Nosocomial Fungal Infections in the United States, 1980-1990
Beck‐Sagué, C. M., Jarvis, W. R., & System, N. N. I. S. (1993) · The Journal of Infectious Diseases · doi:10.1093/infdis/167.5.1247 · Cited by 1,140 · see citing works
Candida Infections of Medical Devices
Kojic, E. M., & Darouiche, R. O. (2004) · Clinical Microbiology Reviews · doi:10.1128/cmr.17.2.255-267.2004 · Cited by 1,055 · see citing works
Quorum Sensing in the Dimorphic Fungus Candida albicans Is Mediated by Farnesol
Hornby, J. M., Jensen, E. C., Lisec, A. D., Tasto, J. J., Jahnke, B., Shoemaker, R., Dussault, P., & Nickerson, K. W. (2001) · Applied and Environmental Microbiology · doi:10.1128/aem.67.7.2982-2992.2001 · Cited by 983 · see citing works
Candida and candidiasis.
Calderone, R. (2012) · ASM Press eBooks · Cited by 912 · see citing works
Development of Interpretive Breakpoints for Antifungal Susceptibility Testing: Conceptual Framework and Analysis of In Vitro-In Vivo Correlation Data for Fluconazole, Itraconazole, and Candida Infections
Rex, J. H., Pfaller, M. A., Galgiani, J. N., Bartlett, M. S., Espinel-Ingroff, A., Ghannoum, M. A., Lancaster, M., Odds, F. C., Rinaldi, M. G., Walsh, T. J., et al. (1997) · Clinical Infectious Diseases · doi:10.1093/clinids/24.2.235 · Cited by 855 · see citing works
Hospital-Acquired Candidemia: The Attributable Mortality and Excess Length of Stay
Wey, S. B. (1988) · Archives of Internal Medicine · doi:10.1001/archinte.1988.00380120094019 · Cited by 831 · see citing works
Antifungal Susceptibility of Candida Biofilms: Unique Efficacy of Amphotericin B Lipid Formulations and Echinocandins
Kuhn, D. M., George, T., Chandra, J., Mukherjee, P. K., & Ghannoum, M. A. (2002) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.46.6.1773-1780.2002 · Cited by 765 · see citing works
Standardized Method for In Vitro Antifungal Susceptibility Testing of Candida albicans Biofilms
Ramage, G., Vande Walle, K., Wickes, B. L., & López-Ribot, J. L. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.9.2475-2479.2001 · Cited by 753 · see citing works
Self-citation
Cell Wall and Secreted Proteins ofCandida albicans: Identification, Function, and Expression
Chaffin, W. L., López-Ribot, J. L., Casanova, M., Gozalbo, D., & Martínez, J. P. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.1.130-180.1998 · Cited by 726 · see citing works
Self-citation
Inhibition of Candida albicans Biofilm Formation by Farnesol, a Quorum-Sensing Molecule
Ramage, G., Saville, S. P., Wickes, B. L., & Lopez-Ribot, J. L. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.11.5459-5463.2002 · Cited by 702 · see citing works
Self-citation
Biofilm formation by Candida species on the surface of catheter materials in vitro
Hawser, S. P., & Douglas, L. J. (1994) · Infection and Immunity · doi:10.1128/iai.62.3.915-921.1994 · Cited by 599 · see citing works
Antifungal Resistance of Candidal Biofilms Formed on Denture Acrylic in vitro
Chandra, J., Mukherjee, P. K., Leidich, S. D., Faddoul, F., Hoyer, L. L., Douglas, L., & Ghannoum, M. A. (2001) · Journal of Dental Research · doi:10.1177/00220345010800031101 · Cited by 588 · see citing works
Pseudomonas - Candida Interactions: An Ecological Role for Virulence Factors
Hogan, D. A., & Kolter, R. (2002) · Science · doi:10.1126/science.1070784 · Cited by 580 · see citing works
A Pseudomonas aeruginosa quorum‐sensing molecule influences Candida albicans morphology
Hogan, D. A., Vik, Å., & Kolter, R. (2004) · Molecular Microbiology · doi:10.1111/j.1365-2958.2004.04349.x · Cited by 575 · see citing works
Mechanism of Fluconazole Resistance in Candida albicans Biofilms: Phase-Specific Role of Efflux Pumps and Membrane Sterols
Mukherjee, P. K., Chandra, J., Kuhn, D. M., & Ghannoum, M. A. (2003) · Infection and Immunity · doi:10.1128/iai.71.8.4333-4340.2003 · Cited by 511 · see citing works
Tyrosol is a quorum-sensing molecule in Candida albicans
Chen, H., Fujita, M., Feng, Q., Clardy, J., & Fink, G. R. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0401416101 · Cited by 500 · see citing works
Denture stomatitis: a role for Candida biofilms
Ramage, G., Tomsett, K., Wickes, B. L., López-Ribot, J. L., & Redding, S. W. (2004) · Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology · doi:10.1016/j.tripleo.2003.04.002 · Cited by 489 · see citing works
Self-citation
Comparison of Biofilms Formed byCandidaalbicansandCandidaparapsilosison Bioprosthetic Surfaces
Kuhn, D. M., Chandra, J., Mukherjee, P. K., & Ghannoum, M. A. (2002) · Infection and Immunity · doi:10.1128/iai.70.2.878-888.2002 · Cited by 485 · see citing works
Fungal morphogenesis and host invasion
Gow, N. A. R., Brown, A. J. P., & Odds, F. C. (2002) · Current Opinion in Microbiology · doi:10.1016/s1369-5274(02)00338-7 · Cited by 482 · see citing works
Investigation of multidrug efflux pumps in relation to fluconazole resistance in Candida albicans biofilms
Ramage, G. (2002) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkf049 · Cited by 468 · see citing works
Self-citation
Resistance of Candida albicans biofilms to antifungal agents in vitro
Hawser, S., & Douglas, L. (1995) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.39.9.2128 · Cited by 407 · see citing works
Matrix polymers of Candida biofilms and their possible role in biofilm resistance to antifungal agents
Baillie, G. S. (2000) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/46.3.397 · Cited by 389 · see citing works
Development and Characterization of an In Vivo Central Venous Catheter Candida albicans Biofilm Model
Andes, D., Nett, J., Oschel, P., Albrecht, R., Marchillo, K., & Pitula, A. (2004) · Infection and Immunity · doi:10.1128/iai.72.10.6023-6031.2004 · Cited by 389 · see citing works
The direct cost and incidence of systemic fungal infections
Wilson, L. S., Reyes, C. M., Stolpman, M., Speckman, J., Allen, K., & Beney, J. (2002) · Value in Health · doi:10.1046/j.1524-4733.2002.51108.x · Cited by 374 · see citing works
Mixed species biofilms of Candida albicans and Staphylococcus epidermidis
ADAM, B., Baillie, G. S., & Douglas, L. (2002) · Journal of Medical Microbiology · doi:10.1099/0022-1317-51-4-344 · Cited by 374 · see citing works
Characteristics of biofilm formation by Candida albicans.
Ramage, G., VandeWalle, K., Wickes, B. L., & Lopez-Ribot, J. L. (2001) · PubMed · Cited by 370 · see citing works
Self-citation
Fungal Transporters Involved in Efflux of Natural Toxic Compounds and Fungicides
Sorbo, G. D., Schoonbeek, H., & Waard, M. A. D. (2000) · Fungal Genetics and Biology · doi:10.1006/fgbi.2000.1206 · Cited by 360 · see citing works
Oral colonization by Candida albicans.
Cannon, R. D., & Chaffin, W. (1999) · Critical Reviews in Oral Biology and Medicine · doi:10.1177/10454411990100030701 · Cited by 357 · see citing works
Candida albicans Biofilms: a Developmental State Associated With Specific and Stable Gene Expression Patterns
García-Sánchez, S., Aubert, S., Iraqui, I., Janbon, G., Ghigo, J.-M., & d'Enfert, C. (2004) · Eukaryotic Cell · doi:10.1128/ec.3.2.536-545.2004 · Cited by 353 · see citing works
The filamentation pathway controlled by the Efg1 regulator protein is required for normal biofilm formation and development inCandida albicans
Ramage, G., VandeWalle, K., LÃ³pez-Ribot, J. L., & Wickes, B. L. (2002) · FEMS Microbiology Letters · doi:10.1016/s0378-1097(02)00853-4 · Cited by 334 · see citing works
Self-citation
Quantitative variation of biofilms among strains in natural populations of Candida albicans
Li, X., Yan, Z., & Xu, J. (2003) · Microbiology · doi:10.1099/mic.0.25932-0 · Cited by 304 · see citing works
Role of dimorphism in the development of Candida albicans biofilms
BAILLIE, G. S., & DOUGLAS, L. J. (1999) · Journal of Medical Microbiology · doi:10.1099/00222615-48-7-671 · Cited by 304 · see citing works
Regulatory networks controlling Candida albicans morphogenesis
Brown, A. J. P., & Gow, N. A. R. (1999) · Trends in Microbiology · doi:10.1016/s0966-842x(99)01556-5 · Cited by 301 · see citing works
Fungal Biofilms and Drug Resistance
Jabra-Rizk, M. A., Falkler, W. A., & Meiller, T. F. (2004) · Emerging Infectious Diseases · doi:10.3201/eid1001.030119 · Cited by 292 · see citing works
In Vitro Activity of Caspofungin against Candida albicans Biofilms
Bachmann, S. P., VandeWalle, K., Ramage, G., Patterson, T. F., Wickes, B. L., Graybill, J. R., & López-Ribot, J. L. (2002) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.46.11.3591-3596.2002 · Cited by 288 · see citing works
Self-citation
Is there a role for quorum sensing signals in bacterial biofilms?
Kjelleberg, S. J., & Molin, S. (2002) · Current Opinion in Microbiology · doi:10.1016/s1369-5274(02)00325-9 · Cited by 263 · see citing works
Intravascular Catheter-Associated Infections
Crump, J. A., & Collignon, P. (2000) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s100960050001 · Cited by 252 · see citing works
Candidemia at a Tertiary-Care Hospital: Epidemiology, Treatment, Clinical Outcome and Risk Factors for Death
Viudes, A., Pemán, J., Cantón, R., Úbeda, P., Lopez-Ribot, J. L., & Gobernado, M. (2002) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-002-0822-1 · Cited by 248 · see citing works
Self-citation
In Vitro Pharmacodynamic Properties of Three Antifungal Agents against PreformedCandida albicansBiofilms Determined by Time-Kill Studies
Ramage, G., VandeWalle, K., Bachmann, S. P., Wickes, B. L., & Lopez-Ribot, J. L. (2002) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.46.11.3634-3636.2002 · Cited by 238 · see citing works
Self-citation
Penetration of Candida Biofilms by Antifungal Agents
Al-Fattani, M. A., & Douglas, L. J. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.9.3291-3297.2004 · Cited by 235 · see citing works
Effect of Growth Rate on Resistance of Candida albicans Biofilms to Antifungal Agents
Baillie, G. S., & Douglas, L. J. (1998) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.42.8.1900 · Cited by 234 · see citing works
cDNA Microarray Analysis of Differential Gene Expression in Candida albicans Biofilm Exposed to Farnesol
Cao, Y., Cao, Y., Xu, Z. Q., Ying, K., Li, Y., Xie, Y., Zhu, Z., Chen, W., & Jiang, Y. (2005) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.49.2.584-589.2005 · Cited by 220 · see citing works
The biofilm glycocalyx as a resistance factor
Hoyle, B. D., Jaß, J., & Costerton, J. W. (1990) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/26.1.1 · Cited by 219 · see citing works
Candida biofilms
Kumamoto, C. A. (2002) · Current Opinion in Microbiology · doi:10.1016/s1369-5274(02)00371-5 · Cited by 217 · see citing works
EAP1, a Candida albicans Gene Involved in Binding Human Epithelial Cells
Li, F., & Palecek, S. (2003) · Eukaryotic Cell · doi:10.1128/ec.2.6.1266-1273.2003 · Cited by 200 · see citing works
Medical importance of biofilms in Candida infections.
Douglas, L. J. (2002) · PubMed · Cited by 195 · see citing works
Production of extracellular matrix by Candida albicans biofilms
Hawser, S., Baillie, G. S., & Douglas, L. (1998) · Journal of Medical Microbiology · doi:10.1099/00222615-47-3-253 · Cited by 184 · see citing works
RT-PCR detection of Candida albicans ALS gene expression in the reconstituted human epithelium (RHE) model of oral candidiasis and in model biofilms.
Green, C. B., Cheng, G., Chandra, J., Mukherjee, P., Ghannoum, M., & Hoyer, L. (2004) · Microbiology · doi:10.1099/mic.0.26699-0 · Cited by 183 · see citing works
Rabbit Model of Candida albicans Biofilm Infection: Liposomal Amphotericin B Antifungal Lock Therapy
Schinabeck, M. K., Long, L. A., Hossain, M. A., Chandra, J., Mukherjee, P. K., Mohamed, S., & Ghannoum, M. A. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.5.1727-1732.2004 · Cited by 181 · see citing works
The Candida albicans CaACE2 gene affects morphogenesis, adherence and virulence
Kelly, M. T., MacCallum, D. M., Clancy, S. D., Odds, F. C., Brown, A. J. P., & Butler, G. (2004) · Molecular Microbiology · doi:10.1111/j.1365-2958.2004.04185.x · Cited by 175 · see citing works
Candida biofilms: antifungal resistance and emerging therapeutic options.
Kuhn, D. M., & Ghannoum, M. A. (2004) · PubMed · Cited by 166 · see citing works
In Vitro and Ex Vivo Activities of Minocycline and EDTA against Microorganisms Embedded in Biofilm on Catheter Surfaces
RAAD, I. I., Chatzinikolaou, I., Chaiban, G., Hanna, H. A., Hachem, R. Y., Dvorak, T. L., Cook, G. S., & Costerton, W. J. (2003) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.47.11.3580-3585.2003 · Cited by 166 · see citing works
Biofilms in device-related infections
Khardori, N. M., & Yassien, M. A. M. (1995) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/bf01569817 · Cited by 161 · see citing works
[48] Candida biofilms and their susceptibility to antifungal agents
Baillie, G. S., & Douglas, L. (1999) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(99)10050-8 · Cited by 160 · see citing works
Biofilm Formation by Candida dubliniensis
Ramage, G., Walle, K. V., Wickes, B. L., & Lopez-Ribot, J. L. (2001) · Journal of Clinical Microbiology · doi:10.1128/jcm.39.9.3234-3240.2001 · Cited by 160 · see citing works
Self-citation
The Two-Component Signal Transduction Protein Chk1p Regulates Quorum Sensing in Candida albicans
Kruppa, M., Krom, B. P., Chauhan, N., Bambach, A. V., Cihlar, R. L., & Calderone, R. (2004) · Eukaryotic Cell · doi:10.1128/ec.3.4.1062-1065.2004 · Cited by 144 · see citing works
Comparison of a 2,3-Bis(2-Methoxy-4-Nitro-5-Sulfophenyl)-5-[(Phenylamino)Carbonyl]-2 H -Tetrazolium Hydroxide (XTT) Colorimetric Method with the Standardized National Committee for Clinical Laboratory Standards Method of Testing Clinical Yeast Isolates for Susceptibility to Antifungal Agents
Hawser, S., Norris, H. A., Jessup, C. J., & Ghannoum, M. A. (1998) · Journal of Clinical Microbiology · doi:10.1128/jcm.36.5.1450-1452.1998 · Cited by 140 · see citing works
Susceptibility of Candida albicans biofilms grown in a constant depth film fermentor to chlorhexidine, fluconazole and miconazole: a longitudinal study
Lamfon, H. A. (2004) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkh071 · Cited by 115 · see citing works
Biofilms of Candida albicans and their associated resistance to antifungal agents.
Ramage, G., Wickes, B. L., & Lopez-Ribot, J. L. (2001) · PubMed · Cited by 114 · see citing works
Self-citation
Adherence of Candida albicans to Silicone Induces Immediate Enhanced Tolerance to Fluconazole
Mateus, C., Crow, S. A., & Ahearn, D. G. (2004) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.48.9.3358-3366.2004 · Cited by 113 · see citing works
Antifungal Activity of Amphotericin B, Fluconazole, and Voriconazole in an In Vitro Model of Candida Catheter-Related Bloodstream Infection
Lewis, R. E., Kontoyiannis, D. P., Darouiche, R. O., RAAD, I. I., & Prince, R. A. (2002) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.46.11.3499-3505.2002 · Cited by 96 · see citing works
Innovative endpoint determination system for antifungal susceptibility testing of yeasts
Tellier, R., Krajden, M., Grigoriew, G. A., et al. (1992) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.36.8.1619 · Cited by 94 · see citing works
Iron-Limited Biofilms of Candida albicans and Their Susceptibility to Amphotericin B
Baillie, G. S., & Douglas, L. (1998) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.42.8.2146 · Cited by 94 · see citing works
Antifungal Combinations against Candida albicans Biofilms In Vitro
Bachmann, S. P., Ramage, G., VandeWalle, K., Patterson, T. F., Wickes, B. L., & López-Ribot, J. L. (2003) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.47.11.3657-3659.2003 · Cited by 89 · see citing works
Self-citation
Formation of Candida albicans biofilms on non‐shedding oral surfaces
Lamfon, H. A., Porter, S. R., McCullough, M. J., & Pratten, J. R. (2003) · European Journal Of Oral Sciences · doi:10.1111/j.0909-8836.2003.00084.x · Cited by 88 · see citing works
Interactions ofCandida albicans with bacteria and salivary molecules in oral biofilms
Holmes, A. R., Cannon, R. D., & Jenkinson, H. F. (1995) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/bf01569827 · Cited by 76 · see citing works
Integration of Raman microscopy, differential interference contrast microscopy, and attenuated total reflection Fourier transform infrared spectroscopy to investigate chlorhexidine spatial and temporal distribution in Candida albicans biofilms
Suci, P. A., Geesey, G. G., & Tyler, B. J. (2001) · Journal of Microbiological Methods · doi:10.1016/s0167-7012(01)00268-8 · Cited by 65 · see citing works
Lack of Catheter Infection by the efg1 / efg1 cph1 / cph1 Double-Null Mutant, a Candida albicans Strain That Is Defective in Filamentous Growth
Lewis, R. E., Lo, H., RAAD, I. I., & Kontoyiannis, D. P. (2002) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.46.4.1153-1155.2002 · Cited by 64 · see citing works
Comparisons of the susceptibilities of planktonic and adherentCandida albicansto antifungal agents: a modified XTT tetrazolium assay using synchronisedC. albicanscells
Hawser, S. (1996) · Medical Mycology · doi:10.1080/02681219680000231 · Cited by 64 · see citing works
The glycocalyx, biofilm, microbes, and resistant infection.
Gristina, A. G., Shibata, Y., Giridhar, G., et al. (1994) · PubMed · Cited by 58 · see citing works
Adhesion of differentCandidaspp. to plastic: XTT formazan determinations
Hawser, S. (1996) · Medical Mycology · doi:10.1080/02681219680000721 · Cited by 54 · see citing works
Adhesion and surface-aggregation of Candida albicans from saliva on acrylic surfaces with adhering bacteria as studied in a parallel plate flow chamber
Millsap, K. W., Bos, R., van der Mei, H. C., et al. (1999) · Antonie van Leeuwenhoek · doi:10.1023/a:1002014306612 · Cited by 42 · see citing works
Deletion of the NOT4 gene impairs hyphal development and pathogenicity in Candida albicans
Krueger, K. E., Ghosh, A. K., Krom, B. P., & Cihlar, R. L. (2003) · Microbiology · doi:10.1099/mic.0.26792-0 · Cited by 38 · see citing works
Adhesive interactions between voice prosthetic yeast and bacteria on silicone rubber in the absence and presence of saliva
Millsap, K. W., Bos, R., van der Mei, H. C., et al. (2001) · Antonie van Leeuwenhoek · doi:10.1023/a:1012013101862 · Cited by 34 · see citing works
Susceptibility Testing of Fungi and Correlation with Clinical Outcome
Ghannoum, M. A. (1997) · Journal of Chemotherapy · doi:10.1080/1120009x.1997.12113186 · Cited by 33 · see citing works
Rapid diagnosis of fungal infection of intravascular catheters in newborns by scanning electron microscopy
Sbarbati, A., Fanos, V., Bernardi, P., & Tatò, L. (2001) · Scanning · doi:10.1002/sca.4950230604 · Cited by 11 · see citing works

Flagged first, then by citations

Sorted by citations

Candida species: current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options
Sardi, J. C. O., Scorzoni, L., Bernardi, T., Fusco-Almeida, A. M., & Mendes Giannini, M. J. S. (2013) · Journal of Medical Microbiology · doi:10.1099/jmm.0.045054-0 · Cited by 1,184 · see citing works
Candida albicans Biofilms and Human Disease
Nobile, C. J., & Johnson, A. D. (2015) · Annual Review of Microbiology · doi:10.1146/annurev-micro-091014-104330 · Cited by 1,057 · see citing works
A simple and reproducible 96-well plate-based method for the formation of fungal biofilms and its application to antifungal susceptibility testing
Pierce, C. G., Uppuluri, P., Tristan, A. R., Wormley, F. L., Mowat, E., Ramage, G., & Lopez-Ribot, J. L. (2008) · Nature Protocols · doi:10.1038/nprot.2008.141 · Cited by 1,041 · see citing works
Self-citation
Emerging opportunistic yeast infections
Miceli, M. H., Díaz, J. A., & Lee, S. A. (2011) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(10)70218-8 · Cited by 811 · see citing works
Candida biofilms on implanted biomaterials: a clinically significant problem
Ramage, G., MartÃnez, J. P., & LÃ³pez-Ribot, J. L. (2006) · FEMS Yeast Research · doi:10.1111/j.1567-1364.2006.00117.x · Cited by 575 · see citing works
Self-citation
Regulatory circuitry governing fungal development, drug resistance, and disease.
Shapiro, R. S., Robbins, N., & Cowen, L. E. (2011) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00045-10 · Cited by 576 · see citing works
Candida albicans Biofilms Produce Antifungal-Tolerant Persister Cells
LaFleur, M. D., Kumamoto, C. A., & Lewis, K. (2006) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00684-06 · Cited by 521 · see citing works
Critical Role of Bcr1-Dependent Adhesins in C. albicans Biofilm Formation In Vitro and In Vivo
Nobile, C. J., Andes, D. R., Nett, J. E., Smith, F. J., Yue, F., Phan, Q.-T., Edwards, J. E., Filler, S. G., & Mitchell, A. P. (2006) · PLoS Pathogens · doi:10.1371/journal.ppat.0020063 · Cited by 507 · see citing works
Our Current Understanding of Fungal Biofilms
Ramage, G., Mowat, E., Jones, B., Williams, C., & Lopez-Ribot, J. (2009) · Critical Reviews in Microbiology · doi:10.3109/10408410903241436 · Cited by 483 · see citing works
Self-citation
Dispersion as an Important Step in the Candida albicans Biofilm Developmental Cycle
Uppuluri, P., Chaturvedi, A. K., Srinivasan, A., Banerjee, M., Ramasubramaniam, A. K., Köhler, J. R., Kadosh, D., & Lopez-Ribot, J. L. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1000828 · Cited by 432 · see citing works
Self-citation
Mechanisms of Candida Biofilm Drug Resistance
Taff, H. T., Mitchell, K. F., Edward, J. A., & Andes, D. R. (2013) · Future Microbiology · doi:10.2217/fmb.13.101 · Cited by 422 · see citing works
Putative Role of β-1,3 Glucans in Candida albicans Biofilm Resistance
Nett, J., Lincoln, L., Marchillo, K., Massey, R., Holoyda, K., Hoff, B., VanHandel, M., & Andes, D. (2007) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01056-06 · Cited by 407 · see citing works
Biofilm Production by Candida Species and Inadequate Antifungal Therapy as Predictors of Mortality for Patients with Candidemia
Tumbarello, M., Posteraro, B., Trecarichi, E. M., Fiori, B., Rossi, M., Porta, R., de Gaetano Donati, K., La Sorda, M., Spanu, T., Fadda, G., et al. (2007) · Journal of Clinical Microbiology · doi:10.1128/jcm.00131-07 · Cited by 343 · see citing works
Effect of silver nanoparticles on Candida albicans biofilms: an ultrastructural study
Lara, H. H., Romero-Urbina, D. G., Pierce, C., Lopez-Ribot, J. L., Arellano-Jiménez, M. J., & Jose-Yacaman, M. (2015) · Journal of Nanobiotechnology · doi:10.1186/s12951-015-0147-8 · Cited by 323 · see citing works
Self-citation
A Candida Biofilm-Induced Pathway for Matrix Glucan Delivery: Implications for Drug Resistance
Taff, H. T., Nett, J. E., Zarnowski, R., Ross, K. M., Sanchez, H., Cain, M. T., Hamaker, J., Mitchell, A. P., & Andes, D. R. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1002848 · Cited by 291 · see citing works
Development of a simple model for studying the effects of antifungal agents on multicellular communities of Aspergillus fumigatus
Mowat, E., Butcher, J., Lang, S., Williams, C., & Ramage, G. (2007) · Journal of Medical Microbiology · doi:10.1099/jmm.0.47247-0 · Cited by 259 · see citing works
Self-citation
Presence of Extracellular DNA in the Candida albicans Biofilm Matrix and its Contribution to Biofilms
Martins, M., Uppuluri, P., Thomas, D. P., Cleary, I. A., Henriques, M., Lopez-Ribot, J. L., & Oliveira, R. (2010) · Mycopathologia · doi:10.1007/s11046-009-9264-y · Cited by 250 · see citing works
Self-citation
Fungal Biofilms, Drug Resistance, and Recurrent Infection
Desai, J. V., Mitchell, A. P., & Andes, D. R. (2014) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a019729 · Cited by 252 · see citing works
Aspergillus fumigatus Forms Biofilms with Reduced Antifungal Drug Susceptibility on Bronchial Epithelial Cells
Seidler, M. J., Salvenmoser, S., & Müller, F.-M. C. (2008) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00234-08 · Cited by 229 · see citing works
Candida albicans mannans mediate Streptococcus mutans exoenzyme GtfB binding to modulate cross-kingdom biofilm development in vivo
Hwang, G., Liu, Y., Kim, D., Li, Y., Krysan, D. J., & Koo, H. (2017) · PLOS Pathogens · doi:10.1371/journal.ppat.1006407 · Cited by 214 · see citing works
Candida albicans biofilm development, modeling a host–pathogen interaction
Nett, J., & Andes, D. (2006) · Current Opinion in Microbiology · doi:10.1016/j.mib.2006.06.007 · Cited by 210 · see citing works
Candida parapsilosis Is a Significant Neonatal Pathogen: A Systematic Review and Meta-analysis
Pammi, M., Holland, L., Butler, G., Gacser, A., & Bliss, J. M. (2013) · Pediatric Infectious Disease Journal · doi:10.1097/inf.0b013e3182863a1c · Cited by 206 · see citing works
Silver colloidal nanoparticles: antifungal effect against adhered cells and biofilms ofCandida albicansandCandida glabrata
Monteiro, D. R., Gorup, L. F., Silva, S., Negri, M., de Camargo, E. R., Oliveira, R., Barbosa, D. B., & Henriques, M. (2011) · Biofouling · doi:10.1080/08927014.2011.599101 · Cited by 205 · see citing works
In vitro antifungal activity of hydroxychavicol isolated from Piper betle L
Ali, I., Khan, F. G., Suri, K. A., Gupta, B. D., Satti, N. K., Dutt, P., Afrin, F., Qazi, G. N., & Khan, I. A. (2010) · Annals of Clinical Microbiology and Antimicrobials · doi:10.1186/1476-0711-9-7 · Cited by 176 · see citing works
Antifungal therapy with an emphasis on biofilms
Pierce, C. G., Srinivasan, A., Uppuluri, P., Ramasubramanian, A. K., & López-Ribot, J. L. (2013) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2013.08.008 · Cited by 173 · see citing works
E1210, a New Broad-Spectrum Antifungal, Suppresses Candida albicans Hyphal Growth through Inhibition of Glycosylphosphatidylinositol Biosynthesis
Watanabe, N.-A., Miyazaki, M., Horii, T., Sagane, K., Tsukahara, K., & Hata, K. (2012) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00731-11 · Cited by 169 · see citing works
Comparison of the photodynamic fungicidal efficacy of methylene blue, toluidine blue, malachite green and low-power laser irradiation alone against Candida albicans
Souza, R. C., Junqueira, J. C., Rossoni, R. D., Pereira, C. A., Munin, E., & Jorge, A. O. C. (2010) · Lasers in Medical Science · doi:10.1007/s10103-009-0706-z · Cited by 167 · see citing works
Time Course Global Gene Expression Analysis of an In VivoCandidaBiofilm
Nett, J. E., Lepak, A. J., Marchillo, K., & Andes, D. R. (2009) · The Journal of Infectious Diseases · doi:10.1086/599838 · Cited by 162 · see citing works
Contribution of the glycolytic flux and hypoxia adaptation to efficient biofilm formation by Candida albicans
Bonhomme, J., Chauvel, M., Goyard, S., Roux, P., Rossignol, T., & d'Enfert, C. (2011) · Molecular Microbiology · doi:10.1111/j.1365-2958.2011.07626.x · Cited by 144 · see citing works
Association of subgingival colonization of <scp>C</scp>andida albicans and other yeasts with severity of chronic periodontitis
Canabarro, A., Valle, C., Farias, M. R., Santos, F. B., Lazera, M., & Wanke, B. (2013) · Journal of Periodontal Research · doi:10.1111/jre.12022 · Cited by 140 · see citing works
Aspergillus biofilms: clinical and industrial significance
Ramage, G., Rajendran, R., Gutierrez-Correa, M., Jones, B., & Williams, C. (2011) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2011.02381.x · Cited by 136 · see citing works
Self-citation
Antifungal lock therapy
Walraven, C. J., & Lee, S. A. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01351-12 · Cited by 132 · see citing works
The characteristics of Aspergillus fumigatus mycetoma development: is this a biofilm?
Mowat, E., Williams, C., Jones, B., Mcchlery, S., & Ramage, G. (2009) · Medical Mycology · doi:10.1080/13693780802238834 · Cited by 131 · see citing works
Self-citation
Biofilm formation byAspergillus fumigatus
Kaur, S., & Singh, S. (2013) · Medical Mycology · doi:10.3109/13693786.2013.819592 · Cited by 128 · see citing works
Aspergillus fumigatusbiofilms in the clinical setting
Müller, F.-M. C., Seidler, M., & Beauvais, A. (2011) · Medical Mycology · doi:10.3109/13693786.2010.502190 · Cited by 123 · see citing works
Antifungal activity of gemini quaternary ammonium salts
Obłąk, E., Piecuch, A., Krasowska, A., & Łuczyński, J. (2013) · Microbiological Research · doi:10.1016/j.micres.2013.06.001 · Cited by 119 · see citing works
High-throughput screening of a collection of known pharmacologically active small compounds for identification of candida albicans biofilm inhibitors
Siles, S. A., Srinivasan, A., Pierce, C. G., Lopez-Ribot, J. L., & Ramasubramanian, A. K. (2013) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00680-13 · Cited by 120 · see citing works
Self-citation
Distribution of Candida albicans and non-albicans Candida species in oral candidiasis patients: correlation between cell surface hydrophobicity and biofilm forming activities
Muadcheingka, T., & Tantivitayakul, P. (2015) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2015.03.002 · Cited by 120 · see citing works
Inhibition of Candida auris Biofilm Formation on Medical and Environmental Surfaces by Silver Nanoparticles
Lara, H. H., Ixtepan-Turrent, L., Jose Yacaman, M., & Lopez-Ribot, J. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b20708 · Cited by 116 · see citing works
Self-citation
Proteomics for the analysis of the Candida albicans biofilm lifestyle
Thomas, D. P., Bachmann, S. P., & Lopez‐Ribot, J. L. (2006) · PROTEOMICS · doi:10.1002/pmic.200600332 · Cited by 117 · see citing works
Self-citation
The Transcriptional Regulator Nrg1p Controls Candida albicans Biofilm Formation and Dispersion
Uppuluri, P., Pierce, C. G., Thomas, D. P., Bubeck, S. S., Saville, S. P., & Lopez-Ribot, J. L. (2010) · Eukaryotic Cell · doi:10.1128/ec.00111-10 · Cited by 110 · see citing works
Self-citation
Candida albicans biofilm formation is associated with increased anti‐oxidative capacities
Seneviratne, C. J., Wang, Y., Jin, L., Abiko, Y., & Samaranayake, L. P. (2008) · PROTEOMICS · doi:10.1002/pmic.200701097 · Cited by 104 · see citing works
A Small Subpopulation of Blastospores in Candida albicans Biofilms Exhibit Resistance to Amphotericin B Associated with Differential Regulation of Ergosterol and β -1,6-Glucan Pathway Genes
Khot, P. D., Suci, P. A., Miller, R. L., Nelson, R. D., & Tyler, B. J. (2006) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00997-06 · Cited by 104 · see citing works
Antifungal Activity of Phenolic Compounds Identified in Flowers from North Eastern Portugal Against Candida Species
Alves, C. T., Ferreira, I. C., Barros, L., Silva, S., Azeredo, J., & Henriques, M. (2014) · Future Microbiology · doi:10.2217/fmb.13.147 · Cited by 102 · see citing works
Photodynamic therapy of oral Candida infection in a mouse model
Freire, F., Ferraresi, C., Jorge, A. O. C., & Hamblin, M. R. (2016) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2016.03.049 · Cited by 103 · see citing works
The effect of silver nanoparticles and nystatin on mixed biofilms ofCandida glabrataandCandida albicanson acrylic
Silva, S., Pires, P., Monteiro, D. R., Negri, M., Gorup, L. F., Camargo, E. R., Barbosa, D. B., Oliveira, R., Williams, D. W., Henriques, M., et al. (2013) · Medical Mycology · doi:10.3109/13693786.2012.700492 · Cited by 101 · see citing works
Absence of Amphotericin B-Tolerant Persister Cells in Biofilms of Some Candida Species
Al-Dhaheri, R. S., & Douglas, L. J. (2008) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01473-07 · Cited by 99 · see citing works
Biofilm Formation by Pneumocystis spp
Cushion, M. T., Collins, M. S., & Linke, M. J. (2009) · Eukaryotic Cell · doi:10.1128/ec.00202-08 · Cited by 96 · see citing works
Apoptosis in Candida biofilms exposed to amphotericin B
Al-Dhaheri, R. S., & Douglas, L. J. (2010) · Journal of Medical Microbiology · doi:10.1099/jmm.0.015784-0 · Cited by 81 · see citing works
Candida Species: New Insights into Biofilm Formation
Cuéllar-Cruz, M., López-Romero, E., Villagómez-Castro, J. C., & Ruiz-Baca, E. (2012) · Future Microbiology · doi:10.2217/fmb.12.48 · Cited by 80 · see citing works
Exopolysaccharide analysis of biofilm‐forming Candida albicans
Lal, P., Sharma, D., Pruthi, P., & Pruthi, V. (2010) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2009.04634.x · Cited by 76 · see citing works
Proteomics of drug resistance in Candida glabrata biofilms
Seneviratne, C. J., Wang, Y., Jin, L., Abiko, Y., & Samaranayake, L. P. (2010) · PROTEOMICS · doi:10.1002/pmic.200900611 · Cited by 74 · see citing works
The role of antifungals against Candida biofilm in catheter-related candidemia
Bouza, E., Guinea, J., & Guembe, M. (2014) · Antibiotics · doi:10.3390/antibiotics4010001 · Cited by 62 · see citing works
Novel high-throughput screen against Candida albicans identifies antifungal potentiators and agents effective against biofilms
LaFleur, M. D., Lucumi, E., Napper, A. D., Diamond, S. L., & Lewis, K. (2011) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkq530 · Cited by 59 · see citing works
Pseudomonas aeruginosa lipopolysaccharide inhibits <scp>C</scp>andida albicans hyphae formation and alters gene expression during biofilm development
Bandara, H. M. H. N., K Cheung, B. P., Watt, R. M., Jin, L. J., & Samaranayake, L. P. (2013) · Molecular Oral Microbiology · doi:10.1111/omi.12006 · Cited by 57 · see citing works
Synergistic effects of tea catechin epigallocatechin gallate and antimycotics against oral Candida species
Ning, Y., Ling, J., & Wu, C. D. (2015) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2015.07.001 · Cited by 56 · see citing works
Antifungal therapy of Candida biofilms: Past, present and future
Ajetunmobi, O. H., Badali, H., Romo, J. A., Ramage, G., & Lopez-Ribot, J. L. (2023) · Biofilm · doi:10.1016/j.bioflm.2023.100126 · Cited by 52 · see citing works
Self-citation
Repurposing antipsychotic drugs into antifungal agents: Synergistic combinations of azoles and bromperidol derivatives in the treatment of various fungal infections
Holbrook, S. Y. L., Garzan, A., Dennis, E. K., Shrestha, S. K., & Garneau-Tsodikova, S. (2017) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2017.07.030 · Cited by 51 · see citing works
Candida glabrata susceptibility to antifungals and phagocytosis is modulated by acetate
Mota, S., Alves, R., Carneiro, C., Silva, S., Brown, A. J., Istel, F., Kuchler, K., Sampaio, P., Casal, M., Henriques, M., et al. (2015) · Frontiers in Microbiology · doi:10.3389/fmicb.2015.00919 · Cited by 49 · see citing works
Efficacy of surface-generated nitric oxide againstCandida albicansadhesion and biofilm formation
Privett, B. J., Nutz, S. T., & Schoenfisch, M. H. (2010) · Biofouling · doi:10.1080/08927014.2010.534552 · Cited by 45 · see citing works
Comparative Ploidy Proteomics of Candida albicans Biofilms Unraveled the Role of the AHP1 Gene in the Biofilm Persistence Against Amphotericin B
Truong, T., Zeng, G., Qingsong, L., Kwang, L. T., Tong, C., Chan, F. Y., Wang, Y., & Seneviratne, C. J. (2016) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m116.061523 · Cited by 45 · see citing works
Susceptibility of Pneumocystis to Echinocandins in Suspension and Biofilm Cultures
Cushion, M. T., & Collins, M. S. (2011) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00017-11 · Cited by 38 · see citing works
Candida albicans Biofilms Are Generally Devoid of Persister Cells
Denega, I., d’Enfert, C., & Bachellier-Bassi, S. (2019) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01979-18 · Cited by 32 · see citing works
Biofilm production and antibiofilm activity of echinocandins and liposomal amphotericin B in echinocandin-resistant yeast species
Marcos-Zambrano, L. J., Gómez-Perosanz, M., Escribano, P., Zaragoza, O., Bouza, E., & Guinea, J. (2016) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.03065-15 · Cited by 28 · see citing works
In vitro analysis of flufenamic acid activity against Candida albicans biofilms
Chavez-Dozal, A. A., Jahng, M., Rane, H. S., Asare, K., Kulkarny, V. V., Bernardo, S. M., & Lee, S. A. (2014) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2013.08.018 · Cited by 26 · see citing works
SAGA Complex Subunits in Candida albicans Differentially Regulate Filamentation, Invasiveness, and Biofilm Formation
Rashid, S., Correia-Mesquita, T. O., Godoy, P., Omran, R. P., & Whiteway, M. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.764711 · Cited by 15 · see citing works
Anticandidal Activity of Kalopanaxsaponin A: Effect on Proliferation, Cell Morphology, and Key Virulence Attributes of Candida albicans
Li, Y., Shan, M., Yan, M., Yao, H., Wang, Y., Gu, B., Zhu, Z., & Li, H. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.02844 · Cited by 16 · see citing works
(PhSe) 2 and ( p Cl-PhSe) 2 organochalcogen compounds inhibit Candida albicans adhesion to human endocervical (HeLa) cells and show anti-biofilm activities
da Silva, B. M., Braga, M. T., da Silva Passos, J. C., Carvalho, M. L., Rosseti, I. B., de Amorim, L. M. M., da Rocha, J. B. T., Alberto-Silva, C., & Costa, M. S. (2021) · Biofouling · doi:10.1080/08927014.2021.1897110 · Cited by 7 · see citing works
Inhibition of nucleic acid biosynthesis makes little difference to formation of amphotericin B-tolerant persisters in Candida albicans biofilm
Sun, J., Liu, X., Jiang, G., & Qi, Q. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.03765-14 · Cited by 6 · see citing works

Influence of Al(III) on biofilm and its extracellular polymeric substances in sequencing batch biofilm reactors
Hu, X., Yang, L., Lai, X., et al. (2017) · Environmental Technology · doi:10.1080/09593330.2017.1378268 · Cited by 15 · see citing works
Biofilms on instruments and environmental surfaces: Do they interfere with instrument reprocessing and surface disinfection? Review of the literature
Alfa, M. J. (2019) · American Journal of Infection Control · doi:10.1016/j.ajic.2019.02.027 · Cited by 48 · see citing works
Biofilms, Microbial
Bryers, J. D. (1999) · Encyclopedia of Bioprocess Technology · doi:10.1002/0471250589.ebt027
Insight into mature biofilm quorum sensing in full-scale wastewater treatment plants
Wang, J., Liu, Q., Hu, H., et al. (2019) · Chemosphere · doi:10.1016/j.chemosphere.2019.06.007 · Cited by 29 · see citing works
The effect of hydrophobicity of group a beta-hemolytic streptococcus in the process of adherence and biofilm production
Šmitran, A., Markovic, T., & Ranin, L. T. (2014) · Srpski arhiv za celokupno lekarstvo · doi:10.2298/sarh1410557s

Authors: Ramage, G., Saville, S. P., Thomas, D. P., & López-Ribot, J. L.
Affiliations: Glasgow Caledonian University (GB)
The University of Texas at San Antonio Health Science Center (US)
Department of Medicine, Division of Infectious Diseases, The University of Texas Health Science Center at San Antonio, San Antonio, Texas
ORCID: Ramage, Gordon
Thomas, Derek P.
Venue: Eukaryotic Cell
Publisher: American Society for Microbiology
Published: 2005-04
Volume: 4
Issue: 4
Pages: 633-638
ISSN: 1535-9778 (ISSN-L)
1535-9786
DOI: 10.1128/ec.4.4.633-638.2005
PMC: PMC1087806
OpenAlex: W2007581658
Cited by: 678
References: 89
Citations by year: 2026: 13 · 2025: 15 · 2024: 21 · 2023: 12 · 2022: 34 · 2021: 28 · 2020: 37 · 2019: 38 · 2018: 38 · 2017: 44 · 2016: 48 · 2015: 43 · 2014: 40 · 2013: 53 · 2012: 44
FWCI: 3.38
Type: journal article
Language: en
Open access: diamond
doi.org
Licence: journals.asm.org/non-commercial-tdm-license (tdm)
Locations: Eukaryotic Cell (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed (publishedVersion)
PubMed Central (publishedVersion)
ResearchOnline (Glasgow Caledonian University) (acceptedVersion)
ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (submittedVersion)
Funders: Burroughs Wellcome Fund
Texas Higher Education Coordinating Board
National Institutes of Health
Topics: Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bacterial biofilms and quorum sensing
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Fungal and yeast genetics research
Keywords: Candida, biofilm, exopolysaccharide matrix, planktonic versus biofilm growth, fungal infection, biofilm-associated infections, yeast physiology
MeSH terms: Candida, Candidiasis, Drug Resistance, Microbial, Models, Biological, Biofilms

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Candida Biofilms: an Update

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks