The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Angiotensin-I-Converting Enzyme (ACE) Inhibitors from Marine Resources: Prospects in the Pharmaceutical Industry
Open accessAbstract
Hypertension or high blood pressure is one of the major independent risk factors for cardiovascular diseases. Angiotensin-I-converting enzyme (EC 3.4.15.1; ACE) plays an important physiological role in regulation of blood pressure by converting angiotensin I to angiotensin II, a potent vasoconstrictor. Therefore, the inhibition of ACE activity is a major target in the prevention of hypertension. Recently, the search for natural ACE inhibitors as alternatives to synthetic drugs is of great interest to prevent several side effects and a number of novel compounds such as bioactive peptides, chitooligosaccharide derivatives (COS) and phlorotannins have been derived from marine organisms as potential ACE inhibitors. These inhibitory derivatives can be developed as nutraceuticals and pharmaceuticals with potential to prevent hypertension. Hence, the aim of this review is to discuss the marine-derived ACE inhibitors and their future prospects as novel therapeutic drug candidates for treat hypertension.
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Sheih, I.-C., Fang, T. J., & Wu, T.-K. (2009) · Food Chemistry · doi:10.1016/j.foodchem.2008.12.019 · Cited by 280
Cited by
Wijesekara, I., Pangestuti, R., & Kim, S.-K. (2011) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2010.10.062 · Cited by 992
Phlorotannins as bioactive agents from brown algae
Li, Y.-X., Wijesekara, I., Li, Y., & Kim, S.-K. (2011) · Process Biochemistry · doi:10.1016/j.procbio.2011.09.015 · Cited by 475
Self-citationFunctional and bioactive properties of fish protein hydolysates and peptides: A comprehensive review
Halim, N. R. A., Yusof, H. M., & Sarbon, N. M. (2016) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2016.02.007 · Cited by 429
Roohinejad, S., Koubaa, M., Barba, F. J., Saljoughian, S., Amid, M., & Greiner, R. (2017) · Food Research International · doi:10.1016/j.foodres.2016.08.016 · Cited by 360
Admassu, H., Gasmalla, M. A. A., Yang, R., & Zhao, W. (2018) · Journal of Food Science · doi:10.1111/1750-3841.14011 · Cited by 293
Metadata
- Authors
- Wijesekara, I., & Kim, S.-K.
- Venue
- Marine Drugs
- Publisher
- MDPI AG
- Published
- 2010-03-31
- Volume
- 8
- Issue
- 4
- Pages
- 1080-1093
- ISSN
- 1660-3397 (ISSN-L)
- OpenAlex
- W2157618308
- Cited by
- 356
- References
- 1
- FWCI
- 8.86
- Type
- journal article
- Language
- en
- Open access
- gold
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- Wijesekara, I., & Kim, S.-K. (2010). Angiotensin-I-Converting Enzyme (ACE) Inhibitors from Marine Resources: Prospects in the Pharmaceutical Industry. Marine Drugs. https://doi.org/10.3390/md8041080
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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