The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Chemical Composition, Antibacterial Properties and Mechanism of Action of Essential Oil from Clove Buds against Staphylococcus aureus
Open accessAbstract
The essential oil of clove has a wide range of pharmacological and biological activities and is widely used in the medicine, fragrance and flavoring industries. In this work, 22 components of the essential oil obtained from clove buds were identified. Eugenol was the major component (76.23%). The essential oil exhibited strong antibacterial activity against Staphylococcus aureus ATCC 25923 with a minimum inhibitory concentration (MIC) of 0.625 mg/mL, and the antibacterial effects depended on its concentration and action time. Kill-time assays also confirmed the essential oil had a significant effect on the growth rate of surviving S. aureus. We hypothesized that the essential oil may interact with the cell wall and membrane first. On the one hand it destroys cell wall and membranes, next causing the losses of vital intracellular materials, which finally result in the bacterial death. Besides, essential oil penetrates to the cytoplasmic membrane or enters inside the cell after destruction of cell structure, and then inhibits the normal synthesis of DNA and proteins that are required for bacterial growth. These results suggested that the effects of the clove essential oil on the growth inhibition of S. aureus may be at the molecular level rather than only physical damage.
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Cites
Essential oils: Their antibacterial properties and potential applications in foods—A review
Burt, S. (2004) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2004.03.022 · Cited by 10,488
Dietary polyphenols and the prevention of diseases
Scalbert, A., Manach, C., Morand, C., Rémésy, C., & Jiménez, L. (2005) · Critical Reviews in Food Science and Nutrition · doi:10.1080/1040869059096 · Cited by 2,999
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Determining the Antimicrobial Actions of Tea Tree Oil
Cox, S. D., Mann, C. M., Markham, J. L., Gustafson, J. E., Warmington, J. R., & Wyllie, S. G. (2001) · Molecules · doi:10.3390/60100087 · Cited by 311
Cited by
Antibacterial and Antifungal Activities of Spices
Liu, Q., Meng, X., Li, Y., Zhao, C.-N., Tang, G.-Y., & Li, H.-B. (2017) · International Journal of Molecular Sciences · doi:10.3390/ijms18061283 · Cited by 435
Wang, X., Shen, Y., Thakur, K., Han, J., Zhang, J.-G., Hu, F., & Wei, Z.-J. (2020) · Molecules · doi:10.3390/molecules25173955 · Cited by 303
Kaur, K., Kaushal, S., & Rani, R. (2019) · Journal of Essential Oil Bearing Plants · doi:10.1080/0972060x.2019.1688689 · Cited by 91
Essential Oils as Potential Source of Anti‐Dandruff Agents: A Review
Arora, P., Nainwal, L. M., & Jain, S. (2022) · Combinatorial Chemistry & High Throughput Screening · doi:10.2174/1386207324666210712094148 · Cited by 23
Metadata
- Authors
- Xu, J.-G., Liu, T., Hu, Q.-P., & Cao, X.-M.
- Venue
- Molecules
- Publisher
- MDPI AG
- Published
- 2016-09-08
- Volume
- 21
- Issue
- 9
- Pages
- 1194
- ISSN
- 1420-3049 (ISSN-L)
- OpenAlex
- W2512008153
- Cited by
- 276
- References
- 5
- FWCI
- 14.89
- Type
- journal article
- Language
- en
- Open access
- gold
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- Xu, J.-G., Liu, T., Hu, Q.-P., & Cao, X.-M. (2016). Chemical Composition, Antibacterial Properties and Mechanism of Action of Essential Oil from Clove Buds against Staphylococcus aureus. Molecules. https://doi.org/10.3390/molecules21091194
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