The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
The Production and Delivery of Probiotics: A Review of a Practical Approach
Open accessAbstract
To successfully deliver probiotic benefits to the consumer, several criteria must be met. Here, we discuss the often-forgotten challenges in manufacturing the strains and incorporating them in consumer products that provide the required dose at the end of shelf life. For manufacturing, an intricate production process is required that ensures both high yield and stability and must also be able to meet requirements such as the absence of specific allergens, which precludes some obvious culture media ingredients. Reproducibility is important to ensure constant high performance and quality. To ensure this, quality control throughout the whole production process, from raw materials to the final product, is essential, as is the documentation of this quality control. Consumer product formulation requires extensive skill and experience. Traditionally, probiotic lactic acid bacteria and bifidobacteria have been incorporated in fermented dairy products, with limited shelf life and refrigerated storage. Currently, probiotics may be incorporated in dietary supplements and other “dry” food matrices which are expected to have up to 24 months of stability at ambient temperature and humidity. With the right choice of production process, product formulation, and strains, high-quality probiotics can be successfully included in a wide variety of delivery formats to suit consumer requirements.
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Hill (2014) · doi:10.1038/nrgastro.2014.66 · Cited by 9,592
Barrangou, R., Briczinski, E. P., Traeger, L. L., Loquasto, J. R., Richards, M., Horvath, P., Coûté-Monvoisin, A.-C., Leyer, G., Rendulic, S., Steele, J. L., et al. (2009) · Journal of Bacteriology · doi:10.1128/jb.00155-09 · Cited by 150
Probiotic use in at-risk populations
Sanders, M. E., Merenstein, D. J., Ouwehand, A. C., Reid, G., Salminen, S., Cabana, M. D., Paraskevakos, G., & Leyer, G. (2016) · Journal of the American Pharmacists Association · doi:10.1016/j.japh.2016.07.001 · Cited by 129
Self-citationJohnston, B. C., Lytvyn, L., Lo, C. K.-F., Allen, S. J., Wang, D., Szajewska, H., Miller, M., Ehrhardt, S., Sampalis, J., Duman, D. G., et al. (2018) · Infection Control & Hospital Epidemiology · doi:10.1017/ice.2018.84 · Cited by 50
Cited by
Probiotics Mechanism of Action on Immune Cells and Beneficial Effects on Human Health
Mazziotta, C., Tognon, M., Martini, F., Torreggiani, E., & Rotondo, J. C. (2023) · Cells · doi:10.3390/cells12010184 · Cited by 889
Probiotics: mechanism of action, health benefits and their application in food industries
Latif, A., Shehzad, A., Niazi, S., Zahid, A., Ashraf, W., Iqbal, M. W., Rehman, A., Riaz, T., Aadil, R. M., Khan, I. M., et al. (2023) · Frontiers in Microbiology · doi:10.3389/fmicb.2023.1216674 · Cited by 623
Encapsulation of probiotics and nutraceuticals: Applications in functional food industry
Reque, P. M., & Brandelli, A. (2021) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2021.05.022 · Cited by 336
Probiotics for Constipation in Parkinson Disease: A Randomized Placebo-Controlled Study
Tan, A. H., Lim, S.-Y., Chong, K. K., A Manap, M. A. A., Hor, J. W., Lim, J. L., Low, S. C., Chong, C. W., Mahadeva, S., & Lang, A. E. (2021) · Neurology · doi:10.1212/wnl.0000000000010998 · Cited by 226
Use of Probiotics in Preterm Infants
Poindexter, B., COMMITTEE ON FETUS AND NEWBORN, Cummings, J., Hand, I., Adams-Chapman, I., Aucott, S. W., Puopolo, K. M., Goldsmith, J. P., Kaufman, D., Martin, C., et al. (2021) · Pediatrics · doi:10.1542/peds.2021-051485 · Cited by 171
Metadata
- Authors
- Fenster, K., Freeburg, B., Hollard, C., Wong, C., Rønhave Laursen, R., & Ouwehand, A. C.
- Venue
- Microorganisms
- Publisher
- MDPI AG
- Published
- 2019-03-17
- Volume
- 7
- Issue
- 3
- Pages
- 83
- ISSN
- 2076-2607 (ISSN-L)
- OpenAlex
- W2921856608
- Cited by
- 405
- References
- 4
- FWCI
- 29.04
- Type
- journal article
- Language
- en
- Open access
- gold
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- Fenster, K., Freeburg, B., Hollard, C., Wong, C., Rønhave Laursen, R., & Ouwehand, A. C. (2019). The Production and Delivery of Probiotics: A Review of a Practical Approach. Microorganisms. https://doi.org/10.3390/microorganisms7030083
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
