The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Biosynthesis and Genetic Regulation of Proanthocyanidins in Plants
Open accessAbstract
Proanthocyanidins (PAs), also known as condensed tannins, are a group of polyphenolic secondary metabolites synthesized in plants as oligomers or polymers of flavan-3-ol units via the flavonoid pathway. Due to their structural complexity and varied composition, only in the recent years has the study on the biosynthesis and regulation of PAs in plants taken off, although some details of the synthetic mechanism remain unclear. This paper aims to summarize the status of research on the structures of PAs in plants, the genes encoding key enzymes of biosynthetic pathway, the transport factors, the transcriptional regulation of PA biosynthesis and the genetic manipulation of PAs. The problems of this field were also discussed, including the nature of the final “enzyme” which catalyzes the polymerization reaction of PAs and the possible mechanism of how the elementary units of flavanols are assembled in vivo.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Antimicrobial properties of tannins
Scalbert, A. (1991) · Phytochemistry · doi:10.1016/0031-9422(91)83426-l · Cited by 2,321
Sharma, S. D., Meeran, S. M., & Katiyar, S. K. (2007) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-06-0661 · Cited by 219
Zhao, M., Yang, B., Wang, J., Liu, Y., Yu, L., & Jiang, Y. (2007) · International Immunopharmacology · doi:10.1016/j.intimp.2006.09.003 · Cited by 167
Comparison of proanthocyanidins in commercial antioxidants: Grape seed and pine bark extracts
Weber, H. A., Hodges, A. E., Guthrie, J. R., O'Brien, B. M., Robaugh, D., Clark, A. P., Harris, R. K., Algaier, J. W., & Smith, C. S. (2007) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf063150n · Cited by 151
Lalusin, A. G., Nishita, K., Kim, S.-H., Ohta, M., & Fujimura, T. (2006) · Molecular Genetics and Genomics · doi:10.1007/s00438-005-0080-x · Cited by 83
Cited by
Biosynthesis of Anthocyanins and Their Regulation in Colored Grapes
He, F., Mu, L., Yan, G.-L., Liang, N.-N., Pan, Q.-H., Wang, J., Reeves, M. J., & Duan, C.-Q. (2010) · Molecules · doi:10.3390/molecules15129057 · Cited by 615
Self-citationChitosan nanoparticles: A positive modulator of innate immune responses in plants
Chandra, S., Chakraborty, N., Dasgupta, A., Sarkar, J., Panda, K., & Acharya, K. (2015) · Scientific Reports · doi:10.1038/srep15195 · Cited by 422
A review of the chemistry of the genus Crataegus
Edwards, J. E., Brown, P. N., Talent, N., Dickinson, T. A., & Shipley, P. R. (2012) · Phytochemistry · doi:10.1016/j.phytochem.2012.04.006 · Cited by 280
Weseler, A. R., & Bast, A. (2017) · Nutrition Journal · doi:10.1186/s12937-016-0218-1 · Cited by 58
Effect of lignocellulose related compounds on microalgae growth and product biosynthesis: a review
Miazek, K., Remacle, C., Richel, A., & Goffin, D. (2014) · Energies · doi:10.3390/en7074446 · Cited by 50
Metadata
- Authors
- He, F., Pan, Q.-H., Shi, Y., & Duan, C.-Q.
- Venue
- Molecules
- Publisher
- MDPI AG
- Published
- 2008-10-28
- Volume
- 13
- Issue
- 10
- Pages
- 2674-2703
- ISSN
- 1420-3049 (ISSN-L)
- OpenAlex
- W2069622581
- Cited by
- 222
- References
- 5
- FWCI
- 2.11
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Biosynthesis and Genetic Regulation of Proanthocyanidins in Plants. https://app.cochat.ai/papers/10.3390/molecules13102674
- The paper
- He, F., Pan, Q.-H., Shi, Y., & Duan, C.-Q. (2008). Biosynthesis and Genetic Regulation of Proanthocyanidins in Plants. Molecules. https://doi.org/10.3390/molecules13102674
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
