The DOI matches its Crossref record; 129 of the 129 references it cites were found in a registry or an index.
Probiotics: mechanism of action, health benefits and their application in food industries
Open accessAbstract
Probiotics, like lactic acid bacteria, are non-pathogenic microbes that exert health benefits to the host when administered in adequate quantity. Currently, research is being conducted on the molecular events and applications of probiotics. The suggested mechanisms by which probiotics exert their action include; competitive exclusion of pathogens for adhesion sites, improvement of the intestinal mucosal barrier, gut immunomodulation, and neurotransmitter synthesis. This review emphasizes the recent advances in the health benefits of probiotics and the emerging applications of probiotics in the food industry. Due to their capability to modulate gut microbiota and attenuate the immune system, probiotics could be used as an adjuvant in hypertension, hypercholesterolemia, cancer, and gastrointestinal diseases. Considering the functional properties, probiotics are being used in the dairy, beverage, and baking industries. After developing the latest techniques by researchers, probiotics can now survive within harsh processing conditions and withstand GI stresses quite effectively. Thus, the potential of probiotics can efficiently be utilized on a commercial scale in food processing industries.
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Cites
Hill (2014) · doi:10.1038/nrgastro.2014.66 · Cited by 9,592
Health benefits of fermented foods: Microbiota and beyond
Marco, M. L., Heeney, D., Binda, S., Cifelli, C. J., Cotter, P. D., Foligné, B., Gänzle, M., Kort, R., Pasin, G., Pihlanto, A., et al. (2017) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2016.11.010 · Cited by 1,674
Mechanisms of action of probiotics
Plaza-Diaz, J., Ruiz-Ojeda, F. J., Gil-Campos, M., & Gil, A. (2019) · Advances in Nutrition · doi:10.1093/advances/nmy063 · Cited by 1,423
Probiotics modulated gut microbiota suppresses hepatocellular carcinoma growth in mice
Li, J., Sung, C. Y. J., Lee, N., Ni, Y., Pihlajamäki, J., Panagiotou, G., & El-Nezami, H. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1518189113 · Cited by 626
Prebiotics as functional foods: A review
Al-Sheraji, S. H., Ismail, A., Manap, M. Y., Mustafa, S., Yusof, R. M., & Hassan, F. A. (2013) · Journal of Functional Foods · doi:10.1016/j.jff.2013.08.009 · Cited by 581
Fiocchi, A., Pawankar, R., Cuello-Garcia, C., Ahn, K., Al-Hammadi, S., Agarwal, A., Beyer, K., Burks, W., Canonica, G. W., Ebisawa, M., et al. (2015) · World Allergy Organization Journal · doi:10.1186/s40413-015-0055-2 · Cited by 473
The Production and Delivery of Probiotics: A Review of a Practical Approach
Fenster, K., Freeburg, B., Hollard, C., Wong, C., Rønhave Laursen, R., & Ouwehand, A. C. (2019) · Microorganisms · doi:10.3390/microorganisms7030083 · Cited by 405
Encapsulation of probiotics and nutraceuticals: Applications in functional food industry
Reque, P. M., & Brandelli, A. (2021) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2021.05.022 · Cited by 336
Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis
Konishi, H., Fujiya, M., Tanaka, H., Ueno, N., Moriichi, K., Sasajima, J., Ikuta, K., Akutsu, H., Tanabe, H., & Kohgo, Y. (2016) · Nature Communications · doi:10.1038/ncomms12365 · Cited by 287
Probiotics, Prebiotics, and Phytogenic Substances for Optimizing Gut Health in Poultry
Shehata, A. A., Yalçın, S., Latorre, J. D., Basiouni, S., Attia, Y. A., Abd El-Wahab, A., Visscher, C., El-Seedi, H. R., Huber, C., Hafez, H. M., et al. (2022) · Microorganisms · doi:10.3390/microorganisms10020395 · Cited by 285
Cited by
Probiotic Functions in Fermented Foods: Anti-Viral, Immunomodulatory, and Anti-Cancer Benefits
Pyo, Y., Kwon, K. H., & Jung, Y. J. (2024) · Foods · doi:10.3390/foods13152386 · Cited by 66
Wei, J., Liu, C., Qin, D., Ren, F., Duan, J., Chen, T., & Wu, A. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102544 · Cited by 15
Liu, Y., Zheng, H., Wang, J., Xin, J., Wu, R., Zhang, J., Zhong, Z., Liu, H., Huang, Y., Fu, H., et al. (2025) · BMC Microbiology · doi:10.1186/s12866-025-04099-w · Cited by 9
The Impact of Probiotics on Acne Vulgaris: A Meta-Analysis of Randomized Controlled Trials
Mohamed, M., Ullah, A., Hassan, R., Hamza, M., Mohamed, I., & Salam, M. (2025) · Cureus · doi:10.7759/cureus.97010 · Cited by 5
Kerek, Á., Palkovicsné Pézsa, N., Kaszab, E., Jerzsele, Á., & Farkas, O. (2025) · Frontiers in Veterinary Science · doi:10.3389/fvets.2025.1684650 · Cited by 4
Metadata
- Authors
- Latif, A., Shehzad, A., Niazi, S., Zahid, A., Ashraf, W., Iqbal, M. W., Rehman, A., Riaz, T., Aadil, R. M., Khan, I. M., Özogul, F., Rocha, J. M., Esatbeyoglu, T., & Korma, S. A.
- Venue
- Frontiers in Microbiology
- Publisher
- Frontiers Media SA
- Published
- 2023-08-17
- Volume
- 14
- Pages
- 1216674-1216674
- ISSN
- 1664-302X (ISSN-L)
- OpenAlex
- W4385985598
- Cited by
- 623
- References
- 129
- FWCI
- 79.62
- Type
- journal article
- Language
- en
- Open access
- gold
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- Latif, A., Shehzad, A., Niazi, S., Zahid, A., Ashraf, W., Iqbal, M. W., Rehman, A., Riaz, T., Aadil, R. M., Khan, I. M., Özogul, F., Rocha, J. M., Esatbeyoglu, T., & Korma, S. A. (2023). Probiotics: mechanism of action, health benefits and their application in food industries. Frontiers in Microbiology. https://doi.org/10.3389/fmicb.2023.1216674
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.