Dietary polyphenols and the prevention of diseases

Scalbert, Augustin; Manach, Claudine; Morand, Christine; Rémésy, Christian; Jiménez, Liliana

doi:10.1080/1040869059096

Cited by 2,999Phytochemicals and Antioxidant ActivitiesNutritional Studies and DietAntioxidant Activity and Oxidative Stress

Dietary polyphenols and the prevention of diseases

Scalbert, Augustin, Manach, Claudine, Morand, Christine, Rémésy, Christian, Jiménez, Liliana·2005·Critical Reviews in Food Science and Nutrition

DOI 10.1080/1040869059096

Open this paper in CoChat — free account

Abstract

Polyphenols are the most abundant antioxidants in the diet and are widespread constituents of fruits, vegetables, cereals, dry legumes, chocolate, and beverages, such as tea, coffee, or wine. Experimental studies on animals or cultured human cell lines support a role of polyphenols in the prevention of cardiovascular diseases, cancers, neurodegenerative diseases, diabetes, or osteoporosis. However, it is very difficult to predict from these results the effects of polyphenol intake on disease prevention in humans. One of the reasons is that these studies have often been conducted at doses or concentrations far beyond those documented in humans. The few clinical studies on biomarkers of oxidative stress, cardiovascular disease risk factors, and tumor or bone resorption biomarkers have often led to contradictory results. Epidemiological studies have repeatedly shown an inverse association between the risk of myocardial infarction and the consumption of tea and wine or the intake level of some particular flavonoids, but no clear associations have been found between cancer risk and polyphenol consumption. More human studies are needed to provide clear evidence of their health protective effects and to better evaluate the risks possibly resulting from too high a polyphenol consumption.

Integrity signals

Registry

Crossref · 10.1080/1040869059096

Cites

304 of 304 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The Folin assay, commonly used to estimate total polyphenols in foods, has been applied to urine to compare polyphenol intake, but such use may be inappropriate because of interfering reducing metabolites.
“The Folin assay, commonly used to estimate total polyphenols in foods (46), has also been applied to urine samples to compare polyphenol intake (47), but such use may be inappropriate because of the presence of interfering reducing metabolites in such complex biological matrices (46).”
From The food metabolome: a window over dietary exposure (2014) · cites this paper as [46]

The Ferric Reducing Ability of Plasma (FRAP) as a Measure of “Antioxidant Power”: The FRAP Assay
Benzie, I. F. F., & Strain, J. (1996) · Analytical Biochemistry · doi:10.1006/abio.1996.0292 · Cited by 23,027 · see citing works
Structure-antioxidant activity relationships of flavonoids and phenolic acids
Rice-Evans, C. A., Miller, N. J., & Paganga, G. (1996) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(95)02227-9 · Cited by 9,085 · see citing works
Polyphenols: Food sources and bioavailability
Manach, C., Scalbert, A., Morand, C., Rémésy, C., & Jiménez, L. (2004) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/79.5.727 · Cited by 8,175 · see citing works
Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
Jang, M., Cai, L., Udeani, G. O., Slowing, K. V., Thomas, C. F., Beecher, C. W. W., Fong, H. H. S., Farnsworth, N. R., Kinghorn, A. D., Mehta, R. G., et al. (1997) · Science · doi:10.1126/science.275.5297.218 · Cited by 4,935 · cited 1× · see citing works
“[145] Jang, M.”
Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis
Celermajer, D. S., Sorensen, K. E., Gooch, V. M., Spiegelhalter, D. J., Miller, O. I., Sullivan, I. D., Lloyd, J. K., & Deanfield, J. E. (1992) · The Lancet · doi:10.1016/0140-6736(92)93147-f · Cited by 4,742 · see citing works
Interaction of Estrogenic Chemicals and Phytoestrogens with Estrogen Receptor β
Kuiper, G. G. J. M., Lemmen, J. G., Carlsson, B., Corton, J. C., Safe, S. H., van der Saag, P. T., van der Burg, B., & Gustafsson, J.-Å. (1998) · Endocrinology · doi:10.1210/endo.139.10.6216 · Cited by 4,203 · see citing works
Antioxidant Activity and Total Phenolics in Selected Fruits, Vegetables, and Grain Products
Velioğlu, Y. S., Mazza, G., Gao, L., & Oomah, B. D. (1998) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9801973 · Cited by 3,853 · see citing works
Dietary Intake and Bioavailability of Polyphenols
Scalbert, A., & Williamson, G. (2000) · The Journal of Nutrition · doi:10.1093/jn/130.8.2073s · Cited by 3,658 · see citing works
Self-citation
Prognostic Impact of Coronary Vasodilator Dysfunction on Adverse Long-Term Outcome of Coronary Heart Disease
Schächinger, V., Britten, M. B., & Zeiher, A. M. (2000) · Circulation · doi:10.1161/01.cir.101.16.1899 · Cited by 2,584 · see citing works
Flavonoid Intake and Long-term Risk of Coronary Heart Disease and Cancer in the Seven Countries Study
Hertog, M. G. L. (1995) · Archives of Internal Medicine · doi:10.1001/archinte.1995.00430040053006 · Cited by 2,225 · see citing works
The Relative Antioxidant Activities of Plant-Derived Polyphenolic Flavonoids
Rice-Evans, C. A., Miller, N. J., Bolwell, P., Bramley, P. M., & Pridham, J. B. (1995) · Free Radical Research · doi:10.3109/10715769509145649 · Cited by 2,163 · see citing works
Flavonoid intake and risk of chronic diseases
Knekt, P., Kumpulainen, J. T., Järvinen, R., Rissanen, H. A., Heliövaara, M., Reunanen, A., Hakulinen, T., & Aromaa, A. (2002) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/76.3.560 · Cited by 1,748 · see citing works
The Curry Spice Curcumin Reduces Oxidative Damage and Amyloid Pathology in an Alzheimer Transgenic Mouse
Lim, G. P., Chu, T., Yang, F., Beech, W., Frautschy, S. A., & Cole, G. M. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-21-08370.2001 · Cited by 1,530 · see citing works
Role of Free Radicals in the Neurodegenerative Diseases: Therapeutic Implications for Antioxidant Treatment
Halliwell, B. (2001) · Drugs & Aging · doi:10.2165/00002512-200118090-00004 · Cited by 1,502 · see citing works
Phenolics in Food and Nutraceuticals
Shahidi, F., & Naczk, M. (2003) · CRC Press eBooks · doi:10.1201/9780203508732 · Cited by 1,501 · see citing works
Soy intake and cancer risk: A review of the in vitro and in vivo data
Messina, M. J., Persky, V., Setchell, K. D. R., & Barnes, S. (1994) · Nutrition and Cancer · doi:10.1080/01635589409514310 · Cited by 1,315 · see citing works
High stored iron levels are associated with excess risk of myocardial infarction in eastern Finnish men
Salonen, J. T., Nyyssönen, K., Korpela, H., Tuomilehto, J., Seppänen, R., & Salonen, R. (1992) · Circulation · doi:10.1161/01.cir.86.3.803 · Cited by 1,284 · see citing works
Flavonoid intake and coronary mortality in Finland: a cohort study
Knekt, P., Jarvinen, R., Reunanen, A., & Maatela, J. (1996) · BMJ · doi:10.1136/bmj.312.7029.478 · Cited by 1,268 · see citing works
Risk Factors for Alzheimer's Disease: A Prospective Analysis from the Canadian Study of Health and Aging
Lindsay, J. (2002) · American Journal of Epidemiology · doi:10.1093/aje/kwf074 · Cited by 1,261 · see citing works
I<scp>NHIBITION OF</scp> C<scp>ARCINOGENESIS BY</scp> D<scp>IETARY</scp> P<scp>OLYPHENOLIC</scp> C<scp>OMPOUNDS</scp>
Yang, C. S., Landau, J. M., Huang, M.-T., & Newmark, H. L. (2001) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.21.1.381 · Cited by 1,260 · see citing works
Intake of potentially anticarcinogenic flavonoids and their determinants in adults in the Netherlands
Hertog, M. G. L., Hollman, P. C. H., Katan, M. B., & Kromhout, D. (1993) · Nutrition and Cancer · doi:10.1080/01635589309514267 · Cited by 1,216 · see citing works
Antidiabetic plants and their active constituents
Marles, R. J., & Farnsworth, N. R. (1995) · Phytomedicine · doi:10.1016/s0944-7113(11)80059-0 · Cited by 1,105 · see citing works
[241 Total antioxidant status in plasma and body fluids
Rice-Evans, C. A., & Miller, N. J. (1994) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(94)34095-1 · Cited by 991 · see citing works
Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation
Joseph, J. A., Shukitt-Hale, B., Denisova, N. A., Bielinski, D., Martin, A., McEwen, J. J., & Bickford, P. C. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-18-08114.1999 · Cited by 980 · see citing works
Inhibition of Carcinogenesis by Tea
Yang, C. S., Maliakal, P. P., & Meng, X. (2002) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.42.082101.154309 · Cited by 939 · see citing works
Principal Phenolic Phytochemicals in Selected California Wines and Their Antioxidant Activity in Inhibiting Oxidation of Human Low-Density Lipoproteins
Frankel, E. N., Waterhouse, A. L., & Teissèdre, P. (1995) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf00052a008 · Cited by 873 · see citing works
Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E–deficient mice
Aviram, M., Dornfeld, L., Rosenblat, M., Volkova, N., Kaplan, M., Coleman, R., Hayek, T., Presser, D., & Fuhrman, B. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.5.1062 · Cited by 866 · see citing works
Redox Regulation of NF-kappa B Activation
Flohé, L., Brigelius‐Flohé, R., Saliou, C., Traber, M. G., & Packer, L. (1997) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(96)00501-1 · Cited by 859 · see citing works
Health effects of vegetables and fruit: assessing mechanisms of action in human experimental studies
Lampe, J. W. (1999) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/70.3.475s · Cited by 786 · see citing works
Dietary Flavonoids and the Risk of Lung Cancer and Other Malignant Neoplasms
Knekt, P., rvinen, R. J., nen, R. S., vaara, M. H., Teppo, L., Pukkala, ., & Aromaa, A. (1997) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009257 · Cited by 770 · see citing works
Molecular origin of cancer: Catechol estrogen-3,4-quinones as endogenous tumor initiators
Cavalieri, E. L., Stack, D. E., Devanesan, P. D., Todorović, R., Dwivedy, I., Higginbotham, S. M., Johansson, S. L., Patil, K. D., Gross, M. L., Gooden, J. K., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.20.10937 · Cited by 728 · see citing works
Case-control study of phyto-oestrogens and breast cancer
Ingram, D., Sanders, K., Kolybaba, M. L., & Lopez, D. G. (1997) · The Lancet · doi:10.1016/s0140-6736(97)01339-1 · Cited by 722 · see citing works
Angiogenesis inhibited by drinking tea
Cao, Y., & Cao, R. (1999) · Nature · doi:10.1038/18793 · Cited by 691 · see citing works
Consumption of red wine with meals reduces the susceptibility of human plasma and low-density lipoprotein to lipid peroxidation
Fuhrman, B., Lavy, A., & Aviram, M. (1995) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/61.3.549 · Cited by 677 · see citing works
Intake of flavonoids and risk of dementia
Commenges, D., Scotet, V., Renaud, S., Jacqmin‐Gadda, H., Barberger‐Gateau, P., & Dartigues, J. (2000) · European Journal of Epidemiology · doi:10.1023/a:1007614613771 · Cited by 647 · see citing works
A general mechanism for microsomal activation of quinone anticancer agents to free radicals.
Bachur, N. R., Gordon, S. L., & Gee, M. V. (1978) · PubMed · Cited by 639 · see citing works
Phase I clinical trial of the flavonoid quercetin: pharmacokinetics and evidence for in vivo tyrosine kinase inhibition.
Ferry, D., de Smith, A. J., Malkhandi, J., Fyfe, D. W., DeTakats, P., Anderson, D., Baker, J., & Kerr, R. S. (1996) · PubMed · Cited by 630 · see citing works
Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo.
Hsieh, C., Santell, R., Haslam, S. Z., & Helferich, W. G. (1998) · PubMed · Cited by 609 · see citing works
Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis.
Talalay, P., Long, M. J., & Prochaska, H. J. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.21.8261 · Cited by 595 · see citing works
Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine
Johnston, K. L., Clifford, M. N., & Morgan, L. M. (2003) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/78.4.728 · Cited by 590 · see citing works
Quercetin is recovered in human plasma as conjugated derivatives which retain antioxidant properties
Manach, C., Morand, C., Crespy, V., Demigné, C., Texier, O., Regerat, F., & Rémésy, C. (1998) · FEBS Letters · doi:10.1016/s0014-5793(98)00367-6 · Cited by 586 · see citing works
Green tea polyphenol (–)‐epigallocatechin‐3‐gallate prevents N ‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine‐induced dopaminergic neurodegeneration
Levites, Y., Weinreb, O., Maor, G., Youdim, M. B. H., & Mandel, S. A. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00490.x · Cited by 567 · see citing works
Antioxidant and pro-oxidant actions of the plant phenolics quercetin, gossypol and myricetin
Laughton, M. J., Halliwell, B. B., Evans, P., Robin, J., & Hoult, S. (1989) · Biochemical Pharmacology · doi:10.1016/0006-2952(89)90442-5 · Cited by 559 · see citing works
Reduced Progression of Atherosclerosis in Apolipoprotein E–Deficient Mice Following Consumption of Red Wine, or Its Polyphenols Quercetin or Catechin, Is Associated With Reduced Susceptibility of LDL to Oxidation and Aggregation
Hayek, T., Fuhrman, B., Vaya, J., Rosenblat, M., Belinky, P. A., Coleman, R., Elis, A., & Aviram, M. (1997) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.17.11.2744 · Cited by 552 · see citing works
Short- and Long-Term Black Tea Consumption Reverses Endothelial Dysfunction in Patients With Coronary Artery Disease
Duffy, S. J., Keaney, J. F., HOLBROOK, M. M., Gokce, N., Swerdloff, P. L., Frei, B. B., & Vita, J. A. (2001) · Circulation · doi:10.1161/01.cir.104.2.151 · Cited by 552 · see citing works
Intake of Flavonoids and Lung Cancer
Marchand, L. L., Murphy, S. P., Hankin, J. H., Wilkens, L. R., & Kolonel, L. N. (2000) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/92.2.154 · Cited by 547 · see citing works
In vivo antioxidant effect of green and black tea in man.
Serafini, M., Ghiselli, A., & Ferro-Luzzi, A. (1996) · PubMed · Cited by 544 · see citing works
Isoflavone-rich soy protein isolate attenuates bone loss in the lumbar spine of perimenopausal women
Alekel, D. L., Germain, A. S., Peterson, C. T., Hanson, K. B., Stewart, J. W., & Toda, T. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/72.3.844 · Cited by 542 · see citing works
Wine consumption and dementia in the elderly: a prospective community study in the Bordeaux area.
Orgogozo, J. M., Dartigues, J. F., Lafont, S., Letenneur, L., Commenges, D., Salamon, R., Renaud, S., & Breteler, M. M. B. (1997) · PubMed · Cited by 525 · see citing works
Antioxidant flavonols and ischemic heart disease in a Welsh population of men: the Caerphilly Study
Hertog, M. G. L., Sweetnam, P. M., FEHILY, A. M., Elwood, P. C., & Kromhout, D. (1997) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/65.5.1489 · Cited by 511 · see citing works
Serum antioxidant capacity is increased by consumption of strawberries, spinach, red wine or vitamin C in elderly women
Cao, G., Russell, R. M., Lischner, N., & Prior, R. L. (1998) · The Journal of Nutrition · doi:10.1093/jn/128.12.2383 · Cited by 502 · see citing works
Inhibition of non-haem iron absorption in man by polyphenolic-containing beverages
Hurrell, R. F., Reddy, M., & Cook, J. D. (1999) · British Journal of Nutrition · doi:10.1017/s0007114599000537 · Cited by 490 · see citing works
Epigallocatechin Gallate, a Constituent of Green Tea, Represses Hepatic Glucose Production
Waltner-Law, M. E., Wang, X. L., Law, B. K., Hall, R. K., Nawano, M., & Granner, D. K. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m204672200 · Cited by 488 · see citing works
Comparative analysis of the effects of flavonoids on proliferation, cytotoxicity, and apoptosis in human colon cancer cell lines
Kuntz, S., Wenzel, U., & Daniel, H. (1999) · European Journal of Nutrition · doi:10.1007/s003940050054 · Cited by 484 · see citing works
The effects of organic acids, phytates and polyphenols on the absorption of iron from vegetables
Gillooly, M., Bothwell, T. H., Torrance, J. D., MacPhail, A. P., Derman, D. P., Bezwoda, W. R., Mills, W., Charlton, R. W., & Mayet, F. (1983) · British Journal of Nutrition · doi:10.1079/bjn19830042 · Cited by 480 · see citing works
Administration of Wine and Grape Juice Inhibits In Vivo Platelet Activity and Thrombosis in Stenosed Canine Coronary Arteries
Demrow, H. S., Slane, P. R., & Folts, J. D. (1995) · Circulation · doi:10.1161/01.cir.91.4.1182 · Cited by 452 · see citing works
Coffee consumption and risk of type 2 diabetes mellitus
van Dam, R. M., & Feskens, E. J. M. (2002) · The Lancet · doi:10.1016/s0140-6736(02)11436-x · Cited by 444 · see citing works
Alcohol-Free Red Wine Enhances Plasma Antioxidant Capacity in Humans
Serafini, M., Maiani, G., & Ferro-Luzzi, A. (1998) · Journal of Nutrition · doi:10.1093/jn/128.6.1003 · Cited by 442 · see citing works
A fluorescence-based method for measuring total plasma antioxidant capability
Ghiselli, A., Serafini, M., Maiani, G., Azzini, E., & Ferro-Luzzi, A. (1995) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(94)00102-p · Cited by 440 · see citing works
Dietary Flavonoid Intake and Risk of Cardiovascular Disease in Postmenopausal Women
Yochum, L., Kushi, L. H., Meyer, K., & Folsom, A. R. (1999) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009738 · Cited by 436 · see citing works
Long-Term Dietary Strawberry, Spinach, or Vitamin E Supplementation Retards the Onset of Age-Related Neuronal Signal-Transduction and Cognitive Behavioral Deficits
Joseph, J. A., Shukitt‐Hale, B., Denisova, N. A., Prior, R. L., Cao, G., Martín, A., Taglialatela, G., & Bickford, P. C. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-19-08047.1998 · Cited by 432 · see citing works
Effects of Genistein and Hormone-Replacement Therapy on Bone Loss in Early Postmenopausal Women: A Randomized Double-Blind Placebo-Controlled Study
Morabito, N., Crisafulli, A., Vergara, C., Gaudio, A., Lasco, A., Frisina, N., D’Anna, R., Corrado, F., Pizzoleo, M. A., Cincotta, M., et al. (2002) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2002.17.10.1904 · Cited by 432 · see citing works
Soy Isoflavones Improve Systemic Arterial Compliance but Not Plasma Lipids in Menopausal and Perimenopausal Women
Nestel, P. J., Yamashita, T., Sasahara, T., Pomeroy, S., Dart, A. M., Komesaroff, P. A., Owen, A. J., & Abbey, M. (1997) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.17.12.3392 · Cited by 432 · see citing works
Matrix metalloproteinase inhibition by green tea catechins
Demeule, M., Brossard, M., Pagé, M., Gingras, D., & Béliveau, R. (2000) · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · doi:10.1016/s0167-4838(00)00009-1 · Cited by 429 · see citing works
Antioxidant and prooxidant mechanisms in the regulation of redox(y)-sensitive transcription factors
Haddad, J. J. (2002) · Cellular Signalling · doi:10.1016/s0898-6568(02)00053-0 · Cited by 427 · see citing works
Whole‐grain intake and cancer: An expanded review and meta‐analysis
Jacobs, D. R., Marquart, L., Slavin, J., & Kushi, L. H. (1998) · Nutrition and Cancer · doi:10.1080/01635589809514647 · Cited by 423 · see citing works
Untitled work
(1989) · PubMed · Cited by 421 · see citing works
Green Tea Polyphenol Epigallocatechin-3-Gallate Differentially Modulates Nuclear Factor κB in Cancer Cells versus Normal Cells
Ahmad, N., Gupta, S., & Mukhtar, H. (2000) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.2000.1742 · Cited by 420 · see citing works
Tea Enhances Insulin Activity
Anderson, R. A., & Polansky, M. M. (2002) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf020514c · Cited by 366 · see citing works
Proanthocyanidin-rich extract from grape seeds attenuates the development of aortic atherosclerosis in cholesterol-fed rabbits
Yamakoshi, J., Kataoka, S., Koga, T., & Ariga, T. (1999) · Atherosclerosis · doi:10.1016/s0021-9150(98)00230-5 · Cited by 364 · see citing works
Protection against β‐amyloid peptide toxicity in vivo with long‐term administration of ferulic acid
Yan, J.-J., Cho, J., Kim, H., Kim, K., Jung, J., Huh, S., Suh, H., Kim, Y., & Song, D. (2001) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0704047 · Cited by 364 · see citing works
Epicatechin in Human Plasma: In Vivo Determination and Effect of Chocolate Consumption on Plasma Oxidation Status
Rein, D., LOTITO, S. B., Holt, R. R., Keen, C. L., Schmitz, H. H., & Fraga, C. G. (2000) · Journal of Nutrition · doi:10.1093/jn/130.8.2109s · Cited by 362 · see citing works
Does Tea Affect Cardiovascular Disease? A Meta-Analysis
Peters, U. (2001) · American Journal of Epidemiology · doi:10.1093/aje/154.6.495 · Cited by 362 · see citing works
The population mean predicts the number of deviant individuals.
Rose, G., & Day, S. (1990) · BMJ · doi:10.1136/bmj.301.6759.1031 · Cited by 360 · see citing works
Cocoa inhibits platelet activation and function
Rein, D., Paglieroni, T. G., Wun, T., Pearson, D. A., Schmitz, H. H., Gosselin, R. C., & Keen, C. L. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/72.1.30 · Cited by 359 · see citing works
Plasma and Hepatic Cholesterol and Hepatic Activities of 3-Hydroxy-3-methyl-glutaryl-CoA Reductase and Acyl CoA: Cholesterol Transferase Are Lower in Rats Fed Citrus Peel Extract or a Mixture of Citrus Bioflavonoids
Bok, S., Lee, S.-H., Park, Y.-B., Bae, K., Son, K., Jeong, T., & Choi, M. (1999) · Journal of Nutrition · doi:10.1093/jn/129.6.1182 · Cited by 357 · see citing works
Effect of red wine ingestion on the antioxidant capacity of serum
Whitehead, T. P., Robinson, D., Allaway, S. L., Syms, J., & Hale, A. (1995) · Clinical Chemistry · doi:10.1093/clinchem/41.1.32 · Cited by 354 · see citing works
Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate, and theaflavins.
Dong, Z., Ma, W., Huang, C., & Yang, C. S. (1997) · PubMed · Cited by 352 · see citing works
A single dose of tea with or without milk increases plasma antioxidant activity in humans
Leenen, R. C. A., Roodenburg, A. J. C., Tijburg, L. B. M., & Wiseman, S. A. (2000) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1600900 · Cited by 348 · see citing works
EXCRETION OF THE LIGNANS ENTEROLACTONE AND ENTERODIOL AND OF EQUOL IN OMNIVOROUS AND VEGETARIAN POSTMENOPAUSAL WOMEN AND IN WOMEN WITH BREAST CANCER
Adlercreutz, H., Heikkinen, R., Woods, M. N., Fotsis, T., Dwyer, J. T., Goldin, B. R., & Gorbach, S. L. (1982) · The Lancet · doi:10.1016/s0140-6736(82)91507-0 · Cited by 348 · see citing works
Catechin intake might explain the inverse relation between tea consumption and ischemic heart disease: the Zutphen Elderly Study
Arts, I. C. W., Hollman, P. C. H., Feskens, E. J. M., Bueno-de-Mesquita, H. B., & Kromhout, D. (2001) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/74.2.227 · Cited by 346 · see citing works
Vasorelaxing activity of resveratrol and quercetin in isolated rat aorta
Chen, C. K., & Pace-Asciak, C. R. (1996) · General Pharmacology The Vascular System · doi:10.1016/0306-3623(95)02001-2 · Cited by 343 · see citing works
The green tea polyphenol (−)-epigallocatechin gallate attenuates β-amyloid-induced neurotoxicity in cultured hippocampal neurons
Choi, Y.-T., Jung, C., Lee, S., Bae, J., Baek, W., Suh, M., Park, J., Park, C., & Suh, S. (2001) · Life Sciences · doi:10.1016/s0024-3205(01)01438-2 · Cited by 342 · see citing works
Anti-proliferative effect of resveratrol, a natural component of grapes and wine, on human colonic cancer cells
Schneider, Y., Vincent, F., Duranton, B., Badolo, L., Gossé, F., Bergmann, C., Seiler, N., & Raul, F. (2000) · Cancer Letters · doi:10.1016/s0304-3835(00)00511-5 · Cited by 341 · see citing works
Glutathione transferases catalyse the detoxication of oxidized metabolites (o-quinones) of catecholamines and may serve as an antioxidant system preventing degenerative cellular processes
Baez, S., Segura‐Aguilar, J., Widersten, M., Johansson, A.-S., & Mannervik, B. (1997) · Biochemical Journal · doi:10.1042/bj3240025 · Cited by 340 · see citing works
Genistein chemoprevention: timing and mechanisms of action in murine mammary and prostate.
Lamartiniere, C., Cotroneo, M. S., Fritz, W. A., Wang, J., Mentor-Marcel, R., & Elgavish, A. (2002) · Journal of NutriLife · doi:10.1093/jn/132.3.552s · Cited by 334 · see citing works
Untitled work
(1996) · PubMed · Cited by 323 · see citing works
Tea Catechins Prevent the Development of Atherosclerosis in Apoprotein E–Deficient Mice
Miura, Y., Chiba, T., Miura, S., Tomita, I., Koizumi, H., Umegaki, K., Hara, Y., Ikeda, M., & Tomita, T. (2001) · Journal of Nutrition · doi:10.1093/jn/131.1.27 · Cited by 321 · see citing works
Japanese Intake of Flavonoids and Isoflavonoids from Foods
Kimira, M., Arai, Y., Shimoi, K., & Watanabe, S. (1998) · Journal of Epidemiology · doi:10.2188/jea.8.168 · Cited by 317 · see citing works
Pomegranate Juice Supplementation to Atherosclerotic Mice Reduces Macrophage Lipid Peroxidation, Cellular Cholesterol Accumulation and Development of Atherosclerosis
Kaplan, M., Hayek, T., Raz, A., Coleman, R., Dornfeld, L., Vaya, J., & Aviram, M. (2001) · Journal of Nutrition · doi:10.1093/jn/131.8.2082 · Cited by 317 · see citing works
Intestinal Transport of Quercetin Glycosides in Rats Involves Both Deglycosylation and Interaction with the Hexose Transport Pathway
Gee, J. M., DuPont, M. S., Day, A. J., Plumb, G. W., Williamson, G., & Johnson, I. T. (2000) · Journal of Nutrition · doi:10.1093/jn/130.11.2765 · Cited by 313 · see citing works
Red wine and antioxidant activity in serum
Maxwell, S. R. J., Cruickshank, A., & Thorpe, G. H. G. (1994) · The Lancet · doi:10.1016/s0140-6736(94)92795-2 · Cited by 312 · see citing works
Food phenolics: Sources, chemistry, effects, applications
Griffiths, W. (1996) · Trends in Food Science & Technology · doi:10.1016/0924-2244(96)81226-x · Cited by 306 · see citing works
Soy isoflavones enhance coronary vascular reactivity in atherosclerotic female macaques
Honoré, E. K., Williams, J. K., Anthony, M. S., & Clarkson, T. B. (1997) · Fertility and Sterility · doi:10.1016/s0015-0282(97)81872-9 · Cited by 298 · see citing works
Effect of tea flavonoid supplementation on the susceptibility of low-density lipoprotein to oxidative modification
Ishikawa, T., Suzukawa, M., Ito, T., Yoshida, H., Ayaori, M., Nishiwaki, M., Yonemura, A., Hara, Y., & Nakamura, H. (1997) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/66.2.261 · Cited by 296 · see citing works
Tea drinking and bone mineral density in older women
Hegarty, V., May, H. M., & Khaw, K. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.4.1003 · Cited by 293 · see citing works
Attenuation of 6-hydroxydopamine (6-OHDA)-induced nuclear factor-kappaB (NF-κB) activation and cell death by tea extracts in neuronal cultures11Abbreviations: BT, Black Tea; EMSA, Electromobility Shift Assay; EGCG, (-)-Epigallocatechin-3-gallate; GT, Green Tea; NB SH-SY5Y cells, Human neuroblastoma SH-SY5Y cells; 6-OHDA, 6-hydroxydopamine; IL, Interleukin; LDH, Lactate Dehydrogenase; MPTP, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; NF-κB, nuclear factor-κB; OS, Oxidative Stress; PD, Parkinson’s Disease; ROS, Reactive Oxygen Species; SNPC, Substantia Nigra Pars Compacta; TBARS, thiobarbituric acid reactive substances.
Levites, Y., Youdim, M. B. H., Maor, G., & Mandel, S. (2002) · Biochemical Pharmacology · doi:10.1016/s0006-2952(01)00813-9 · Cited by 291 · see citing works
Mass Spectrometric Determination of Genistein Tissue Distribution in Diet-Exposed Sprague-Dawley Rats
Churchwell, M. I., Delclos, K. B., Chang, H. C.-W., Doerge, D. R., & Newbold, R. R. (2000) · Journal of Nutrition · doi:10.1093/jn/130.8.1963 · Cited by 284 · see citing works
Natural Dietary Polyphenolic Compounds Cause Endothelium-Dependent Vasorelaxation in Rat Thoracic Aorta
Andriambeloson, E., Magnier, C., Haan-Archipoff, G., Lobstein, A., Anton, R., Beretz, A., Stoclet, J., & Andriantsitohaina, R. (1998) · Journal of Nutrition · doi:10.1093/jn/128.12.2324 · Cited by 284 · see citing works
The Phytoestrogen Genistein Reduces Bone Loss in Short-Term Ovariectomized Rats
Fanti, P., Monier‐Faugere, M., Geng, Z., Schmidt, J., Morris, P. E., Cohen, D. A., & Malluche, H. H. (1998) · Osteoporosis International · doi:10.1007/s001980050065 · Cited by 283 · see citing works
Amount and type of alcohol and risk of dementia
Truelsen, T. C., Thudium, D., & Grønbæk, M. (2002) · Neurology · doi:10.1212/01.wnl.0000031421.50369.e7 · Cited by 283 · see citing works
Effect of fruit juice intake on urinary quercetin excretion and biomarkers of antioxidative status
Young, J. F., Nielsen, S. E., Haraldsdóttir, J., Daneshvar, B., Lauridsen, S. T., Knuthsen, P., Crozier, A., Sandström, B., & Dragsted, L. O. (1999) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/69.1.87 · Cited by 279 · see citing works
Daidzein Is More Efficient than Genistein in Preventing Ovariectomy-Induced Bone Loss in Rats
Barlet, J.-P., Picherit, C., Coxam, V., Bennetau‐Pelissero, C., Lebecque, P., Kati-Coulibaly, S., & Davicco, M.-J. (2000) · Journal of Nutrition · doi:10.1093/jn/130.7.1675 · Cited by 279 · see citing works
Physiological Concentrations of Dietary Genistein Dose-Dependently Stimulate Growth of Estrogen-Dependent Human Breast Cancer (MCF-7) Tumors Implanted in Athymic Nude Mice
Ju, Y. H., Allred, C. D., Allred, K. F., Karko, K. L., Doerge, D. R., & Helferich, W. G. (2001) · Journal of Nutrition · doi:10.1093/jn/131.11.2957 · Cited by 274 · see citing works
Grape Juice, But Not Orange Juice or Grapefruit Juice, Inhibits Human Platelet Aggregation
Keevil, J. G., Osman, H. E., Reed, J. D., & Folts, J. D. (2000) · Journal of Nutrition · doi:10.1093/jn/130.1.53 · Cited by 273 · see citing works
Daidzein and Genistein Glucuronides In Vitro Are Weakly Estrogenic and Activate Human Natural Killer Cells at Nutritionally Relevant Concentrations
Zhang, Y., Song, T. T., Cunnick, J. E., Murphy, P. A., & Hendrich, S. (1999) · Journal of Nutrition · doi:10.1093/jn/129.2.399 · Cited by 267 · see citing works
Inhibition of the mutagenicity of bay-region diol epoxides of polycyclic aromatic hydrocarbons by naturally occurring plant phenols: Exceptional activity of ellagic acid
Wood, A. W., Huang, M., Chang, R. L., Newmark, H. L., Lehr, R. E., Yagi, H., Sayer, J. M., Jerina, D. M., & Conney, A. H. (1982) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.79.18.5513 · Cited by 267 · see citing works
Anti-hyperglycemic effect of diacylated anthocyanin derived from Ipomoea batatas cultivar Ayamurasaki can be achieved through the alpha-glucosidase inhibitory action.
Matsui, T., Ebuchi, S., Kobayashi, M., Fukui, K., Sugita, K., Terahara, N., & Matsumoto, K. (2002) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf025913m · Cited by 267 · see citing works
Effects of the flavonoids quercetin and apigenin on hemostasis in healthy volunteers: results from an in vitro and a dietary supplement study
Janssen, K., Mensink, R. P., Cox, F., Harryvan, J., Hovenier, R., Hollman, P. C. H., & Katan, M. (1998) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/67.2.255 · Cited by 267 · see citing works
Effects of Cocoa Extracts on Endothelium-Dependent Relaxation
Karim, M., Hallam, K. M., & Kappagoda, C. T. (2000) · Journal of Nutrition · doi:10.1093/jn/130.8.2105s · Cited by 263 · see citing works
Flavonoid Inhibition of Sodium-dependent Vitamin C Transporter 1 (SVCT1) and Glucose Transporter Isoform 2 (GLUT2), Intestinal Transporters for Vitamin C and Glucose
Song, J., Kwon, O., Chen, S., Daruwala, R., Eck, P., Park, J. B., & Levine, M. N. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m110496200 · Cited by 262 · see citing works
Chlorogenic Acid and Hydroxynitrobenzaldehyde: New Inhibitors of Hepatic Glucose 6-Phosphatase
Arion, W. J., Canfield, W. K., Ramos, F. C., Schindler, P. W., Burger, H.-J., Hemmerle, H., Schubert, G., Below, P., & Herling, A. W. (1997) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1996.9874 · Cited by 259 · see citing works
Nutritional Aspects of Osteoporosis
(1998) · Springer eBooks · doi:10.1007/978-1-4612-2228-6 · Cited by 251 · see citing works
Effects of the phytochemicals, curcumin and quercetin, upon azoxymethane-induced colon cancer and 7, 12-dimethylbenz[ a ]anthracene-induced mammary cancer in rats
Pereira, M. A., Grubbs, C. J., Barnes, L., Li, H., Olson, G. R., Eto, I., Juliana, M. M., Whitaker, L. M., Kelloff, G. J., Steele, V. E., et al. (1996) · Carcinogenesis · doi:10.1093/carcin/17.6.1305 · Cited by 246 · see citing works
Phytoestrogen intake and prostate cancer: A case‐control study using a new database
Strom, S. S., Yamamura, Y., Duphorne, C. M., Spitz, M. R., Babaian, R. J., Pillow, P. C., & Hursting, S. D. (1999) · Nutrition and Cancer · doi:10.1080/01635589909514743 · Cited by 239 · see citing works
Catechol-O-methyltransferase-catalyzed rapid O-methylation of mutagenic flavonoids. Metabolic inactivation as a possible reason for their lack of carcinogenicity in vivo.
Zhu, B. T., Ezell, E. L., & Liehr, J. G. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)42348-9 · Cited by 237 · see citing works
Synergistic effects of (--)-epigallocatechin gallate with (--)-epicatechin, sulindac, or tamoxifen on cancer-preventive activity in the human lung cancer cell line PC-9.
Suganuma, M., Okabe, S., Kai, Y., Sueoka, N., Sueoka, E., & Fujiki, H. (1999) · PubMed · Cited by 236 · see citing works
Neurobehavioral aspects of antioxidants in aging
Cantuti‐Castelvetri, I., Shukitt‐Hale, B., & Joseph, J. A. (2000) · International Journal of Developmental Neuroscience · doi:10.1016/s0736-5748(00)00008-3 · Cited by 233 · see citing works
Phytoestrogens do not influence lipoprotein levels or endothelial function in healthy, postmenopausal women
Simons, L. A., von Konigsmark, M., Simons, J., & Celermajer, D. S. (2000) · The American Journal of Cardiology · doi:10.1016/s0002-9149(00)00759-1 · Cited by 230 · see citing works
Consumption of high doses of chlorogenic acid, present in coffee, or of black tea increases plasma total homocysteine concentrations in humans
Olthof, M. R., Hollman, P. C., Zock, P. L., & Katan, M. B. (2001) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/73.3.532 · Cited by 222 · cited 1× · see citing works
“[297] Olthof, M.”
Anti-apoptotic effect of quercetin: Intervention in the JNK- and ERK-mediated apoptotic pathways
Ishikawa, Y., & Kitamura, M. (2000) · Kidney International · doi:10.1046/j.1523-1755.2000.00265.x · Cited by 221 · see citing works
Inhibition of Thyroid Peroxidase by Dietary Flavonoids
Divi, R. L., & Doerge, D. R. (1996) · Chemical Research in Toxicology · doi:10.1021/tx950076m · Cited by 221 · see citing works
Individual and Combined Antioxidant Effects of Seven Phenolic Agents in Human Erythrocyte Membrane Ghosts and Phosphatidylcholine Liposome Systems: Importance of the Partition Coefficient
Liao, K.-L., & Yin, M. (2000) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf990946w · Cited by 216 · see citing works
Bone-sparing effect of soy protein in ovarian hormone–deficient rats is related to its isoflavone content
Arjmandi, B. H., Birnbaum, R. S., Goyal, N. V., Getlinger, M. J., Juma, S., Alekel, L. D., Hasler, C. M., Drum, M. L., Hollis, B. W., & Kukreja, S. C. (1998) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/68.6.1364s · Cited by 215 · see citing works
Supplementation with Isoflavonoid Phytoestrogens Does Not Alter Serum Lipid Concentrations: A Randomized Controlled Trial in Humans ,
Hodgson, J. M., Puddey, I. B., Beilin, L. J., Mori, T. A., & Croft, K. D. (1998) · Journal of Nutrition · doi:10.1093/jn/128.4.728 · Cited by 214 · see citing works
The effects of plant oestrogens on animal reproduction
SHUTT, D. (1976) · Endeavour · doi:10.1016/0160-9327(76)90004-1 · Cited by 208 · see citing works
Ingestion of red wine significantly increases plasma phenolic acid concentrations but does not acutely affect ex vivo lipoprotein oxidizability
Caccetta, R., Croft, K. D., Beilin, L. J., & Puddey, I. B. (2000) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/71.1.67 · Cited by 207 · see citing works
Caffeic acid as active principle from the fruit of Xanthium strumarium to lower plasma glucose in diabetic rats.
Hsu, F.-L., Chen, Y.-C., & Cheng, J.-T. (2000) · Planta Medica · doi:10.1055/s-2000-8561 · Cited by 207 · see citing works
Intake of specific carotenoids and flavonoids and the risk of gastric cancer in Spain
García-Closas, R., Gonzalez, C. A., Agudo, A., & Ríboli, E. (1999) · Cancer Causes & Control · doi:10.1023/a:1008867108960 · Cited by 205 · see citing works
Blocking telomerase by dietary polyphenols is a major mechanism for limiting the growth of human cancer cells in vitro and in vivo.
Naasani, I., Oh-hashi, F., Oh‐hara, T., Feng, W. Y., Johnston, J. S., Chan, K., & Tsuruo, T. (2003) · PubMed · Cited by 205 · see citing works
Inhibition of LDL oxidation by cocoa
Kondo, K. N., Hirano, R., Matsumoto, A., Igarashr, O., & Ltahura, H. (1996) · The Lancet · doi:10.1016/s0140-6736(05)65927-2 · Cited by 205 · see citing works
Detection of Weak Estrogenic Flavonoids Using a Recombinant Yeast Strain and a Modified MCF7 Cell Proliferation Assay
Breinholt, V. M., & Larsen, J. C. (1998) · Chemical Research in Toxicology · doi:10.1021/tx970170y · Cited by 203 · see citing works
Inhibition of oxidation of low-density lipoprotein with red wine
Kondo, K. N., Matsumoto, A., Kurata, H., Tanahashi, H., Kôda, H., Amachi, T., & Itakura, H. (1994) · The Lancet · doi:10.1016/s0140-6736(94)90656-4 · Cited by 202 · see citing works
Practice Guidelines for Tumor Marker Use in the Clinic
Sturgeon, C. M. (2002) · Clinical Chemistry · doi:10.1093/clinchem/48.8.1151 · Cited by 200 · see citing works
Tea Catechin Supplementation Increases Antioxidant Capacity and Prevents Phospholipid Hydroperoxidation in Plasma of Humans
Nakagawa, K., Ninomiya, M., Ōkubo, T., Aoi, N., Juneja, L. R., Kim, M., Yamanaka, K., & Miyazawa, T. (1999) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf981195l · Cited by 199 · see citing works
Deglucuronidation of a flavonoid, luteolin monoglucuronide, during inflammation.
Shimoi, K., Saka, N., Nozawa, R., Sato, M., Amano, I., Nakayama, T., & Kinae, N. (2001) · PubMed · Cited by 198 · see citing works
Population based cohort study of the association between alcohol intake and cancer of the upper digestive tract
Grønbæk, M., Becker, U., Johansen, D., Tønnesen, H., Jensen, G. B., & Sørensen, T. I. A. (1998) · BMJ · doi:10.1136/bmj.317.7162.844 · Cited by 197 · see citing works
Coffee and tea consumption in the Scottish Heart Health Study follow up: conflicting relations with coronary risk factors, coronary disease, and all cause mortality.
Woodward, M., & Tunstall-Pedoe, H. (1999) · Journal of Epidemiology and Community Health · doi:10.1136/jech.53.8.481 · Cited by 196 · see citing works
Rutin Inhibits Ovariectomy-Induced Osteopenia in Rats
Horcajada-Molteni, M.-N., Crespy, V., Coxam, V., Davicco, M.-J., Rémésy, C., & Barlet, J.-P. (2000) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2000.15.11.2251 · Cited by 195 · see citing works
Epicatechin and its in vivo metabolite, 3′-O-methyl epicatechin, protect human fibroblasts from oxidative-stress-induced cell death involving caspase-3 activation
Spencer, J. P. E., Schroeter, H., Kuhnle, G., Srai, S. K., Tyrrell, R. M., Hahn, U., & Rice-Evans, C. A. (2001) · Biochemical Journal · doi:10.1042/0264-6021:3540493 · Cited by 194 · see citing works
Urinary phytoestrogens and postmenopausal breast cancer risk.
den Tonkelaar, I., Keinan‐Boker, L., Veer, P. V. ’., Arts, C. J. M., Adlercreutz, H., Thijssen, J. H. H., & Peeters, P. H. M. (2001) · PubMed · Cited by 188 · see citing works
Consumption of green or black tea does not increase resistance of low-density lipoprotein to oxidation in humans
Hof, K. H. V. H., de Boer, H., Wiseman, S. A., Lien, N., Westrate, J. A., & Tijburg, L. B. M. (1997) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/66.5.1125 · Cited by 188 · see citing works
Dietary flavonols protect diabetic human lymphocytes against oxidative damage to DNA.
Lean, M. E. J., Noroozi, M., Kelly, I. R., Burns, J., Talwar, D., Sattar, N. A., & Crozier, A. (1999) · Diabetes · doi:10.2337/diabetes.48.1.176 · Cited by 186 · see citing works
Reduction of Blood Glucose Levels by Tea Catechin
Matsumoto, N., Ishigaki, F., Ishigaki, A., Iwashina, H., & Hara, Y. (1993) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.57.525 · Cited by 183 · see citing works
α-Glucosidase Inhibitory Action of Natural Acylated Anthocyanins. 2. α-Glucosidase Inhibition by Isolated Acylated Anthocyanins
Matsui, T., Ueda, T., Oki, T., Sugita, K., Terahara, N., & Matsumoto, K. (2001) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0012502 · Cited by 183 · see citing works
Anticarcinogenic Factors in Plant Foods: A New Class of Nutrients?
Johnson, I. T., Williamson, G., & Musk, S. R. R. (1994) · Nutrition Research Reviews · doi:10.1079/nrr19940011 · Cited by 181 · see citing works
Untitled work
(2000) · PubMed · Cited by 181 · see citing works
Plasma and Lipoprotein Levels of Tea Catechins Following Repeated Tea Consumption
Hof, K. H. V. H., Wiseman, S. A., Yang, C. S., & Tijburg, L. B. M. (1999) · Proceedings of The Society for Experimental Biology and Medicine · doi:10.1046/j.1525-1373.1999.d01-34.x · Cited by 178 · see citing works
Dietary inclusion of whole soy foods results in significant reductions in clinical risk factors for osteoporosis and cardiovascular disease in normal postmenopausal women
Scheiber, M. D., LIU, J. H., Subbiah, M. T. R., Rebar, R. W., & Setchell, K. D. R. (2001) · Menopause The Journal of The North American Menopause Society · doi:10.1097/00042192-200109000-00015 · Cited by 178 · see citing works
No Effect of Consumption of Green and Black Tea on Plasma Lipid and Antioxidant Levels and on LDL Oxidation in Smokers
Princen, H. M. G., van Duyvenvoorde, W., Buytenhek, R., Blonk, C., Tijburg, L. B. M., Langius, J. A. E., Meinders, A. E., & Pijl, H. (1998) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.18.5.833 · Cited by 178 · see citing works
Biological effects of hesperidin, a Citrus flavonoid. (note II): hypolipidemic activity on experimental hypercholesterolemia in rat.
Monforte, M. T., Trovato, A., Kirjavainen, S., Forestieri, A. M., Galati, E. M., & Curto, R. B. L. (1995) · PubMed · Cited by 178 · see citing works
Dietary catechins in relation to coronary heart disease death among postmenopausal women
Arts, I. C. W., Jacobs, D. R., Harnack, L., Gross, M. D., & Folsom, A. R. (2001) · Epidemiology · doi:10.1097/00001648-200111000-00015 · Cited by 177 · see citing works
Intake of Flavonols and Flavones and Risk of Coronary Heart Disease in Male Smokers
Hirvonen, T., Pietinen, P., Virtanen, M., Ovaskainen, M., Häkkinen, S., Albanes, D., & Virtamo, J. (2001) · Epidemiology · doi:10.1097/00001648-200101000-00011 · Cited by 176 · see citing works
Difference in Effective Dosage of Genistein on Bone and Uterus in Ovariectomized Mice
Ishimi, Y., Arai, N., Wang, X., Wu, J., Umegaki, K., Miyaura, C., Takeda, A., & Ikegami, S. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.3175 · Cited by 175 · see citing works
Beer increases plasma antioxidant capacity in humans
Ghiselli, A., Natella, F., Guidi, A., Montanari, L., Fantozzi, P., & Scaccini, C. (2000) · The Journal of Nutritional Biochemistry · doi:10.1016/s0955-2863(99)00077-7 · Cited by 175 · see citing works
Preventive Effects of the Plant Isoflavones, Daidzin and Genistin, on Bone Loss in Ovariectomized Rats Fed a Calcium-Deficient Diet.
ISHIDA, H., Uesugi, T., HIRAI, K., Toda, T., Nukaya, H., Yokotsuka, K., & Tsuji, K. (1998) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.21.62 · Cited by 174 · see citing works
Absorption and DNA protective effects of flavonoid glycosides from an onion meal
Boyle, S. P., Dobson, V. L., Duthie, S. J., Kyle, J. A. M., & Collins, A. R. (2000) · European Journal of Nutrition · doi:10.1007/s003940070014 · Cited by 173 · see citing works
Estrogenic and antiproliferative properties of glabridin from licorice in human breast cancer cells.
Tamir, S., Eizenberg, M., Sömjen, D., Stern, N., Shelach, R., Kaye, A. D., & Vaya, J. (2000) · PubMed · Cited by 173 · see citing works
Red wine consumption does not affect oxidizability of low-density lipoproteins in volunteers
de Rijke, Y., Demacker, P. N. M., Assen, N., Sloots, L., Katan, M., & Stalenhoef, A. F. H. (1996) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/63.3.329 · Cited by 173 · see citing works
Dietary catechins and cancer incidence among postmenopausal women: the Iowa Women's Health Study (United States)
Arts, I. C. W., Jacobs, D. R., Gross, M. D., Harnack, L., & Folsom, A. R. (2002) · Cancer Causes & Control · doi:10.1023/a:1015290131096 · Cited by 171 · see citing works
High-Performance Liquid Chromatography Coupled with Coulometric Array Detection of Electroactive Components in Fruits and Vegetables: Relationship to Oxygen Radical Absorbance Capacity
Guo, C., Cao, G., Sofic, E., & Prior, R. L. (1997) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf960786d · Cited by 171 · see citing works
Dietary Antioxidants and Lung Cancer Risk: A Case-Control Study in Uruguay
Stéfani, E. D., Boffetta, P., Deneo‐Pellegrini, H., Mendilaharsu, M., Carzoglio, J. C., Ronco, Á. L., & Olivera, L. (1999) · Nutrition and Cancer · doi:10.1207/s15327914nc340114 · Cited by 170 · see citing works
Quercetin metabolites inhibit copper ion‐induced lipid peroxidation in rat plasma1
da Silva, E. L., Piskuła, M. K., Yamamoto, N., Moon, J., & Terao, J. (1998) · FEBS Letters · doi:10.1016/s0014-5793(98)00709-1 · Cited by 167 · see citing works
Beneficial Effects of Soybean Isoflavone Supplementation on Bone Metabolism and Serum Lipids in Postmenopausal Japanese Women: A Four-Week Study
Uesugi, T., Fukui, Y., & Yamori, Y. (2002) · Journal of the American College of Nutrition · doi:10.1080/07315724.2002.10719200 · Cited by 166 · see citing works
Effects of Tea Polyphenols on the Invasion and Matrix Metalloproteinases Activities of Human Fibrosarcoma HT1080 Cells
Maeda‐Yamamoto, M., Kawahara, H., Tahara, N., Tsuji, K., Hara, Y., & Isemura, M. (1999) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9811525 · Cited by 165 · see citing works
Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin
Lin, J., Chen, Y., Huang, Y.-T., & Lin‐Shiau, S. (1997) · Journal of Cellular Biochemistry · doi:10.1002/(sici)1097-4644(1997)28/29+ · Cited by 163 · see citing works
A high‐fat diet induces and red wine counteracts endothelial dysfunction in human volunteers
Cuevas, A. M., Guasch, V., Castillo, O., Verónica Irribarra, P., Mizón, C., Martín, A. S., Strobel, P., Pérez, D., Germaín, A., & Leighton, F. (2000) · Lipids · doi:10.1007/bf02664763 · Cited by 159 · see citing works
Diet and risk of cancer of the upper aerodigestive tract—II. Nutrients
Stéfani, E. D., Ronco, Á. L., Mendilaharsu, M., & Deneo‐Pellegrini, H. (1999) · Oral Oncology · doi:10.1016/s1368-8375(98)00061-x · Cited by 158 · see citing works
Dietary Genistein Inactivates Rat Thyroid Peroxidase in Vivo without an Apparent Hypothyroid Effect
Chang, H. C.-W., & Doerge, D. R. (2000) · Toxicology and Applied Pharmacology · doi:10.1006/taap.2000.9019 · Cited by 154 · see citing works
Contrasting influences of glucuronidation and O-methylation of epicatechin on hydrogen peroxide-induced cell death in neurons and fibroblasts
Spencer, J. P. E., Schroeter, H., Crossthwaithe, A. J., Kuhnle, G., Williams, R. J., & Rice-Evans, C. A. (2001) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(01)00704-3 · Cited by 154 · see citing works
Platelet Rebound Effect of Alcohol Withdrawal and Wine Drinking in Rats
Ruf, J.-C., Berger, J.-L., & Renaud, S. C. (1995) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.15.1.140 · Cited by 153 · see citing works
Inhibition of human LDL lipid peroxidation by phenol-rich beverages and their impact on plasma total antioxidant capacity in humans
Serafini, M., Laranjinha, J. A. N., Almeida, L. M., & Maiani, G. (2000) · The Journal of Nutritional Biochemistry · doi:10.1016/s0955-2863(00)00124-8 · Cited by 152 · see citing works
Estrogenic and Antiestrogenic Activities of FlavonoidPhytochemicals Through Estrogen ReceptorBinding-Dependent and -Independent Mechanisms
Collins‐Burow, B. M., Burow, M. E., Duong, B. N., & McLachlan, J. A. (2000) · Nutrition and Cancer · doi:10.1207/s15327914nc382_13 · Cited by 151 · see citing works
Regeneration of α-Tocopherol in Human Low-Density Lipoprotein by Green Tea Catechin
Zhu, Q. Y., Huang, Y., Tsang, D., & Chen, Z. (1999) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9809941 · Cited by 151 · see citing works
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced NF-kappaB activation by tea polyphenols, (-)-epigallocatechin gallate and theaflavins
Nomura, M. (2000) · Carcinogenesis · doi:10.1093/carcin/21.10.1885 · Cited by 148 · see citing works
Extremely facile reaction between the ultimate carcinogen benzo[a]pyrene-7,8-diol 9,10-epoxide and ellagic acid
Sayer, J. M., Yagi, H., Wood, A. W., Conney, A. H., & Jerina, D. M. (1982) · Journal of the American Chemical Society · doi:10.1021/ja00384a081 · Cited by 147 · see citing works
Grape Juice but Not Orange or Grapefruit Juice Inhibits Platelet Activity in Dogs and Monkeys (Macaca fasciularis)
Osman, H. E., Maalej, N. M., Shanmuganayagam, D., & Folts, J. D. (1998) · Journal of Nutrition · doi:10.1093/jn/128.12.2307 · Cited by 145 · see citing works
Flavonol and flavone intake and the risk of cancer in male smokers (Finland)
Hirvonen, T., Virtamo, J. R. K., Korhonen, P. A., Albanes, D., & Pietinen, P. (2001) · Cancer Causes & Control · doi:10.1023/a:1012232008016 · Cited by 144 · see citing works
Polyphenols As Inhibitors of Carcinogenesis
Yang, C. S., Lee, M. J., Chen, L., & Yang, G. (1997) · Environmental Health Perspectives · doi:10.1289/ehp.97105s4971 · Cited by 144 · see citing works
Urinary tea polyphenols in relation to gastric and esophageal cancers: a prospective study of men in Shanghai, China
Sun, C. (2002) · Carcinogenesis · doi:10.1093/carcin/23.9.1497 · Cited by 143 · see citing works
Plasma polyphenols and antioxidants, oxidative DNA damage and endothelial function in a diet and wine intervention study in humans.
Leighton, F., Cuevas, A. M., Guasch, V., Pérez, D. D., Strobel, P., Martín, A. S., Urzua, U., Diez, M. S., Foncea, R. E., Castillo, O., et al. (1999) · PubMed · Cited by 139 · see citing works
The effects of phytoestrogens on bone
Anderson, J. J. B., & Garner, S. C. (1997) · Nutrition Research · doi:10.1016/s0271-5317(97)00156-5 · Cited by 139 · see citing works
Antithyroid and Goitrogenic Effects of Millet: Role of C-Glycosylflavones*
Gaitán, E., LINDSAY, R. H., REICHERT, R. D., Ingbar, S. H., Cooksey, R. C., Legan, J. S., Meydrech, E. F., HILL, J., & Kubota, K. (1989) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-68-4-707 · Cited by 139 · see citing works
Genistein Is a Natural Inhibitor of Hexose and Dehydroascorbic Acid Transport through the Glucose Transporter, GLUT1
Vera, J. C., Reyes, A. M., Cárcamo, J. G., Velásquez, F. V., Rivas, C. I., Zhang, R. H., Strobel, P., Iribarren, R., Scher, H. I., Slebe, J. C., et al. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.15.8719 · Cited by 138 · see citing works
Free Radicals in Biology: Sources, Reactivities, and Roles in the Etiology of Human Diseases
Kehrer, J. P., & Smith, C. V. (1994) · Elsevier eBooks · doi:10.1016/b978-0-08-057168-3.50008-4 · Cited by 137 · see citing works
Potential Adverse Effects of Phytoestrogens
Whitten, P. L., Lewis, C., Russell, E., & Naftolin, F. N. (1995) · Journal of Nutrition · doi:10.1093/jn/125.suppl_3.771s · Cited by 137 · see citing works
(-)-Epigallocatechin-3-gallate inhibition of ultraviolet B-induced AP-1 activity
Barthelman, M. (1998) · Carcinogenesis · doi:10.1093/carcin/19.12.2201 · Cited by 134 · see citing works
Modulation of haemostatic function and prevention of experimental thrombosis by red wine in rats: a role for increased nitric oxide production
Wollny, T., Aiello, L., Tommaso, D. D., Bellavia, V., Rotilio, D., Donati, M. B., de Gaetano, G., & Iacoviello, L. (1999) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0702586 · Cited by 132 · see citing works
Quercetin selectively inhibits insulin receptor function in vitro and the bioresponses of insulin and insulinomimetic agents in rat adipocytes
Shisheva, A., & Shechter, Y. (1992) · Biochemistry · doi:10.1021/bi00149a041 · Cited by 132 · see citing works
Amelioration of renal lesions associated with diabetes by dietary curcumin in streptozotocin diabetic rats
Babu, P. S., & Srinivasan, K. (1998) · Molecular and Cellular Biochemistry · doi:10.1023/a:1006821828706 · Cited by 131 · see citing works
Potential adverse effects of phytoestrogens.
Whitten, P. L., Lewis, C., Russell, E., et al. (1995) · PubMed · doi:10.1093/jn/125.3_suppl.771s · Cited by 130 · see citing works
Inactivation of thyroid peroxidase by soy isoflavones, in vitro and in vivo
Doerge, D. R., & Chang, H. C. (2002) · Journal of Chromatography B · doi:10.1016/s1570-0232(02)00214-3 · Cited by 129 · see citing works
Cholesterol-Lowering Activity of Naringenin via Inhibition of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase and Acyl Coenzyme A:Cholesterol Acyltransferase in Rats
Lee, S., Park, Y. B., Bae, K., Bok, S., Kwon, Y., Lee, E. S., & Choi, M. (1999) · Annals of Nutrition and Metabolism · doi:10.1159/000012783 · Cited by 128 · see citing works
Origin, genetic diversity, and genome structure of the domestic dog
Wayne, R. K., & Ostrander, E. A. (1999) · BioEssays · doi:10.1002/(sici)1521-1878(199903)21:3 · Cited by 128 · see citing works
Prostate cancer chemoprevention by green tea: in vitro and in vivo inhibition of testosterone-mediated induction of ornithine decarboxylase.
Gupta, S., Ahmad, N., Mohan, R. R., Husain, M. M., & Mukhtar, H. (1999) · PubMed · Cited by 125 · see citing works
Binding of flavonoids to plasma proteins
Dangles, O., Dufour, C., Manach, C., Morand, C., & Rémésy, C. (2001) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(01)35254-0 · Cited by 123 · see citing works
Dietary Grape Seed Tannins Affect Lipoproteins, Lipoprotein Lipases and Tissue Lipids in Rats Fed Hypercholesterolemic Diets , ,
Tebib, K., Besançon, P., & Rouanet, J. (1994) · Journal of Nutrition · doi:10.1093/jn/124.12.2451 · Cited by 122 · see citing works
[34] Determination of phospholipid hydroperoxides using luminol chemiluminescence—high-performance liquid chromatography
Miyazawa, T., Fujimoto, K., Suzuki, T., & Yasuda, K. (1994) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(94)33037-9 · Cited by 121 · see citing works
Efficacy of a soy rich diet in preventing postmenopausal osteoporosis: the Menfis randomized trial
Chiechi, L. M., Secreto, G., D’Amore, S., Fanelli, M., Venturelli, E., Cantatore, F. P., Valerio, T., Laselva, G., & Loizzi, P. (2002) · Maturitas · doi:10.1016/s0378-5122(02)00158-5 · Cited by 120 · see citing works
4-Hydroxybenzoic acid: a hypoglycemic constituent of aqueous extract of Pandanus odorus root
Peungvicha, P., Temsiririrkkul, R., PRASAIN, J. K., Tezuka, Y., Kadota, S., Thirawarapan, S. S., & Watanabe, H. (1998) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(98)00061-0 · Cited by 118 · see citing works

Flagged first, then by citations

2 of the 306 references couldn’t be matched to a known paper.

Sorted by citations

Plant Polyphenols as Dietary Antioxidants in Human Health and Disease
Pandey, K. B., & Rizvi, S. I. (2009) · Oxidative Medicine and Cellular Longevity · doi:10.4161/oxim.2.5.9498 · Cited by 4,727 · see citing works
Plant Phenolics: Extraction, Analysis and Their Antioxidant and Anticancer Properties
Dai, J., & Mumper, R. J. (2010) · Molecules · doi:10.3390/molecules15107313 · Cited by 4,541 · see citing works
Plant Polyphenols: Chemical Properties, Biological Activities, and Synthesis
Quideau, S., Deffieux, D., Douat, C., & Pouységu, L. (2011) · Angewandte Chemie International Edition · doi:10.1002/anie.201000044 · Cited by 2,753 · see citing works
The Immunomodulatory and Anti-Inflammatory Role of Polyphenols
Yahfoufi, N., Alsadi, N., Jambi, M., & Matar, C. (2018) · Nutrients · doi:10.3390/nu10111618 · Cited by 1,737 · see citing works
Phenolic acids: Natural versatile molecules with promising therapeutic applications
Kumar, N., & Goel, N. (2019) · Biotechnology Reports · doi:10.1016/j.btre.2019.e00370 · Cited by 1,755 · see citing works
Encapsulation of polyphenols – a review
Fang, Z., & Bhandari, B. (2010) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2010.08.003 · Cited by 1,570 · see citing works
Dietary polyphenols, oxidative stress and antioxidant and anti-inflammatory effects
Zhang, H., & Tsao, R. (2016) · Current Opinion in Food Science · doi:10.1016/j.cofs.2016.02.002 · Cited by 1,519 · see citing works
A critical review of methods for characterisation of polyphenolic compounds in fruits and vegetables
Ignat, I., Volf, I., & Popa, V. (2010) · Food Chemistry · doi:10.1016/j.foodchem.2010.12.026 · Cited by 1,474 · see citing works
Phenol-Explorer: an online comprehensive database on polyphenol contents in foods
Neveu, V., Pérez‐Jiménez, J., Vos, F., Crespy, V., Chaffaut, L. D., Mennen, L. I., Knox, C., Eisner, R., Cruz, J., Wishart, D. S., et al. (2010) · Database · doi:10.1093/database/bap024 · Cited by 1,442 · see citing works
Techniques for Analysis of Plant Phenolic Compounds
Khoddami, A., Wilkes, M. A., & Roberts, T. H. (2013) · Molecules · doi:10.3390/molecules18022328 · Cited by 1,335 · see citing works
Impact of Dietary Polyphenols on Carbohydrate Metabolism
Hanhineva, K., Törrönen, R., Bondia‐Pons, I., Pekkinen, J., Kolehmainen, M., Mykkänen, H. M., & Poutanen, K. S. (2010) · International Journal of Molecular Sciences · doi:10.3390/ijms11041365 · Cited by 1,167 · see citing works
Millet Grains: Nutritional Quality, Processing, and Potential Health Benefits
Saleh, A. S. M., Zhang, Q. R., Chen, J., & Shen, Q. (2013) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12012 · Cited by 1,114 · see citing works
Dietary Polyphenols and Their Role in Oxidative Stress-Induced Human Diseases: Insights Into Protective Effects, Antioxidant Potentials and Mechanism(s) of Action
Rudrapal, M., Khairnar, S. J., Khan, J., Dukhyil, A. B., Ansari, M. A., Alomary, M. N., Alshabrmi, F. M., Palai, S., Deb, P. K., & Devi, R. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.806470 · Cited by 1,103 · see citing works
Polyphenols: Extraction Methods, Antioxidative Action, Bioavailability and Anticarcinogenic Effects
Brglez Mojzer, E., Knez Hrnčič, M., Škerget, M., Knez, Ž., & Bren, U. (2016) · Molecules · doi:10.3390/molecules21070901 · Cited by 1,096 · see citing works
(–)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans
Schroeter, H., Heiss, C., Balzer, J., Kleinbongard, P., Keen, C. L., Hollenberg, N. K., Sies, H., Kwik-Uribe, C., Schmitz, H. H., & Kelm, M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510168103 · Cited by 1,052 · see citing works
A High Quality Draft Consensus Sequence of the Genome of a Heterozygous Grapevine Variety
Velasco, R., Zharkikh, A., Troggio, M., Cartwright, D., Cestaro, A., Pruss, D., Pindo, M., Fitzgerald, L. M., Vezzulli, S., Reid, J., et al. (2007) · PLoS ONE · doi:10.1371/journal.pone.0001326 · Cited by 1,046 · see citing works
Resources and Biological Activities of Natural Polyphenols
Li, A., Li, S., Zhang, Y., Xu, X., Chen, Y., & Li, H. (2014) · Nutrients · doi:10.3390/nu6126020 · Cited by 885 · see citing works
Phenol-Explorer 3.0: a major update of the Phenol-Explorer database to incorporate data on the effects of food processing on polyphenol content
Rothwell, J. A., Pérez‐Jiménez, J., Neveu, V., Medina‐Remón, A., M'hiri, N., Garcia-Lobato, P., Manach, C., Knox, C., Eisner, R., Wishart, D. S., et al. (2013) · Database · doi:10.1093/database/bat070 · Cited by 884 · see citing works
Identification and quantification of phenolic compounds from pomegranate (Punica granatum L.) peel, mesocarp, aril and differently produced juices by HPLC-DAD–ESI/MSn
Fischer, U. A., Carle, R., & Kammerer, D. R. (2011) · Food Chemistry · doi:10.1016/j.foodchem.2010.12.156 · Cited by 876 · see citing works
Concept, mechanism, and applications of phenolic antioxidants in foods
Zeb, A. (2020) · Journal of Food Biochemistry · doi:10.1111/jfbc.13394 · Cited by 909 · see citing works
Role of Phenolic Compounds in Human Disease: Current Knowledge and Future Prospects
Rahman, M. M., Rahaman, M. S., Islam, M. R., Rahman, F., Mithi, F. M., Alqahtani, T., Almikhlafi, M. A., Alghamdi, S. Q., Alruwaili, A. S., Hossain, M. S., et al. (2021) · Molecules · doi:10.3390/molecules27010233 · Cited by 900 · see citing works
“Polyphenols are secondary plant metabolites that play a vital role in protecting plants from UV radiation and disease attacks [1].”
Background
The Reciprocal Interactions between Polyphenols and Gut Microbiota and Effects on Bioaccessibility
Özdal, T., Sela, D. A., Xiao, J., Boyacıoğlu, D., Chen, F., & Çapanoğlu, E. (2016) · Nutrients · doi:10.3390/nu8020078 · Cited by 812 · see citing works
Identification of the 100 richest dietary sources of polyphenols: an application of the Phenol-Explorer database
Pérez‐Jiménez, J., Neveu, V., Vos, F., & Scalbert, A. (2010) · European Journal of Clinical Nutrition · doi:10.1038/ejcn.2010.221 · Cited by 798 · see citing works
Polyphenols, dietary sources and bioavailability.
D’Archivio, M., Filesi, C., Benedetto, R. D., Gargiulo, R., Giovannini, C., & Masella, R. (2007) · PubMed · Cited by 791 · see citing works
Flavan‐3‐ols: Nature, occurrence and biological activity
Aron, P. M., & Kennedy, J. A. (2007) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200700137 · Cited by 770 · see citing works
Pomegranate and its many functional components as related to human health: a review
Viuda‐Martos, M., Fernández‐López, J., & Pérez‐Álvarez, J. A. (2010) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/j.1541-4337.2010.00131.x · Cited by 768 · see citing works
Oxidative stress in bone remodeling: role of antioxidants
Domazetovic, V (2017) · Clinical Cases in Mineral and Bone Metabolism · doi:10.11138/ccmbm/2017.14.1.209 · Cited by 758 · see citing works
Polyphenol Composition and in Vitro Antioxidant Activity of Amaranth, Quinoa Buckwheat and Wheat as Affected by Sprouting and Baking
Alvarez-Jubete, L., Wijngaard, H., Arendt, E. K., & Gallagher, E. (2010) · Food Chemistry · doi:10.1016/j.foodchem.2009.07.032 · Cited by 736 · see citing works
Flavonoid Composition of Citrus Juices
Gattuso, G., Barreca, D., Gargiulli, C., Leuzzi, U., & Caristi, C. (2007) · Molecules · doi:10.3390/12081641 · Cited by 702 · see citing works
Nutritive value of pseudocereals and their increasing use as functional gluten-free ingredients
Alvarez-Jubete, L., Arendt, E. K., & Gallagher, E. (2010) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2009.10.014 · Cited by 688 · see citing works
Polyphenols and prevention of cardiovascular diseases
Manach, C., Mazur, A., & Scalbert, A. (2005) · Current Opinion in Lipidology · doi:10.1097/00041433-200502000-00013 · Cited by 680 · see citing works
Food Components and Dietary Habits: Keys for a Healthy Gut Microbiota Composition
Rinninella, E., Cintoni, M., Raoul, P. C., Lopetuso, L. R., Scaldaferri, F., Pulcini, G., Miggiano, G. A. D., Gasbarrini, A., & Mele, M. C. (2019) · Nutrients · doi:10.3390/nu11102393 · Cited by 678 · see citing works
“As these compounds are known to be implicated in preventing CVD [117], diabetes, obesity, and many other diseases [118], they currently represent a topic of growing interest for the scientific community.”
Background
Polyphenol‐Containing Nanoparticles: Synthesis, Properties, and Therapeutic Delivery
Guo, Y., Sun, Q., Wu, F., Dai, Y., & Chen, X. S. (2021) · Advanced Materials · doi:10.1002/adma.202007356 · Cited by 658 · see citing works
Bioactive Compounds and Health-Promoting Properties of Berry Fruits: A Review
Szajdek, A., & Borowska, E. (2008) · Plant foods for human nutrition · doi:10.1007/s11130-008-0097-5 · Cited by 643 · see citing works
Fruits and vegetables, as a source of nutritional compounds and phytochemicals: Changes in bioactive compounds during lactic fermentation
Septembre‐Malaterre, A., Remize, F., & Poucheret, P. (2017) · Food Research International · doi:10.1016/j.foodres.2017.09.031 · Cited by 633 · see citing works
Rutin: A review on extraction, identification and purification methods, biological activities and approaches to enhance its bioavailability
Gullón, B., Lu-Chau, T. A., Moreira, M. T., Lema, J. M., & Eibes, G. (2017) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2017.07.008 · Cited by 611 · see citing works
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
Kell, D. B. (2009) · BMC Medical Genomics · doi:10.1186/1755-8794-2-2 · Cited by 554 · see citing works
Potential and challenges of tannins as an alternative to in-feed antibiotics for farm animal production
Huang, Q., Liu, X., Zhao, G., Hu, T., & Wang, Y. (2018) · Animal nutrition · doi:10.1016/j.aninu.2017.09.004 · Cited by 555 · see citing works
Polyphenols and Glycemic Control
Kim, Y., Keogh, J. B., & Clifton, P. M. (2016) · Nutrients · doi:10.3390/nu8010017 · Cited by 557 · see citing works
Flavonoids as natural phenolic compounds and their role in therapeutics: an overview
Mutha, R. E., Tatiya, A. U., & Surana, S. J. (2021) · Future Journal of Pharmaceutical Sciences · doi:10.1186/s43094-020-00161-8 · Cited by 626 · see citing works
“Overexpression of phase II enzymes is associated with the toxicity of polyphenols [2].”
BackgroundInfluential
Metabolic fate of polyphenols in the human superorganism
van Duynhoven, J., Vaughan, E. E., Jacobs, D. M., A. Kemperman, R., van Velzen, E. J. J., Gross, G., Roger, L. C., Possemiers, S., Smilde, A. K., Doré, J., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1000098107 · Cited by 540 · see citing works
The effects of ultrasound assisted extraction on yield, antioxidant, anticancer and antimicrobial activity of polyphenol extracts: A review
Dzah, C. S., Duan, Y., Zhang, H., Wen, C., Zhang, J., Chen, G., & Ma, H. (2020) · Food Bioscience · doi:10.1016/j.fbio.2020.100547 · Cited by 544 · see citing works
Anticancer Efficacy of Polyphenols and Their Combinations
Niedzwiecki, A., Roomi, M. W., Kalinovsky, T., & Rath, M. (2016) · Nutrients · doi:10.3390/nu8090552 · Cited by 541 · see citing works
Protein Oxidation in Processed Meat: Mechanisms and Potential Implications on Human Health
Soladoye, O. P., Juárez, M. L., Aalhus, J. L., Shand, P. J., & Estévez, M. (2015) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12127 · Cited by 539 · see citing works
The food metabolome: a window over dietary exposure
Scalbert, A., Brennan, L., Manach, C., Andres-Lacueva, C., Dragsted, L. O., Draper, J., Rappaport, S. M., van der Hooft, J. J., & Wishart, D. S. (2014) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.113.076133 · Cited by 519 · see citing works
Foeniculum vulgare Mill: A Review of Its Botany, Phytochemistry, Pharmacology, Contemporary Application, and Toxicology
Badgujar, S. B., Patel, V. V., & Bandivdekar, A. H. (2014) · BioMed Research International · doi:10.1155/2014/842674 · Cited by 508 · see citing works
Synthesis and Biological Application of Polylactic Acid
Li, G., Zhao, M., Xu, F., Yang, B., Li, X., Meng, X., Teng, L., Sun, F., & Li, Y. (2020) · Molecules · doi:10.3390/molecules25215023 · Cited by 492 · see citing works
Oxidative stress in bone remodelling and disease
Wauquier, F., Léotoing, L., Coxam, V., Guicheux, J., & Wittrant, Y. (2009) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2009.08.004 · Cited by 489 · see citing works
Polyphenols and their benefits: A review
Rasouli, H., Farzaei, M. H., & Khodarahmi‬, R. (2017) · International Journal of Food Properties · doi:10.1080/10942912.2017.1354017 · Cited by 490 · see citing works
Effect of solvent, time and temperature on the extraction of phenolic compounds and antioxidant capacity of peach (Prunus persica L.) fruit
Mokrani, A., & Madani, K. (2016) · Separation and Purification Technology · doi:10.1016/j.seppur.2016.01.043 · Cited by 474 · see citing works
Antioxidant capacity, phenolic content and vitamin C in pulp, peel and seed from 24 exotic fruits from Colombia
Contreras‐Calderón, J., CALDERÓN-JAIMES, L. S., Guerra-Hernández, E. J., & García‐Villanova, B. (2010) · Food Research International · doi:10.1016/j.foodres.2010.11.003 · Cited by 453 · see citing works
Nutrition, physical activity, and cardiovascular disease: An update
IGNARRO, L., Balestrieri, M. L., & Claudio Napoli, A. (2006) · Cardiovascular Research · doi:10.1016/j.cardiores.2006.06.030 · Cited by 443 · see citing works
Oxidative stress and human diseases: Origin, link, measurement, mechanisms, and biomarkers
Giustarini, D., Dalle‐Donne, I., Tsikas, D., & Rossi, R. (2009) · Critical Reviews in Clinical Laboratory Sciences · doi:10.3109/10408360903142326 · Cited by 443 · see citing works
Dietary intake of 337 polyphenols in French adults
Pérez‐Jiménez, J., Fezeu, L., Touvier, M., Arnault, N., Manach, C., Herçberg, S., Galan, P., & Scalbert, A. (2011) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.007096 · Cited by 425 · see citing works
Flavonoids and other phenolic compounds in Andean indigenous grains: Quinoa (Chenopodium quinoa), kañiwa (Chenopodium pallidicaule) and kiwicha (Amaranthus caudatus)
Repo‐Carrasco‐Valencia, R., Hellström, J., Pihlava, J., & Mattila, P. H. (2009) · Food Chemistry · doi:10.1016/j.foodchem.2009.09.087 · Cited by 405 · see citing works
Antioxidant and antiacetylcholinesterase activities of five plants used as Portuguese food spices
Mata, A. T., Proença, C. S., Ferreira, A. R., Serralheiro, M. L., Nogueira, J. M. F., & Araújo, M. E. (2006) · Food Chemistry · doi:10.1016/j.foodchem.2006.09.017 · Cited by 401 · see citing works
Food‐Grade Covalent Complexes and Their Application as Nutraceutical Delivery Systems: A Review
Liu, F., Ma, C., Gao, Y., & McClements, D. J. (2016) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12229 · Cited by 401 · see citing works
Clinical effects of curcumin in enhancing cancer therapy: A systematic review
Mansouri, K., Rasoulpoor, S., Daneshkhah, A., Abolfathi, S., Salari, N., Mohammadi, M., Rasoulpoor, S., & Shabani, S. (2020) · BMC Cancer · doi:10.1186/s12885-020-07256-8 · Cited by 392 · see citing works
RETRACTED: Updated Knowledge about Polyphenols: Functions, Bioavailability, Metabolism, and Health
Landete, J. M. (2012) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2010.513779 · Cited by 396 · see citing works
Retracted
Food processing strategies to enhance phenolic compounds bioaccessibility and bioavailability in plant-based foods
Ribas, A. I., Martín‐Belloso, O., Soliva‐Fortuny, R., & Elez‐Martínez, P. (2017) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2017.1331200 · Cited by 374 · see citing works
“In this sense, some authors have related these biological activities with reduced risk of cancer and cardiovascular diseases (Scalbert et al., 2005).”
Background
Polyphenols, intracellular signalling and inflammation.
Santangelo, C., Varı́, R., Scazzocchio, B., Benedetto, R. D., Filesi, C., & Masella, R. (2007) · PubMed · Cited by 369 · see citing works
Antioxidant Activity of Phenolic Compounds: FromIn VitroResults toIn VivoEvidence
Fernández‐Pachón, M., Villaño, D., Troncoso, A. M., & García-Parrilla, M. C. (2008) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408390701761845 · Cited by 365 · see citing works
Nutritional Quality of Legumes, and Their Role in Cardiometabolic Risk Prevention: A Review
Bouchenak, M., & Lamri‐Senhadji, M. (2013) · Journal of Medicinal Food · doi:10.1089/jmf.2011.0238 · Cited by 362 · see citing works
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson’s, Huntington’s, Alzheimer’s, prions, bactericides, chemical toxicology and others as examples
Kell, D. B. (2010) · Archives of Toxicology · doi:10.1007/s00204-010-0577-x · Cited by 361 · see citing works
Review of Finger millet (Eleusine coracana (L.) Gaertn): A power house of health benefiting nutrients
Chandra, D., Chandra, S., Pallavi, P., & Sharma, A. K. (2016) · Food Science and Human Wellness · doi:10.1016/j.fshw.2016.05.004 · Cited by 350 · see citing works
Grape pomace as a source of phenolic compounds and diverse bioactive properties
Peixoto, C. M., Días, M. I., Alves, M. J., Calhelha, R. C., Barros, L., Pinho, S. P., & Ferreira, I. C. F. R. (2018) · Food Chemistry · doi:10.1016/j.foodchem.2018.01.163 · Cited by 348 · see citing works
Phenolic Compounds in the Potato and Its Byproducts: An Overview
Akyol, H., Riciputi, Y., Çapanoğlu, E., Caboni, M. F., & Verardo, V. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17060835 · Cited by 356 · see citing works
Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines
Araújo, J. R., Gonçalves, P., & Martel, F. (2011) · Nutrition Research · doi:10.1016/j.nutres.2011.01.006 · Cited by 340 · see citing works
Systematic Analysis of the Content of 502 Polyphenols in 452 Foods and Beverages: An Application of the Phenol-Explorer Database
Pérez‐Jiménez, J., Neveu, V., Vos, F., & Scalbert, A. (2010) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf100128b · Cited by 340 · see citing works
Bioaccessibility and antioxidant potential of millet grain phenolics as affected by simulated in vitro digestion and microbial fermentation
Chandrasekara, A., & Shahidi, F. (2012) · Journal of Functional Foods · doi:10.1016/j.jff.2011.11.001 · Cited by 334 · see citing works
Total Phenolic, Flavonoid Contents, and Antioxidant Activities of Fruit, Seed, and Bark Extracts of Zanthoxylum armatum DC
Phuyal, N., Jha, P. K., Raturi, P. P., & Rajbhandary, S. (2020) · The Scientific World JOURNAL · doi:10.1155/2020/8780704 · Cited by 332 · see citing works
“Phenols and flavonoids are the most common phytoconstituents of different fruits, vegetables, and medicinal and aromatic plants, which are responsible for antioxidant activities [2].”
Background
Grain Legume Production and Use in European Agricultural Systems
Watson, C. A., Reckling, M., Preißel, S., Bachinger, J., Bergkvist, G., Kuhlman, T., Lindström, K., Nemecek, T., Topp, K., Vanhatalo, A., et al. (2017) · Advances in agronomy · doi:10.1016/bs.agron.2017.03.003 · Cited by 331 · see citing works
In Vitro and in Vivo Antitumoral Effects of Combinations of Polyphenols, or Polyphenols and Anticancer Drugs: Perspectives on Cancer Treatment
Fantini, M. C., Benvenuto, M., Masuelli, L., Frajese, G. V., Tresoldi, I., Modesti, A., & Bei, R. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms16059236 · Cited by 330 · see citing works
Interaction of dietary polyphenols and gut microbiota: Microbial metabolism of polyphenols, influence on the gut microbiota, and implications on host health
Çatalkaya, G., Venema, K., Lucini, L., Rocchetti, G., Delmas, D., Daglia, M., Filippis, A. D., Xiao, H., Quiles, J. L., Xiao, J., et al. (2020) · Food Frontiers · doi:10.1002/fft2.25 · Cited by 339 · see citing works
The Microbiota–Gut–Brain Axis and Alzheimer’s Disease: Neuroinflammation Is to Blame?
Megur, A., Baltriukienė, D., Bukelskienė, V., & Burokas, A. (2020) · Nutrients · doi:10.3390/nu13010037 · Cited by 323 · see citing works
Bioactive potential of fruit and vegetable wastes
Coman, V., Teleky, B., Mitrea, L., Martău, G. A., Szabo, K., Călinoiu, L. F., & Vodnar, D. C. (2019) · Advances in food and nutrition research · doi:10.1016/bs.afnr.2019.07.001 · Cited by 328 · see citing works
Kimchi and Other Widely Consumed Traditional Fermented Foods of Korea: A Review
Patra, J. K., Das, G., Paramithiotis, S., & Shin, H. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01493 · Cited by 320 · see citing works
A minireview of quercetin: from its metabolism to possible mechanisms of its biological activities
Ulusoy, H. G., & Şanlıer, N. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2019.1683810 · Cited by 319 · see citing works
Improving bioaccessibility and bioavailability of phenolic compounds in cereal grains through processing technologies: A concise review
Wang, T., He, F., & Chen, G. (2014) · Journal of Functional Foods · doi:10.1016/j.jff.2014.01.033 · Cited by 316 · see citing works
Bioavailability of phenolic acids
Lafay, S., & Gil‐Izquierdo, Á. (2007) · Phytochemistry Reviews · doi:10.1007/s11101-007-9077-x · Cited by 309 · see citing works
Modulation of endogenous antioxidant system by wine polyphenols in human disease
Rodrigo, R., Miranda, A. L., & Vergara, L. (2010) · Clinica Chimica Acta · doi:10.1016/j.cca.2010.11.034 · Cited by 307 · see citing works
Advanced separation methods of food anthocyanins, isoflavones and flavanols
Valls, J., Millán, S., Marti, M. P. V., Borràs, E., & Arola, L. (2009) · Journal of Chromatography A · doi:10.1016/j.chroma.2009.07.030 · Cited by 303 · see citing works
Nutraceutical Value of Finger Millet [Eleusine coracana (L.) Gaertn.], and Their Improvement Using Omics Approaches
Kumar, A., Metwal, M., Kaur, S., Gupta, A., Puranik, S., Singh, S., Singh, M. P., Gupta, S. C., Babu, B. K., Sood, S., et al. (2016) · Frontiers in Plant Science · doi:10.3389/fpls.2016.00934 · Cited by 302 · see citing works
Sustainable consumption in the circular economy. An analysis of consumers’ purchase intentions for waste-to-value food
Coderoni, S., & Perito, M. A. (2020) · Journal of Cleaner Production · doi:10.1016/j.jclepro.2019.119870 · Cited by 298 · see citing works
Sulforaphane and Other Nutrigenomic Nrf2 Activators: Can the Clinician’s Expectation Be Matched by the Reality?
Houghton, C. A., Fassett, R. G., & Coombes, J. S. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/7857186 · Cited by 303 · see citing works
Dietary Polyphenols, Mediterranean Diet, Prediabetes, and Type 2 Diabetes: A Narrative Review of the Evidence
Guasch-Ferré, M., Merino, J., Sun, Q., Fitó, M., & Salas-Salvadó, J. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/6723931 · Cited by 297 · see citing works
Resveratrol inhibits beta-amyloid oligomeric cytotoxicity but does not prevent oligomer formation
Feng, Y. N., Wang, X., Yang, S., Wang, Y., Zhang, X., Du, X., Sun, X., Zhao, M., Huang, L., & Liu, R. (2009) · NeuroToxicology · doi:10.1016/j.neuro.2009.08.013 · Cited by 297 · see citing works
Dietary fiber and phenolic compounds as functional ingredients: interaction and possible effect after ingestion
Quirós-Sauceda, A. E., Palafox-Carlos, H., Sáyago‐Ayerdi, S. G., Ayala-Zavala, J. F., Bello‐Pérez, L. A., Álvarez-Parrilla, E., la Rosa, L. A. D., González-Córdova, A. F., & González-Aguilar, G. A. (2014) · Food & Function · doi:10.1039/c4fo00073k · Cited by 293 · see citing works
Antioxidants from macroalgae: potential applications in human health and nutrition
Cornish, M. L., & Garbary, D. J. (2010) · ALGAE · doi:10.4490/algae.2010.25.4.155 · Cited by 290 · see citing works
Analysis and Antioxidant Capacity of Anthocyanin Pigments. Part II: Chemical Structure, Color, and Intake of Anthocyanins
Bueno, J. M., Plaza, P. S., Ramos-Escudero, F., Jiménez, A. M., Fett, R., & Asuero, A. G. (2012) · Critical Reviews in Analytical Chemistry · doi:10.1080/10408347.2011.632314 · Cited by 290 · see citing works
Chitosan films and coatings prevent losses of fresh fruit nutritional quality: A review
Kerch, G. (2015) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2015.10.010 · Cited by 281 · see citing works
Trends in LC-MS and LC-HRMS analysis and characterization of polyphenols in food
Lucci, P., Saurina, J., & Núñez, Ó. (2016) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2016.12.006 · Cited by 281 · see citing works
Polyphenols, food and pharma. Current knowledge and directions for future research
Tresserra‐Rimbau, A., Lamuela-Raventós, R. M., & Moreno, J. J. (2018) · Biochemical Pharmacology · doi:10.1016/j.bcp.2018.07.050 · Cited by 280 · see citing works
Chemical Composition, Antibacterial Properties and Mechanism of Action of Essential Oil from Clove Buds against Staphylococcus aureus
Xu, J., Liu, T., Hu, Q. P., & Cao, X.-M. (2016) · Molecules · doi:10.3390/molecules21091194 · Cited by 282 · see citing works
Germinated grains – Sources of bioactive compounds
Donkor, O. N., Stojanovska, L., Ginn, P., Ashton, J., & Vasiljevic, T. (2012) · Food Chemistry · doi:10.1016/j.foodchem.2012.05.058 · Cited by 273 · see citing works
Characterisation of white tea – Comparison to green and black tea
Hilal, Y., & Engelhardt, U. H. (2007) · Journal of Consumer Protection and Food Safety · doi:10.1007/s00003-007-0250-3 · Cited by 272 · see citing works
Interplay between food and gut microbiota in health and disease
Danneskiold‐Samsøe, N. B., Barros, H. D. D. F. Q., dos Santos, R., Bicas, J. L., Cazarin, C. B. B., Madsen, L., Kristiansen, K., Pastore, G. M., Brix, S., & Maróstica, M. R. (2018) · Food Research International · doi:10.1016/j.foodres.2018.07.043 · Cited by 271 · see citing works
Non-extractable polyphenols, a major dietary antioxidant: occurrence, metabolic fate and health effects
Pérez‐Jiménez, J., Diaz-Rubio, M. E., & Saura-Calixto, F. D. (2013) · Nutrition Research Reviews · doi:10.1017/s0954422413000097 · Cited by 268 · see citing works
Polyphenols as dietary supplements: A double-edged sword
Martin, K. R. (2009) · Nutrition and Dietary Supplements · doi:10.2147/nds.s6422 · Cited by 265 · see citing works
Finger Millet (Ragi, Eleusine coracana L.)
Shobana, S., Krishnaswamy, K., Sudha, V., Malleshi, N. G., Anjana, R. M., Palaniappan, L. P., & Mohan, V. (2013) · Advances in food and nutrition research · doi:10.1016/b978-0-12-410540-9.00001-6 · Cited by 263 · see citing works

Authors: Scalbert, A., Manach, C., Morand, C., Rémésy, C., & Jiménez, L.
Affiliations: Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
Institut National de la Recherche Agronomique (FR)
Danone (France) (FR)
ORCID: Scalbert, Augustin
Manach, Claudine
Morand, Christine
Jiménez, Liliana
Venue: Critical Reviews in Food Science and Nutrition
Publisher: Informa UK Limited
Published: 2005-06
Volume: 45
Issue: 4
Pages: 287-306
ISSN: 1040-8398 (ISSN-L)
1549-7852
DOI: 10.1080/1040869059096
OpenAlex: W2152252699
Cited by: 2,999
References: 306
Citations by year: 2026: 74 · 2025: 103 · 2024: 125 · 2023: 148 · 2022: 157 · 2021: 192 · 2020: 212 · 2019: 178 · 2018: 187 · 2017: 174 · 2016: 184 · 2015: 155 · 2014: 185 · 2013: 200 · 2012: 164
FWCI: 40.09
Type: journal article
Language: en
Open access: closed
Locations: Critical Reviews in Food Science and Nutrition (publishedVersion)
PubMed (publishedVersion)
HAL (submittedVersion)
Topics: Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
Keywords: dietary polyphenols, antioxidants, disease prevention, cardiovascular disease, cancer, neurodegenerative diseases, diabetes mellitus, osteoporosis, flavonoids, tea, wine, oxidative stress biomarkers, myocardial infarction, dose-response extrapolation
MeSH terms: Animals, Antioxidants, Cardiovascular Diseases, Diabetes Mellitus, Diet, Female, Flavonoids, Humans, Neoplasms, Phenols, Primary Prevention, Osteoporosis, Postmenopausal, Neurodegenerative Diseases, Polyphenols

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Dietary polyphenols and the prevention of diseases

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Cites

Cited by

Related

Record

About these checks