The DOI matches its Crossref record; 70 of the 70 references it cites were found in a registry or an index.
A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications
Open accessAbstract
The analogs of nitrogen-based heterocycles occupy an exclusive position as a valuable source of therapeutic agents in medicinal chemistry. More than 75% of drugs approved by the FDA and currently available in the market are nitrogen-containing heterocyclic moieties. In the forthcoming decade, a much greater share of new nitrogen-based pharmaceuticals is anticipated. Many new nitrogen-based heterocycles have been designed. The number of novel N-heterocyclic moieties with significant physiological properties and promising applications in medicinal chemistry is ever-growing. In this review, we consolidate the recent advances on novel nitrogen-containing heterocycles and their distinct biological activities, reported over the past one year (2019 to early 2020). This review highlights the trends in the use of nitrogen-based moieties in drug design and the development of different potent and competent candidates against various diseases.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Vitaku, E., Smith, D. T., & Njardarson, J. T. (2014) · Journal of Medicinal Chemistry · doi:10.1021/jm501100b · Cited by 6,418
Natural products as sources of new drugs from 1981 to 2014
Newman, D. J., & Cragg, G. M. (2016) · Journal of Natural Products · doi:10.1021/acs.jnatprod.5b01055 · Cited by 5,858
The influence of drug-like concepts on decision-making in medicinal chemistry
Leeson, P. D., & Springthorpe, B. (2007) · Nature Reviews Drug Discovery · doi:10.1038/nrd2445 · Cited by 2,403
Gordon, E. M., Barrett, R. W., Dower, W. J., Fodor, S. P. A., & Gallop, M. A. (1994) · Journal of Medicinal Chemistry · doi:10.1021/jm00036a001 · Cited by 1,142
Medicinal attributes of 1,2,3-triazoles: Current developments
Dheer, D., Singh, V., & Shankar, R. (2017) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2017.01.010 · Cited by 873
1,2,3-Triazole-containing hybrids as leads in medicinal chemistry: A recent overview
Bozorov, K., Zhao, J., & Aisa, H. A. (2019) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2019.07.005 · Cited by 854
Comprehensive Review in Current Developments of Imidazole-Based Medicinal Chemistry
Zhang, L., Peng, X.-M., Damu, G. L. V., Geng, R.-X., & Zhou, C.-H. (2014) · Medicinal Research Reviews · doi:10.1002/med.21290 · Cited by 793
Review: biologically active pyrazole derivatives
Ansari, A., Ali, A., Asif, M., & Shamsuzzaman, S. (2017) · New Journal of Chemistry · doi:10.1039/c6nj03181a · Cited by 786
Martins, P., Jesus, J., Santos, S., Raposo, L., Roma-Rodrigues, C., Baptista, P., & Fernandes, A. (2015) · Molecules · doi:10.3390/molecules200916852 · Cited by 716
Xu, Z., Zhao, S.-J., & Liu, Y. (2019) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2019.111700 · Cited by 520
Cited by
Photocatalysis in the Life Science Industry
Candish, L., Collins, K. D., Cook, G. C., Douglas, J. J., Gómez-Suárez, A., Jolit, A., & Keess, S. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00416 · Cited by 428
Pratley, C., Fenner, S., & Murphy, J. A. (2022) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00831 · Cited by 422
Methods for nitrogen activation by reduction and oxidation
Iriawan, H., Andersen, S. Z., Zhang, X., Comer, B. M., Barrio, J., Chen, P., Medford, A. J., Stephens, I. E. L., Chorkendorff, I., & Shao-Horn, Y. (2021) · Nature Reviews Methods Primers · doi:10.1038/s43586-021-00053-y · Cited by 294
Metadata
- Authors
- Kerru, N., Gummidi, L., Maddila, S., Gangu, K. K., & Jonnalagadda, S. B.
- Venue
- Molecules
- Publisher
- MDPI AG
- Published
- 2020-04-20
- Volume
- 25
- Issue
- 8
- Pages
- 1909
- ISSN
- 1420-3049 (ISSN-L)
- OpenAlex
- W3016762617
- Cited by
- 1,716
- References
- 70
- FWCI
- 72.05
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications. https://app.cochat.ai/papers/10.3390/molecules25081909
- The paper
- Kerru, N., Gummidi, L., Maddila, S., Gangu, K. K., & Jonnalagadda, S. B. (2020). A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications. Molecules. https://doi.org/10.3390/molecules25081909
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
